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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tln1 (spascer ID:21894)

Gene summary for Tln1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tln1
	Gene ID	21894
	Gene name	talin 1
	Synonyms	Tln
	Cytomap	4\|4 A5
	Type of gene	protein-coding
	Description	talin-1
	Modification date	20220424
	UniProtAcc	P26039

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tln1	GO:0005178	integrin binding	21873635	Function
Tln1	GO:0005886	plasma membrane	21873635	Component
Tln1	GO:0005925	focal adhesion	21873635	Component
Tln1	GO:0098609	cell-cell adhesion	21873635	Process

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Spatial pattern events for Tln1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tln1	Mouse	Brain	S2	34413515	1.57e-13
Tln1	Mouse	Brain	S4	34413515	1.37e-15
Tln1	Mouse	Brain	rep_1	35141374	6.37e-07
Tln1	Mouse	Brain	rep_2	35141374	5.75e-15
Tln1	Mouse	Brain	rep_3	35141374	3.00e-15
Tln1	Mouse	Brain	rep_4	35141374	1.57e-15
Tln1	Mouse	Brain	rep_5	35141374	2.68e-15
Tln1	Mouse	Brain	rep_6	35141374	7.59e-09
Tln1	Mouse	Embryo	1F	34210887	9.33e-06
Tln1	Mouse	Embryo	4E	34210887	1.09e-08
Tln1	Mouse	Embryo	rep_1	33188776	3.00e-07
Tln1	Mouse	Embryo	rep_2	33188776	3.50e-14
Tln1	Mouse	Embryo	rep_3	33188776	1.13e-14
Tln1	Mouse	Embryo	rep_5	33188776	2.15e-14
Tln1	Mouse	Embryo	rep_12	33188776	4.84e-15
Tln1	Mouse	Embryo	rep_13	33188776	4.49e-15
Tln1	Mouse	Embryo	rep_15	33188776	7.42e-06
Tln1	Mouse	Kidney	CLP	34003797	6.11e-07
Tln1	Mouse	Kidney	Sham	34003797	7.83e-15
Tln1	Mouse	Kidney	rep_1	34853151	6.50e-12
Tln1	Mouse	Brain	rep_1	35027729	1.66e-15
Tln1	Mouse	Brain	rep_2	35027729	5.53e-13
Tln1	Mouse	Brain	rep_3	35027729	4.57e-15
Tln1	Mouse	Brain	rep_4	35027729	1.93e-11
Tln1	Mouse	Brain	rep_5	35027729	1.36e-12
Tln1	Mouse	Intestine	rep_2	35149721	1.00e-14
Tln1	Mouse	Intestine	rep_3	35149721	9.60e-15
Tln1	Mouse	Lymph	A1	0	3.29e-15
Tln1	Mouse	Lymph	B1	0	3.66e-15
Tln1	Mouse	Lung	rep_1	35290801	4.74e-14
Tln1	Mouse	Lung	rep_2	35290801	6.88e-11
Tln1	Mouse	Brain	rep_3	35210624	2.91e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has Tln1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tln1	GOBP_Platelet_Degranulation	Mouse	Spinal cord	CN93_D2	4.3e-07
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Spinal cord	CN94_E1	9.1e-06
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Tln1	GOBP_Response_To_Wounding	Mouse	Spinal cord	CN94_E1	4.7e-06
Tln1	GOBP_Integrin_Activation	Mouse	Spinal cord	L7bCN01_D2	7.1e-06
Tln1	GOBP_Cell_Junction_Organization	Mouse	Spinal cord	L7bCN02_E1	4.0e-06
Tln1	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Tln1	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Tln1	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Spinal cord	L7CN45_C1	6.8e-10
Tln1	GOBP_Cell_Cell_Junction_Assembly	Mouse	Spinal cord	L7CN45_C1	3.2e-06
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Spinal cord	L7CN45_C1	7.6e-08
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	9.8e-08
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	6.0e-09
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Spinal cord	L7CN45_C1	5.7e-09
Tln1	GOBP_Platelet_Aggregation	Mouse	Spinal cord	L7CN45_C1	5.9e-07
Tln1	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Spinal cord	L7CN45_C1	9.1e-06
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Spinal cord	L7CN45_C1	5.1e-07
Tln1	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Tln1	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Tln1	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Tln1	GOBP_Platelet_Activation	Mouse	Spinal cord	L7CN47_C1	2.0e-06
Tln1	GOBP_Wound_Healing	Mouse	Spinal cord	L7CN47_C1	8.4e-07
Tln1	GOBP_Cell_Cell_Junction_Organization	Mouse	Spinal cord	L7CN47_D1	8.4e-06
Tln1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	L7CN97_E2	6.8e-06
Tln1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_27	5.8e-05
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_27	1.4e-06
Tln1	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Brain	rep_37	3.1e-05
Tln1	GOBP_Platelet_Degranulation	Mouse	Brain	rep_37	7.2e-06
Tln1	GOBP_Integrin_Activation	Mouse	Brain	rep_41	2.2e-05
Tln1	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Tln1	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Tln1	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Brain	rep_1	1.2e-14
Tln1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_1	1.5e-30
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Brain	rep_1	3.9e-09
Tln1	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Tln1	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Tln1	GOBP_Integrin_Activation	Mouse	Brain	rep_1	3.9e-34
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Brain	rep_1	3.5e-10
Tln1	GOBP_Muscle_Contraction	Mouse	Brain	rep_1	6.0e-18
Tln1	GOBP_Muscle_System_Process	Mouse	Brain	rep_1	8.3e-21
Tln1	GOBP_Platelet_Degranulation	Mouse	Brain	rep_1	1.3e-96
Tln1	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Tln1	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Tln1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	rep_3	1.9e-146
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Brain	rep_3	5.2e-118
Tln1	GOBP_Cell_Cell_Junction_Assembly	Mouse	Brain	rep_3	9.8e-91
Tln1	GOBP_Cell_Cell_Junction_Organization	Mouse	Brain	rep_3	8.4e-79
Tln1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Brain	rep_3	1.3e-07
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	rep_3	1.4e-162
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-64
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Brain	rep_3	3.4e-151
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Brain	rep_3	6.9e-165
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Brain	rep_3	3.9e-131
Tln1	GOBP_Platelet_Activation	Mouse	Brain	rep_3	1.1e-161
Tln1	GOBP_Platelet_Aggregation	Mouse	Brain	rep_3	8.0e-165
Tln1	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	rep_3	1.1e-62
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	rep_3	6.3e-133
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	rep_3	8.7e-153
Tln1	GOBP_Response_To_Wounding	Mouse	Brain	rep_3	6.2e-112
Tln1	GOBP_Wound_Healing	Mouse	Brain	rep_3	6.2e-109
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Embryo	rep_6	4.9e-29
Tln1	GOBP_Cell_Cell_Junction_Assembly	Mouse	Embryo	rep_14	2.0e-07
Tln1	GOBP_Cell_Cell_Junction_Organization	Mouse	Embryo	rep_14	5.8e-15
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_14	8.7e-22
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Embryo	rep_14	1.8e-13
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Embryo	rep_14	1.3e-18
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Embryo	rep_14	2.5e-19
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Embryo	rep_14	8.8e-25
Tln1	GOBP_Integrin_Activation	Mouse	Embryo	rep_14	3.9e-49
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Embryo	rep_14	5.5e-61
Tln1	GOBP_Muscle_Contraction	Mouse	Embryo	rep_14	1.7e-07
Tln1	GOBP_Platelet_Activation	Mouse	Embryo	rep_14	2.4e-18
Tln1	GOBP_Platelet_Aggregation	Mouse	Embryo	rep_14	5.9e-23
Tln1	GOBP_Platelet_Degranulation	Mouse	Embryo	rep_14	1.1e-12
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_14	7.2e-14
Tln1	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Tln1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_2	7.4e-121
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Embryo	rep_3	4.6e-28
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_3	0.0e+00
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Embryo	rep_3	1.7e-305
Tln1	GOBP_Integrin_Activation	Mouse	Embryo	rep_3	5.8e-167
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Embryo	rep_3	1.8e-13
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Embryo	rep_3	2.3e-263
Tln1	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Kidney	Nep	1.6e-16
Tln1	GOBP_Response_To_Wounding	Mouse	Kidney	Nep	1.6e-16
Tln1	GOBP_Wound_Healing	Mouse	Kidney	Nep	1.6e-16
Tln1	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Tln1	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Tln1	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Kidney	rep_2	1.1e-24
Tln1	GOBP_Cell_Cell_Junction_Assembly	Mouse	Kidney	rep_2	9.3e-26
Tln1	GOBP_Cell_Cell_Junction_Organization	Mouse	Kidney	rep_2	9.3e-36
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Kidney	rep_2	5.4e-41
Tln1	GOBP_Cell_Junction_Organization	Mouse	Kidney	rep_2	6.2e-52
Tln1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Kidney	rep_2	5.7e-41
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Kidney	rep_2	2.7e-87
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-78
Tln1	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Kidney	rep_2	5.3e-42
Tln1	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Kidney	rep_2	6.2e-70
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Kidney	rep_2	7.1e-13
Tln1	GOBP_Muscle_Contraction	Mouse	Kidney	rep_2	1.1e-89
Tln1	GOBP_Muscle_System_Process	Mouse	Kidney	rep_2	1.2e-86
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Kidney	rep_2	1.2e-89
Tln1	GOBP_Response_To_Wounding	Mouse	Kidney	rep_2	2.1e-60
Tln1	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Tln1	GOBP_Wound_Healing	Mouse	Kidney	rep_2	6.5e-45
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Liver	CN16-D2	9.7e-09
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Liver	CN16-E1	2.0e-07
Tln1	GOBP_Integrin_Activation	Mouse	Liver	CN65-C1	1.9e-07
Tln1	GOBP_Platelet_Activation	Mouse	Liver	CN73-C1	1.6e-11
Tln1	GOBP_Platelet_Aggregation	Mouse	Liver	CN73-C1	1.2e-09
Tln1	GOBP_Response_To_Wounding	Mouse	Liver	CN73-C1	1.1e-07
Tln1	GOBP_Wound_Healing	Mouse	Liver	CN73-C1	1.1e-08
Tln1	GOBP_Platelet_Degranulation	Mouse	Liver	rep_14	3.1e-12
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Liver	rep_15	1.3e-18
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Liver	rep_15	9.0e-09
Tln1	GOBP_Integrin_Activation	Mouse	Liver	rep_15	1.9e-08
Tln1	GOBP_Muscle_System_Process	Mouse	Liver	rep_15	9.3e-22
Tln1	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Liver	rep_16	1.4e-11
Tln1	GOBP_Cell_Cell_Junction_Assembly	Mouse	Liver	rep_16	5.6e-18
Tln1	GOBP_Cell_Cell_Junction_Organization	Mouse	Liver	rep_16	2.9e-08
Tln1	GOBP_Cell_Junction_Organization	Mouse	Liver	rep_16	1.6e-07
Tln1	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Liver	rep_16	1.1e-24
Tln1	GOBP_Platelet_Aggregation	Mouse	Liver	rep_16	3.6e-14
Tln1	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Liver	rep_16	6.1e-20
Tln1	GOBP_Response_To_Wounding	Mouse	Liver	rep_16	1.3e-13
Tln1	GOBP_Wound_Healing	Mouse	Liver	rep_16	3.5e-11
Tln1	GOBP_Integrin_Activation	Mouse	Brain	rep_1	3.5e-05
Tln1	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Tln1	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Tln1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	4.6e-18
Tln1	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Lymph	MS-1	1.9e-13
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Lymph	MS-1	7.9e-08
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-12
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.5e-14
Tln1	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Tln1	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Tln1	GOBP_Homotypic_Cell_Cell_Adhesion	Mouse	Lymph	MS-1	3.1e-07
Tln1	GOBP_Integrin_Activation	Mouse	Lymph	MS-1	4.8e-15
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	1.5e-10
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Lymph	MS-1	3.1e-09
Tln1	GOBP_Muscle_Contraction	Mouse	Lymph	MS-1	3.4e-09
Tln1	GOBP_Muscle_System_Process	Mouse	Lymph	MS-1	1.6e-08
Tln1	GOBP_Platelet_Aggregation	Mouse	Lymph	MS-1	1.6e-07
Tln1	GOBP_Platelet_Degranulation	Mouse	Lymph	MS-1	8.6e-08
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Lymph	MS-1	1.7e-11
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Lymph	MS-1	2.8e-07
Tln1	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Lymph	PBS	1.2e-07
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Lymph	PBS	2.4e-07
Tln1	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Lung	rep_1	2.9e-07
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Brain	rep_4	6.5e-07
Tln1	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_4	3.7e-07
Tln1	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Tln1	GOBP_Integrin_Activation	Mouse	Brain	rep_4	5.5e-12
Tln1	GOBP_Platelet_Degranulation	Mouse	Brain	rep_4	2.8e-58
Tln1	GOBP_Platelet_Degranulation	Mouse	Brain	HP_ad_rep3	5.8e-07
Tln1	GOBP_Cell_Junction_Assembly	Mouse	Brain	HP_ad_rep7	1.3e-11
Tln1	GOBP_Cell_Junction_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Tln1	GOBP_Cell_Substrate_Junction_Organization	Mouse	Brain	HP_ad_rep7	4.0e-10
Tln1	GOBP_Cortical_Actin_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	7.1e-11
Tln1	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Tln1	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	9.5e-09
Tln1	GOBP_Response_To_Wounding	Mouse	Brain	HP_ad_rep7	4.3e-07
Tln1	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Tln1	GOBP_Integrin_Activation	Mouse	Brain	HP_adpolb_rep1	1.2e-09
Tln1	GOBP_Ire1_Mediated_Unfolded_Protein_Response	Mouse	Brain	HP_adpolb_rep6	1.1e-07
Tln1	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Tln1	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Tln1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_polb_rep9	1.1e-12
Tln1	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Tln1	GOBP_Cell_Cell_Adhesion	Mouse	Brain	HP_polb_rep9	3.6e-11
Tln1	GOBP_Cellular_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	HP_polb_rep9	2.8e-08
Tln1	GOBP_Cortical_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.2e-10
Tln1	GOBP_Endoplasmic_Reticulum_Unfolded_Protein_Response	Mouse	Brain	HP_polb_rep9	2.7e-13
Tln1	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Tln1	GOBP_Muscle_Contraction	Mouse	Brain	HP_polb_rep9	8.1e-07
Tln1	GOBP_Platelet_Activation	Mouse	Brain	HP_polb_rep9	1.1e-07
Tln1	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	HP_polb_rep9	2.9e-10
Tln1	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	HP_polb_rep9	3.5e-12
Tln1	GOBP_Response_To_Topologically_Incorrect_Protein	Mouse	Brain	HP_polb_rep9	5.0e-08

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Tln1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Tln1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
Tln1	Itgal	Tln1_Itgal	Brain	rep_3
Tln1	Itgb1	Tln1_Itgb1	Brain	rep_3
Tln1	Itgb2	Tln1_Itgb2	Brain	rep_3

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Transcription factor for Tln1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Tln1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Tln1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Tln1	C0001787	Osteoporosis, Age-Related	1	CTD_human
Tln1	C0027626	Neoplasm Invasiveness	1	CTD_human
Tln1	C0029456	Osteoporosis	1	CTD_human
Tln1	C0029459	Osteoporosis, Senile	1	CTD_human
Tln1	C0751406	Post-Traumatic Osteoporosis	1	CTD_human