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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mrtfa (spascer ID:223701)

Gene summary for Mrtfa

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mrtfa
	Gene ID	223701
	Gene name	myocardin related transcription factor A
	Synonyms	AMKL\|Bsac\|Mal\|Mkl1\|Mrtf-A
	Cytomap	15\|15 E1
	Type of gene	protein-coding
	Description	myocardin-related transcription factor AMKL (megakaryoblastic leukemia)/myocardin-like 1MKL/myocardin-like protein 1basic SAP and coiled-coil domainsbasic SAP coiled-coil transcription activatormegakaryoblastic leukemia (translocation) 1 homologmega
	Modification date	20220424
	UniProtAcc	Q8K4J6

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mrtfa	GO:0003713	transcription coactivator activity	21873635	Function
Mrtfa	GO:0005634	nucleus	21873635	Component
Mrtfa	GO:0045944	positive regulation of transcription by RNA polymerase II	21873635	Process
Mrtfa	GO:0051145	smooth muscle cell differentiation	21873635	Process

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Spatial pattern events for Mrtfa

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mrtfa	Mouse	Brain	S1	34413515	2.07e-15
Mrtfa	Mouse	Brain	S2	34413515	1.56e-15
Mrtfa	Mouse	Brain	S3	34413515	2.96e-15
Mrtfa	Mouse	Brain	S4	34413515	1.37e-15
Mrtfa	Mouse	Brain	S6	34413515	1.46e-15
Mrtfa	Mouse	Brain	S7	34413515	1.55e-15
Mrtfa	Mouse	Brain	rep_2	35141374	2.41e-08
Mrtfa	Mouse	Brain	rep_3	35141374	3.00e-15
Mrtfa	Mouse	Brain	rep_4	35141374	2.84e-15
Mrtfa	Mouse	Brain	rep_5	35141374	1.93e-10
Mrtfa	Mouse	Brain	rep_6	35141374	1.60e-06
Mrtfa	Mouse	Kidney	rep_1	34853151	4.13e-15
Mrtfa	Mouse	Kidney	rep_5	34853151	2.11e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_1_H&E
Kidney_rep_5_H&E

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Spatial pattern pathway has Mrtfa envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mrtfa	GOBP_Muscle_Structure_Development	Mouse	Spinal cord	CN94_E1	7.5e-07
Mrtfa	GOBP_Response_To_Wounding	Mouse	Spinal cord	CN94_E1	4.7e-06
Mrtfa	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Mrtfa	GOBP_Epiboly	Mouse	Spinal cord	L7bCN02_E1	3.0e-08
Mrtfa	GOBP_Epithelium_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Spinal cord	L7CN45_C1	2.9e-06
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Mrtfa	GOBP_Tissue_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Mrtfa	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Mrtfa	GOBP_Wound_Healing	Mouse	Spinal cord	L7CN47_C1	8.4e-07
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Spinal cord	L7CN60_D1	1.8e-06
Mrtfa	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Mrtfa	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Brain	rep_27	2.7e-05
Mrtfa	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Mrtfa	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Brain	rep_1	2.6e-13
Mrtfa	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Brain	rep_1	7.0e-16
Mrtfa	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Mrtfa	GOBP_Epiboly	Mouse	Brain	rep_3	5.4e-74
Mrtfa	GOBP_Epithelium_Development	Mouse	Brain	rep_3	8.3e-102
Mrtfa	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Brain	rep_3	2.4e-79
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	rep_3	2.2e-135
Mrtfa	GOBP_Muscle_Structure_Development	Mouse	Brain	rep_3	3.3e-77
Mrtfa	GOBP_Response_To_Wounding	Mouse	Brain	rep_3	6.2e-112
Mrtfa	GOBP_Tissue_Morphogenesis	Mouse	Brain	rep_3	4.8e-136
Mrtfa	GOBP_Wound_Healing	Mouse	Brain	rep_3	6.2e-109
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Embryo	rep_6	1.6e-07
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Embryo	rep_6	2.1e-10
Mrtfa	GOBP_Epiboly	Mouse	Embryo	rep_14	2.5e-77
Mrtfa	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Mrtfa	GOBP_Epithelium_Development	Mouse	Embryo	rep_1	1.7e-09
Mrtfa	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Embryo	rep_3	2.4e-159
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Embryo	rep_3	2.1e-14
Mrtfa	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Mrtfa	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Mrtfa	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Mrtfa	GOBP_Response_To_Wounding	Mouse	Kidney	Nep	1.6e-16
Mrtfa	GOBP_Wound_Healing	Mouse	Kidney	Nep	1.6e-16
Mrtfa	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Mrtfa	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Mrtfa	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Mrtfa	GOBP_Epithelium_Development	Mouse	Kidney	rep_2	3.5e-92
Mrtfa	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Kidney	rep_2	8.3e-27
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Kidney	rep_2	4.1e-93
Mrtfa	GOBP_Muscle_Structure_Development	Mouse	Kidney	rep_2	2.7e-36
Mrtfa	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Mrtfa	GOBP_Response_To_Wounding	Mouse	Kidney	rep_2	2.1e-60
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Kidney	rep_2	1.7e-49
Mrtfa	GOBP_Tissue_Morphogenesis	Mouse	Kidney	rep_2	2.3e-21
Mrtfa	GOBP_Wound_Healing	Mouse	Kidney	rep_2	6.5e-45
Mrtfa	GOBP_Epiboly	Mouse	Liver	CN16-E1	6.7e-08
Mrtfa	GOBP_Response_To_Wounding	Mouse	Liver	CN73-C1	1.1e-07
Mrtfa	GOBP_Wound_Healing	Mouse	Liver	CN73-C1	1.1e-08
Mrtfa	GOBP_Epiboly	Mouse	Liver	rep_16	1.5e-08
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Liver	rep_16	5.4e-08
Mrtfa	GOBP_Response_To_Wounding	Mouse	Liver	rep_16	1.3e-13
Mrtfa	GOBP_Wound_Healing	Mouse	Liver	rep_16	3.5e-11
Mrtfa	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Mrtfa	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Mrtfa	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Mrtfa	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Mrtfa	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Mrtfa	GOBP_Epiboly	Mouse	Lymph	MS-1	7.3e-07
Mrtfa	GOBP_Epithelium_Development	Mouse	Lymph	MS-1	8.5e-09
Mrtfa	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Lymph	MS-1	4.1e-10
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Lymph	MS-1	1.8e-07
Mrtfa	GOBP_Muscle_Structure_Development	Mouse	Lymph	MS-1	3.8e-09
Mrtfa	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Lymph	MS-1	1.4e-09
Mrtfa	GOBP_Tissue_Morphogenesis	Mouse	Lymph	MS-1	1.4e-12
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Lymph	PBS	3.6e-07
Mrtfa	GOBP_Smooth_Muscle_Cell_Differentiation	Mouse	Brain	HP_ad_rep2	3.5e-07
Mrtfa	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Mrtfa	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Mrtfa	GOBP_Epiboly	Mouse	Brain	HP_ad_rep7	2.1e-08
Mrtfa	GOBP_Epithelium_Development	Mouse	Brain	HP_ad_rep7	2.8e-08
Mrtfa	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	HP_ad_rep7	8.4e-09
Mrtfa	GOBP_Muscle_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	5.5e-07
Mrtfa	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Mrtfa	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Mrtfa	GOBP_Response_To_Wounding	Mouse	Brain	HP_ad_rep7	4.3e-07
Mrtfa	GOBP_Morphogenesis_Of_An_Epithelial_Sheet	Mouse	Brain	HP_adpolb_rep5	4.7e-07
Mrtfa	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Mrtfa	GOBP_Tissue_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.2e-10

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Mrtfa function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mrtfa function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mrtfa envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mrtfa

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mrtfa

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source