Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tifa (spascer ID:211550)

Gene summary for Tifa

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tifa
	Gene ID	211550
	Gene name	TRAF-interacting protein with forkhead-associated domain
	Synonyms	T2bp
	Cytomap	3\|3 G2
	Type of gene	protein-coding
	Description	TRAF-interacting protein with FHA domain-containing protein ATraf2 binding protein
	Modification date	20220424
	UniProtAcc	Q793I8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tifa	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	21873635	Process
Tifa	GO:0005737	cytoplasm	21873635	Component
Tifa	GO:0007249	I-kappaB kinase/NF-kappaB signaling	21873635	Process
Tifa	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	21873635	Process
Tifa	GO:0045087	innate immune response	21873635	Process

Top

Spatial pattern events for Tifa

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tifa	Mouse	Brain	S1	34413515	3.47e-13
Tifa	Mouse	Brain	S2	34413515	1.56e-15
Tifa	Mouse	Brain	S4	34413515	1.55e-11
Tifa	Mouse	Brain	S6	34413515	1.46e-15
Tifa	Mouse	Brain	S7	34413515	1.55e-15
Tifa	Mouse	Brain	rep_4	35141374	1.57e-15
Tifa	Mouse	Brain	rep_5	35141374	1.73e-10
Tifa	Mouse	Kidney	CLP	34003797	4.72e-14
Tifa	Mouse	Intestine	rep_3	35149721	3.25e-15
Tifa	Mouse	Intestine	rep_4	35149721	2.30e-15
Tifa	Mouse	Lung	rep_4	35290801	6.00e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Lung_rep_4_H&E

Top

Spatial pattern pathway has Tifa envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tifa	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	1.1e-06
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Spinal cord	L7bCN02_E1	6.8e-06
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Spinal cord	L7CN45_C1	9.1e-07
Tifa	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Tifa	GOBP_Protein_Homooligomerization	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN47_C1	3.1e-07
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Spinal cord	L7CN97_E2	7.9e-07
Tifa	GOBP_Innate_Immune_Response	Mouse	Spinal cord	L7CN97_E2	2.7e-06
Tifa	GOBP_Defense_Response	Mouse	Spinal cord	L8CN11_C1	3.3e-17
Tifa	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	7.6e-06
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	rep_1	1.3e-08
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	6.5e-10
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	2.7e-08
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Brain	rep_1	3.1e-07
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Brain	rep_1	8.5e-20
Tifa	GOBP_Protein_Homooligomerization	Mouse	Brain	rep_1	1.2e-17
Tifa	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	3.8e-128
Tifa	GOBP_Defense_Response	Mouse	Brain	rep_3	8.7e-77
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	rep_3	6.0e-105
Tifa	GOBP_Innate_Immune_Response	Mouse	Brain	rep_3	7.5e-97
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	rep_3	9.2e-94
Tifa	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	3.3e-214
Tifa	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Tifa	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	8.6e-45
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Embryo	rep_14	6.2e-28
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	5.2e-24
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Embryo	rep_14	1.9e-23
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Embryo	rep_14	9.3e-21
Tifa	GOBP_Protein_Homooligomerization	Mouse	Embryo	rep_14	4.9e-14
Tifa	GOBP_Defense_Response	Mouse	Embryo	rep_1	5.2e-63
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Embryo	rep_1	5.7e-69
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Embryo	rep_2	1.4e-07
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Embryo	rep_3	2.6e-164
Tifa	GOBP_Innate_Immune_Response	Mouse	Embryo	rep_3	2.0e-259
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Embryo	rep_3	1.5e-141
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	1.9e-15
Tifa	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	Nep	5.3e-07
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Kidney	Nep	1.1e-39
Tifa	GOBP_Defense_Response	Mouse	Kidney	rep_2	6.8e-127
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Kidney	rep_2	2.3e-129
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Kidney	rep_2	1.5e-43
Tifa	GOBP_Innate_Immune_Response	Mouse	Kidney	rep_2	3.1e-117
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Kidney	rep_2	2.0e-70
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Kidney	rep_2	3.4e-17
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Kidney	rep_2	2.8e-82
Tifa	GOBP_Protein_Homooligomerization	Mouse	Kidney	rep_2	3.3e-85
Tifa	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Tifa	GOBP_Defense_Response	Mouse	Liver	rep_16	8.0e-16
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Liver	rep_16	1.8e-13
Tifa	GOBP_Innate_Immune_Response	Mouse	Liver	rep_16	5.5e-09
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.6e-08
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.7e-07
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Liver	rep_16	5.4e-07
Tifa	GOBP_Defense_Response	Mouse	Lymph	MS-1	8.6e-18
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Lymph	MS-1	6.7e-20
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Lymph	MS-1	2.7e-15
Tifa	GOBP_Innate_Immune_Response	Mouse	Lymph	MS-1	6.7e-20
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.7e-11
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.1e-09
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Lymph	MS-1	3.7e-16
Tifa	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	2.3e-12
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Lymph	MS-1	2.3e-12
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Lymph	MS-1	2.9e-20
Tifa	GOBP_Protein_Homooligomerization	Mouse	Lymph	MS-1	1.2e-10
Tifa	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Tifa	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Lymph	PBS	4.8e-07
Tifa	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep3	2.6e-16
Tifa	GOBP_Defense_Response	Mouse	Brain	HP_ad_rep7	5.6e-10
Tifa	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.5e-10
Tifa	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.1e-10
Tifa	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	HP_ad_rep7	1.9e-07
Tifa	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	HP_polb_rep9	2.1e-11
Tifa	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	HP_polb_rep9	1.8e-10
Tifa	GOBP_Innate_Immune_Response	Mouse	Brain	HP_polb_rep9	3.9e-11
Tifa	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	1.7e-14
Tifa	GOBP_Positive_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.3e-14
Tifa	GOBP_Protein_Complex_Oligomerization	Mouse	Brain	HP_polb_rep9	2.7e-11
Tifa	GOBP_Protein_Homooligomerization	Mouse	Brain	HP_polb_rep9	1.8e-12
Tifa	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11

Top

Tifa function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Tifa function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Tifa envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Tifa

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Tifa

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source