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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Suclg2 (spascer ID:20917)

Gene summary for Suclg2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Suclg2
	Gene ID	20917
	Gene name	succinate-Coenzyme A ligase, GDP-forming, beta subunit
	Synonyms	AF171077\|AW556404\|D6Wsu120e\|G-SCS\|GTPSCS\|SCS-betaG
	Cytomap	6 D2\|6 44.63 cM
	Type of gene	protein-coding
	Description	succinate--CoA ligase [GDP-forming] subunit beta, mitochondrialGTP-specific succinyl-CoA synthetase beta subunitsuccinyl-CoA ligase [GDP-forming] subunit beta, mitochondrialsuccinyl-CoA synthetase beta-G chain
	Modification date	20220426
	UniProtAcc	Q9Z2I8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Suclg2	GO:0004776	succinate-CoA ligase (GDP-forming) activity	21873635	Function
Suclg2	GO:0005739	mitochondrion	21873635	Component
Suclg2	GO:0006099	tricarboxylic acid cycle	21873635	Process
Suclg2	GO:0006104	succinyl-CoA metabolic process	21873635	Process
Suclg2	GO:0042709	succinate-CoA ligase complex	21873635	Component

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Spatial pattern events for Suclg2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Suclg2	Mouse	Brain	rep_1	35141374	5.83e-06
Suclg2	Mouse	Brain	rep_2	35141374	1.61e-07
Suclg2	Mouse	Brain	rep_5	35141374	6.96e-08
Suclg2	Mouse	Kidney	CLP	34003797	2.19e-15
Suclg2	Mouse	Kidney	IRI	34003797	2.29e-15
Suclg2	Mouse	Kidney	Sham	34003797	2.58e-15
Suclg2	Mouse	Kidney	rep_1	34853151	2.42e-15
Suclg2	Mouse	Kidney	rep_2	34853151	5.42e-15
Suclg2	Mouse	Kidney	rep_3	34853151	2.94e-15
Suclg2	Mouse	Kidney	rep_4	34853151	4.07e-15
Suclg2	Mouse	Kidney	rep_5	34853151	3.18e-15
Suclg2	Mouse	Brain	rep_1	33469025	8.75e-09
Suclg2	Mouse	Liver	rep_20	35021063	1.29e-06
Suclg2	Mouse	Brain	rep_3	35027729	2.38e-15
Suclg2	Mouse	Brain	rep_5	35027729	3.84e-12
Suclg2	Mouse	Intestine	rep_1	35149721	5.34e-14
Suclg2	Mouse	Intestine	rep_2	35149721	3.44e-15
Suclg2	Mouse	Intestine	rep_3	35149721	1.04e-12
Suclg2	Mouse	Intestine	rep_4	35149721	9.42e-09
Suclg2	Mouse	Testicle	rep_6	34731600	1.33e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_20_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Suclg2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	5.6e-06
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	1.4e-06
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Suclg2	GOBP_Cellular_Respiration	Mouse	Spinal cord	L7CN45_C1	7.0e-07
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Spinal cord	L7CN45_C1	6.8e-07
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Suclg2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Suclg2	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.4e-07
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_11	1.9e-05
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Brain	rep_11	1.5e-05
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Brain	rep_11	1.3e-05
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Brain	rep_11	2.1e-07
Suclg2	GOBP_Aerobic_Respiration	Mouse	Brain	rep_71	1.9e-06
Suclg2	GOBP_Cellular_Respiration	Mouse	Brain	rep_71	1.7e-06
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_71	3.4e-07
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_71	2.1e-06
Suclg2	GOBP_Aerobic_Respiration	Mouse	Brain	rep_1	5.5e-37
Suclg2	GOBP_Cellular_Respiration	Mouse	Brain	rep_1	9.5e-36
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_1	1.1e-29
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_1	5.4e-15
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.2e-146
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Brain	rep_3	6.5e-148
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Brain	rep_3	5.4e-134
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Brain	rep_3	9.1e-46
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	rep_3	1.4e-160
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Brain	rep_3	5.4e-146
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Brain	rep_3	1.7e-102
Suclg2	GOBP_Cellular_Respiration	Mouse	Embryo	rep_6	3.9e-08
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_6	7.1e-08
Suclg2	GOBP_Aerobic_Respiration	Mouse	Embryo	rep_14	4.2e-31
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Embryo	rep_14	2.3e-31
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Embryo	rep_14	2.9e-37
Suclg2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Embryo	rep_14	9.1e-21
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Suclg2	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	6.5e-20
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Embryo	rep_14	4.8e-16
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Embryo	rep_14	2.7e-25
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Embryo	rep_14	5.8e-13
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-17
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Embryo	rep_14	3.5e-21
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	8.2e-31
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Kidney	rep_2	3.3e-14
Suclg2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-39
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Suclg2	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-17
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Kidney	rep_2	3.3e-46
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Kidney	rep_2	1.2e-10
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Kidney	rep_2	8.6e-17
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Kidney	rep_2	6.7e-64
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Kidney	rep_2	2.4e-76
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Liver	CN16-E1	7.0e-07
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Liver	CN16-E1	3.0e-10
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Liver	CN73-C1	2.1e-08
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Liver	CN73-C1	3.0e-07
Suclg2	GOBP_Aerobic_Respiration	Mouse	Liver	rep_16	2.7e-35
Suclg2	GOBP_Cellular_Respiration	Mouse	Liver	rep_16	8.0e-25
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Liver	rep_16	2.0e-28
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Liver	rep_16	7.4e-11
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Intestine	rep_2	6.0e-29
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Intestine	rep_2	2.5e-15
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Intestine	rep_2	2.3e-09
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Intestine	rep_2	7.1e-07
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Intestine	rep_2	7.2e-29
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Suclg2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Suclg2	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	8.0e-08
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Lymph	MS-1	7.8e-10
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Brain	rep_7	8.9e-09
Suclg2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Suclg2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	6.2e-09
Suclg2	GOBP_Nucleoside_Bisphosphate_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.8e-08
Suclg2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Suclg2	GOBP_Thioester_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.7e-10
Suclg2	GOBP_Succinate_Metabolic_Process	Mouse	Brain	HP_ad_rep8	9.2e-08
Suclg2	GOBP_Aerobic_Respiration	Mouse	Brain	HP_polb_rep9	1.4e-09
Suclg2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Suclg2	GOBP_Cellular_Respiration	Mouse	Brain	HP_polb_rep9	2.1e-07
Suclg2	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	HP_polb_rep9	3.0e-10
Suclg2	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	HP_polb_rep9	5.4e-11
Suclg2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Suclg2	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Suclg2	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.4e-07
Suclg2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09
Suclg2	GOBP_Succinyl_Coa_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.1e-08
Suclg2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-08
Suclg2	GOBP_Tricarboxylic_Acid_Cycle	Mouse	Brain	HP_polb_rep9	9.1e-07

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Suclg2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Suclg2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Suclg2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Suclg2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Suclg2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Suclg2	C0014175	Endometriosis	1	CTD_human
Suclg2	C0028754	Obesity	1	CTD_human
Suclg2	C0152013	Adenocarcinoma of lung (disorder)	1	CTD_human
Suclg2	C0268583	Methylmalonic acidemia	1	CTD_human
Suclg2	C0269102	Endometrioma	1	CTD_human
Suclg2	C1855119	Methylmalonic aciduria	1	CTD_human