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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Vps41 (spascer ID:218035)

Gene summary for Vps41

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Vps41
	Gene ID	218035
	Gene name	VPS41 HOPS complex subunit
	Synonyms	AI317346\|Vam2\|mVam2
	Cytomap	13 A2\|13 6.75 cM
	Type of gene	protein-coding
	Description	vacuolar protein sorting-associated protein 41 homologVAM2 homologvacuolar protein sorting 41
	Modification date	20220424
	UniProtAcc	Q5KU39

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Vps41	GO:0005770	late endosome	21873635	Component
Vps41	GO:0006623	protein targeting to vacuole	21873635	Process
Vps41	GO:0009267	cellular response to starvation	21873635	Process
Vps41	GO:0016236	macroautophagy	21873635	Process
Vps41	GO:0030897	HOPS complex	21873635	Component
Vps41	GO:0034058	endosomal vesicle fusion	21873635	Process

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Spatial pattern events for Vps41

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Vps41	Mouse	Brain	S1	34413515	1.76e-10
Vps41	Mouse	Brain	S2	34413515	2.85e-15
Vps41	Mouse	Brain	S3	34413515	2.40e-12
Vps41	Mouse	Brain	S4	34413515	2.43e-15
Vps41	Mouse	Brain	S6	34413515	1.46e-15
Vps41	Mouse	Brain	S7	34413515	7.64e-06
Vps41	Mouse	Brain	rep_1	35141374	6.97e-06
Vps41	Mouse	Brain	rep_2	35141374	5.75e-15
Vps41	Mouse	Brain	rep_3	35141374	1.52e-09
Vps41	Mouse	Brain	rep_4	35141374	2.84e-15
Vps41	Mouse	Brain	rep_5	35141374	5.13e-15
Vps41	Mouse	Brain	rep_6	35141374	1.73e-15
Vps41	Mouse	Embryo	rep_4	33188776	1.36e-09
Vps41	Mouse	Embryo	rep_5	33188776	3.86e-14
Vps41	Mouse	Brain	rep_1	33469025	2.37e-15
Vps41	Mouse	Brain	rep_1	35027729	7.00e-10
Vps41	Mouse	Brain	rep_2	35027729	7.38e-13
Vps41	Mouse	Brain	rep_3	35027729	1.32e-15
Vps41	Mouse	Brain	rep_4	35027729	5.87e-15
Vps41	Mouse	Brain	rep_5	35027729	5.00e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Vps41 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Spinal cord	CN94_E1	9.3e-06
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Spinal cord	CN94_E1	5.0e-06
Vps41	GOBP_Lysosomal_Transport	Mouse	Spinal cord	CN94_E1	6.6e-06
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Spinal cord	L7bCN02_E1	1.4e-06
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Vps41	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Vps41	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Vps41	GOBP_Late_Endosome_To_Lysosome_Transport	Mouse	Spinal cord	L7CN45_C1	7.0e-06
Vps41	GOBP_Macroautophagy	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Vps41	GOBP_Membrane_Organization	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Vps41	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Vps41	GOBP_Protein_Localization_To_Organelle	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Spinal cord	L7CN45_C1	5.2e-07
Vps41	GOBP_Protein_Targeting	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Vps41	GOBP_Response_To_Starvation	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Vps41	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Vps41	GOBP_Vacuolar_Transport	Mouse	Spinal cord	L7CN45_C1	5.1e-07
Vps41	GOBP_Vesicle_Organization	Mouse	Spinal cord	L7CN45_C1	7.6e-07
Vps41	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Vps41	GOBP_Membrane_Fusion	Mouse	Spinal cord	L7CN47_C1	4.7e-06
Vps41	GOBP_Organelle_Fusion	Mouse	Spinal cord	L7CN47_C1	2.3e-06
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Spinal cord	L7CN47_C1	4.4e-06
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Spinal cord	L7CN97_E2	3.3e-06
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Brain	rep_27	1.3e-05
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Brain	rep_27	7.5e-08
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Brain	rep_27	4.7e-06
Vps41	GOBP_Response_To_Starvation	Mouse	Brain	rep_27	7.4e-08
Vps41	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Brain	rep_1	9.1e-23
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Brain	rep_1	2.7e-29
Vps41	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Vps41	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Vps41	GOBP_Late_Endosome_To_Lysosome_Transport	Mouse	Brain	rep_1	8.6e-17
Vps41	GOBP_Macroautophagy	Mouse	Brain	rep_1	6.7e-14
Vps41	GOBP_Membrane_Fusion	Mouse	Brain	rep_1	3.8e-47
Vps41	GOBP_Organelle_Fusion	Mouse	Brain	rep_1	1.0e-55
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Brain	rep_1	1.3e-56
Vps41	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Vps41	GOBP_Vesicle_Organization	Mouse	Brain	rep_1	7.9e-37
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Brain	rep_3	1.9e-53
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Brain	rep_3	5.2e-44
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Brain	rep_3	1.1e-148
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Brain	rep_3	1.2e-180
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Brain	rep_3	5.5e-77
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Brain	rep_3	2.7e-132
Vps41	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Vps41	GOBP_Lysosomal_Transport	Mouse	Brain	rep_3	1.6e-81
Vps41	GOBP_Membrane_Organization	Mouse	Brain	rep_3	1.9e-41
Vps41	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Brain	rep_3	1.0e-145
Vps41	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	rep_3	6.3e-172
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Brain	rep_3	5.1e-64
Vps41	GOBP_Protein_Targeting	Mouse	Brain	rep_3	2.9e-187
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Brain	rep_3	1.4e-83
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	rep_3	2.2e-117
Vps41	GOBP_Response_To_Starvation	Mouse	Brain	rep_3	5.8e-139
Vps41	GOBP_Vacuolar_Transport	Mouse	Brain	rep_3	3.9e-136
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Embryo	rep_14	2.6e-25
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Embryo	rep_14	2.1e-30
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Embryo	rep_14	6.3e-13
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Embryo	rep_14	4.9e-07
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Embryo	rep_14	4.4e-11
Vps41	GOBP_Protein_Targeting	Mouse	Embryo	rep_14	6.3e-09
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Embryo	rep_14	4.2e-10
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Embryo	rep_1	2.1e-63
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Embryo	rep_1	1.7e-07
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Embryo	rep_1	8.6e-17
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Vps41	GOBP_Organelle_Fusion	Mouse	Embryo	rep_3	1.8e-198
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Embryo	rep_4	1.1e-39
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Embryo	rep_4	1.2e-08
Vps41	GOBP_Membrane_Fusion	Mouse	Embryo	rep_5	2.5e-16
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Kidney	rep_2	1.6e-13
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Kidney	rep_2	4.8e-18
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Kidney	rep_2	3.2e-89
Vps41	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Kidney	rep_2	3.3e-19
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Kidney	rep_2	9.1e-128
Vps41	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Kidney	rep_2	7.5e-54
Vps41	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Vps41	GOBP_Late_Endosome_To_Lysosome_Transport	Mouse	Kidney	rep_2	6.2e-52
Vps41	GOBP_Lysosomal_Transport	Mouse	Kidney	rep_2	6.1e-84
Vps41	GOBP_Macroautophagy	Mouse	Kidney	rep_2	1.3e-64
Vps41	GOBP_Membrane_Fusion	Mouse	Kidney	rep_2	3.4e-106
Vps41	GOBP_Membrane_Organization	Mouse	Kidney	rep_2	8.5e-74
Vps41	GOBP_Organelle_Fusion	Mouse	Kidney	rep_2	1.4e-95
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Kidney	rep_2	5.0e-66
Vps41	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Kidney	rep_2	1.8e-66
Vps41	GOBP_Protein_Localization_To_Organelle	Mouse	Kidney	rep_2	3.4e-44
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Kidney	rep_2	1.1e-140
Vps41	GOBP_Protein_Targeting	Mouse	Kidney	rep_2	1.7e-40
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Kidney	rep_2	1.3e-130
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Kidney	rep_2	3.8e-52
Vps41	GOBP_Response_To_Starvation	Mouse	Kidney	rep_2	1.3e-11
Vps41	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Vps41	GOBP_Vacuolar_Transport	Mouse	Kidney	rep_2	5.2e-99
Vps41	GOBP_Vesicle_Organization	Mouse	Kidney	rep_2	6.0e-62
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Liver	CN16-D1	2.7e-08
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Liver	CN16-D2	5.1e-18
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Liver	CN16-E1	7.5e-07
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Liver	CN16-E1	1.5e-07
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Liver	rep_15	1.2e-25
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Liver	rep_15	4.3e-11
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Liver	rep_16	6.3e-14
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Liver	rep_16	4.1e-17
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Liver	rep_16	1.1e-15
Vps41	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Liver	rep_16	8.0e-26
Vps41	GOBP_Response_To_Starvation	Mouse	Liver	rep_16	9.4e-25
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Lymph	MS-1	4.4e-13
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Lymph	MS-1	1.6e-14
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Lymph	MS-1	7.4e-11
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Lymph	MS-1	4.5e-15
Vps41	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Lymph	MS-1	3.3e-11
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Lymph	MS-1	6.0e-08
Vps41	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Lymph	MS-1	3.0e-17
Vps41	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Vps41	GOBP_Late_Endosome_To_Lysosome_Transport	Mouse	Lymph	MS-1	3.3e-14
Vps41	GOBP_Lysosomal_Transport	Mouse	Lymph	MS-1	6.7e-08
Vps41	GOBP_Macroautophagy	Mouse	Lymph	MS-1	3.3e-11
Vps41	GOBP_Membrane_Organization	Mouse	Lymph	MS-1	5.8e-20
Vps41	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Lymph	MS-1	3.9e-13
Vps41	GOBP_Protein_Localization_To_Organelle	Mouse	Lymph	MS-1	1.4e-09
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Lymph	MS-1	1.5e-07
Vps41	GOBP_Protein_Targeting	Mouse	Lymph	MS-1	2.1e-09
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Lymph	MS-1	4.4e-08
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Lymph	MS-1	1.1e-12
Vps41	GOBP_Response_To_Starvation	Mouse	Lymph	MS-1	1.7e-10
Vps41	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Vps41	GOBP_Vacuolar_Transport	Mouse	Lymph	MS-1	1.1e-08
Vps41	GOBP_Vesicle_Organization	Mouse	Lymph	MS-1	1.9e-12
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Lymph	PBS	2.5e-09
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Brain	rep_4	7.0e-15
Vps41	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Vps41	GOBP_Organelle_Fusion	Mouse	Brain	rep_4	8.5e-11
Vps41	GOBP_Vesicle_Organization	Mouse	Brain	rep_4	7.9e-08
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Brain	rep_7	1.9e-09
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Brain	rep_7	1.9e-37
Vps41	GOBP_Response_To_Starvation	Mouse	Brain	rep_7	5.6e-09
Vps41	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Vps41	GOBP_Cellular_Response_To_Starvation	Mouse	Brain	HP_ad_rep7	3.0e-14
Vps41	GOBP_Endosomal_Vesicle_Fusion	Mouse	Brain	HP_ad_rep7	5.1e-18
Vps41	GOBP_Endosome_To_Lysosome_Transport	Mouse	Brain	HP_ad_rep7	8.5e-10
Vps41	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Brain	HP_ad_rep7	6.1e-09
Vps41	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Mouse	Brain	HP_ad_rep7	6.0e-10
Vps41	GOBP_Intracellular_Protein_Transport	Mouse	Brain	HP_ad_rep7	3.6e-08
Vps41	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Vps41	GOBP_Late_Endosome_To_Lysosome_Transport	Mouse	Brain	HP_ad_rep7	1.4e-08
Vps41	GOBP_Lysosomal_Transport	Mouse	Brain	HP_ad_rep7	3.3e-09
Vps41	GOBP_Macroautophagy	Mouse	Brain	HP_ad_rep7	1.6e-07
Vps41	GOBP_Process_Utilizing_Autophagic_Mechanism	Mouse	Brain	HP_ad_rep7	3.5e-08
Vps41	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	HP_ad_rep7	4.8e-12
Vps41	GOBP_Protein_Targeting_To_Vacuole	Mouse	Brain	HP_ad_rep7	2.5e-11
Vps41	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	HP_ad_rep7	1.4e-09
Vps41	GOBP_Response_To_Starvation	Mouse	Brain	HP_ad_rep7	4.4e-12
Vps41	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Vps41	GOBP_Vacuolar_Transport	Mouse	Brain	HP_ad_rep7	1.2e-09
Vps41	GOBP_Cellular_Response_To_External_Stimulus	Mouse	Brain	HP_polb_rep9	4.1e-14
Vps41	GOBP_Cellular_Response_To_Extracellular_Stimulus	Mouse	Brain	HP_polb_rep9	1.7e-11
Vps41	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Vps41	GOBP_Membrane_Fusion	Mouse	Brain	HP_polb_rep9	6.9e-14
Vps41	GOBP_Membrane_Organization	Mouse	Brain	HP_polb_rep9	1.4e-13
Vps41	GOBP_Organelle_Fusion	Mouse	Brain	HP_polb_rep9	1.4e-10
Vps41	GOBP_Organelle_Membrane_Fusion	Mouse	Brain	HP_polb_rep9	1.5e-11
Vps41	GOBP_Protein_Localization_To_Vacuole	Mouse	Brain	HP_polb_rep9	1.3e-10
Vps41	GOBP_Protein_Targeting	Mouse	Brain	HP_polb_rep9	1.8e-11
Vps41	GOBP_Vesicle_Organization	Mouse	Brain	HP_polb_rep9	4.1e-14

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Vps41 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Vps41 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Vps41 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Vps41

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Vps41

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source