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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Arhgap1 (spascer ID:228359)

Gene summary for Arhgap1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Arhgap1
	Gene ID	228359
	Gene name	Rho GTPase activating protein 1
	Synonyms	B230365D05Rik\|C76222\|Cdc42GAP\|p50rhoGAP
	Cytomap	2\|2 E1
	Type of gene	protein-coding
	Description	rho GTPase-activating protein 1rho-type GTPase-activating protein 1
	Modification date	20220424
	UniProtAcc	Q5FWK3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Arhgap1	GO:0005096	GTPase activator activity	21873635	Function
Arhgap1	GO:0005737	cytoplasm	21873635	Component
Arhgap1	GO:0007264	small GTPase mediated signal transduction	21873635	Process
Arhgap1	GO:2001136	negative regulation of endocytic recycling	21873635	Process

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Spatial pattern events for Arhgap1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Arhgap1	Mouse	Brain	S1	34413515	1.85e-08
Arhgap1	Mouse	Brain	S2	34413515	1.56e-15
Arhgap1	Mouse	Brain	S4	34413515	2.11e-08
Arhgap1	Mouse	Brain	S6	34413515	1.46e-15
Arhgap1	Mouse	Brain	S7	34413515	5.47e-15
Arhgap1	Mouse	Brain	34A	32637622	2.38e-06
Arhgap1	Mouse	Brain	rep_1	35141374	8.16e-10
Arhgap1	Mouse	Brain	rep_2	35141374	4.94e-07
Arhgap1	Mouse	Brain	rep_3	35141374	2.81e-14
Arhgap1	Mouse	Brain	rep_4	35141374	8.65e-08
Arhgap1	Mouse	Embryo	rep_2	33188776	2.87e-11
Arhgap1	Mouse	Kidney	CLP	34003797	2.19e-15
Arhgap1	Mouse	Kidney	IRI	34003797	5.33e-07
Arhgap1	Mouse	Kidney	rep_1	34853151	2.42e-15
Arhgap1	Mouse	Brain	rep_1	33469025	1.30e-15
Arhgap1	Mouse	Brain	rep_1	35027729	1.66e-15
Arhgap1	Mouse	Brain	rep_2	35027729	2.83e-15
Arhgap1	Mouse	Brain	rep_3	35027729	1.32e-15
Arhgap1	Mouse	Brain	rep_4	35027729	7.74e-09
Arhgap1	Mouse	Brain	rep_5	35027729	5.00e-15
Arhgap1	Mouse	Intestine	rep_2	35149721	4.58e-08
Arhgap1	Mouse	Intestine	rep_4	35149721	3.90e-15
Arhgap1	Mouse	Lymph	B1	0	1.58e-06
Arhgap1	Mouse	Lung	rep_2	35290801	5.34e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has Arhgap1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Arhgap1	GOBP_Cation_Transport	Mouse	Spinal cord	CN94_E1	5.8e-06
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Spinal cord	CN94_E1	1.7e-07
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Spinal cord	CN94_E1	8.4e-06
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Spinal cord	CN94_E1	5.3e-07
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Spinal cord	CN94_E1	5.3e-06
Arhgap1	GOBP_Endosomal_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-08
Arhgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Arhgap1	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Arhgap1	GOBP_Iron_Ion_Transport	Mouse	Spinal cord	L7CN45_C1	4.3e-09
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Arhgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	1.8e-08
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Spinal cord	L7CN45_C1	1.3e-07
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	2.0e-06
Arhgap1	GOBP_Transition_Metal_Ion_Transport	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Arhgap1	GOBP_Transferrin_Transport	Mouse	Spinal cord	L7CN47_D1	2.2e-06
Arhgap1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Spinal cord	L8CN17_E1	6.9e-06
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_27	3.9e-05
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	rep_27	5.0e-06
Arhgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_27	4.2e-05
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_27	6.4e-05
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Brain	rep_71	5.2e-06
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Brain	rep_71	6.2e-05
Arhgap1	GOBP_Cation_Transport	Mouse	Brain	rep_1	1.5e-22
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Brain	rep_1	1.6e-15
Arhgap1	GOBP_Endosomal_Transport	Mouse	Brain	rep_1	8.9e-24
Arhgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Arhgap1	GOBP_Negative_Regulation_Of_Transport	Mouse	Brain	rep_1	1.2e-09
Arhgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	2.1e-36
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_1	1.0e-11
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_1	1.1e-11
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	rep_1	3.0e-15
Arhgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	5.6e-32
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.2e-13
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Brain	rep_1	3.9e-15
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	rep_1	5.0e-23
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.1e-22
Arhgap1	GOBP_Transferrin_Transport	Mouse	Brain	rep_1	4.5e-14
Arhgap1	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Arhgap1	GOBP_Negative_Regulation_Of_Intracellular_Transport	Mouse	Brain	rep_3	3.1e-49
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Arhgap1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Arhgap1	GOBP_Regulation_Of_Intracellular_Transport	Mouse	Brain	rep_3	2.8e-123
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Brain	rep_3	2.0e-147
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Brain	rep_5	1.1e-85
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Embryo	rep_6	2.6e-10
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Embryo	rep_6	4.2e-07
Arhgap1	GOBP_Iron_Ion_Transport	Mouse	Embryo	rep_14	5.3e-50
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Arhgap1	GOBP_Transferrin_Transport	Mouse	Embryo	rep_14	3.1e-62
Arhgap1	GOBP_Transition_Metal_Ion_Transport	Mouse	Embryo	rep_14	1.4e-32
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	1.6e-15
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Embryo	rep_1	3.8e-34
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Embryo	rep_3	2.7e-14
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Arhgap1	GOBP_Negative_Regulation_Of_Transport	Mouse	Embryo	rep_4	7.5e-23
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.4e-48
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Kidney	Nep	2.6e-47
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Kidney	Nep	2.7e-48
Arhgap1	GOBP_Cation_Transport	Mouse	Kidney	rep_2	5.9e-23
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Kidney	rep_2	7.9e-154
Arhgap1	GOBP_Endosomal_Transport	Mouse	Kidney	rep_2	1.5e-111
Arhgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Arhgap1	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Arhgap1	GOBP_Iron_Ion_Transport	Mouse	Kidney	rep_2	1.0e-34
Arhgap1	GOBP_Negative_Regulation_Of_Transport	Mouse	Kidney	rep_2	4.0e-19
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Arhgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.1e-81
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	3.6e-50
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	3.5e-92
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Kidney	rep_2	2.8e-40
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Kidney	rep_2	1.5e-25
Arhgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	1.2e-71
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Arhgap1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.0e-93
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Kidney	rep_2	2.4e-58
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Kidney	rep_2	8.7e-134
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Kidney	rep_2	2.4e-81
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.2e-75
Arhgap1	GOBP_Transferrin_Transport	Mouse	Kidney	rep_2	2.6e-61
Arhgap1	GOBP_Transition_Metal_Ion_Transport	Mouse	Kidney	rep_2	1.5e-42
Arhgap1	GOBP_Negative_Regulation_Of_Intracellular_Transport	Mouse	Liver	CN16-D2	6.4e-12
Arhgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN16-D2	1.9e-10
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Liver	CN16-D2	1.3e-07
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Liver	CN73-C1	1.8e-07
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Liver	rep_15	6.9e-10
Arhgap1	GOBP_Cation_Transport	Mouse	Liver	rep_16	1.2e-18
Arhgap1	GOBP_Transferrin_Transport	Mouse	Liver	rep_16	7.2e-23
Arhgap1	GOBP_Transferrin_Transport	Mouse	Brain	rep_1	1.0e-07
Arhgap1	GOBP_Iron_Ion_Transport	Mouse	Intestine	rep_2	1.0e-38
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Lymph	MS-1	1.4e-08
Arhgap1	GOBP_Endosomal_Transport	Mouse	Lymph	MS-1	9.8e-11
Arhgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Arhgap1	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Arhgap1	GOBP_Iron_Ion_Transport	Mouse	Lymph	MS-1	3.4e-12
Arhgap1	GOBP_Negative_Regulation_Of_Intracellular_Transport	Mouse	Lymph	MS-1	4.3e-11
Arhgap1	GOBP_Negative_Regulation_Of_Transport	Mouse	Lymph	MS-1	1.0e-17
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	1.1e-08
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Lymph	MS-1	1.5e-07
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Arhgap1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Arhgap1	GOBP_Regulation_Of_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Lymph	MS-1	1.4e-12
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Lymph	MS-1	1.8e-09
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Lymph	MS-1	8.4e-07
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-10
Arhgap1	GOBP_Transferrin_Transport	Mouse	Lymph	MS-1	7.2e-07
Arhgap1	GOBP_Transition_Metal_Ion_Transport	Mouse	Lymph	MS-1	1.4e-12
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Brain	rep_4	6.9e-14
Arhgap1	GOBP_Endosomal_Transport	Mouse	Brain	rep_4	2.6e-13
Arhgap1	GOBP_Negative_Regulation_Of_Intracellular_Transport	Mouse	Brain	rep_4	8.1e-26
Arhgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_4	7.8e-12
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_4	6.8e-16
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	rep_4	5.3e-09
Arhgap1	GOBP_Cation_Transport	Mouse	Brain	HP_ad_rep7	7.5e-07
Arhgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Arhgap1	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Arhgap1	GOBP_Negative_Regulation_Of_Transport	Mouse	Brain	HP_ad_rep7	1.7e-07
Arhgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Arhgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_ad_rep7	4.8e-07
Arhgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Arhgap1	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	HP_ad_rep7	2.0e-07
Arhgap1	GOBP_Regulation_Of_Transport	Mouse	Brain	HP_ad_rep7	9.2e-09
Arhgap1	GOBP_Rho_Protein_Signal_Transduction	Mouse	Brain	HP_ad_rep7	1.7e-07
Arhgap1	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_ad_rep7	4.6e-08
Arhgap1	GOBP_Transferrin_Transport	Mouse	Brain	HP_ad_rep7	3.5e-08
Arhgap1	GOBP_Endocytic_Recycling	Mouse	Brain	HP_polb_rep9	2.8e-10
Arhgap1	GOBP_Endosomal_Transport	Mouse	Brain	HP_polb_rep9	2.8e-14
Arhgap1	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	7.2e-09
Arhgap1	GOBP_Regulation_Of_Endocytic_Recycling	Mouse	Brain	HP_polb_rep9	6.9e-07
Arhgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_polb_rep9	4.2e-09
Arhgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Arhgap1	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Arhgap1	GOBP_Regulation_Of_Intracellular_Transport	Mouse	Brain	HP_polb_rep9	2.7e-09
Arhgap1	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_polb_rep9	5.2e-07
Arhgap1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	HP_polb_rep9	9.9e-09
Arhgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_wt_rep2	2.1e-07

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Arhgap1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Arhgap1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Arhgap1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Arhgap1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Arhgap1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Arhgap1	C0036341	Schizophrenia	1	PSYGENET