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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Fmnl3 (spascer ID:22379)

Gene summary for Fmnl3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Fmnl3
	Gene ID	22379
	Gene name	formin-like 3
	Synonyms	2700073B04Rik\|FBP11\|Wbp3\|mKIAA2014
	Cytomap	15\|15 F1
	Type of gene	protein-coding
	Description	formin-like protein 3WW domain binding protein 3formin-like 3 protein
	Modification date	20220424
	UniProtAcc	Q6ZPF4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Fmnl3	GO:0005829	cytosol	21873635	Component
Fmnl3	GO:0008360	regulation of cell shape	21873635	Process
Fmnl3	GO:0016477	cell migration	21873635	Process
Fmnl3	GO:0030866	cortical actin cytoskeleton organization	21873635	Process
Fmnl3	GO:0051015	actin filament binding	21873635	Function

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Spatial pattern events for Fmnl3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Fmnl3	Mouse	Embryo	rep_2	33188776	9.12e-08
Fmnl3	Mouse	Embryo	rep_13	33188776	2.07e-06
Fmnl3	Mouse	Kidney	CLP	34003797	2.19e-15
Fmnl3	Mouse	Kidney	IRI	34003797	2.29e-15
Fmnl3	Mouse	Kidney	Sham	34003797	2.58e-15
Fmnl3	Mouse	Kidney	rep_1	34853151	2.42e-15
Fmnl3	Mouse	Kidney	rep_3	34853151	2.94e-15
Fmnl3	Mouse	Kidney	rep_4	34853151	6.82e-15
Fmnl3	Mouse	Kidney	rep_5	34853151	1.76e-08
Fmnl3	Mouse	Testicle	rep_4	34731600	1.67e-14
Fmnl3	Mouse	Lung	rep_1	35290801	6.13e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has Fmnl3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Fmnl3	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	9.8e-08
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	6.0e-09
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Fmnl3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Spinal cord	L7CN45_C1	2.7e-06
Fmnl3	GOBP_Tube_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Fmnl3	GOBP_Vasculature_Development	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Fmnl3	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Fmnl3	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Fmnl3	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_27	1.4e-06
Fmnl3	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Brain	rep_1	3.9e-09
Fmnl3	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	rep_3	5.3e-58
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	rep_3	7.4e-87
Fmnl3	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Brain	rep_3	1.3e-81
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-64
Fmnl3	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	rep_3	3.2e-44
Fmnl3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Brain	rep_3	5.0e-45
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	rep_3	2.1e-19
Fmnl3	GOBP_Tube_Development	Mouse	Brain	rep_3	9.0e-136
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Brain	rep_3	4.7e-120
Fmnl3	GOBP_Vasculature_Development	Mouse	Brain	rep_3	2.6e-82
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Embryo	rep_6	1.6e-12
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Embryo	rep_14	1.8e-13
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Embryo	rep_14	1.3e-18
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Embryo	rep_14	5.1e-07
Fmnl3	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Fmnl3	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Embryo	rep_6	3.8e-28
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Embryo	rep_6	1.6e-86
Fmnl3	GOBP_Vasculature_Development	Mouse	Embryo	rep_6	1.9e-41
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	Nep	1.3e-32
Fmnl3	GOBP_Tube_Development	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Vasculature_Development	Mouse	Kidney	Nep	5.6e-37
Fmnl3	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	rep_2	5.6e-148
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	rep_2	3.2e-114
Fmnl3	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Kidney	rep_2	6.7e-139
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Kidney	rep_2	2.7e-87
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-78
Fmnl3	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Fmnl3	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	rep_2	1.3e-133
Fmnl3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.9e-85
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Kidney	rep_2	3.0e-66
Fmnl3	GOBP_Tube_Development	Mouse	Kidney	rep_2	1.2e-129
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Kidney	rep_2	2.1e-134
Fmnl3	GOBP_Vasculature_Development	Mouse	Kidney	rep_2	2.3e-129
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Liver	rep_15	1.3e-18
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Liver	rep_15	9.0e-09
Fmnl3	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Fmnl3	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Fmnl3	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Lymph	MS-1	6.4e-13
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Lymph	MS-1	3.6e-10
Fmnl3	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Lymph	MS-1	1.6e-11
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-12
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.5e-14
Fmnl3	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Fmnl3	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Lymph	MS-1	2.4e-16
Fmnl3	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Lymph	MS-1	2.2e-13
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Lymph	MS-1	5.2e-14
Fmnl3	GOBP_Tube_Development	Mouse	Lymph	MS-1	4.6e-09
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Lymph	MS-1	9.1e-10
Fmnl3	GOBP_Vasculature_Development	Mouse	Lymph	MS-1	3.0e-12
Fmnl3	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Fmnl3	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Fmnl3	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	7.1e-11
Fmnl3	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Fmnl3	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Fmnl3	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	HP_ad_rep7	3.3e-08
Fmnl3	GOBP_Tube_Development	Mouse	Brain	HP_ad_rep7	2.0e-08
Fmnl3	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Fmnl3	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	HP_polb_rep9	6.3e-08
Fmnl3	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.0e-11
Fmnl3	GOBP_Circulatory_System_Development	Mouse	Brain	HP_polb_rep9	3.1e-09
Fmnl3	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.2e-10
Fmnl3	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	HP_polb_rep9	2.9e-08
Fmnl3	GOBP_Tube_Morphogenesis	Mouse	Brain	HP_polb_rep9	4.0e-10
Fmnl3	GOBP_Vasculature_Development	Mouse	Brain	HP_polb_rep9	3.4e-10

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Fmnl3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Fmnl3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Fmnl3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Fmnl3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Fmnl3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source