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Spatial pattern gene: Stip1 (spascer ID:20867) |
Gene summary for Stip1 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Stip1 | Gene ID | 20867 |
| Gene name | stress-induced phosphoprotein 1 |
| Synonyms | Hop|Sti1|p60 |
| Cytomap | 19|19 A |
| Type of gene | protein-coding |
| Description | stress-induced-phosphoprotein 1Hsp70/Hsp90 organizing proteinIEF SSP 3521hsc70/Hsp90-organizing proteinmSTI1stress-inducible protein |
| Modification date | 20220424 |
| UniProtAcc | Q60864 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Stip1 | GO:0051879 | Hsp90 protein binding | 21873635 | Function |
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Spatial pattern events for Stip1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Stip1 | Mouse | Brain | S1 | 34413515 | 6.04e-11 |
| Stip1 | Mouse | Brain | S2 | 34413515 | 2.77e-12 |
| Stip1 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Stip1 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Stip1 | Mouse | Brain | S6 | 34413515 | 4.41e-09 |
| Stip1 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Stip1 | Mouse | Brain | 33A | 32637622 | 2.70e-08 |
| Stip1 | Mouse | Brain | rep_1 | 35141374 | 1.57e-13 |
| Stip1 | Mouse | Brain | rep_2 | 35141374 | 9.97e-09 |
| Stip1 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Stip1 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Stip1 | Mouse | Brain | rep_5 | 35141374 | 5.13e-15 |
| Stip1 | Mouse | Brain | rep_6 | 35141374 | 2.94e-11 |
| Stip1 | Mouse | Embryo | rep_3 | 33188776 | 6.04e-07 |
| Stip1 | Mouse | Embryo | rep_12 | 33188776 | 9.82e-08 |
| Stip1 | Mouse | Embryo | rep_13 | 33188776 | 2.31e-07 |
| Stip1 | Mouse | Kidney | CLP | 34003797 | 3.77e-15 |
| Stip1 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Stip1 | Mouse | Kidney | Sham | 34003797 | 4.30e-15 |
| Stip1 | Mouse | Kidney | rep_1 | 34853151 | 8.03e-13 |
| Stip1 | Mouse | Kidney | rep_3 | 34853151 | 4.16e-10 |
| Stip1 | Mouse | Kidney | rep_5 | 34853151 | 1.14e-11 |
| Stip1 | Mouse | Brain | rep_1 | 33469025 | 2.00e-08 |
| Stip1 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Stip1 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Stip1 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Stip1 | Mouse | Brain | rep_4 | 35027729 | 2.15e-10 |
| Stip1 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Stip1 | Mouse | Lymph | B1 | 0 | 3.04e-08 |
| Stip1 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Stip1 | Mouse | Lung | rep_2 | 35290801 | 2.86e-08 |
| Stip1 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Stip1 | Mouse | Brain | rep_2 | 35210624 | 4.06e-06 |
| Stip1 | Mouse | Brain | rep_3 | 35210624 | 1.25e-14 |
| Stip1 | Mouse | Brain | rep_4 | 35210624 | 5.75e-11 |
| Stip1 | Mouse | Brain | rep_6 | 35210624 | 2.05e-15 |
| Stip1 | Mouse | Brain | rep_7 | 35210624 | 9.41e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
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Spatial pattern pathway has Stip1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Spinal cord | L7CN45_C1 | 8.0e-07 |
| Stip1 | GOBP_Response_To_Interleukin_7 | Mouse | Spinal cord | L7CN45_C1 | 1.9e-07 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Brain | rep_3 | 1.2e-08 |
| Stip1 | GOBP_Response_To_Interleukin_7 | Mouse | Brain | rep_3 | 2.7e-132 |
| Stip1 | GOBP_Response_To_Interleukin_7 | Mouse | Embryo | rep_14 | 6.1e-07 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Embryo | rep_1 | 8.2e-211 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Kidney | rep_2 | 3.1e-14 |
| Stip1 | GOBP_Response_To_Interleukin_7 | Mouse | Kidney | rep_2 | 1.9e-25 |
| Stip1 | GOBP_Response_To_Interleukin_7 | Mouse | Liver | CN16-D2 | 2.4e-07 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Liver | rep_16 | 1.4e-13 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Lymph | MS-1 | 5.7e-15 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Lung | rep_1 | 1.2e-17 |
| Stip1 | GOBP_Response_To_Cytokine | Mouse | Brain | HP_ad_rep7 | 2.1e-08 |
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Stip1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Stip1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Stip1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Stip1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Stip1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Stip1 | C0011581 | Depressive disorder | 1 | PSYGENET |
| Stip1 | C0025202 | melanoma | 1 | CTD_human |
