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Spatial pattern gene: Tmem63b (spascer ID:224807) |
Gene summary for Tmem63b |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Tmem63b | Gene ID | 224807 |
| Gene name | transmembrane protein 63b |
| Synonyms | BC026370 |
| Cytomap | 17|17 C |
| Type of gene | protein-coding |
| Description | CSC1-like protein 2 |
| Modification date | 20220424 |
| UniProtAcc | Q3TWI9 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Tmem63b | GO:0005227 | calcium activated cation channel activity | 21873635 | Function |
| Tmem63b | GO:0005886 | plasma membrane | 21873635 | Component |
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Spatial pattern events for Tmem63b |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Tmem63b | Mouse | Brain | S1 | 34413515 | 6.21e-06 |
| Tmem63b | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Tmem63b | Mouse | Brain | S4 | 34413515 | 9.14e-11 |
| Tmem63b | Mouse | Brain | S7 | 34413515 | 1.77e-07 |
| Tmem63b | Mouse | Brain | rep_1 | 35141374 | 5.86e-08 |
| Tmem63b | Mouse | Brain | rep_2 | 35141374 | 2.07e-12 |
| Tmem63b | Mouse | Brain | rep_4 | 35141374 | 1.05e-10 |
| Tmem63b | Mouse | Brain | rep_6 | 35141374 | 1.26e-13 |
| Tmem63b | Mouse | Embryo | 4E | 34210887 | 5.18e-09 |
| Tmem63b | Mouse | Kidney | IRI | 34003797 | 5.11e-06 |
| Tmem63b | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Tmem63b | Mouse | Brain | rep_1 | 35027729 | 4.80e-06 |
| Tmem63b | Mouse | Brain | rep_2 | 35027729 | 2.83e-15 |
| Tmem63b | Mouse | Brain | rep_3 | 35027729 | 2.38e-15 |
| Tmem63b | Mouse | Brain | rep_4 | 35027729 | 8.21e-08 |
| Tmem63b | Mouse | Brain | rep_5 | 35027729 | 1.43e-10 |
| Tmem63b | Mouse | Intestine | rep_4 | 35149721 | 2.06e-06 |
| Tmem63b | Mouse | Brain | rep_1 | 35210624 | 2.74e-11 |
| Tmem63b | Mouse | Brain | rep_3 | 35210624 | 2.91e-13 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_IRI_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Tmem63b envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Tmem63b | GOBP_Cation_Transport | Mouse | Spinal cord | CN94_E1 | 5.8e-06 |
| Tmem63b | GOBP_Cation_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 1.3e-08 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Tmem63b | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | rep_1 | 4.4e-30 |
| Tmem63b | GOBP_Cation_Transport | Mouse | Brain | rep_1 | 1.5e-22 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Brain | rep_1 | 3.1e-23 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Kidney | Nep | 4.2e-26 |
| Tmem63b | GOBP_Cation_Transmembrane_Transport | Mouse | Kidney | rep_2 | 7.3e-17 |
| Tmem63b | GOBP_Cation_Transport | Mouse | Kidney | rep_2 | 5.9e-23 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.7e-23 |
| Tmem63b | GOBP_Cation_Transmembrane_Transport | Mouse | Liver | rep_15 | 8.9e-14 |
| Tmem63b | GOBP_Cation_Transport | Mouse | Liver | rep_16 | 1.2e-18 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Liver | rep_16 | 1.4e-13 |
| Tmem63b | GOBP_Cation_Transport | Mouse | Brain | HP_ad_rep7 | 7.5e-07 |
| Tmem63b | GOBP_Transmembrane_Transport | Mouse | Brain | HP_ad_rep7 | 3.4e-07 |
| Tmem63b | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | HP_polb_rep9 | 1.4e-07 |
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Tmem63b function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Tmem63b function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Tmem63b envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Tmem63b |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Tmem63b |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
