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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Eif1 (spascer ID:20918)

Gene summary for Eif1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Eif1
	Gene ID	20918
	Gene name	eukaryotic translation initiation factor 1
	Synonyms	Sui1-rs1
	Cytomap	11\|11 D
	Type of gene	protein-coding
	Description	eukaryotic translation initiation factor 1protein translation factor SUI1 homologsuppressor of initiator codon mutations, related sequence 1suppressor of initiator codon mutations-Yeast homolog related sequence 1
	Modification date	20220424
	UniProtAcc	P48024

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Eif1	GO:0003723	RNA binding	21873635	Function
Eif1	GO:0003743	translation initiation factor activity	21873635	Function
Eif1	GO:0016282	eukaryotic 43S preinitiation complex	21873635	Component
Eif1	GO:0043024	ribosomal small subunit binding	21873635	Function

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Spatial pattern events for Eif1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Eif1	Mouse	Brain	S1	34413515	2.07e-15
Eif1	Mouse	Brain	S2	34413515	1.56e-15
Eif1	Mouse	Brain	S4	34413515	1.37e-15
Eif1	Mouse	Brain	S6	34413515	1.46e-15
Eif1	Mouse	Brain	S7	34413515	1.55e-15
Eif1	Mouse	Brain	05A	32637622	1.02e-10
Eif1	Mouse	Brain	05B	32637622	2.26e-12
Eif1	Mouse	Brain	rep_1	35141374	2.02e-15
Eif1	Mouse	Brain	rep_2	35141374	1.69e-15
Eif1	Mouse	Brain	rep_3	35141374	1.64e-15
Eif1	Mouse	Brain	rep_4	35141374	1.57e-15
Eif1	Mouse	Brain	rep_5	35141374	1.47e-15
Eif1	Mouse	Brain	rep_6	35141374	1.73e-15
Eif1	Mouse	Embryo	rep_4	33188776	2.81e-10
Eif1	Mouse	Embryo	rep_13	33188776	4.49e-15
Eif1	Mouse	Kidney	CLP	34003797	2.19e-15
Eif1	Mouse	Kidney	IRI	34003797	2.29e-15
Eif1	Mouse	Kidney	Sham	34003797	2.58e-15
Eif1	Mouse	Kidney	rep_1	34853151	2.42e-15
Eif1	Mouse	Kidney	rep_2	34853151	6.85e-09
Eif1	Mouse	Kidney	rep_3	34853151	2.94e-15
Eif1	Mouse	Kidney	rep_4	34853151	4.07e-15
Eif1	Mouse	Kidney	rep_5	34853151	3.18e-15
Eif1	Mouse	Kidney	rep_1	33976190	1.85e-06
Eif1	Mouse	Brain	rep_1	33469025	1.30e-15
Eif1	Mouse	Liver	rep_14	35021063	1.90e-13
Eif1	Mouse	Liver	rep_15	35021063	1.57e-07
Eif1	Mouse	Liver	rep_17	35021063	2.18e-14
Eif1	Mouse	Liver	rep_18	35021063	5.67e-07
Eif1	Mouse	Liver	rep_19	35021063	3.50e-14
Eif1	Mouse	Liver	rep_20	35021063	1.65e-14
Eif1	Mouse	Liver	rep_21	35021063	8.03e-15
Eif1	Mouse	Liver	rep_22	35021063	1.07e-14
Eif1	Mouse	Liver	rep_23	35021063	4.20e-14
Eif1	Mouse	Brain	rep_1	35027729	1.66e-15
Eif1	Mouse	Brain	rep_2	35027729	1.57e-15
Eif1	Mouse	Brain	rep_3	35027729	1.32e-15
Eif1	Mouse	Brain	rep_4	35027729	1.76e-15
Eif1	Mouse	Brain	rep_5	35027729	1.46e-15
Eif1	Mouse	Intestine	rep_1	35149721	5.86e-12
Eif1	Mouse	Intestine	rep_2	35149721	6.60e-08
Eif1	Mouse	Intestine	rep_3	35149721	3.25e-15
Eif1	Mouse	Intestine	rep_4	35149721	2.30e-15
Eif1	Mouse	Brain	B05_D2	32702314	2.79e-12
Eif1	Mouse	Brain	B05_E2	32702314	9.99e-11
Eif1	Mouse	Testicle	rep_2	34731600	8.03e-12
Eif1	Mouse	Lymph	A1	0	3.29e-15
Eif1	Mouse	Lymph	B1	0	3.66e-15
Eif1	Mouse	Lung	rep_1	35290801	6.56e-15
Eif1	Mouse	Lung	rep_2	35290801	1.42e-14
Eif1	Mouse	Lung	rep_3	35290801	5.26e-15
Eif1	Mouse	Lung	rep_4	35290801	3.04e-15
Eif1	Mouse	Brain	rep_1	35210624	1.74e-15
Eif1	Mouse	Brain	rep_2	35210624	1.74e-15
Eif1	Mouse	Brain	rep_3	35210624	1.82e-15
Eif1	Mouse	Brain	rep_4	35210624	2.34e-15
Eif1	Mouse	Brain	rep_5	35210624	2.07e-15
Eif1	Mouse	Brain	rep_6	35210624	1.27e-09
Eif1	Mouse	Brain	rep_7	35210624	3.31e-15
Eif1	Mouse	Brain	OFB_adpolb_rep2	33083725	1.35e-02
Eif1	Mouse	Brain	OFB_adpolb_rep3	33083725	7.85e-04
Eif1	Mouse	Brain	OFB_adpolb_rep4	33083725	1.06e-04
Eif1	Mouse	Brain	OFB_adpolb_rep5	33083725	2.44e-04
Eif1	Mouse	Brain	OFB_polb_rep5	33083725	1.98e-03
Eif1	Mouse	Brain	OFB_polb_rep6	33083725	1.62e-02
Eif1	Mouse	Brain	OFB_polb_rep7	33083725	8.97e-06
Eif1	Mouse	Brain	OFB_polb_rep8	33083725	3.53e-03
Eif1	Mouse	Brain	OFB_wt_rep2	33083725	1.91e-03
Eif1	Mouse	Brain	OFB_wt_rep3	33083725	3.05e-05
Eif1	Mouse	Brain	OFB_wt_rep5	33083725	1.08e-02

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Liver_rep_14_H&E
Liver_rep_15_H&E
Liver_rep_17_H&E
Liver_rep_18_H&E
Liver_rep_19_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Liver_rep_23_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E
Brain_OFB_adpolb_rep2_H&E
Brain_OFB_adpolb_rep3_H&E
Brain_OFB_adpolb_rep4_H&E
Brain_OFB_adpolb_rep5_H&E
Brain_OFB_polb_rep5_H&E
Brain_OFB_polb_rep6_H&E
Brain_OFB_polb_rep7_H&E
Brain_OFB_polb_rep8_H&E
Brain_OFB_wt_rep2_H&E
Brain_OFB_wt_rep3_H&E
Brain_OFB_wt_rep5_H&E

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Spatial pattern pathway has Eif1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7CN45_C1	7.4e-09
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Spinal cord	L7CN45_C1	7.9e-07
Eif1	GOBP_Translational_Initiation	Mouse	Spinal cord	L7CN45_C1	1.6e-08
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	rep_3	2.5e-86
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	rep_3	2.1e-69
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	8.5e-206
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	5.2e-187
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Brain	rep_3	1.0e-196
Eif1	GOBP_Translational_Initiation	Mouse	Brain	rep_3	1.2e-197
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Embryo	rep_14	3.7e-18
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Embryo	rep_14	2.8e-15
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Embryo	rep_14	1.4e-11
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	9.9e-25
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Embryo	rep_14	1.2e-21
Eif1	GOBP_Translational_Initiation	Mouse	Embryo	rep_14	1.2e-37
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Kidney	rep_2	2.9e-85
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	1.1e-92
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	9.8e-137
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Kidney	rep_2	3.5e-71
Eif1	GOBP_Translational_Initiation	Mouse	Kidney	rep_2	1.3e-103
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Liver	CN16-D2	6.4e-08
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-09
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Lymph	MS-1	7.1e-07
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	7.1e-09
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-08
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Lymph	MS-1	3.5e-09
Eif1	GOBP_Translational_Initiation	Mouse	Lymph	MS-1	7.5e-07
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Lung	rep_1	1.6e-15
Eif1	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	8.0e-10
Eif1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Eif1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Eif1	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	4.4e-10
Eif1	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Eif1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	1.9e-10
Eif1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-07
Eif1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Brain	HP_ad_rep7	3.8e-08
Eif1	GOBP_Translational_Initiation	Mouse	Brain	HP_ad_rep7	6.9e-08

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Eif1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Eif1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Eif1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Eif1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Eif1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source