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Spatial pattern gene: Tbrg1 (spascer ID:21376) |
Gene summary for Tbrg1 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Tbrg1 | Gene ID | 21376 |
| Gene name | transforming growth factor beta regulated gene 1 |
| Synonyms | AA408552|AA409675|Niam|Tb-5|mFLJ00213 |
| Cytomap | 9|9 A4 |
| Type of gene | protein-coding |
| Description | transforming growth factor beta regulator 1nuclear interactor of ARF and Mdm2 |
| Modification date | 20220424 |
| UniProtAcc | Q3UB74 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Tbrg1 | GO:0005634 | nucleus | 21873635 | Component |
| Tbrg1 | GO:0051726 | regulation of cell cycle | 21873635 | Process |
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Spatial pattern events for Tbrg1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Tbrg1 | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Tbrg1 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Tbrg1 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Tbrg1 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Tbrg1 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Tbrg1 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Tbrg1 | Mouse | Brain | rep_1 | 35141374 | 1.42e-06 |
| Tbrg1 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Tbrg1 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Tbrg1 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Tbrg1 | Mouse | Brain | rep_5 | 35141374 | 1.40e-07 |
| Tbrg1 | Mouse | Brain | rep_6 | 35141374 | 7.95e-07 |
| Tbrg1 | Mouse | Embryo | rep_3 | 33188776 | 2.04e-13 |
| Tbrg1 | Mouse | Embryo | rep_5 | 33188776 | 2.18e-06 |
| Tbrg1 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Tbrg1 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Tbrg1 | Mouse | Kidney | Sham | 34003797 | 7.83e-15 |
| Tbrg1 | Mouse | Kidney | rep_1 | 34853151 | 7.83e-15 |
| Tbrg1 | Mouse | Kidney | rep_2 | 34853151 | 1.70e-08 |
| Tbrg1 | Mouse | Kidney | rep_3 | 34853151 | 8.84e-09 |
| Tbrg1 | Mouse | Kidney | rep_4 | 34853151 | 1.30e-09 |
| Tbrg1 | Mouse | Brain | rep_1 | 33469025 | 4.39e-14 |
| Tbrg1 | Mouse | Brain | rep_1 | 35027729 | 2.85e-08 |
| Tbrg1 | Mouse | Brain | rep_2 | 35027729 | 4.54e-10 |
| Tbrg1 | Mouse | Brain | rep_3 | 35027729 | 2.38e-15 |
| Tbrg1 | Mouse | Brain | rep_4 | 35027729 | 8.13e-12 |
| Tbrg1 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Tbrg1 | Mouse | Intestine | rep_2 | 35149721 | 7.47e-07 |
| Tbrg1 | Mouse | Intestine | rep_4 | 35149721 | 3.90e-15 |
| Tbrg1 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Tbrg1 | Mouse | Lymph | B1 | 0 | 3.55e-11 |
| Tbrg1 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Tbrg1 | Mouse | Lung | rep_2 | 35290801 | 1.85e-09 |
| Tbrg1 | Mouse | Lung | rep_3 | 35290801 | 8.40e-15 |
| Tbrg1 | Mouse | Lung | rep_4 | 35290801 | 3.04e-15 |
| Tbrg1 | Mouse | Brain | rep_1 | 35210624 | 5.49e-06 |
| Tbrg1 | Mouse | Brain | rep_2 | 35210624 | 1.91e-06 |
| Tbrg1 | Mouse | Brain | rep_3 | 35210624 | 1.89e-10 |
| Tbrg1 | Mouse | Brain | rep_5 | 35210624 | 7.03e-13 |
| Tbrg1 | Mouse | Brain | rep_7 | 35210624 | 1.92e-06 |
| Tbrg1 | Mouse | Brain | OFB_polb_rep5 | 33083725 | 1.63e-03 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_2_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
Brain_OFB_polb_rep5_H&E  |
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Spatial pattern pathway has Tbrg1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 1.1e-06 |
| Tbrg1 | GOBP_Cell_Cycle_Process | Mouse | Spinal cord | CN94_E1 | 3.8e-06 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 3.2e-06 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleus | Mouse | Spinal cord | CN94_E1 | 2.3e-06 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Spinal cord | CN94_E1 | 9.3e-07 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Spinal cord | L7CN45_C1 | 4.2e-07 |
| Tbrg1 | GOBP_Dna_Replication | Mouse | Spinal cord | L7CN45_C1 | 2.8e-07 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Mouse | Spinal cord | L7CN45_C1 | 1.3e-08 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Spinal cord | L7CN45_C1 | 1.2e-07 |
| Tbrg1 | GOBP_Protein_Localization_To_Organelle | Mouse | Spinal cord | L7CN45_C1 | 3.6e-07 |
| Tbrg1 | GOBP_Protein_Stabilization | Mouse | Spinal cord | L7CN45_C1 | 1.7e-07 |
| Tbrg1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Spinal cord | L7CN45_C1 | 3.0e-07 |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Brain | rep_27 | 8.4e-07 |
| Tbrg1 | GOBP_Dna_Replication | Mouse | Brain | rep_27 | 6.4e-06 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_27 | 1.7e-08 |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Brain | rep_1 | 7.0e-10 |
| Tbrg1 | GOBP_Cell_Cycle_Process | Mouse | Brain | rep_1 | 6.7e-14 |
| Tbrg1 | GOBP_Dna_Replication | Mouse | Brain | rep_1 | 4.3e-10 |
| Tbrg1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_1 | 3.9e-14 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Brain | rep_3 | 1.6e-125 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_3 | 1.9e-186 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Mouse | Brain | rep_3 | 1.6e-104 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Brain | rep_3 | 4.3e-182 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleus | Mouse | Brain | rep_3 | 1.1e-167 |
| Tbrg1 | GOBP_Protein_Localization_To_Organelle | Mouse | Brain | rep_3 | 6.3e-172 |
| Tbrg1 | GOBP_Protein_Stabilization | Mouse | Brain | rep_3 | 1.9e-142 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Brain | rep_3 | 3.1e-136 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Embryo | rep_14 | 6.4e-79 |
| Tbrg1 | GOBP_Protein_Stabilization | Mouse | Embryo | rep_14 | 3.2e-21 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Embryo | rep_14 | 4.3e-14 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Mouse | Embryo | rep_1 | 3.5e-170 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Embryo | rep_2 | 5.5e-15 |
| Tbrg1 | GOBP_Protein_Stabilization | Mouse | Embryo | rep_5 | 1.1e-25 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Embryo | rep_5 | 6.2e-09 |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Kidney | rep_2 | 1.0e-24 |
| Tbrg1 | GOBP_Cell_Cycle_Process | Mouse | Kidney | rep_2 | 3.0e-21 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Kidney | rep_2 | 3.5e-61 |
| Tbrg1 | GOBP_Dna_Replication | Mouse | Kidney | rep_2 | 5.9e-43 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Kidney | rep_2 | 2.8e-71 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Kidney | rep_2 | 1.4e-57 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleus | Mouse | Kidney | rep_2 | 1.4e-52 |
| Tbrg1 | GOBP_Protein_Localization_To_Organelle | Mouse | Kidney | rep_2 | 3.4e-44 |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Lymph | MS-1 | 1.3e-07 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Lymph | MS-1 | 1.1e-11 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Lymph | MS-1 | 9.2e-07 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Mouse | Lymph | MS-1 | 5.6e-14 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Lymph | MS-1 | 4.5e-13 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleus | Mouse | Lymph | MS-1 | 3.2e-15 |
| Tbrg1 | GOBP_Protein_Localization_To_Organelle | Mouse | Lymph | MS-1 | 1.4e-09 |
| Tbrg1 | GOBP_Protein_Stabilization | Mouse | Lymph | MS-1 | 5.9e-10 |
| Tbrg1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Lymph | MS-1 | 6.4e-09 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Lymph | MS-1 | 1.0e-14 |
| Tbrg1 | GOBP_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 6.6e-08 |
| Tbrg1 | GOBP_Cell_Cycle_Process | Mouse | Brain | HP_ad_rep7 | 1.7e-09 |
| Tbrg1 | GOBP_Cellular_Macromolecule_Localization | Mouse | Brain | HP_ad_rep7 | 6.6e-10 |
| Tbrg1 | GOBP_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 1.1e-10 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 9.2e-08 |
| Tbrg1 | GOBP_Protein_Localization_To_Organelle | Mouse | Brain | HP_ad_rep7 | 4.8e-12 |
| Tbrg1 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleoplasm | Mouse | Brain | HP_adpolb_rep1 | 3.7e-11 |
| Tbrg1 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Mouse | Brain | HP_polb_rep9 | 2.8e-10 |
| Tbrg1 | GOBP_Protein_Localization_To_Nucleus | Mouse | Brain | HP_polb_rep9 | 2.3e-09 |
| Tbrg1 | GOBP_Regulation_Of_Protein_Stability | Mouse | Brain | HP_polb_rep9 | 8.6e-09 |
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Tbrg1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Tbrg1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Tbrg1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Tbrg1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Tbrg1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
