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Spatial pattern gene: Nmnat2 (spascer ID:226518) |
Gene summary for Nmnat2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Nmnat2 | Gene ID | 226518 |
| Gene name | nicotinamide nucleotide adenylyltransferase 2 |
| Synonyms | AI843915|D030041I09Rik|PNAT1|PNAT2 |
| Cytomap | 1|1 G3 |
| Type of gene | protein-coding |
| Description | nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2NMN adenylyltransferase 2NMN/NaMN adenylyltransferase 2bladnaMN adenylyltransferase 1naMN adenylyltransferase 2nicotinamide mononucleotide adenylyltransferase 2nicotinate-nucleotide ad |
| Modification date | 20220424 |
| UniProtAcc | Q8BNJ3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Nmnat2 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity | 21873635 | Function |
| Nmnat2 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity | 21873635 | Function |
| Nmnat2 | GO:0005794 | Golgi apparatus | 21873635 | Component |
| Nmnat2 | GO:0009435 | NAD biosynthetic process | 21873635 | Process |
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Spatial pattern events for Nmnat2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Nmnat2 | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Nmnat2 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Nmnat2 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Nmnat2 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Nmnat2 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Nmnat2 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Nmnat2 | Mouse | Brain | 13B | 32637622 | 7.10e-08 |
| Nmnat2 | Mouse | Brain | 17A | 32637622 | 2.03e-14 |
| Nmnat2 | Mouse | Brain | 18A | 32637622 | 4.65e-07 |
| Nmnat2 | Mouse | Brain | 18B | 32637622 | 4.71e-09 |
| Nmnat2 | Mouse | Brain | 19A | 32637622 | 7.56e-10 |
| Nmnat2 | Mouse | Brain | 19B | 32637622 | 2.22e-14 |
| Nmnat2 | Mouse | Brain | 21A | 32637622 | 4.17e-14 |
| Nmnat2 | Mouse | Brain | 21B | 32637622 | 4.91e-07 |
| Nmnat2 | Mouse | Brain | 22A | 32637622 | 4.71e-11 |
| Nmnat2 | Mouse | Brain | 22B | 32637622 | 2.87e-13 |
| Nmnat2 | Mouse | Brain | 23A | 32637622 | 8.28e-08 |
| Nmnat2 | Mouse | Brain | 23B | 32637622 | 1.56e-12 |
| Nmnat2 | Mouse | Brain | 24B | 32637622 | 7.37e-09 |
| Nmnat2 | Mouse | Brain | 26A | 32637622 | 2.60e-08 |
| Nmnat2 | Mouse | Brain | 26B | 32637622 | 1.06e-08 |
| Nmnat2 | Mouse | Brain | 27A | 32637622 | 6.61e-06 |
| Nmnat2 | Mouse | Brain | 28A | 32637622 | 1.02e-09 |
| Nmnat2 | Mouse | Brain | 28B | 32637622 | 1.46e-06 |
| Nmnat2 | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Nmnat2 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Nmnat2 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Nmnat2 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Nmnat2 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Nmnat2 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Nmnat2 | Mouse | Embryo | 1E | 34210887 | 7.42e-08 |
| Nmnat2 | Mouse | Embryo | 2H | 34210887 | 5.31e-15 |
| Nmnat2 | Mouse | Embryo | 4E | 34210887 | 4.53e-15 |
| Nmnat2 | Mouse | Embryo | rep_2 | 33188776 | 1.59e-07 |
| Nmnat2 | Mouse | Embryo | rep_5 | 33188776 | 3.26e-13 |
| Nmnat2 | Mouse | Brain | rep_1 | 33469025 | 3.13e-09 |
| Nmnat2 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Nmnat2 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Nmnat2 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Nmnat2 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Nmnat2 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Nmnat2 | Mouse | Brain | B05_D2 | 32702314 | 7.31e-06 |
| Nmnat2 | Mouse | Brain | B07_C2 | 32702314 | 5.42e-06 |
| Nmnat2 | Mouse | Brain | N02_C1 | 32702314 | 2.60e-10 |
| Nmnat2 | Mouse | Brain | N02_D1 | 32702314 | 4.61e-06 |
| Nmnat2 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Nmnat2 | Mouse | Brain | rep_4 | 35210624 | 1.55e-06 |
| Nmnat2 | Mouse | Brain | rep_5 | 35210624 | 5.41e-11 |
| Nmnat2 | Mouse | Brain | rep_7 | 35210624 | 1.87e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B05_D2_H&E  |  |
Brain_B07_C2_H&E  |  |
Brain_N02_C1_H&E  |  |
Brain_N02_D1_H&E  |  |
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Spatial pattern pathway has Nmnat2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Spinal cord | CN93_D2 | 4.3e-06 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Spinal cord | L7bCN02_E1 | 6.6e-06 |
| Nmnat2 | GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 1.1e-07 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 1.4e-07 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 5.6e-08 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 1.7e-07 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 2.0e-07 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 1.7e-07 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Spinal cord | L7CN85_E1 | 4.1e-08 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Brain | rep_1 | 3.5e-11 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Brain | rep_3 | 3.2e-22 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.9e-144 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.9e-25 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Brain | rep_3 | 8.1e-43 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Brain | rep_3 | 9.3e-98 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_3 | 1.8e-150 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Brain | rep_3 | 2.7e-19 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Embryo | rep_14 | 2.4e-39 |
| Nmnat2 | GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process | Mouse | Embryo | rep_14 | 1.8e-12 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Embryo | rep_14 | 4.8e-21 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Embryo | rep_14 | 2.4e-12 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Embryo | rep_14 | 1.8e-11 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Embryo | rep_14 | 2.0e-09 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Embryo | rep_14 | 3.6e-92 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_14 | 7.5e-67 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Embryo | rep_1 | 1.4e-55 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Kidney | rep_2 | 1.1e-173 |
| Nmnat2 | GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process | Mouse | Kidney | rep_2 | 2.4e-27 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Kidney | rep_2 | 4.6e-07 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Kidney | rep_2 | 8.9e-78 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Kidney | rep_2 | 1.2e-09 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Kidney | rep_2 | 1.7e-41 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Kidney | rep_2 | 1.2e-41 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 1.6e-68 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Kidney | rep_2 | 1.8e-43 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Liver | CN16-E1 | 3.4e-08 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Liver | CN16-E1 | 1.7e-10 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Liver | CN73-C1 | 6.5e-09 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Liver | CN73-C1 | 2.5e-07 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Liver | CN73-C1 | 3.0e-11 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Liver | rep_16 | 1.6e-07 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Liver | rep_16 | 1.6e-18 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Lymph | MS-1 | 1.4e-10 |
| Nmnat2 | GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process | Mouse | Lymph | MS-1 | 2.7e-09 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Lymph | MS-1 | 3.6e-07 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Lymph | MS-1 | 1.4e-09 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Lymph | MS-1 | 6.7e-07 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Lymph | MS-1 | 7.3e-07 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Lymph | MS-1 | 7.2e-12 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Lymph | MS-1 | 2.6e-11 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Brain | rep_4 | 7.2e-54 |
| Nmnat2 | GOBP_Nucleoside_Phosphate_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 2.4e-07 |
| Nmnat2 | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-08 |
| Nmnat2 | GOBP_Organophosphate_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 3.2e-11 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Biosynthetic_Process | Mouse | Brain | HP_adpolb_rep1 | 1.8e-07 |
| Nmnat2 | GOBP_Pyridine_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_adpolb_rep1 | 1.9e-07 |
| Nmnat2 | GOBP_Nad_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 3.5e-07 |
| Nmnat2 | GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 6.9e-09 |
| Nmnat2 | GOBP_Organophosphate_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 7.1e-09 |
| Nmnat2 | GOBP_Small_Molecule_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 2.0e-09 |
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Nmnat2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Nmnat2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Nmnat2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Nmnat2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Nmnat2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Nmnat2 | C0008925 | Cleft Palate | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0014804 | Erythromelalgia | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0020255 | Hydrocephalus | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0020305 | Hydrops Fetalis | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0025990 | Micrognathism | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0152025 | Polyneuropathy | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0206620 | Lymphangioma, Cystic | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0266470 | Cerebellar Hypoplasia | 2 | GENOMICS_ENGLAND |
| Nmnat2 | C0270254 | Hydrops of placenta | 2 | GENOMICS_ENGLAND |
