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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Epc2 (spascer ID:227867)

Gene summary for Epc2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Epc2
	Gene ID	227867
	Gene name	enhancer of polycomb homolog 2
	Synonyms	5830499L14\|D2Ertd694e
	Cytomap	2 C1.1\|2 28.62 cM
	Type of gene	protein-coding
	Description	enhancer of polycomb homolog 2
	Modification date	20220424
	UniProtAcc	Q8C0I4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Epc2	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process
Epc2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex	21873635	Component

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Spatial pattern events for Epc2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Epc2	Mouse	Brain	S2	34413515	1.56e-15
Epc2	Mouse	Brain	S3	34413515	1.23e-09
Epc2	Mouse	Brain	S4	34413515	2.43e-06
Epc2	Mouse	Brain	S6	34413515	2.91e-11
Epc2	Mouse	Brain	S7	34413515	1.55e-15
Epc2	Mouse	Brain	rep_4	35141374	1.94e-11
Epc2	Mouse	Embryo	4E	34210887	1.76e-06
Epc2	Mouse	Brain	rep_5	35027729	2.15e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Epc2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Epc2	GOBP_Peptidyl_Lysine_Acetylation	Mouse	Spinal cord	CN94_E1	1.4e-06
Epc2	GOBP_Protein_Acetylation	Mouse	Spinal cord	CN94_E1	7.5e-06
Epc2	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Epc2	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Epc2	GOBP_Dna_Repair	Mouse	Spinal cord	L7CN45_C1	9.4e-06
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Spinal cord	L7CN45_C1	9.7e-08
Epc2	GOBP_Protein_Acylation	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Brain	rep_27	4.2e-05
Epc2	GOBP_Protein_Acetylation	Mouse	Brain	rep_72	4.8e-06
Epc2	GOBP_Protein_Acylation	Mouse	Brain	rep_72	5.8e-05
Epc2	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	rep_1	9.0e-07
Epc2	GOBP_Peptidyl_Lysine_Acetylation	Mouse	Brain	rep_1	7.8e-25
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Brain	rep_1	1.1e-21
Epc2	GOBP_Protein_Acetylation	Mouse	Brain	rep_1	8.1e-27
Epc2	GOBP_Protein_Acylation	Mouse	Brain	rep_1	1.4e-26
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Epc2	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Epc2	GOBP_Dna_Repair	Mouse	Brain	rep_3	4.0e-216
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Epc2	GOBP_Dna_Repair	Mouse	Embryo	rep_2	1.6e-282
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Embryo	rep_2	3.3e-11
Epc2	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Epc2	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Embryo	rep_3	0.0e+00
Epc2	GOBP_Peptidyl_Lysine_Acetylation	Mouse	Embryo	rep_3	0.0e+00
Epc2	GOBP_Protein_Acetylation	Mouse	Embryo	rep_3	0.0e+00
Epc2	GOBP_Protein_Acylation	Mouse	Embryo	rep_3	0.0e+00
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Epc2	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Epc2	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Epc2	GOBP_Dna_Repair	Mouse	Kidney	rep_2	5.5e-70
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Kidney	rep_2	6.9e-23
Epc2	GOBP_Peptidyl_Lysine_Acetylation	Mouse	Kidney	rep_2	8.0e-37
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Kidney	rep_2	5.8e-39
Epc2	GOBP_Protein_Acetylation	Mouse	Kidney	rep_2	7.0e-39
Epc2	GOBP_Protein_Acylation	Mouse	Kidney	rep_2	1.1e-58
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Epc2	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Epc2	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Lymph	MS-1	1.2e-13
Epc2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Epc2	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Epc2	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Epc2	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Epc2	GOBP_Dna_Repair	Mouse	Brain	HP_ad_rep7	2.4e-12
Epc2	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	HP_ad_rep7	3.2e-08
Epc2	GOBP_Peptidyl_Lysine_Modification	Mouse	Brain	HP_ad_rep7	1.7e-10
Epc2	GOBP_Protein_Acetylation	Mouse	Brain	HP_ad_rep7	1.1e-09
Epc2	GOBP_Protein_Acylation	Mouse	Brain	HP_ad_rep7	2.6e-07
Epc2	GOBP_Peptidyl_Lysine_Acetylation	Mouse	Brain	HP_polb_rep9	6.0e-07

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Epc2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Epc2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Epc2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Epc2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Epc2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Epc2	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human