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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Dse (spascer ID:212898)

Gene summary for Dse

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Dse
	Gene ID	212898
	Gene name	dermatan sulfate epimerase
	Synonyms	6030499O08\|AI480506\|B130024B19Rik\|DS-epi1\|Sart2
	Cytomap	10\|10 B1
	Type of gene	protein-coding
	Description	dermatan-sulfate epimeraseDS epimerasechondroitin-glucuronate 5-epimerasesquamous cell carcinoma antigen recognized by T cells 2
	Modification date	20220424
	UniProtAcc	Q8BLI4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Dse	GO:0030204	chondroitin sulfate metabolic process	21873635	Process
Dse	GO:0030205	dermatan sulfate metabolic process	21873635	Process
Dse	GO:0047757	chondroitin-glucuronate 5-epimerase activity	21873635	Function

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Spatial pattern events for Dse

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Dse	Mouse	Embryo	rep_3	33188776	1.06e-07
Dse	Mouse	Embryo	rep_5	33188776	4.74e-07
Dse	Mouse	Kidney	rep_5	34853151	1.48e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E

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Spatial pattern pathway has Dse envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-06
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	CN95_C1	3.1e-06
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Spinal cord	L7bCN01_D2	9.0e-06
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7bCN02_E1	1.8e-07
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.3e-06
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.1e-06
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.4e-07
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_C1	1.3e-06
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN47_D1	4.0e-07
Dse	GOBP_Mucopolysaccharide_Metabolic_Process	Mouse	Spinal cord	L7CN47_D1	1.8e-08
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Brain	rep_7	1.2e-05
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_19	7.6e-05
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_23	2.6e-05
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_27	4.3e-05
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_71	9.4e-05
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_74	5.3e-05
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_74	9.0e-05
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_75	2.9e-05
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_1	2.1e-28
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_1	4.4e-35
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_1	7.2e-44
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Brain	rep_1	8.2e-08
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Brain	rep_3	3.9e-113
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	rep_3	2.7e-27
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Brain	rep_3	2.2e-102
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_3	2.6e-107
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Brain	rep_3	1.7e-62
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	6.4e-155
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	rep_3	1.9e-173
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_3	1.6e-113
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_3	2.2e-99
Dse	GOBP_Mucopolysaccharide_Metabolic_Process	Mouse	Brain	rep_3	1.4e-123
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_3	3.5e-98
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_3	4.8e-70
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	rep_3	1.4e-160
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-44
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Embryo	rep_14	8.7e-35
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Embryo	rep_14	4.5e-09
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Embryo	rep_14	1.8e-47
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	1.2e-52
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-37
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-22
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-40
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	3.8e-33
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-45
Dse	GOBP_Mucopolysaccharide_Metabolic_Process	Mouse	Embryo	rep_14	5.1e-28
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	8.9e-07
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-20
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	3.3e-48
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Embryo	rep_14	5.8e-13
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Kidney	rep_2	1.3e-08
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Kidney	rep_2	5.9e-30
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Kidney	rep_2	9.0e-111
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Kidney	rep_2	1.3e-19
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Kidney	rep_2	4.8e-14
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	2.5e-89
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-102
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Kidney	rep_2	4.1e-08
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-10
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Kidney	rep_2	1.1e-51
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-30
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Kidney	rep_2	8.6e-17
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Liver	CN16-D1	3.0e-07
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Liver	CN16-D2	7.9e-08
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Liver	CN73-C1	9.1e-08
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.2e-07
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Liver	CN73-C1	9.7e-08
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-07
Dse	GOBP_Mucopolysaccharide_Metabolic_Process	Mouse	Liver	CN73-C1	1.2e-07
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.0e-08
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Liver	rep_16	2.1e-07
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	rep_16	2.6e-08
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Liver	rep_23	8.4e-07
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Liver	rep_23	1.3e-07
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_1	2.8e-06
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Brain	rep_1	1.1e-09
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Intestine	rep_2	1.3e-108
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Intestine	rep_2	1.4e-120
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Intestine	rep_2	9.2e-102
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Intestine	rep_2	7.1e-07
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Intestine	rep_3	5.9e-15
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Intestine	rep_3	2.9e-47
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.1e-16
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-14
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Lymph	MS-1	9.2e-12
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	7.7e-09
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	1.2e-08
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-12
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	4.4e-07
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-07
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.1e-07
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	1.5e-11
Dse	GOBP_Mucopolysaccharide_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-14
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.6e-20
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	7.9e-14
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	4.5e-10
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Lymph	MS-1	7.8e-10
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Lung	rep_1	1.8e-12
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Lung	rep_1	5.5e-19
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lung	rep_1	1.7e-36
Dse	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lung	rep_1	2.2e-08
Dse	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Lung	rep_1	5.9e-09
Dse	GOBP_Proteoglycan_Metabolic_Process	Mouse	Lung	rep_1	1.1e-19
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_4	1.4e-08
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_4	1.8e-21
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_4	5.3e-32
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Brain	rep_4	1.8e-15
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Brain	rep_7	1.7e-72
Dse	GOBP_Dermatan_Sulfate_Metabolic_Process	Mouse	Brain	HP_ad_rep3	7.8e-09
Dse	GOBP_Dermatan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	HP_ad_rep3	8.8e-09
Dse	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.9e-08
Dse	GOBP_Aminoglycan_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.6e-11
Dse	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	9.8e-07
Dse	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Dse	GOBP_Chondroitin_Sulfate_Biosynthetic_Process	Mouse	Brain	HP_ad_rep8	3.3e-10
Dse	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	2.0e-07
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	HP_adpolb_rep5	2.2e-07
Dse	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Dse	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.4e-10
Dse	GOBP_Sulfur_Compound_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.2e-10
Dse	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-08
Dse	GOBP_Chondroitin_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	HP_polb_rep7	2.0e-04

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Dse function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Dse function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Dse envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Dse

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Dse

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Dse	C3809845	EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE, 2	2	CTD_human;GENOMICS_ENGLAND;UNIPROT
Dse	C1866294	EHLERS-DANLOS SYNDROME, MUSCULOCONTRACTURAL TYPE 1	1	ORPHANET