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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Bhlhe40 (spascer ID:20893)

Gene summary for Bhlhe40

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Bhlhe40

Gene ID

20893

Gene namebasic helix-loop-helix family, member e40
SynonymsBhlhb2|C130042M06Rik|CR8|Clast5|Dec1|Sharp2|Stra13|Stra14
Cytomap6|6 E2
Type of geneprotein-coding
Descriptionclass E basic helix-loop-helix protein 40E47 interaction protein 1basic helix-loop-helix domain containing, class B2class B basic helix-loop-helix protein 2cytokine response gene 8differentially expressed in chondrocytes protein 1eip1 (E47 interacti
Modification date20220426
UniProtAcc

O35185


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Bhlhe40

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
Bhlhe40

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Bhlhe40

GO:0005634

nucleus

21873635

Component
Bhlhe40

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process
Bhlhe40

GO:0009952

anterior/posterior pattern specification

21873635

Process
Bhlhe40

GO:0032922

circadian regulation of gene expression

21873635

Process
Bhlhe40

GO:0050767

regulation of neurogenesis

21873635

Process

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Spatial pattern events for Bhlhe40

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Bhlhe40MouseBrainS1 344135152.07e-15
Bhlhe40MouseBrainS2 344135151.56e-15
Bhlhe40MouseBrainS3 344135151.64e-15
Bhlhe40MouseBrainS4 344135151.37e-15
Bhlhe40MouseBrainS6 344135151.46e-15
Bhlhe40MouseBrainS7 344135151.55e-15
Bhlhe40MouseBrain02A 326376224.93e-08
Bhlhe40MouseBrain02B 326376221.01e-06
Bhlhe40MouseBrain04A 326376222.59e-06
Bhlhe40MouseBrain04B 326376223.34e-08
Bhlhe40MouseBrain05A 326376221.40e-10
Bhlhe40MouseBrain05B 326376221.16e-09
Bhlhe40MouseBrain06A 326376225.77e-07
Bhlhe40MouseBrain06B 326376221.68e-14
Bhlhe40MouseBrain07A 326376224.53e-08
Bhlhe40MouseBrain07B 326376223.64e-11
Bhlhe40MouseBrain08A 326376221.70e-06
Bhlhe40MouseBrain08B 326376228.68e-08
Bhlhe40MouseBrain09A 326376227.97e-07
Bhlhe40MouseBrain09B 326376221.87e-10
Bhlhe40MouseBrain11A 326376221.89e-11
Bhlhe40MouseBrain12B 326376222.01e-14
Bhlhe40MouseBrain13B 326376222.49e-06
Bhlhe40MouseBrain14A 326376224.13e-14
Bhlhe40MouseBrain14B 326376225.10e-11
Bhlhe40MouseBrain15A 326376224.45e-09
Bhlhe40MouseBrain15B 326376227.69e-10
Bhlhe40MouseBrain17A 326376222.90e-09
Bhlhe40MouseBrain17B 326376221.31e-07
Bhlhe40MouseBrain18B 326376225.36e-07
Bhlhe40MouseBrain21A 326376228.33e-06
Bhlhe40MouseBrain21B 326376223.84e-07
Bhlhe40MouseBrain22A 326376221.17e-08
Bhlhe40MouseBrain22B 326376221.95e-07
Bhlhe40MouseBrain23B 326376221.67e-11
Bhlhe40MouseBrain24A 326376222.74e-06
Bhlhe40MouseBrain24B 326376222.92e-10
Bhlhe40MouseBrain25A 326376222.91e-14
Bhlhe40MouseBrain26A 326376225.88e-08
Bhlhe40MouseBrain27A 326376225.98e-08
Bhlhe40MouseBrain27B 326376223.57e-10
Bhlhe40MouseBrain28A 326376221.35e-11
Bhlhe40MouseBrain28B 326376223.65e-08
Bhlhe40MouseBrain29A 326376221.08e-14
Bhlhe40MouseBrain29B 326376221.08e-14
Bhlhe40MouseBrain30A 326376221.34e-09
Bhlhe40MouseBrain31A 326376224.69e-10
Bhlhe40MouseBrain32A 326376227.01e-10
Bhlhe40MouseBrain33A 326376221.50e-14
Bhlhe40MouseBrain33B 326376223.35e-14
Bhlhe40MouseBrain34A 326376221.34e-11
Bhlhe40MouseBrain34B 326376222.06e-12
Bhlhe40MouseBrain35A 326376221.48e-14
Bhlhe40MouseBrain35B 326376222.33e-13
Bhlhe40MouseBrainrep_1 351413742.02e-15
Bhlhe40MouseBrainrep_2 351413741.69e-15
Bhlhe40MouseBrainrep_3 351413741.64e-15
Bhlhe40MouseBrainrep_4 351413741.57e-15
Bhlhe40MouseBrainrep_5 351413741.47e-15
Bhlhe40MouseBrainrep_6 351413741.73e-15
Bhlhe40MouseKidneyCLP 340037972.19e-15
Bhlhe40MouseKidneyIRI 340037972.29e-15
Bhlhe40MouseKidneyrep_2 348531515.97e-13
Bhlhe40MouseKidneyrep_4 348531514.07e-15
Bhlhe40MouseKidneyrep_5 348531513.18e-15
Bhlhe40MouseBrainrep_1 334690251.24e-06
Bhlhe40MouseLiverrep_19 350210631.61e-07
Bhlhe40MouseBrainrep_1 350277291.66e-15
Bhlhe40MouseBrainrep_2 350277291.57e-15
Bhlhe40MouseBrainrep_3 350277291.32e-15
Bhlhe40MouseBrainrep_4 350277291.76e-15
Bhlhe40MouseBrainrep_5 350277291.46e-15
Bhlhe40MouseIntestinerep_1 351497214.15e-07
Bhlhe40MouseIntestinerep_2 351497213.44e-15
Bhlhe40MouseIntestinerep_3 351497213.25e-15
Bhlhe40MouseIntestinerep_4 351497211.19e-10
Bhlhe40MouseBrainB02_E1 327023142.32e-06
Bhlhe40MouseBrainB04_D1 327023146.78e-07
Bhlhe40MouseBrainB04_E1 327023143.32e-13
Bhlhe40MouseBrainB05_D2 327023142.58e-06
Bhlhe40MouseLymphA1 03.29e-15
Bhlhe40MouseLymphB1 03.66e-15
Bhlhe40MouseLungrep_1 352908016.56e-15
Bhlhe40MouseLungrep_2 352908016.93e-14
Bhlhe40MouseLungrep_4 352908011.02e-14
Bhlhe40MouseBrainrep_1 352106241.74e-15
Bhlhe40MouseBrainrep_2 352106241.74e-15
Bhlhe40MouseBrainrep_3 352106241.82e-15
Bhlhe40MouseBrainrep_5 352106243.69e-11
Bhlhe40MouseBrainrep_6 352106246.92e-15
Bhlhe40MouseBrainrep_7 352106241.87e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_rep_2_H&E
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Kidney_rep_4_H&E
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Kidney_rep_5_H&E
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Brain_rep_1_H&E
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Liver_rep_19_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_E1_H&E
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Brain_B04_D1_H&E
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Brain_B04_E1_H&E
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Brain_B05_D2_H&E
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Lung_rep_1_H&E
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Lung_rep_2_H&E
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Lung_rep_4_H&E
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Spatial pattern pathway has Bhlhe40 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseSpinal cordCN94_E1 4.9e-06
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseSpinal cordCN94_E1 1.6e-06
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseSpinal cordCN94_E1 6.2e-07
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseSpinal cordCN94_E1 2.2e-06
Bhlhe40GOBP_RegionalizationMouseSpinal cordCN94_E1 7.3e-06
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseSpinal cordCN94_E1 1.2e-06
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseSpinal cordCN94_E1 6.7e-06
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseSpinal cordCN94_E1 4.5e-06
Bhlhe40GOBP_Circadian_RhythmMouseSpinal cordL7bCN02_E1 4.0e-06
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseSpinal cordL7CN45_C1 1.1e-06
Bhlhe40GOBP_NeurogenesisMouseSpinal cordL7CN45_C1 3.4e-09
Bhlhe40GOBP_Pattern_Specification_ProcessMouseSpinal cordL7CN45_C1 2.2e-09
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseSpinal cordL7CN45_C1 8.5e-07
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseSpinal cordL7CN45_C1 4.0e-08
Bhlhe40GOBP_Response_To_RadiationMouseSpinal cordL7CN45_C1 4.5e-07
Bhlhe40GOBP_Rhythmic_ProcessMouseSpinal cordL7CN45_C1 1.9e-06
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseSpinal cordL7CN47_C1 1.2e-07
Bhlhe40GOBP_Response_To_Light_StimulusMouseSpinal cordL7CN47_C1 3.8e-06
Bhlhe40GOBP_PhotoperiodismMouseSpinal cordL7CN85_E2 2.2e-06
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseSpinal cordL8CN17_E1 2.7e-06
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseBrainrep_27 3.1e-05
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseBrainrep_27 7.2e-05
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseBrainrep_27 2.8e-05
Bhlhe40GOBP_Pattern_Specification_ProcessMouseBrainrep_27 3.2e-09
Bhlhe40GOBP_RegionalizationMouseBrainrep_27 3.9e-08
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseBrainrep_27 5.5e-05
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseBrainrep_72 3.3e-05
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseBrainrep_1 3.1e-14
Bhlhe40GOBP_Circadian_RhythmMouseBrainrep_1 2.6e-25
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseBrainrep_1 6.5e-19
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseBrainrep_1 1.0e-08
Bhlhe40GOBP_NeurogenesisMouseBrainrep_1 6.4e-19
Bhlhe40GOBP_PhotoperiodismMouseBrainrep_1 3.4e-12
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseBrainrep_1 5.8e-13
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseBrainrep_1 2.3e-15
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseBrainrep_1 1.6e-27
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseBrainrep_1 1.1e-12
Bhlhe40GOBP_Response_To_Abiotic_StimulusMouseBrainrep_1 6.0e-28
Bhlhe40GOBP_Rhythmic_ProcessMouseBrainrep_1 4.6e-47
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseBrainrep_31.2e-140
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseBrainrep_31.4e-196
Bhlhe40GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseBrainrep_3 4.3e-75
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseBrainrep_39.4e-206
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseBrainrep_37.5e-168
Bhlhe40GOBP_Pattern_Specification_ProcessMouseBrainrep_31.6e-118
Bhlhe40GOBP_RegionalizationMouseBrainrep_31.3e-180
Bhlhe40GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseBrainrep_31.8e-138
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseBrainrep_3 5.2e-95
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseBrainrep_3 3.7e-35
Bhlhe40GOBP_Response_To_Light_StimulusMouseBrainrep_3 3.8e-27
Bhlhe40GOBP_Response_To_RadiationMouseBrainrep_3 4.6e-08
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseEmbryorep_6 1.5e-09
Bhlhe40GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseEmbryorep_6 1.4e-07
Bhlhe40GOBP_Circadian_RhythmMouseEmbryorep_14 5.3e-08
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseEmbryorep_14 6.4e-41
Bhlhe40GOBP_PhotoperiodismMouseEmbryorep_14 6.4e-64
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseEmbryorep_14 4.4e-17
Bhlhe40GOBP_NeurogenesisMouseEmbryorep_1 8.2e-08
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseEmbryorep_1 3.5e-55
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseEmbryorep_12.8e-203
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseEmbryorep_1 2.3e-08
Bhlhe40GOBP_Response_To_Light_StimulusMouseEmbryorep_11.5e-185
Bhlhe40GOBP_Response_To_RadiationMouseEmbryorep_1 0.0e+00
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseEmbryorep_28.6e-166
Bhlhe40GOBP_Circadian_RhythmMouseEmbryorep_2 5.3e-10
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseEmbryorep_2 8.0e-13
Bhlhe40GOBP_RegionalizationMouseEmbryorep_2 5.4e-84
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseEmbryorep_21.1e-224
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseEmbryorep_2 3.0e-74
Bhlhe40GOBP_Rhythmic_ProcessMouseEmbryorep_27.6e-139
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseEmbryorep_31.5e-267
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseEmbryorep_3 0.0e+00
Bhlhe40GOBP_Pattern_Specification_ProcessMouseEmbryorep_32.8e-168
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseEmbryorep_3 6.3e-72
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseKidneyNep 8.3e-23
Bhlhe40GOBP_NeurogenesisMouseKidneyNep 4.6e-22
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseKidneyNep 1.3e-32
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseKidneyrep_2 3.0e-23
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseKidneyrep_2 6.4e-21
Bhlhe40GOBP_Circadian_RhythmMouseKidneyrep_2 1.8e-75
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseKidneyrep_2 2.4e-86
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseKidneyrep_2 7.3e-42
Bhlhe40GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseKidneyrep_2 3.3e-62
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseKidneyrep_2 2.5e-99
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseKidneyrep_2 7.7e-30
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseKidneyrep_2 2.2e-14
Bhlhe40GOBP_NeurogenesisMouseKidneyrep_2 2.4e-78
Bhlhe40GOBP_Pattern_Specification_ProcessMouseKidneyrep_2 2.3e-36
Bhlhe40GOBP_PhotoperiodismMouseKidneyrep_2 1.3e-53
Bhlhe40GOBP_RegionalizationMouseKidneyrep_2 2.1e-25
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseKidneyrep_2 5.3e-55
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseKidneyrep_2 2.6e-14
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseKidneyrep_2 2.9e-35
Bhlhe40GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseKidneyrep_2 2.6e-30
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseKidneyrep_28.2e-110
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseKidneyrep_2 3.8e-54
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseKidneyrep_2 6.9e-62
Bhlhe40GOBP_Response_To_Light_StimulusMouseKidneyrep_2 4.7e-16
Bhlhe40GOBP_Rhythmic_ProcessMouseKidneyrep_2 4.7e-69
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseLiverCN73-C1 9.9e-07
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseLiverrep_15 6.6e-15
Bhlhe40GOBP_PhotoperiodismMouseLiverrep_15 5.7e-18
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseLiverrep_16 7.9e-10
Bhlhe40GOBP_Circadian_RhythmMouseLiverrep_16 4.6e-09
Bhlhe40GOBP_Pattern_Specification_ProcessMouseLiverrep_16 3.6e-20
Bhlhe40GOBP_RegionalizationMouseLiverrep_16 1.2e-11
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseLiverrep_16 3.6e-08
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseLymphMS-1 9.9e-08
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseLymphMS-1 6.1e-11
Bhlhe40GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseLymphMS-1 3.0e-08
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseLymphMS-1 6.9e-11
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseLymphMS-1 1.8e-10
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseLymphMS-1 2.2e-09
Bhlhe40GOBP_NeurogenesisMouseLymphMS-1 4.1e-08
Bhlhe40GOBP_Pattern_Specification_ProcessMouseLymphMS-1 3.9e-12
Bhlhe40GOBP_PhotoperiodismMouseLymphMS-1 1.0e-09
Bhlhe40GOBP_RegionalizationMouseLymphMS-1 2.7e-12
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseLymphMS-1 2.7e-13
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseLymphMS-1 1.3e-14
Bhlhe40GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseLymphMS-1 8.0e-12
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseLymphMS-1 7.2e-15
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseLymphMS-1 4.3e-11
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseLymphMS-1 4.3e-11
Bhlhe40GOBP_Response_To_Abiotic_StimulusMouseLymphMS-1 1.5e-07
Bhlhe40GOBP_Response_To_Light_StimulusMouseLymphMS-1 3.8e-09
Bhlhe40GOBP_Response_To_RadiationMouseLymphMS-1 9.1e-12
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseLungrep_1 7.5e-20
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseLungrep_1 9.4e-15
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseLungrep_1 5.8e-10
Bhlhe40GOBP_Circadian_RhythmMouseBrainrep_4 2.1e-77
Bhlhe40GOBP_RegionalizationMouseBrainrep_4 6.3e-07
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseBrainrep_4 6.3e-75
Bhlhe40GOBP_Rhythmic_ProcessMouseBrainrep_4 3.3e-35
Bhlhe40GOBP_Pattern_Specification_ProcessMouseBrainrep_7 1.0e-12
Bhlhe40GOBP_Circadian_Regulation_Of_Gene_ExpressionMouseBrainHP_ad_rep7 1.2e-07
Bhlhe40GOBP_Circadian_RhythmMouseBrainHP_ad_rep7 4.9e-12
Bhlhe40GOBP_Entrainment_Of_Circadian_ClockMouseBrainHP_ad_rep7 4.4e-07
Bhlhe40GOBP_Negative_Regulation_Of_Biosynthetic_ProcessMouseBrainHP_ad_rep7 3.3e-12
Bhlhe40GOBP_Negative_Regulation_Of_Molecular_FunctionMouseBrainHP_ad_rep7 3.4e-10
Bhlhe40GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseBrainHP_ad_rep7 5.9e-11
Bhlhe40GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseBrainHP_ad_rep7 7.1e-13
Bhlhe40GOBP_NeurogenesisMouseBrainHP_ad_rep7 3.9e-07
Bhlhe40GOBP_Pattern_Specification_ProcessMouseBrainHP_ad_rep7 2.1e-10
Bhlhe40GOBP_PhotoperiodismMouseBrainHP_ad_rep7 4.1e-08
Bhlhe40GOBP_RegionalizationMouseBrainHP_ad_rep7 2.8e-09
Bhlhe40GOBP_Regulation_Of_Cell_DevelopmentMouseBrainHP_ad_rep7 3.8e-09
Bhlhe40GOBP_Regulation_Of_Multicellular_Organismal_DevelopmentMouseBrainHP_ad_rep7 1.1e-08
Bhlhe40GOBP_Regulation_Of_Nervous_System_DevelopmentMouseBrainHP_ad_rep7 1.1e-07
Bhlhe40GOBP_Regulation_Of_NeurogenesisMouseBrainHP_ad_rep7 1.1e-08
Bhlhe40GOBP_Response_To_Abiotic_StimulusMouseBrainHP_ad_rep7 4.3e-08
Bhlhe40GOBP_Response_To_Light_StimulusMouseBrainHP_ad_rep7 1.6e-09
Bhlhe40GOBP_Response_To_RadiationMouseBrainHP_ad_rep7 9.1e-09
Bhlhe40GOBP_Rhythmic_ProcessMouseBrainHP_ad_rep7 4.3e-13
Bhlhe40GOBP_Anterior_Posterior_Pattern_SpecificationMouseBrainHP_adpolb_rep1 3.0e-08
Bhlhe40GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseBrainHP_polb_rep9 2.1e-11
Bhlhe40GOBP_Regulation_Of_Cell_DifferentiationMouseBrainHP_polb_rep9 6.5e-09
Bhlhe40GOBP_Regulation_Of_Circadian_RhythmMouseBrainHP_polb_rep9 1.8e-10
Bhlhe40GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityMouseBrainHP_polb_rep9 7.0e-08

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Bhlhe40 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Bhlhe40 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Bhlhe40 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score
Bhlhe40KidneyLPSPT_S3_OSCaskin2,Hacd4,Klf13, etc.0.296
Bhlhe40KidneyLPSTALCaskin2,Hacd4,Klf13, etc.0.348
Bhlhe40KidneyLPSCNTCaskin2,Hacd4,Klf13, etc.0.261
Bhlhe40KidneyLPSPT_S2Caskin2,Hacd4,Klf13, etc.0.263
Bhlhe40KidneyLPSPT_S3_CCaskin2,Hacd4,Klf13, etc.0.314
Bhlhe40LiverWD_36weekEndothelialTraf1,Etv3,Aebp2, etc.0.257
Bhlhe40LiverWD_36weekKCTraf1,Etv3,Aebp2, etc.0.301
Bhlhe40LiverWD_36weekUnclearTraf1,Etv3,Aebp2, etc.0.265
Bhlhe40LiverWD_36weekMonocyteTraf1,Etv3,Aebp2, etc.0.396
Bhlhe40LiverWD_36weekT cellsTraf1,Etv3,Aebp2, etc.0.286
BHLHE40IntestinedevelopmentEndotheliumKLF6,DDIT3,CXCL2, etc.0.273
BHLHE40IntestinedevelopmentEpitheliumKLF6,DDIT3,CXCL2, etc.0.429
BHLHE40IntestinedevelopmentFibroblastsKLF6,DDIT3,CXCL2, etc.0.407
BHLHE40IntestinedevelopmentMyoFibroblastsKLF6,DDIT3,CXCL2, etc.0.273
Bhlhe40LymphcontrolIfit3 high BTnfaip3,Cdk5r1,Cd274, etc.0.274
Bhlhe40LymphcontrolMature BTnfaip3,Cdk5r1,Cd274, etc.0.383
Bhlhe40LiverSD_36weekEndothelialDusp5,Xcl1,Ccnd2, etc.0.458
Bhlhe40LiverSD_36weekKCDusp5,Xcl1,Ccnd2, etc.0.311
Bhlhe40LiverSD_36weekUnclearDusp5,Xcl1,Ccnd2, etc.0.259
Bhlhe40LiverSD_36weekMonocyteDusp5,Xcl1,Ccnd2, etc.0.258
Bhlhe40KidneyIRIPT_S1Tsc22d1,Cryab,S100a10, etc.0.315
Bhlhe40KidneyIRIPT_S3_CTsc22d1,Cryab,S100a10, etc.0.297
Bhlhe40KidneyIRIPT_FibrinogenTsc22d1,Cryab,S100a10, etc.0.292
Bhlhe40KidneyIRITALTsc22d1,Cryab,S100a10, etc.0.285
Bhlhe40KidneyIRIPT_S3_OSTsc22d1,Cryab,S100a10, etc.0.252
Bhlhe40KidneyIRICD_PCTsc22d1,Cryab,S100a10, etc.0.262
Bhlhe40LiverSD_24weekKCBcl2a1d,Avpi1,AA467197, etc.0.296
Bhlhe40LiverSD_24weekMonocyteBcl2a1d,Avpi1,AA467197, etc.0.332
Bhlhe40LiverSD_24weekcDC1Bcl2a1d,Avpi1,AA467197, etc.0.285
Bhlhe40LiverSD_24weekpDCsBcl2a1d,Avpi1,AA467197, etc.0.278
Bhlhe40LiverSD_24weekTcellBcl2a1d,Avpi1,AA467197, etc.0.259
Bhlhe40LiverSD_24weekUnknownBcl2a1d,Avpi1,AA467197, etc.0.281
Bhlhe40LiverSD_24weekEndothelial Bcl2a1d,Avpi1,AA467197, etc.0.261
Bhlhe40LymphdiseaseIfit3 high BTnfaip3,Nfkbia,Kdr, etc.0.312
Bhlhe40LymphdiseaseCD4 TTnfaip3,Nfkbia,Kdr, etc.0.253
Bhlhe40LymphdiseaseMature BTnfaip3,Nfkbia,Kdr, etc.0.354
Bhlhe40LiverSD_12weekMonocyteTraf1,Bcl2a1b,Jak2, etc.0.373
Bhlhe40LiverSD_12weekpDCsTraf1,Bcl2a1b,Jak2, etc.0.266
Bhlhe40LiverSD_12weekcDC1Traf1,Bcl2a1b,Jak2, etc.0.259
Bhlhe40LiverSD_12weekT cellsTraf1,Bcl2a1b,Jak2, etc.0.251
Bhlhe40LiverSD_12weekEndothelialTraf1,Bcl2a1b,Jak2, etc.0.279
Bhlhe40LiverSD_12weekcDC2Traf1,Bcl2a1b,Jak2, etc.0.272
Bhlhe40LiverSD_12weekKCTraf1,Bcl2a1b,Jak2, etc.0.371

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Related Drugs for Bhlhe40

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Bhlhe40

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Bhlhe40C0005586Bipolar Disorder3CTD_human;PSYGENET
Bhlhe40C0005587Depression, Bipolar1CTD_human
Bhlhe40C0017636Glioblastoma1CTD_human
Bhlhe40C0024713Manic Disorder1CTD_human
Bhlhe40C0036341Schizophrenia1PSYGENET
Bhlhe40C0151744Myocardial Ischemia1CTD_human
Bhlhe40C0334588Giant Cell Glioblastoma1CTD_human
Bhlhe40C0338831Manic1CTD_human
Bhlhe40C0393770Delayed Sleep Phase Syndrome1CTD_human
Bhlhe40C0494410Nonorganic Sleep Wake Cycle Disorders1CTD_human
Bhlhe40C0751758Advanced Sleep Phase Syndrome1CTD_human
Bhlhe40C0751759Non-24 Hour Sleep-Wake Disorder1CTD_human
Bhlhe40C0751760Shift-Work Sleep Disorder1CTD_human
Bhlhe40C0877792Sleep Disorders, Circadian Rhythm1CTD_human
Bhlhe40C1621958Glioblastoma Multiforme1CTD_human