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Spatial pattern gene: Nipal2 (spascer ID:223473) |
Gene summary for Nipal2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Nipal2 | Gene ID | 223473 |
| Gene name | NIPA-like domain containing 2 |
| Synonyms | 9330161F08Rik|Npal2 |
| Cytomap | 15|15 B3.1 |
| Type of gene | protein-coding |
| Description | NIPA-like protein 2 |
| Modification date | 20220424 |
| UniProtAcc | Q91WC7 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Nipal2 | GO:0015693 | magnesium ion transport | 21873635 | Process |
| Nipal2 | GO:0016020 | membrane | 21873635 | Component |
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Spatial pattern events for Nipal2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Nipal2 | Mouse | Brain | S1 | 34413515 | 3.73e-15 |
| Nipal2 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Nipal2 | Mouse | Brain | S3 | 34413515 | 3.51e-12 |
| Nipal2 | Mouse | Brain | S4 | 34413515 | 2.48e-10 |
| Nipal2 | Mouse | Brain | S6 | 34413515 | 5.07e-15 |
| Nipal2 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Nipal2 | Mouse | Kidney | rep_5 | 34853151 | 2.74e-09 |
| Nipal2 | Mouse | Brain | rep_1 | 33469025 | 5.87e-09 |
| Nipal2 | Mouse | Brain | rep_1 | 35027729 | 2.13e-06 |
| Nipal2 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Nipal2 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Nipal2 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Nipal2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Spinal cord | CN93_D2 | 6.5e-06 |
| Nipal2 | GOBP_Cation_Transport | Mouse | Spinal cord | CN94_E1 | 5.8e-06 |
| Nipal2 | GOBP_Cation_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 1.3e-08 |
| Nipal2 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 6.6e-07 |
| Nipal2 | GOBP_Metal_Ion_Transport | Mouse | Spinal cord | L7CN45_C1 | 4.4e-08 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Nipal2 | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | rep_1 | 4.4e-30 |
| Nipal2 | GOBP_Cation_Transport | Mouse | Brain | rep_1 | 1.5e-22 |
| Nipal2 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Brain | rep_1 | 8.6e-24 |
| Nipal2 | GOBP_Metal_Ion_Transport | Mouse | Brain | rep_1 | 5.1e-10 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Brain | rep_1 | 3.1e-23 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Brain | rep_3 | 2.0e-88 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Embryo | rep_14 | 1.2e-29 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Kidney | Nep | 4.2e-26 |
| Nipal2 | GOBP_Cation_Transmembrane_Transport | Mouse | Kidney | rep_2 | 7.3e-17 |
| Nipal2 | GOBP_Cation_Transport | Mouse | Kidney | rep_2 | 5.9e-23 |
| Nipal2 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.4e-15 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Kidney | rep_2 | 1.5e-11 |
| Nipal2 | GOBP_Metal_Ion_Transport | Mouse | Kidney | rep_2 | 7.0e-69 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.7e-23 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Liver | CN16-D2 | 8.7e-14 |
| Nipal2 | GOBP_Metal_Ion_Transport | Mouse | Liver | CN73-C1 | 6.4e-08 |
| Nipal2 | GOBP_Cation_Transmembrane_Transport | Mouse | Liver | rep_15 | 8.9e-14 |
| Nipal2 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Liver | rep_15 | 2.4e-07 |
| Nipal2 | GOBP_Cation_Transport | Mouse | Liver | rep_16 | 1.2e-18 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Liver | rep_16 | 1.9e-26 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Liver | rep_16 | 1.4e-13 |
| Nipal2 | GOBP_Metal_Ion_Transport | Mouse | Lymph | MS-1 | 1.4e-09 |
| Nipal2 | GOBP_Cation_Transport | Mouse | Brain | HP_ad_rep7 | 7.5e-07 |
| Nipal2 | GOBP_Magnesium_Ion_Transport | Mouse | Brain | HP_ad_rep7 | 2.0e-10 |
| Nipal2 | GOBP_Transmembrane_Transport | Mouse | Brain | HP_ad_rep7 | 3.4e-07 |
| Nipal2 | GOBP_Cation_Transmembrane_Transport | Mouse | Brain | HP_polb_rep9 | 1.4e-07 |
| Nipal2 | GOBP_Inorganic_Ion_Transmembrane_Transport | Mouse | Brain | HP_polb_rep9 | 1.1e-07 |
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Nipal2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Nipal2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Nipal2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Nipal2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Nipal2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Nipal2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
