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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Rabgap1 (spascer ID:227800)

Gene summary for Rabgap1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Rabgap1
	Gene ID	227800
	Gene name	RAB GTPase activating protein 1
	Synonyms	Gapcena\|mKIAA4104
	Cytomap	2\|2 B
	Type of gene	protein-coding
	Description	rab GTPase-activating protein 1GAP and centrosome-associated proteinrab6 GTPase activating protein (GAP and centrosome-associated)rab6 GTPase-activating protein GAPCenA
	Modification date	20220424
	UniProtAcc	A2AWA9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Rabgap1	GO:0005096	GTPase activator activity	21873635	Function
Rabgap1	GO:0090630	activation of GTPase activity	21873635	Process

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Spatial pattern events for Rabgap1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Rabgap1	Mouse	Brain	S4	34413515	3.12e-10
Rabgap1	Mouse	Brain	rep_3	35141374	7.74e-08
Rabgap1	Mouse	Brain	rep_5	35141374	5.12e-06
Rabgap1	Mouse	Brain	rep_6	35141374	4.28e-11
Rabgap1	Mouse	Embryo	rep_4	33188776	2.60e-07
Rabgap1	Mouse	Brain	rep_3	35027729	8.98e-11
Rabgap1	Mouse	Testicle	rep_4	34731600	1.46e-15
Rabgap1	Mouse	Brain	rep_7	35210624	4.60e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Rabgap1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Spinal cord	CN93_D2	2.8e-06
Rabgap1	GOBP_Cell_Cycle	Mouse	Spinal cord	CN94_E1	1.1e-06
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Rabgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Rabgap1	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Rabgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	1.8e-08
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Rabgap1	GOBP_Cell_Cycle	Mouse	Brain	rep_27	8.4e-07
Rabgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_27	4.2e-05
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Brain	rep_1	4.7e-17
Rabgap1	GOBP_Cell_Cycle	Mouse	Brain	rep_1	7.0e-10
Rabgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Rabgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	2.1e-36
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_1	1.0e-11
Rabgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	5.6e-32
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Brain	rep_3	2.7e-132
Rabgap1	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Embryo	rep_14	1.4e-30
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	1.6e-15
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Embryo	rep_4	1.1e-39
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.4e-48
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.2e-104
Rabgap1	GOBP_Cell_Cycle	Mouse	Kidney	rep_2	1.0e-24
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Rabgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Kidney	rep_2	7.5e-54
Rabgap1	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Rabgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.1e-81
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	3.6e-50
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Rabgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	1.2e-71
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Rabgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN16-D2	1.9e-10
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Lymph	MS-1	1.2e-11
Rabgap1	GOBP_Cell_Cycle	Mouse	Lymph	MS-1	1.3e-07
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Rabgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Lymph	MS-1	3.0e-17
Rabgap1	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Rabgap1	GOBP_Activation_Of_Gtpase_Activity	Mouse	Brain	rep_4	5.3e-15
Rabgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_4	7.8e-12
Rabgap1	GOBP_Cell_Cycle	Mouse	Brain	HP_ad_rep7	6.6e-08
Rabgap1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Rabgap1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Rabgap1	GOBP_Intracellular_Protein_Transport	Mouse	Brain	HP_ad_rep7	3.6e-08
Rabgap1	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Rabgap1	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Rabgap1	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_ad_rep7	4.8e-07
Rabgap1	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Rabgap1	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_polb_rep9	4.2e-09
Rabgap1	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Rabgap1	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_wt_rep2	2.1e-07

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Rabgap1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Rabgap1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Rabgap1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Rabgap1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Rabgap1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source