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Spatial pattern gene: Zfp521 (spascer ID:225207) |
Gene summary for Zfp521 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Zfp521 | Gene ID | 225207 |
| Gene name | zinc finger protein 521 |
| Synonyms | B930086A16Rik|Evi3|Znf521 |
| Cytomap | 18 A1|18 7.68 cM |
| Type of gene | protein-coding |
| Description | zinc finger protein 521ecotropic viral integration site 3 protein |
| Modification date | 20220424 |
| UniProtAcc | Q6KAS7 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Zfp521 | GO:0005634 | nucleus | 21873635 | Component |
| Zfp521 | GO:0010468 | regulation of gene expression | 21873635 | Process |
| Zfp521 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 21873635 | Process |
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Spatial pattern events for Zfp521 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Zfp521 | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Zfp521 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Zfp521 | Mouse | Brain | S3 | 34413515 | 2.96e-15 |
| Zfp521 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Zfp521 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Zfp521 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Zfp521 | Mouse | Brain | 09A | 32637622 | 7.11e-06 |
| Zfp521 | Mouse | Brain | 26A | 32637622 | 3.89e-09 |
| Zfp521 | Mouse | Brain | 27A | 32637622 | 3.99e-07 |
| Zfp521 | Mouse | Brain | 27B | 32637622 | 9.09e-06 |
| Zfp521 | Mouse | Brain | 29A | 32637622 | 1.52e-07 |
| Zfp521 | Mouse | Brain | rep_1 | 35141374 | 6.62e-14 |
| Zfp521 | Mouse | Brain | rep_2 | 35141374 | 2.21e-12 |
| Zfp521 | Mouse | Brain | rep_3 | 35141374 | 1.88e-13 |
| Zfp521 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Zfp521 | Mouse | Brain | rep_5 | 35141374 | 1.43e-11 |
| Zfp521 | Mouse | Brain | rep_6 | 35141374 | 5.96e-15 |
| Zfp521 | Mouse | Embryo | 2G | 34210887 | 3.28e-06 |
| Zfp521 | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Zfp521 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Zfp521 | Mouse | Brain | rep_1 | 35027729 | 7.01e-11 |
| Zfp521 | Mouse | Brain | rep_3 | 35027729 | 2.38e-15 |
| Zfp521 | Mouse | Brain | rep_4 | 35027729 | 1.76e-14 |
| Zfp521 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Zfp521 | Mouse | Testicle | rep_3 | 34731600 | 2.47e-14 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Zfp521 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Spinal cord | L7CN45_C1 | 5.2e-07 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Spinal cord | L7CN45_C1 | 8.9e-09 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Brain | rep_1 | 6.4e-19 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Brain | rep_1 | 8.7e-25 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Brain | rep_1 | 4.8e-33 |
| Zfp521 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_1 | 2.5e-12 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | rep_1 | 1.6e-17 |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Brain | rep_3 | 8.8e-182 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Embryo | rep_14 | 4.6e-10 |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Embryo | rep_1 | 6.8e-22 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Embryo | rep_1 | 8.2e-08 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Embryo | rep_1 | 4.0e-191 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Embryo | rep_3 | 2.1e-193 |
| Zfp521 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_3 | 0.0e+00 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Embryo | rep_3 | 0.0e+00 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Kidney | Nep | 4.6e-22 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Kidney | Nep | 8.3e-23 |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Kidney | rep_2 | 1.1e-65 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Kidney | rep_2 | 2.4e-78 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Kidney | rep_2 | 3.9e-32 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Kidney | rep_2 | 9.6e-64 |
| Zfp521 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 4.5e-10 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Kidney | rep_2 | 8.3e-40 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Liver | CN16-D2 | 5.1e-07 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Liver | rep_16 | 3.1e-10 |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Lymph | MS-1 | 2.1e-11 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Lymph | MS-1 | 4.1e-08 |
| Zfp521 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Lymph | MS-1 | 1.7e-12 |
| Zfp521 | GOBP_Cell_Fate_Commitment | Mouse | Brain | HP_ad_rep7 | 1.5e-09 |
| Zfp521 | GOBP_Neurogenesis | Mouse | Brain | HP_ad_rep7 | 3.9e-07 |
| Zfp521 | GOBP_Neuron_Differentiation | Mouse | Brain | HP_ad_rep7 | 3.9e-07 |
| Zfp521 | GOBP_Neuron_Fate_Commitment | Mouse | Brain | HP_ad_rep7 | 3.2e-12 |
| Zfp521 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-11 |
| Zfp521 | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | HP_ad_rep7 | 7.3e-11 |
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Zfp521 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Zfp521 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Zfp521 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Zfp521 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Zfp521 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
