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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Surf4 (spascer ID:20932)

Gene summary for Surf4

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Surf4
	Gene ID	20932
	Gene name	surfeit gene 4
	Synonyms	AL033340\|AL033373\|Surf-4
	Cytomap	2 A3\|2 19.1 cM
	Type of gene	protein-coding
	Description	surfeit locus protein 4
	Modification date	20220424
	UniProtAcc	Q64310

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Surf4	GO:0005783	endoplasmic reticulum	21873635	Component
Surf4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	21873635	Component
Surf4	GO:0007030	Golgi organization	21873635	Process

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Spatial pattern events for Surf4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Surf4	Mouse	Brain	S4	34413515	1.37e-15
Surf4	Mouse	Brain	S6	34413515	1.46e-15
Surf4	Mouse	Brain	rep_1	35141374	2.42e-08
Surf4	Mouse	Brain	rep_5	35141374	1.47e-15
Surf4	Mouse	Brain	rep_6	35141374	1.73e-15
Surf4	Mouse	Embryo	2H	34210887	6.74e-06
Surf4	Mouse	Embryo	4E	34210887	1.51e-08
Surf4	Mouse	Kidney	rep_4	34853151	4.39e-06
Surf4	Mouse	Brain	rep_1	33469025	8.49e-06
Surf4	Mouse	Brain	rep_3	35027729	1.32e-15
Surf4	Mouse	Brain	rep_5	35027729	1.69e-08
Surf4	Mouse	Intestine	rep_3	35149721	9.60e-15
Surf4	Mouse	Intestine	rep_4	35149721	2.30e-15
Surf4	Mouse	Testicle	rep_1	34731600	1.08e-11
Surf4	Mouse	Lung	rep_1	35290801	4.21e-14
Surf4	Mouse	Lung	rep_2	35290801	3.88e-13
Surf4	Mouse	Lung	rep_4	35290801	3.04e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_4_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Surf4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Surf4	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Spinal cord	L7CN45_C1	9.9e-07
Surf4	GOBP_Endomembrane_System_Organization	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Surf4	GOBP_Golgi_Organization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Surf4	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	6.7e-06
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Spinal cord	L7CN45_C1	3.0e-06
Surf4	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Surf4	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Spinal cord	L7CN47_C1	5.1e-06
Surf4	GOBP_Golgi_Organization	Mouse	Brain	rep_27	5.4e-06
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Brain	rep_27	5.1e-06
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_27	3.0e-05
Surf4	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Surf4	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Surf4	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_1	2.6e-13
Surf4	GOBP_Endomembrane_System_Organization	Mouse	Brain	rep_1	7.8e-10
Surf4	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Surf4	GOBP_Golgi_Organization	Mouse	Brain	rep_1	5.5e-18
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Brain	rep_1	1.2e-15
Surf4	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_1	2.1e-07
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_1	1.3e-13
Surf4	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	2.2e-17
Surf4	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	7.9e-20
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Brain	rep_1	2.4e-31
Surf4	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	rep_3	7.0e-65
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.3e-32
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_6	1.4e-16
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Embryo	rep_14	5.7e-09
Surf4	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	3.8e-12
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Embryo	rep_14	2.9e-28
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	1.7e-32
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Embryo	rep_14	5.9e-39
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_2	3.4e-34
Surf4	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Embryo	rep_2	2.3e-14
Surf4	GOBP_Regulation_Of_Organelle_Organization	Mouse	Embryo	rep_3	1.3e-27
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	Nep	4.2e-26
Surf4	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Kidney	rep_2	4.3e-101
Surf4	GOBP_Endomembrane_System_Organization	Mouse	Kidney	rep_2	1.0e-161
Surf4	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Surf4	GOBP_Golgi_Organization	Mouse	Kidney	rep_2	3.2e-78
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Kidney	rep_2	6.5e-131
Surf4	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	2.7e-133
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Kidney	rep_2	2.2e-110
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	6.6e-105
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Kidney	rep_2	2.4e-38
Surf4	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	4.1e-12
Surf4	GOBP_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	6.7e-77
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Kidney	rep_2	3.5e-85
Surf4	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Liver	rep_15	2.4e-09
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Liver	rep_16	1.6e-18
Surf4	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Liver	rep_16	2.2e-20
Surf4	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Lymph	MS-1	9.7e-16
Surf4	GOBP_Endomembrane_System_Organization	Mouse	Lymph	MS-1	2.5e-09
Surf4	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Surf4	GOBP_Golgi_Organization	Mouse	Lymph	MS-1	9.6e-08
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Lymph	MS-1	5.2e-08
Surf4	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	5.6e-21
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Lymph	MS-1	1.0e-18
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	6.6e-07
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Lymph	MS-1	1.8e-09
Surf4	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	2.8e-08
Surf4	GOBP_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	1.4e-10
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Lymph	MS-1	4.2e-07
Surf4	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_4	2.9e-33
Surf4	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Surf4	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	6.4e-19
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_4	3.5e-20
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.7e-62
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Brain	rep_4	1.1e-19
Surf4	GOBP_Golgi_Organization	Mouse	Brain	HP_ad_rep7	2.6e-07
Surf4	GOBP_Golgi_Vesicle_Transport	Mouse	Brain	HP_ad_rep7	1.1e-09
Surf4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_ad_rep7	4.4e-14
Surf4	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	HP_ad_rep7	2.0e-07
Surf4	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	3.5e-08
Surf4	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	8.1e-07
Surf4	GOBP_Retrograde_Vesicle_Mediated_Transport_Golgi_To_Endoplasmic_Reticulum	Mouse	Brain	HP_ad_rep7	1.2e-09
Surf4	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Surf4	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Surf4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	HP_polb_rep9	8.8e-09
Surf4	GOBP_Endomembrane_System_Organization	Mouse	Brain	HP_polb_rep9	6.0e-11
Surf4	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Surf4	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Surf4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_polb_rep9	2.8e-07
Surf4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	HP_polb_rep9	2.6e-11

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Surf4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Surf4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Surf4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Surf4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Surf4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Surf4	C0033578	Prostatic Neoplasms	1	CTD_human
Surf4	C0376358	Malignant neoplasm of prostate	1	CTD_human