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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Stat6 (spascer ID:20852)

Gene summary for Stat6

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Stat6

Gene ID

20852

Gene namesignal transducer and activator of transcription 6
Synonyms-
Cytomap10 D3|10 74.59 cM
Type of geneprotein-coding
Descriptionsignal transducer and transcription activator 6
Modification date20220510
UniProtAcc

P52633


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Stat6

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
Stat6

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Stat6

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process
Stat6

GO:0006952

defense response

21873635

Process
Stat6

GO:0007259

receptor signaling pathway via JAK-STAT

21873635

Process
Stat6

GO:0019221

cytokine-mediated signaling pathway

21873635

Process
Stat6

GO:0042127

regulation of cell population proliferation

21873635

Process
Stat6

GO:0043434

response to peptide hormone

21873635

Process
Stat6

GO:0060397

growth hormone receptor signaling pathway via JAK-STAT

21873635

Process

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Spatial pattern events for Stat6

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Stat6MouseBrainS4 344135151.39e-06
Stat6MouseBrainrep_4 351413745.40e-10
Stat6MouseKidneyCLP 340037976.92e-15
Stat6MouseBrainrep_5 350277292.70e-08
Stat6MouseTesticlerep_4 347316001.61e-14

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_4_H&E
boxplot
boxplot
Kidney_CLP_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot


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Spatial pattern pathway has Stat6 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseSpinal cordCN94_E1 4.1e-07
Stat6GOBP_Cellular_Response_To_PeptideMouseSpinal cordCN94_E1 7.7e-06
Stat6GOBP_Cytokine_Mediated_Signaling_PathwayMouseSpinal cordCN94_E1 3.0e-06
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseSpinal cordCN94_E1 4.4e-07
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseSpinal cordCN94_E1 6.4e-06
Stat6GOBP_Response_To_Endogenous_StimulusMouseSpinal cordCN94_E1 2.2e-06
Stat6GOBP_Response_To_HormoneMouseSpinal cordCN94_E1 4.8e-06
Stat6GOBP_Response_To_Interleukin_4MouseSpinal cordCN94_E1 7.2e-06
Stat6GOBP_Response_To_Nitrogen_CompoundMouseSpinal cordCN94_E1 5.6e-06
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseSpinal cordL7bCN02_E1 7.5e-06
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseSpinal cordL7CN40_C1 7.3e-07
Stat6GOBP_Adaptive_ThermogenesisMouseSpinal cordL7CN45_C1 4.5e-09
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseSpinal cordL7CN45_C1 2.4e-08
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 1.6e-07
Stat6GOBP_Cellular_Response_To_Peptide_Hormone_StimulusMouseSpinal cordL7CN45_C1 2.8e-06
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseSpinal cordL7CN45_C1 8.7e-08
Stat6GOBP_Homeostatic_ProcessMouseSpinal cordL7CN45_C1 3.4e-09
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseSpinal cordL7CN45_C1 3.5e-09
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseSpinal cordL7CN45_C1 7.2e-09
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseSpinal cordL7CN45_C1 6.3e-07
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseSpinal cordL7CN45_C1 1.4e-06
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseSpinal cordL7CN45_C1 5.0e-08
Stat6GOBP_Response_To_CytokineMouseSpinal cordL7CN45_C1 8.0e-07
Stat6GOBP_Response_To_Growth_HormoneMouseSpinal cordL7CN45_C1 1.2e-08
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 8.5e-07
Stat6GOBP_Response_To_PeptideMouseSpinal cordL7CN45_C1 8.5e-07
Stat6GOBP_Response_To_Peptide_HormoneMouseSpinal cordL7CN45_C1 2.8e-06
Stat6GOBP_Temperature_HomeostasisMouseSpinal cordL7CN45_C1 8.7e-08
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseSpinal cordL7CN45_C1 5.7e-08
Stat6GOBP_Cytokine_ProductionMouseSpinal cordL7CN80_D2 4.5e-06
Stat6GOBP_Defense_ResponseMouseSpinal cordL8CN11_C1 3.3e-17
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseBrainrep_27 8.3e-05
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseBrainrep_36 6.7e-06
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseBrainrep_70 7.7e-06
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseBrainrep_74 2.6e-06
Stat6GOBP_Response_To_Growth_HormoneMouseBrainrep_75 4.2e-05
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseBrainrep_1 1.3e-42
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseBrainrep_1 1.5e-10
Stat6GOBP_Cellular_Response_To_PeptideMouseBrainrep_1 4.2e-07
Stat6GOBP_Cellular_Response_To_Peptide_Hormone_StimulusMouseBrainrep_1 3.6e-07
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainrep_1 9.9e-07
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseBrainrep_1 2.9e-26
Stat6GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseBrainrep_1 2.5e-12
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseBrainrep_1 1.6e-17
Stat6GOBP_Receptor_Signaling_Pathway_Via_StatMouseBrainrep_1 2.0e-25
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainrep_1 8.6e-14
Stat6GOBP_Type_I_Interferon_ProductionMouseBrainrep_1 1.5e-07
Stat6GOBP_Cellular_Response_To_Hormone_StimulusMouseBrainrep_3 4.3e-99
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 8.2e-81
Stat6GOBP_Cytokine_Mediated_Signaling_PathwayMouseBrainrep_3 4.9e-10
Stat6GOBP_Cytokine_ProductionMouseBrainrep_3 6.3e-65
Stat6GOBP_Defense_ResponseMouseBrainrep_3 8.7e-77
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseBrainrep_3 3.8e-08
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseBrainrep_3 6.7e-70
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseBrainrep_3 7.5e-78
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseBrainrep_33.1e-102
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseBrainrep_33.5e-105
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseBrainrep_35.5e-105
Stat6GOBP_Response_To_CytokineMouseBrainrep_3 1.2e-08
Stat6GOBP_Response_To_Endogenous_StimulusMouseBrainrep_3 6.4e-96
Stat6GOBP_Response_To_Growth_HormoneMouseBrainrep_3 7.3e-70
Stat6GOBP_Response_To_HormoneMouseBrainrep_38.1e-134
Stat6GOBP_Response_To_Interleukin_4MouseBrainrep_3 1.0e-18
Stat6GOBP_Response_To_Nitrogen_CompoundMouseBrainrep_3 2.5e-82
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 6.3e-92
Stat6GOBP_Response_To_PeptideMouseBrainrep_3 1.8e-28
Stat6GOBP_Response_To_Peptide_HormoneMouseBrainrep_4 7.7e-16
Stat6GOBP_Temperature_HomeostasisMouseBrainrep_4 9.5e-07
Stat6GOBP_Adaptive_ThermogenesisMouseBrainrep_7 2.9e-65
Stat6GOBP_Homeostatic_ProcessMouseBrainrep_7 2.5e-13
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseEmbryorep_6 6.3e-07
Stat6GOBP_Adaptive_ThermogenesisMouseEmbryorep_14 2.8e-18
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseEmbryorep_14 2.4e-24
Stat6GOBP_Cytokine_ProductionMouseEmbryorep_14 1.9e-09
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseEmbryorep_14 4.9e-41
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseEmbryorep_14 1.4e-13
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseEmbryorep_14 4.1e-16
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseEmbryorep_14 5.7e-46
Stat6GOBP_Response_To_Growth_HormoneMouseEmbryorep_14 1.3e-19
Stat6GOBP_Response_To_Interleukin_4MouseEmbryorep_14 3.0e-10
Stat6GOBP_Temperature_HomeostasisMouseEmbryorep_14 4.5e-07
Stat6GOBP_Type_I_Interferon_ProductionMouseEmbryorep_14 3.8e-21
Stat6GOBP_Adaptive_ThermogenesisMouseEmbryorep_1 0.0e+00
Stat6GOBP_Cellular_Response_To_Hormone_StimulusMouseEmbryorep_1 3.9e-07
Stat6GOBP_Defense_ResponseMouseEmbryorep_1 5.2e-63
Stat6GOBP_Homeostatic_ProcessMouseEmbryorep_1 2.0e-30
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseEmbryorep_1 7.9e-50
Stat6GOBP_Receptor_Signaling_Pathway_Via_StatMouseEmbryorep_1 0.0e+00
Stat6GOBP_Response_To_CytokineMouseEmbryorep_18.2e-211
Stat6GOBP_Response_To_PeptideMouseEmbryorep_1 5.6e-22
Stat6GOBP_Temperature_HomeostasisMouseEmbryorep_1 0.0e+00
Stat6GOBP_Response_To_Interleukin_4MouseEmbryorep_2 0.0e+00
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseEmbryorep_3 0.0e+00
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseEmbryorep_3 0.0e+00
Stat6GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseEmbryorep_3 0.0e+00
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseEmbryorep_3 0.0e+00
Stat6GOBP_Response_To_Growth_HormoneMouseEmbryorep_3 4.7e-07
Stat6GOBP_Response_To_HormoneMouseEmbryorep_33.6e-133
Stat6GOBP_Response_To_Nitrogen_CompoundMouseEmbryorep_3 0.0e+00
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
Stat6GOBP_Response_To_Peptide_HormoneMouseEmbryorep_3 0.0e+00
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseEmbryorep_32.7e-115
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseEmbryorep_6 1.5e-08
Stat6GOBP_Response_To_Endogenous_StimulusMouseEmbryorep_6 2.0e-17
Stat6GOBP_Cytokine_ProductionMouseKidneyNep 1.3e-32
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyNep 4.4e-12
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseKidneyNep 5.6e-37
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseKidneyNep 4.9e-40
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseKidneyNep 1.8e-38
Stat6GOBP_Response_To_Endogenous_StimulusMouseKidneyNep 6.3e-23
Stat6GOBP_Response_To_HormoneMouseKidneyNep 6.3e-23
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyNep 6.8e-28
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyNep 4.4e-12
Stat6GOBP_Adaptive_ThermogenesisMouseKidneySham 2.7e-10
Stat6GOBP_Temperature_HomeostasisMouseKidneySham 7.4e-36
Stat6GOBP_Adaptive_ThermogenesisMouseKidneyrep_2 2.9e-21
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseKidneyrep_2 4.4e-08
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseKidneyrep_2 5.2e-82
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_2 4.5e-89
Stat6GOBP_Cellular_Response_To_PeptideMouseKidneyrep_2 5.9e-31
Stat6GOBP_Cellular_Response_To_Peptide_Hormone_StimulusMouseKidneyrep_2 3.3e-30
Stat6GOBP_Defense_ResponseMouseKidneyrep_26.8e-127
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyrep_2 1.5e-13
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseKidneyrep_2 2.4e-27
Stat6GOBP_Homeostatic_ProcessMouseKidneyrep_2 2.2e-10
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseKidneyrep_2 9.5e-21
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseKidneyrep_2 1.3e-51
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseKidneyrep_2 3.1e-07
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseKidneyrep_22.1e-103
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseKidneyrep_2 2.7e-43
Stat6GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseKidneyrep_2 4.5e-10
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseKidneyrep_2 8.3e-40
Stat6GOBP_Response_To_CytokineMouseKidneyrep_2 3.1e-14
Stat6GOBP_Response_To_Endogenous_StimulusMouseKidneyrep_2 1.1e-44
Stat6GOBP_Response_To_Growth_HormoneMouseKidneyrep_27.6e-191
Stat6GOBP_Response_To_HormoneMouseKidneyrep_2 3.2e-12
Stat6GOBP_Response_To_Interleukin_4MouseKidneyrep_2 4.2e-09
Stat6GOBP_Response_To_Nitrogen_CompoundMouseKidneyrep_2 1.0e-56
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_26.6e-112
Stat6GOBP_Response_To_PeptideMouseKidneyrep_2 1.4e-66
Stat6GOBP_Response_To_Peptide_HormoneMouseKidneyrep_2 6.2e-41
Stat6GOBP_Temperature_HomeostasisMouseKidneyrep_2 4.5e-41
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyrep_2 2.5e-32
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseLiverCN16-D2 2.3e-09
Stat6GOBP_Response_To_Growth_HormoneMouseLiverCN16-D2 2.4e-07
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseLiverCN16-E1 5.7e-10
Stat6GOBP_Type_I_Interferon_ProductionMouseLiverCN65-C1 5.0e-08
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseLiverCN73-C1 5.5e-08
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseLiverrep_15 1.2e-07
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseLiverrep_15 6.5e-46
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseLiverrep_15 7.9e-07
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseLiverrep_16 1.0e-14
Stat6GOBP_Cellular_Response_To_PeptideMouseLiverrep_16 4.3e-08
Stat6GOBP_Defense_ResponseMouseLiverrep_16 8.0e-16
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseLiverrep_16 4.4e-20
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseLiverrep_16 1.9e-17
Stat6GOBP_Receptor_Signaling_Pathway_Via_StatMouseLiverrep_16 4.6e-32
Stat6GOBP_Response_To_CytokineMouseLiverrep_16 1.4e-13
Stat6GOBP_Response_To_Interleukin_4MouseLiverrep_16 1.3e-10
Stat6GOBP_Response_To_PeptideMouseLiverrep_16 1.2e-11
Stat6GOBP_Response_To_Peptide_HormoneMouseLiverrep_16 4.8e-07
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLiverrep_16 1.8e-10
Stat6GOBP_Type_I_Interferon_ProductionMouseLiverrep_16 2.9e-18
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseBrainrep_1 4.8e-14
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseBrainrep_1 3.8e-16
Stat6GOBP_Response_To_Growth_HormoneMouseIntestinerep_2 1.3e-56
Stat6GOBP_Adaptive_ThermogenesisMouseLymphMS-1 1.1e-14
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseLymphMS-1 6.7e-10
Stat6GOBP_Cellular_Response_To_Hormone_StimulusMouseLymphMS-1 9.2e-13
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseLymphMS-1 7.5e-11
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 7.5e-11
Stat6GOBP_Cellular_Response_To_PeptideMouseLymphMS-1 3.2e-14
Stat6GOBP_Cellular_Response_To_Peptide_Hormone_StimulusMouseLymphMS-1 1.6e-09
Stat6GOBP_Cytokine_Mediated_Signaling_PathwayMouseLymphMS-1 6.7e-17
Stat6GOBP_Cytokine_ProductionMouseLymphMS-1 1.1e-16
Stat6GOBP_Defense_ResponseMouseLymphMS-1 8.6e-18
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseLymphMS-1 1.6e-14
Stat6GOBP_Homeostatic_ProcessMouseLymphMS-1 2.3e-12
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseLymphMS-1 1.1e-12
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseLymphMS-1 4.7e-12
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseLymphMS-1 7.0e-13
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseLymphMS-1 7.3e-12
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseLymphMS-1 1.4e-15
Stat6GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseLymphMS-1 4.4e-12
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseLymphMS-1 1.7e-12
Stat6GOBP_Receptor_Signaling_Pathway_Via_StatMouseLymphMS-1 3.9e-13
Stat6GOBP_Response_To_CytokineMouseLymphMS-1 5.7e-15
Stat6GOBP_Response_To_Endogenous_StimulusMouseLymphMS-1 3.9e-13
Stat6GOBP_Response_To_HormoneMouseLymphMS-1 7.3e-10
Stat6GOBP_Response_To_Nitrogen_CompoundMouseLymphMS-1 1.8e-09
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 1.8e-09
Stat6GOBP_Response_To_PeptideMouseLymphMS-1 3.9e-14
Stat6GOBP_Response_To_Peptide_HormoneMouseLymphMS-1 5.0e-11
Stat6GOBP_Temperature_HomeostasisMouseLymphMS-1 9.0e-11
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLymphMS-1 8.3e-14
Stat6GOBP_Type_I_Interferon_ProductionMouseLymphMS-1 2.0e-08
Stat6GOBP_Cytokine_ProductionMouseLungrep_1 1.7e-08
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseLungrep_1 2.1e-08
Stat6GOBP_Response_To_CytokineMouseLungrep_1 1.2e-17
Stat6GOBP_Response_To_Endogenous_StimulusMouseLungrep_1 2.0e-30
Stat6GOBP_Response_To_HormoneMouseLungrep_1 1.1e-09
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseLungrep_1 1.2e-19
Stat6GOBP_Type_I_Interferon_ProductionMouseBrainrep_4 6.8e-13
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseBrainrep_6 5.4e-37
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseBrainrep_7 3.3e-16
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseBrainrep_7 2.6e-23
Stat6GOBP_Response_To_Growth_HormoneMouseBrainHP_ad_rep2 6.6e-09
Stat6GOBP_Interleukin_4_Mediated_Signaling_PathwayMouseBrainHP_ad_rep3 8.7e-11
Stat6GOBP_Cellular_Response_To_Growth_Hormone_StimulusMouseBrainHP_ad_rep7 2.1e-18
Stat6GOBP_Cellular_Response_To_Hormone_StimulusMouseBrainHP_ad_rep7 9.8e-13
Stat6GOBP_Cellular_Response_To_Nitrogen_CompoundMouseBrainHP_ad_rep7 2.8e-12
Stat6GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 2.6e-10
Stat6GOBP_Cellular_Response_To_PeptideMouseBrainHP_ad_rep7 1.1e-10
Stat6GOBP_Cellular_Response_To_Peptide_Hormone_StimulusMouseBrainHP_ad_rep7 2.1e-08
Stat6GOBP_Defense_ResponseMouseBrainHP_ad_rep7 5.6e-10
Stat6GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainHP_ad_rep7 2.5e-10
Stat6GOBP_Positive_Regulation_Of_Gene_ExpressionMouseBrainHP_ad_rep7 4.4e-07
Stat6GOBP_Positive_Regulation_Of_Multicellular_Organismal_ProcessMouseBrainHP_ad_rep7 9.1e-08
Stat6GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_ProcessMouseBrainHP_ad_rep7 2.8e-11
Stat6GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_IiMouseBrainHP_ad_rep7 7.3e-11
Stat6GOBP_Receptor_Signaling_Pathway_Via_StatMouseBrainHP_ad_rep7 3.7e-10
Stat6GOBP_Response_To_CytokineMouseBrainHP_ad_rep7 2.1e-08
Stat6GOBP_Response_To_Endogenous_StimulusMouseBrainHP_ad_rep7 6.3e-10
Stat6GOBP_Response_To_HormoneMouseBrainHP_ad_rep7 4.0e-10
Stat6GOBP_Response_To_Interleukin_4MouseBrainHP_ad_rep7 6.3e-09
Stat6GOBP_Response_To_Nitrogen_CompoundMouseBrainHP_ad_rep7 3.5e-10
Stat6GOBP_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 4.2e-09
Stat6GOBP_Response_To_PeptideMouseBrainHP_ad_rep7 5.1e-11
Stat6GOBP_Response_To_Peptide_HormoneMouseBrainHP_ad_rep7 2.9e-11
Stat6GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainHP_ad_rep7 9.5e-09
Stat6GOBP_Type_I_Interferon_ProductionMouseBrainHP_ad_rep7 1.1e-07
Stat6GOBP_Growth_Hormone_Receptor_Signaling_Pathway_Via_Jak_StatMouseBrainHP_ad_rep8 7.0e-07
Stat6GOBP_Adaptive_ThermogenesisMouseBrainHP_adpolb_rep1 4.2e-07
Stat6GOBP_Cytokine_Mediated_Signaling_PathwayMouseBrainHP_polb_rep9 5.5e-07
Stat6GOBP_Cytokine_ProductionMouseBrainHP_polb_rep9 1.6e-09
Stat6GOBP_Homeostatic_ProcessMouseBrainHP_polb_rep9 6.4e-11
Stat6GOBP_Multicellular_Organismal_HomeostasisMouseBrainHP_polb_rep9 3.2e-07
Stat6GOBP_Positive_Regulation_Of_Cold_Induced_ThermogenesisMouseBrainHP_polb_rep9 3.4e-10
Stat6GOBP_Positive_Regulation_Of_Cytokine_ProductionMouseBrainHP_polb_rep9 1.9e-09
Stat6GOBP_Positive_Regulation_Of_Type_I_Interferon_ProductionMouseBrainHP_polb_rep9 1.2e-09
Stat6GOBP_Temperature_HomeostasisMouseBrainHP_polb_rep9 3.7e-12

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Stat6 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Stat6 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Stat6 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score
STAT6UterusearlyGlandularZNF345,SLC44A4,MAMLD1, etc.0.346
STAT6UterusearlyGlandular_secretoryZNF345,SLC44A4,MAMLD1, etc.0.285
STAT6UterusearlySOX9_LGR5ZNF345,SLC44A4,MAMLD1, etc.0.352
STAT6UterusearlySOX9ZNF345,SLC44A4,MAMLD1, etc.0.388
STAT6UterusmidGlandular_secretoryKCNMB3,CHST9,PRAME, etc.0.266
STAT6UteruslateGlandular_secretoryPDE4D,VAV1,HOXB-AS1, etc.0.343

check button Motif information.

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Related Drugs for Stat6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Stat6

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Stat6C0018922hemangiopericytoma2ORPHANET
Stat6C1266119Solitary fibrous tumor2CTD_human;ORPHANET
Stat6C0011615Dermatitis, Atopic1CTD_human
Stat6C0013604Edema1CTD_human
Stat6C0018671Head and Neck Neoplasms1CTD_human
Stat6C0018675Head Neoplasms1CTD_human
Stat6C0027533Neck Neoplasms1CTD_human
Stat6C0034069Pulmonary Fibrosis1CTD_human
Stat6C0086196Eczema, Infantile1CTD_human
Stat6C0151603Anasarca1CTD_human
Stat6C0278996Malignant Head and Neck Neoplasm1CTD_human
Stat6C0746787Cancer of Neck1CTD_human
Stat6C0751177Cancer of Head1CTD_human
Stat6C0887900Upper Aerodigestive Tract Neoplasms1CTD_human
Stat6C4721507Alveolitis, Fibrosing1CTD_human