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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Lamc1 (spascer ID:226519)

Gene summary for Lamc1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Lamc1
	Gene ID	226519
	Gene name	laminin, gamma 1
	Synonyms	Lamb2
	Cytomap	1 G3\|1 65.3 cM
	Type of gene	protein-coding
	Description	laminin subunit gamma-1S-LAM gammaS-laminin subunit gammalaminin B2 chainlaminin-1 subunit gammalaminin-10 subunit gammalaminin-11 subunit gammalaminin-2 subunit gammalaminin-3 subunit gammalaminin-4 subunit gammalaminin-6 subunit gammalaminin-
	Modification date	20220426
	UniProtAcc	P02468

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Lamc1	GO:0005201	extracellular matrix structural constituent	21873635	Function
Lamc1	GO:0005604	basement membrane	21873635	Component
Lamc1	GO:0009887	animal organ morphogenesis	21873635	Process
Lamc1	GO:0009888	tissue development	21873635	Process
Lamc1	GO:0016477	cell migration	21873635	Process
Lamc1	GO:0034446	substrate adhesion-dependent cell spreading	21873635	Process

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Spatial pattern events for Lamc1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Lamc1	Mouse	Brain	S2	34413515	2.88e-10
Lamc1	Mouse	Brain	S3	34413515	1.36e-12
Lamc1	Mouse	Brain	S4	34413515	3.37e-06
Lamc1	Mouse	Brain	S6	34413515	1.13e-11
Lamc1	Mouse	Embryo	3D	34210887	8.23e-06
Lamc1	Mouse	Embryo	4E	34210887	3.61e-06
Lamc1	Mouse	Embryo	rep_4	33188776	3.32e-09
Lamc1	Mouse	Kidney	CLP	34003797	2.19e-15
Lamc1	Mouse	Kidney	IRI	34003797	3.92e-15
Lamc1	Mouse	Kidney	Sham	34003797	3.08e-14
Lamc1	Mouse	Brain	rep_3	35027729	1.73e-08
Lamc1	Mouse	Intestine	rep_2	35149721	3.44e-15
Lamc1	Mouse	Lymph	A1	0	4.27e-10
Lamc1	Mouse	Lymph	B1	0	3.66e-15
Lamc1	Mouse	Lung	rep_1	35290801	1.07e-07
Lamc1	Mouse	Lung	rep_3	35290801	1.54e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Brain_rep_3_H&E
Lung_rep_1_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Lamc1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Lamc1	GOBP_Anatomical_Structure_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Spinal cord	CN94_E1	9.1e-06
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Spinal cord	CN94_E1	1.2e-06
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Spinal cord	CN94_E1	4.0e-08
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Spinal cord	CN94_E1	2.3e-07
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Spinal cord	L7bCN02_E1	4.0e-06
Lamc1	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Spinal cord	L7CN45_C1	2.8e-06
Lamc1	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Lamc1	GOBP_Endoderm_Development	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Spinal cord	L7CN45_C1	4.7e-07
Lamc1	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Lamc1	GOBP_Maintenance_Of_Blood_Brain_Barrier	Mouse	Spinal cord	L7CN45_C1	4.4e-07
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Spinal cord	L7CN45_C1	5.2e-06
Lamc1	GOBP_Cell_Substrate_Adhesion	Mouse	Spinal cord	L7CN97_E2	2.2e-06
Lamc1	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Lamc1	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Spinal cord	L8CN14_E2	8.1e-17
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_27	5.8e-05
Lamc1	GOBP_Endoderm_Development	Mouse	Brain	rep_41	3.1e-08
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Brain	rep_41	3.5e-05
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	rep_72	3.4e-06
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Brain	rep_1	1.2e-14
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_1	1.5e-30
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Brain	rep_1	5.7e-33
Lamc1	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Brain	rep_1	4.6e-07
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Brain	rep_1	4.3e-11
Lamc1	GOBP_Anatomical_Structure_Homeostasis	Mouse	Brain	rep_3	1.8e-76
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Lamc1	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Lamc1	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Lamc1	GOBP_Cell_Substrate_Adhesion	Mouse	Brain	rep_3	1.8e-27
Lamc1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Brain	rep_3	1.3e-07
Lamc1	GOBP_Endoderm_Development	Mouse	Brain	rep_3	1.8e-94
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	rep_3	1.4e-179
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	rep_3	8.9e-180
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Brain	rep_3	2.6e-91
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Brain	rep_3	8.9e-70
Lamc1	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	rep_3	6.7e-70
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Brain	rep_3	8.8e-172
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Brain	rep_3	6.2e-128
Lamc1	GOBP_Maintenance_Of_Blood_Brain_Barrier	Mouse	Brain	rep_4	2.8e-25
Lamc1	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Embryo	rep_6	1.0e-10
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Embryo	rep_14	8.5e-42
Lamc1	GOBP_Maintenance_Of_Blood_Brain_Barrier	Mouse	Embryo	rep_14	7.8e-37
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Embryo	rep_14	2.7e-16
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Embryo	rep_14	1.7e-45
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Lamc1	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Lamc1	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Lamc1	GOBP_Cell_Substrate_Adhesion	Mouse	Embryo	rep_1	2.0e-34
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Embryo	rep_1	0.0e+00
Lamc1	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Lamc1	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Embryo	rep_1	7.9e-50
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Embryo	rep_1	7.1e-65
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Embryo	rep_1	1.7e-112
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Embryo	rep_2	9.1e-35
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Embryo	rep_3	4.6e-28
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Embryo	rep_3	1.7e-20
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Embryo	rep_6	1.1e-18
Lamc1	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Lamc1	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Kidney	Nep	2.0e-14
Lamc1	GOBP_Anatomical_Structure_Homeostasis	Mouse	Kidney	rep_2	8.4e-22
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Lamc1	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Kidney	rep_2	5.4e-41
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Kidney	rep_2	6.2e-52
Lamc1	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Kidney	rep_2	7.8e-42
Lamc1	GOBP_Cell_Substrate_Adhesion	Mouse	Kidney	rep_2	4.0e-46
Lamc1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Kidney	rep_2	5.7e-41
Lamc1	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Lamc1	GOBP_Endoderm_Development	Mouse	Kidney	rep_2	3.0e-25
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Kidney	rep_2	1.8e-43
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Kidney	rep_2	5.6e-85
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Kidney	rep_2	7.7e-108
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Kidney	rep_2	1.3e-43
Lamc1	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Lamc1	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Kidney	rep_2	1.3e-51
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Kidney	rep_2	3.8e-57
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Kidney	rep_2	7.2e-84
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Kidney	rep_2	7.7e-70
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Liver	CN16-D1	1.7e-08
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Liver	CN16-D2	1.4e-10
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Liver	CN73-C1	1.7e-07
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Liver	CN73-C1	1.4e-08
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	CN73-C1	5.5e-08
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Liver	CN73-C1	9.0e-07
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Liver	rep_15	5.8e-09
Lamc1	GOBP_Maintenance_Of_Blood_Brain_Barrier	Mouse	Liver	rep_15	7.9e-18
Lamc1	GOBP_Anatomical_Structure_Homeostasis	Mouse	Liver	rep_16	8.1e-23
Lamc1	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Liver	rep_16	1.6e-07
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Liver	rep_16	5.1e-08
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	rep_16	4.4e-20
Lamc1	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Lamc1	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Lamc1	GOBP_Anatomical_Structure_Homeostasis	Mouse	Lymph	MS-1	1.1e-14
Lamc1	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Lamc1	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Lymph	MS-1	7.9e-08
Lamc1	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Lymph	MS-1	2.1e-10
Lamc1	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Lamc1	GOBP_Endoderm_Development	Mouse	Lymph	MS-1	1.5e-08
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Lymph	MS-1	1.0e-07
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lymph	MS-1	6.5e-12
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Lymph	MS-1	1.2e-12
Lamc1	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Lamc1	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Lymph	MS-1	1.1e-12
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Lymph	MS-1	2.3e-12
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Lymph	MS-1	3.9e-09
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Lymph	MS-1	1.9e-09
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Lymph	PBS	6.0e-07
Lamc1	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lung	rep_1	1.3e-11
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Lung	rep_1	1.8e-15
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Brain	rep_4	6.5e-07
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_4	3.7e-07
Lamc1	GOBP_Cell_Junction_Assembly	Mouse	Brain	HP_ad_rep7	1.3e-11
Lamc1	GOBP_Cell_Junction_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Lamc1	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Lamc1	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Lamc1	GOBP_Cell_Morphogenesis_Involved_In_Differentiation	Mouse	Brain	HP_ad_rep7	8.1e-09
Lamc1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Brain	HP_ad_rep7	4.0e-10
Lamc1	GOBP_Endoderm_Development	Mouse	Brain	HP_ad_rep7	1.3e-07
Lamc1	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	HP_ad_rep7	8.1e-09
Lamc1	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	HP_ad_rep7	1.9e-11
Lamc1	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Lamc1	GOBP_Positive_Regulation_Of_Cell_Population_Proliferation	Mouse	Brain	HP_ad_rep7	1.9e-10
Lamc1	GOBP_Positive_Regulation_Of_Epithelial_Cell_Proliferation	Mouse	Brain	HP_ad_rep7	3.3e-09
Lamc1	GOBP_Substrate_Adhesion_Dependent_Cell_Spreading	Mouse	Brain	HP_ad_rep7	1.3e-09
Lamc1	GOBP_Extracellular_Matrix_Disassembly	Mouse	Brain	HP_adpolb_rep1	6.8e-14
Lamc1	GOBP_Hemidesmosome_Assembly	Mouse	Brain	HP_adpolb_rep5	1.1e-07
Lamc1	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Lamc1	GOBP_Cell_Substrate_Adhesion	Mouse	Brain	HP_polb_rep9	3.3e-07
Lamc1	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Lamc1	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Lamc1	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	HP_polb_rep9	3.2e-07
Lamc1	GOBP_Post_Translational_Protein_Modification	Mouse	Brain	HP_polb_rep9	5.1e-14

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Lamc1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Lamc1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Lamc1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Lamc1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Lamc1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Lamc1	C0003493	Aortic Diseases	1	CTD_human
Lamc1	C0024796	Marfan Syndrome	1	CTD_human
Lamc1	C0033578	Prostatic Neoplasms	1	CTD_human
Lamc1	C0376358	Malignant neoplasm of prostate	1	CTD_human
Lamc1	C4721845	Marfan Syndrome, Type I	1	CTD_human