Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Clic5 (spascer ID:224796)

Gene summary for Clic5

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Clic5
	Gene ID	224796
	Gene name	chloride intracellular channel 5
	Synonyms	5730531E12Rik\|B330005L24\|Gm322\|jbg\|nmf318
	Cytomap	17\|17 B3
	Type of gene	protein-coding
	Description	chloride intracellular channel protein 5
	Modification date	20220424
	UniProtAcc	Q8BXK9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Clic5	GO:0005254	chloride channel activity	21873635	Function
Clic5	GO:0005737	cytoplasm	21873635	Component
Clic5	GO:0006821	chloride transport	21873635	Process
Clic5	GO:0016020	membrane	21873635	Component

Top

Spatial pattern events for Clic5

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Clic5	Mouse	Kidney	IRI	34003797	8.51e-10
Clic5	Mouse	Kidney	rep_1	34853151	2.42e-15
Clic5	Mouse	Kidney	rep_3	34853151	1.42e-08
Clic5	Mouse	Kidney	rep_4	34853151	2.55e-07
Clic5	Mouse	Kidney	rep_5	34853151	5.45e-15
Clic5	Mouse	Intestine	rep_1	35149721	6.08e-15
Clic5	Mouse	Intestine	rep_2	35149721	5.49e-15
Clic5	Mouse	Intestine	rep_3	35149721	3.25e-15
Clic5	Mouse	Intestine	rep_4	35149721	2.30e-15
Clic5	Mouse	Lymph	A1	0	2.07e-06
Clic5	Mouse	Lymph	B1	0	3.66e-15
Clic5	Mouse	Lung	rep_1	35290801	4.52e-15
Clic5	Mouse	Lung	rep_2	35290801	7.23e-15
Clic5	Mouse	Lung	rep_3	35290801	5.26e-15
Clic5	Mouse	Lung	rep_4	35290801	3.04e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

Top

Spatial pattern pathway has Clic5 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Spinal cord	CN94_E1	4.9e-07
Clic5	GOBP_Regulation_Of_Transport	Mouse	Spinal cord	CN94_E1	5.3e-07
Clic5	GOBP_Reproduction	Mouse	Spinal cord	CN94_E1	7.8e-08
Clic5	GOBP_Chloride_Transport	Mouse	Spinal cord	L7bCN02_E1	9.0e-07
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Spinal cord	L7bCN02_E1	1.9e-06
Clic5	GOBP_Nervous_System_Process	Mouse	Spinal cord	L7bCN02_E1	2.5e-06
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.3e-07
Clic5	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	6.6e-07
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Clic5	GOBP_Regulation_Of_Ion_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Clic5	GOBP_Sensory_Perception	Mouse	Spinal cord	L7CN45_C1	5.0e-07
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Spinal cord	L7CN45_C1	2.3e-08
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Spinal cord	L7CN45_C1	2.4e-07
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.4e-07
Clic5	GOBP_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Spinal cord	L7CN97_E2	6.0e-06
Clic5	GOBP_Chloride_Transport	Mouse	Brain	rep_27	1.4e-06
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Brain	rep_27	4.8e-07
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Brain	rep_27	8.3e-05
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Brain	rep_71	5.8e-05
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Brain	rep_1	3.1e-18
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Brain	rep_1	6.0e-09
Clic5	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Brain	rep_1	8.6e-24
Clic5	GOBP_Nervous_System_Process	Mouse	Brain	rep_1	1.6e-36
Clic5	GOBP_Regulation_Of_Ion_Transport	Mouse	Brain	rep_1	8.9e-34
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Brain	rep_1	1.4e-17
Clic5	GOBP_Regulation_Of_Transport	Mouse	Brain	rep_1	3.9e-15
Clic5	GOBP_Transmembrane_Transport	Mouse	Brain	rep_1	3.1e-23
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Brain	rep_3	3.0e-77
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.6e-109
Clic5	GOBP_Chloride_Transport	Mouse	Brain	rep_3	1.6e-103
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Brain	rep_3	1.3e-146
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Clic5	GOBP_Reproduction	Mouse	Brain	rep_3	3.4e-125
Clic5	GOBP_Sensory_Perception	Mouse	Brain	rep_3	2.9e-57
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Brain	rep_3	1.1e-51
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Brain	rep_3	1.7e-132
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	rep_3	1.4e-160
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Brain	rep_7	1.9e-35
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Embryo	rep_14	5.1e-40
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.7e-13
Clic5	GOBP_Chloride_Transport	Mouse	Embryo	rep_14	6.5e-57
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Embryo	rep_14	9.3e-30
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Embryo	rep_14	3.5e-25
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Embryo	rep_14	5.9e-15
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Embryo	rep_14	3.8e-13
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Clic5	GOBP_Sensory_Perception	Mouse	Embryo	rep_14	5.0e-07
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Embryo	rep_14	1.6e-53
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Embryo	rep_14	5.8e-13
Clic5	GOBP_Nervous_System_Process	Mouse	Embryo	rep_1	1.4e-08
Clic5	GOBP_Sensory_Perception	Mouse	Embryo	rep_3	0.0e+00
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Embryo	rep_3	8.3e-301
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Embryo	rep_5	1.1e-16
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Kidney	Nep	4.2e-26
Clic5	GOBP_Regulation_Of_Transport	Mouse	Kidney	Nep	2.6e-47
Clic5	GOBP_Transmembrane_Transport	Mouse	Kidney	Nep	4.2e-26
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Kidney	rep_2	1.0e-56
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-36
Clic5	GOBP_Chloride_Transport	Mouse	Kidney	rep_2	5.7e-79
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-24
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Kidney	rep_2	1.7e-139
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Kidney	rep_2	1.4e-96
Clic5	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Kidney	rep_2	2.4e-15
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Kidney	rep_2	8.0e-57
Clic5	GOBP_Nervous_System_Process	Mouse	Kidney	rep_2	1.9e-90
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Clic5	GOBP_Regulation_Of_Ion_Transport	Mouse	Kidney	rep_2	5.5e-106
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Kidney	rep_2	2.0e-115
Clic5	GOBP_Regulation_Of_Transport	Mouse	Kidney	rep_2	2.4e-58
Clic5	GOBP_Reproduction	Mouse	Kidney	rep_2	9.0e-46
Clic5	GOBP_Sensory_Perception	Mouse	Kidney	rep_2	1.4e-94
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Kidney	rep_2	1.2e-132
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Kidney	rep_2	3.0e-69
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Kidney	rep_2	8.6e-17
Clic5	GOBP_Transmembrane_Transport	Mouse	Kidney	rep_2	2.7e-23
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Liver	CN16-D1	5.6e-07
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Liver	CN73-C1	9.5e-07
Clic5	GOBP_Nervous_System_Process	Mouse	Liver	CN73-C1	1.7e-08
Clic5	GOBP_Regulation_Of_Transport	Mouse	Liver	CN73-C1	1.8e-07
Clic5	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Liver	rep_15	2.4e-07
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Liver	rep_16	4.6e-08
Clic5	GOBP_Transmembrane_Transport	Mouse	Liver	rep_16	1.4e-13
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Intestine	rep_2	7.1e-07
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Lymph	MS-1	7.5e-13
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.7e-15
Clic5	GOBP_Chloride_Transport	Mouse	Lymph	MS-1	2.4e-10
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Lymph	MS-1	2.3e-10
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Lymph	MS-1	2.1e-13
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Lymph	MS-1	4.6e-12
Clic5	GOBP_Nervous_System_Process	Mouse	Lymph	MS-1	1.4e-08
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Clic5	GOBP_Regulation_Of_Ion_Transport	Mouse	Lymph	MS-1	1.5e-09
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Lymph	MS-1	3.3e-13
Clic5	GOBP_Regulation_Of_Transport	Mouse	Lymph	MS-1	1.4e-12
Clic5	GOBP_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Clic5	GOBP_Sensory_Perception	Mouse	Lymph	MS-1	5.2e-11
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Lymph	MS-1	3.2e-08
Clic5	GOBP_Sensory_Perception_Of_Mechanical_Stimulus	Mouse	Lymph	MS-1	9.0e-11
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Lymph	MS-1	7.8e-10
Clic5	GOBP_Reproduction	Mouse	Lung	rep_1	9.6e-12
Clic5	GOBP_Chloride_Transport	Mouse	Brain	rep_4	2.5e-17
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Brain	rep_4	4.7e-42
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Brain	rep_4	2.7e-08
Clic5	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Clic5	GOBP_Chloride_Transport	Mouse	Brain	HP_ad_rep7	1.6e-10
Clic5	GOBP_Inorganic_Anion_Transmembrane_Transport	Mouse	Brain	HP_ad_rep7	2.4e-11
Clic5	GOBP_Inorganic_Anion_Transport	Mouse	Brain	HP_ad_rep7	3.8e-14
Clic5	GOBP_Nervous_System_Process	Mouse	Brain	HP_ad_rep7	7.0e-10
Clic5	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Clic5	GOBP_Regulation_Of_Transmembrane_Transport	Mouse	Brain	HP_ad_rep7	1.5e-07
Clic5	GOBP_Regulation_Of_Transport	Mouse	Brain	HP_ad_rep7	9.2e-09
Clic5	GOBP_Reproduction	Mouse	Brain	HP_ad_rep7	7.9e-09
Clic5	GOBP_Transmembrane_Transport	Mouse	Brain	HP_ad_rep7	3.4e-07
Clic5	GOBP_Multi_Multicellular_Organism_Process	Mouse	Brain	HP_adpolb_rep1	5.4e-12
Clic5	GOBP_Anion_Transmembrane_Transport	Mouse	Brain	HP_polb_rep9	6.5e-17
Clic5	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.3e-15
Clic5	GOBP_Glutathione_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.6e-11
Clic5	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Brain	HP_polb_rep9	1.1e-07
Clic5	GOBP_Sensory_Perception	Mouse	Brain	HP_polb_rep9	1.2e-09
Clic5	GOBP_Sensory_Perception_Of_Light_Stimulus	Mouse	Brain	HP_polb_rep9	5.5e-10
Clic5	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-08

Top

Clic5 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Clic5 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Clic5 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Clic5

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Clic5

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Clic5	C1846647	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	3	CLINGEN
Clic5	C4015050	DEAFNESS, AUTOSOMAL RECESSIVE 103	1	CTD_human;GENOMICS_ENGLAND