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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

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Cell cell interactions using single cell data

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Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Pou6f2 (spascer ID:218030)

Gene summary for Pou6f2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Pou6f2

Gene ID

218030

Gene namePOU domain, class 6, transcription factor 2
SynonymsD130006K24Rik|RPF-1
Cytomap13|13 A2
Type of geneprotein-coding
DescriptionPOU domain, class 6, transcription factor 2retina-derived POU-domain factor-1
Modification date20220424
UniProtAcc

Q8BJI4


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Pou6f2

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
Pou6f2

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Pou6f2

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process

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Spatial pattern events for Pou6f2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Pou6f2MouseEmbryorep_2 331887761.37e-14
Pou6f2MouseEmbryorep_5 331887761.33e-13

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map


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Spatial pattern pathway has Pou6f2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Pou6f2GOBP_Cell_Fate_DeterminationMouseSpinal cordL7bCN02_E1 7.6e-06
Pou6f2GOBP_Nervous_System_ProcessMouseSpinal cordL7bCN02_E1 2.5e-06
Pou6f2GOBP_Cell_Fate_CommitmentMouseSpinal cordL7CN45_C1 5.2e-07
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseSpinal cordL7CN45_C1 5.5e-10
Pou6f2GOBP_Sensory_PerceptionMouseSpinal cordL7CN45_C1 5.0e-07
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseSpinal cordL7CN45_C1 2.3e-08
Pou6f2GOBP_Cell_Fate_DeterminationMouseBrainrep_37 3.8e-06
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseBrainrep_71 5.8e-05
Pou6f2GOBP_Cell_Fate_DeterminationMouseBrainrep_1 2.0e-64
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseBrainrep_1 8.6e-30
Pou6f2GOBP_Nervous_System_ProcessMouseBrainrep_1 1.6e-36
Pou6f2GOBP_Cell_Fate_CommitmentMouseBrainrep_38.8e-182
Pou6f2GOBP_Sensory_PerceptionMouseBrainrep_3 2.9e-57
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseBrainrep_3 1.1e-51
Pou6f2GOBP_Cell_Fate_DeterminationMouseEmbryorep_14 2.5e-30
Pou6f2GOBP_Sensory_PerceptionMouseEmbryorep_14 5.0e-07
Pou6f2GOBP_Cell_Fate_CommitmentMouseEmbryorep_1 6.8e-22
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseEmbryorep_13.0e-261
Pou6f2GOBP_Nervous_System_ProcessMouseEmbryorep_1 1.4e-08
Pou6f2GOBP_Sensory_PerceptionMouseEmbryorep_3 0.0e+00
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseKidneyNep 4.2e-26
Pou6f2GOBP_Cell_Fate_CommitmentMouseKidneyrep_2 1.1e-65
Pou6f2GOBP_Cell_Fate_DeterminationMouseKidneyrep_2 1.2e-09
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseKidneyrep_2 1.3e-23
Pou6f2GOBP_Nervous_System_ProcessMouseKidneyrep_2 1.9e-90
Pou6f2GOBP_Sensory_PerceptionMouseKidneyrep_2 1.4e-94
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseKidneyrep_21.2e-132
Pou6f2GOBP_Nervous_System_ProcessMouseLiverCN73-C1 1.7e-08
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseLiverrep_16 8.2e-15
Pou6f2GOBP_Cell_Fate_CommitmentMouseLymphMS-1 2.1e-11
Pou6f2GOBP_Cell_Fate_DeterminationMouseLymphMS-1 4.2e-15
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseLymphMS-1 3.8e-07
Pou6f2GOBP_Nervous_System_ProcessMouseLymphMS-1 1.4e-08
Pou6f2GOBP_Sensory_PerceptionMouseLymphMS-1 5.2e-11
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseLymphMS-1 3.2e-08
Pou6f2GOBP_Cell_Fate_DeterminationMouseBrainHP_ad_rep2 8.6e-09
Pou6f2GOBP_Cell_Fate_CommitmentMouseBrainHP_ad_rep7 1.5e-09
Pou6f2GOBP_Central_Nervous_System_DevelopmentMouseBrainHP_ad_rep7 2.3e-07
Pou6f2GOBP_Nervous_System_ProcessMouseBrainHP_ad_rep7 7.0e-10
Pou6f2GOBP_Sensory_PerceptionMouseBrainHP_polb_rep9 1.2e-09
Pou6f2GOBP_Sensory_Perception_Of_Light_StimulusMouseBrainHP_polb_rep9 5.5e-10

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Pou6f2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Pou6f2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Pou6f2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Pou6f2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Pou6f2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Pou6f2C0004352Autistic Disorder1CTD_human
Pou6f2C1832099Wilms tumor and radial bilateral aplasia1CTD_human;UNIPROT