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Spatial pattern gene: Lpp (spascer ID:210126) |
Gene summary for Lpp |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Lpp | Gene ID | 210126 |
| Gene name | LIM domain containing preferred translocation partner in lipoma |
| Synonyms | 9430020K16Rik|AA959454|AU024130|B130055L10Rik|C79715|D630048H16 |
| Cytomap | 16|16 B1 |
| Type of gene | protein-coding |
| Description | lipoma-preferred partner homologlipoma preferred partner |
| Modification date | 20220424 |
| UniProtAcc | Q8BFW7 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Lpp | GO:0001725 | stress fiber | 21873635 | Component |
| Lpp | GO:0005925 | focal adhesion | 21873635 | Component |
| Lpp | GO:0098609 | cell-cell adhesion | 21873635 | Process |
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Spatial pattern events for Lpp |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Lpp | Mouse | Embryo | 1D | 34210887 | 7.59e-12 |
| Lpp | Mouse | Embryo | 1E | 34210887 | 7.50e-15 |
| Lpp | Mouse | Embryo | 1F | 34210887 | 7.91e-15 |
| Lpp | Mouse | Embryo | 1G | 34210887 | 5.28e-14 |
| Lpp | Mouse | Embryo | 2G | 34210887 | 1.06e-14 |
| Lpp | Mouse | Embryo | 2H | 34210887 | 5.31e-15 |
| Lpp | Mouse | Embryo | 3D | 34210887 | 1.03e-10 |
| Lpp | Mouse | Embryo | 3F | 34210887 | 1.83e-11 |
| Lpp | Mouse | Embryo | 3G | 34210887 | 2.60e-10 |
| Lpp | Mouse | Embryo | 4C | 34210887 | 2.25e-07 |
| Lpp | Mouse | Embryo | 4D | 34210887 | 2.00e-11 |
| Lpp | Mouse | Embryo | 4E | 34210887 | 4.53e-15 |
| Lpp | Mouse | Embryo | rep_1 | 33188776 | 4.74e-08 |
| Lpp | Mouse | Embryo | rep_2 | 33188776 | 1.37e-14 |
| Lpp | Mouse | Embryo | rep_3 | 33188776 | 1.13e-14 |
| Lpp | Mouse | Embryo | rep_4 | 33188776 | 8.29e-15 |
| Lpp | Mouse | Embryo | rep_5 | 33188776 | 1.40e-14 |
| Lpp | Mouse | Embryo | rep_7 | 33188776 | 6.94e-15 |
| Lpp | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Lpp | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Lpp | Mouse | Kidney | IRI | 34003797 | 7.37e-15 |
| Lpp | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Lpp | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Lpp | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Lpp | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Lpp | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Lpp | Mouse | Intestine | rep_1 | 35149721 | 1.81e-14 |
| Lpp | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Lpp | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Lpp | Mouse | Intestine | rep_4 | 35149721 | 3.90e-15 |
| Lpp | Mouse | Lung | rep_1 | 35290801 | 1.25e-10 |
| Lpp | Mouse | Lung | rep_2 | 35290801 | 5.15e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_IRI_H&E  |  |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
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Spatial pattern pathway has Lpp envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Lpp | GOBP_Biological_Adhesion | Mouse | Spinal cord | L7CN45_C1 | 2.4e-08 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Spinal cord | L7CN45_C1 | 6.8e-10 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Brain | rep_3 | 4.3e-106 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Brain | rep_3 | 5.2e-118 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Embryo | rep_1 | 2.2e-19 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Kidney | rep_2 | 1.3e-48 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Kidney | rep_2 | 1.1e-24 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Liver | rep_16 | 2.1e-07 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Liver | rep_16 | 1.4e-11 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Lymph | MS-1 | 8.0e-14 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Lymph | MS-1 | 1.9e-13 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Lung | rep_1 | 3.0e-22 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Lung | rep_1 | 2.9e-07 |
| Lpp | GOBP_Biological_Adhesion | Mouse | Brain | HP_polb_rep9 | 1.5e-07 |
| Lpp | GOBP_Cell_Cell_Adhesion | Mouse | Brain | HP_polb_rep9 | 3.6e-11 |
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Lpp function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Lpp function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Lpp envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Lpp |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Lpp |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Lpp | C0087031 | Juvenile-Onset Still Disease | 1 | CTD_human |
| Lpp | C3495559 | Juvenile arthritis | 1 | CTD_human |
| Lpp | C3714758 | Juvenile psoriatic arthritis | 1 | CTD_human |
| Lpp | C4552091 | Polyarthritis, Juvenile, Rheumatoid Factor Negative | 1 | CTD_human |
| Lpp | C4704862 | Polyarthritis, Juvenile, Rheumatoid Factor Positive | 1 | CTD_human |
