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Spatial pattern gene: Tagln2 (spascer ID:21346) |
Gene summary for Tagln2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Tagln2 | Gene ID | 21346 |
| Gene name | transgelin 2 |
| Synonyms | 2700094C18Rik|SM22beta|Sm22B|Sm22a |
| Cytomap | 1 H3|1 79.89 cM |
| Type of gene | protein-coding |
| Description | transgelin-2SM22-beta |
| Modification date | 20220424 |
| UniProtAcc | Q9WVA4 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Tagln2 | GO:0005856 | cytoskeleton | 21873635 | Component |
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Spatial pattern events for Tagln2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Tagln2 | Mouse | Brain | S1 | 34413515 | 4.15e-11 |
| Tagln2 | Mouse | Brain | S2 | 34413515 | 2.85e-15 |
| Tagln2 | Mouse | Brain | S3 | 34413515 | 2.96e-15 |
| Tagln2 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Tagln2 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Tagln2 | Mouse | Brain | S7 | 34413515 | 7.67e-14 |
| Tagln2 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Tagln2 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Tagln2 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Tagln2 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Tagln2 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Tagln2 | Mouse | Embryo | 4E | 34210887 | 7.64e-11 |
| Tagln2 | Mouse | Embryo | rep_2 | 33188776 | 2.32e-07 |
| Tagln2 | Mouse | Embryo | rep_3 | 33188776 | 3.28e-14 |
| Tagln2 | Mouse | Embryo | rep_5 | 33188776 | 2.54e-11 |
| Tagln2 | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Tagln2 | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Tagln2 | Mouse | Embryo | rep_15 | 33188776 | 5.97e-15 |
| Tagln2 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Tagln2 | Mouse | Kidney | Sham | 34003797 | 7.83e-15 |
| Tagln2 | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Tagln2 | Mouse | Kidney | rep_2 | 34853151 | 3.38e-15 |
| Tagln2 | Mouse | Kidney | rep_3 | 34853151 | 4.93e-15 |
| Tagln2 | Mouse | Kidney | rep_4 | 34853151 | 6.52e-07 |
| Tagln2 | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Tagln2 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Tagln2 | Mouse | Liver | rep_20 | 35021063 | 9.91e-15 |
| Tagln2 | Mouse | Liver | rep_21 | 35021063 | 8.03e-15 |
| Tagln2 | Mouse | Liver | rep_22 | 35021063 | 1.07e-14 |
| Tagln2 | Mouse | Brain | rep_1 | 35027729 | 4.47e-06 |
| Tagln2 | Mouse | Brain | rep_2 | 35027729 | 1.94e-11 |
| Tagln2 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Tagln2 | Mouse | Brain | rep_5 | 35027729 | 2.62e-15 |
| Tagln2 | Mouse | Intestine | rep_1 | 35149721 | 3.84e-06 |
| Tagln2 | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Tagln2 | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Tagln2 | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Tagln2 | Mouse | Lymph | MS-2 | 0 | 3.70e-08 |
| Tagln2 | Mouse | Lymph | PBS | 0 | 1.47e-13 |
| Tagln2 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Tagln2 | Mouse | Lymph | B1 | 0 | 4.31e-14 |
| Tagln2 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Tagln2 | Mouse | Lung | rep_2 | 35290801 | 8.75e-15 |
| Tagln2 | Mouse | Lung | rep_3 | 35290801 | 5.26e-15 |
| Tagln2 | Mouse | Lung | rep_4 | 35290801 | 3.04e-15 |
| Tagln2 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Tagln2 | Mouse | Brain | rep_2 | 35210624 | 6.34e-10 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_2_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Liver_rep_20_H&E  | |
Liver_rep_21_H&E  | |
Liver_rep_22_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
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Spatial pattern pathway has Tagln2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Spinal cord | CN93_D2 | 4.3e-07 |
| Tagln2 | GOBP_Epithelial_Cell_Differentiation | Mouse | Spinal cord | CN94_E1 | 2.3e-07 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Spinal cord | L7CN45_C1 | 4.2e-06 |
| Tagln2 | GOBP_Secretion | Mouse | Spinal cord | L7CN45_C1 | 8.1e-09 |
| Tagln2 | GOBP_Exocytosis | Mouse | Spinal cord | L7CN47_C1 | 7.4e-07 |
| Tagln2 | GOBP_Secretion | Mouse | Brain | rep_27 | 8.9e-05 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Brain | rep_37 | 7.2e-06 |
| Tagln2 | GOBP_Exocytosis | Mouse | Brain | rep_1 | 3.4e-73 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Brain | rep_1 | 1.3e-96 |
| Tagln2 | GOBP_Secretion | Mouse | Brain | rep_1 | 4.1e-45 |
| Tagln2 | GOBP_Epithelial_Cell_Differentiation | Mouse | Brain | rep_3 | 4.7e-108 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Brain | rep_3 | 8.3e-102 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Embryo | rep_14 | 1.1e-12 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Embryo | rep_1 | 1.7e-09 |
| Tagln2 | GOBP_Epithelial_Cell_Differentiation | Mouse | Kidney | rep_2 | 4.2e-114 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Kidney | rep_2 | 3.5e-92 |
| Tagln2 | GOBP_Exocytosis | Mouse | Kidney | rep_2 | 3.2e-107 |
| Tagln2 | GOBP_Secretion | Mouse | Kidney | rep_2 | 1.6e-23 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Liver | rep_14 | 3.1e-12 |
| Tagln2 | GOBP_Exocytosis | Mouse | Liver | rep_16 | 8.5e-07 |
| Tagln2 | GOBP_Epithelial_Cell_Differentiation | Mouse | Lymph | MS-1 | 1.2e-07 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Lymph | MS-1 | 8.5e-09 |
| Tagln2 | GOBP_Exocytosis | Mouse | Lymph | MS-1 | 1.4e-14 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Lymph | MS-1 | 8.6e-08 |
| Tagln2 | GOBP_Secretion | Mouse | Lymph | MS-1 | 2.3e-12 |
| Tagln2 | GOBP_Exocytosis | Mouse | Brain | rep_4 | 2.4e-43 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Brain | rep_4 | 2.8e-58 |
| Tagln2 | GOBP_Platelet_Degranulation | Mouse | Brain | HP_ad_rep3 | 5.8e-07 |
| Tagln2 | GOBP_Epithelial_Cell_Differentiation | Mouse | Brain | HP_ad_rep7 | 1.7e-13 |
| Tagln2 | GOBP_Epithelium_Development | Mouse | Brain | HP_ad_rep7 | 2.8e-08 |
| Tagln2 | GOBP_Secretion | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Tagln2 | GOBP_Exocytosis | Mouse | Brain | HP_polb_rep9 | 2.3e-13 |
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Tagln2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Tagln2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication | ||
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Transcription factor for Tagln2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Tagln2 | Liver | WD_36week | KC | Tppp3,Lgals1,Plec, etc. | 0.264 |
| Tagln2 | Liver | WD_36week | Unclear | Tppp3,Lgals1,Plec, etc. | 0.258 |
| Tagln2 | Liver | WD_36week | Monocyte | Tppp3,Lgals1,Plec, etc. | 0.473 |
| Tagln2 | Liver | WD_36week | cDC1 | Tppp3,Lgals1,Plec, etc. | 0.253 |
| Tagln2 | Liver | WD_36week | T cells | Tppp3,Lgals1,Plec, etc. | 0.273 |
| Tagln2 | Liver | WD_36week | cDC2 | Tppp3,Lgals1,Plec, etc. | 0.256 |
| TAGLN2 | Uterus | mid | Glandular_secretory | AGPAT2,CRIP1,ACTG1, etc. | 0.717 |
| TAGLN2 | Uterus | mid | Glandular | AGPAT2,CRIP1,ACTG1, etc. | 0.285 |
| Tagln2 | Kidney | IRI | PT_S1 | Actg1,Capns1,Cd151, etc. | 0.305 |
| Tagln2 | Kidney | IRI | CNT | Actg1,Capns1,Cd151, etc. | 0.256 |
| Tagln2 | Kidney | IRI | PT_S3_C | Actg1,Capns1,Cd151, etc. | 0.285 |
| Tagln2 | Kidney | IRI | PT_Fibrinogen | Actg1,Capns1,Cd151, etc. | 0.262 |
| Tagln2 | Kidney | IRI | CD_IC | Actg1,Capns1,Cd151, etc. | 0.267 |
| Tagln2 | Kidney | IRI | TAL | Actg1,Capns1,Cd151, etc. | 0.288 |
| Tagln2 | Kidney | IRI | CD_PC | Actg1,Capns1,Cd151, etc. | 0.271 |
| Tagln2 | Lymph | disease | CD8 T | Actg1,Lsp1,Tmbim6, etc. | 0.265 |
| Tagln2 | Lymph | disease | Ifit3 high B | Actg1,Lsp1,Tmbim6, etc. | 0.296 |
| Tagln2 | Lymph | disease | CD4 T | Actg1,Lsp1,Tmbim6, etc. | 0.257 |
| Tagln2 | Lymph | disease | Ifit3 high CD8 T | Actg1,Lsp1,Tmbim6, etc. | 0.251 |
| Tagln2 | Lymph | disease | Mature B | Actg1,Lsp1,Tmbim6, etc. | 0.332 |
| TAGLN2 | Uterus | proliferative | SOX9 | CALM2,TUBB4B,ANXA11, etc. | 0.495 |
| TAGLN2 | Uterus | proliferative | Ciliated | CALM2,TUBB4B,ANXA11, etc. | 0.295 |
| TAGLN2 | Uterus | proliferative | SOX9_LGR5 | CALM2,TUBB4B,ANXA11, etc. | 0.341 |
| TAGLN2 | Uterus | proliferative | SOX9_prolif | CALM2,TUBB4B,ANXA11, etc. | 0.346 |
| Tagln2 | Liver | SD_12week | Monocyte | Tppp3,Lgals1,Capg, etc. | 0.423 |
| Tagln2 | Liver | SD_12week | pDCs | Tppp3,Lgals1,Capg, etc. | 0.31 |
| Tagln2 | Liver | SD_12week | cDC1 | Tppp3,Lgals1,Capg, etc. | 0.278 |
| Tagln2 | Liver | SD_12week | cDC2 | Tppp3,Lgals1,Capg, etc. | 0.298 |
| Tagln2 | Liver | SD_12week | KC | Tppp3,Lgals1,Capg, etc. | 0.285 |
| Tagln2 | Kidney | Sham | CNT | Sparc,Sulf2,Cmtm7, etc. | 0.263 |
| Tagln2 | Kidney | Sham | PT_S3_C | Sparc,Sulf2,Cmtm7, etc. | 0.349 |
| Tagln2 | Kidney | Sham | VSM | Sparc,Sulf2,Cmtm7, etc. | 0.274 |
| Tagln2 | Kidney | Sham | PT_S1 | Sparc,Sulf2,Cmtm7, etc. | 0.271 |
| Tagln2 | Kidney | Sham | TAL | Sparc,Sulf2,Cmtm7, etc. | 0.315 |
| Tagln2 | Kidney | Sham | DCT | Sparc,Sulf2,Cmtm7, etc. | 0.253 |
| Tagln2 | Kidney | Sham | PT_S2 | Sparc,Sulf2,Cmtm7, etc. | 0.251 |
| Motif information. |
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Related Drugs for Tagln2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Tagln2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
