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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Srp14 (spascer ID:20813)

Gene summary for Srp14

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Srp14
	Gene ID	20813
	Gene name	signal recognition particle 14
	Synonyms	14kDa\|AW536328
	Cytomap	2\|2 E5
	Type of gene	protein-coding
	Description	signal recognition particle 14 kDa protein(homologous Alu RNA binding protein)homologous Alu RNA-binding protein
	Modification date	20220424
	UniProtAcc	P16254

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Srp14	GO:0005786	signal recognition particle, endoplasmic reticulum targeting	21873635	Component
Srp14	GO:0045047	protein targeting to ER	21873635	Process

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Spatial pattern events for Srp14

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Srp14	Mouse	Brain	S1	34413515	1.94e-07
Srp14	Mouse	Brain	S2	34413515	1.56e-15
Srp14	Mouse	Brain	S3	34413515	1.64e-15
Srp14	Mouse	Brain	S4	34413515	1.37e-15
Srp14	Mouse	Brain	S6	34413515	1.46e-15
Srp14	Mouse	Brain	S7	34413515	1.55e-15
Srp14	Mouse	Brain	rep_1	35141374	2.02e-15
Srp14	Mouse	Brain	rep_2	35141374	5.75e-15
Srp14	Mouse	Brain	rep_3	35141374	1.64e-15
Srp14	Mouse	Brain	rep_4	35141374	1.57e-15
Srp14	Mouse	Brain	rep_5	35141374	1.47e-15
Srp14	Mouse	Brain	rep_6	35141374	1.73e-15
Srp14	Mouse	Kidney	CLP	34003797	2.19e-15
Srp14	Mouse	Kidney	IRI	34003797	3.92e-15
Srp14	Mouse	Kidney	Sham	34003797	2.58e-15
Srp14	Mouse	Kidney	rep_1	34853151	2.42e-15
Srp14	Mouse	Kidney	rep_3	34853151	4.93e-15
Srp14	Mouse	Kidney	rep_5	34853151	5.45e-15
Srp14	Mouse	Brain	rep_1	33469025	1.30e-15
Srp14	Mouse	Brain	rep_1	35027729	1.66e-15
Srp14	Mouse	Brain	rep_2	35027729	1.57e-15
Srp14	Mouse	Brain	rep_3	35027729	1.32e-15
Srp14	Mouse	Brain	rep_4	35027729	1.76e-15
Srp14	Mouse	Brain	rep_5	35027729	1.46e-15
Srp14	Mouse	Intestine	rep_3	35149721	7.40e-10
Srp14	Mouse	Intestine	rep_4	35149721	4.57e-14
Srp14	Mouse	Brain	B02_D1	32702314	7.48e-08
Srp14	Mouse	Testicle	rep_5	34731600	7.03e-07
Srp14	Mouse	Brain	rep_1	35210624	3.92e-11
Srp14	Mouse	Brain	rep_2	35210624	1.78e-12
Srp14	Mouse	Brain	rep_3	35210624	1.14e-11
Srp14	Mouse	Brain	rep_4	35210624	6.49e-06
Srp14	Mouse	Brain	rep_6	35210624	1.60e-10
Srp14	Mouse	Brain	rep_7	35210624	4.81e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E

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Spatial pattern pathway has Srp14 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Srp14	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Spinal cord	L7CN45_C1	9.9e-07
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Srp14	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Srp14	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Srp14	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	6.7e-06
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Srp14	GOBP_Protein_Localization_To_Organelle	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Srp14	GOBP_Protein_Targeting	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Spinal cord	L7CN45_C1	2.9e-06
Srp14	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Spinal cord	L7CN47_C1	7.0e-06
Srp14	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Spinal cord	L7CN47_D1	5.5e-06
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_27	3.0e-05
Srp14	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Srp14	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Srp14	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_1	2.6e-13
Srp14	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Brain	rep_1	2.9e-25
Srp14	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Srp14	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_1	2.1e-07
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_1	1.3e-13
Srp14	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Brain	rep_3	1.5e-99
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Brain	rep_3	7.8e-194
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Brain	rep_3	1.2e-180
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Brain	rep_3	2.7e-132
Srp14	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Brain	rep_3	3.1e-200
Srp14	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	rep_3	6.3e-172
Srp14	GOBP_Protein_Targeting	Mouse	Brain	rep_3	2.9e-187
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Brain	rep_3	1.5e-197
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.3e-32
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_6	1.4e-16
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Embryo	rep_14	6.3e-46
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Embryo	rep_14	4.5e-41
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Embryo	rep_14	1.7e-10
Srp14	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	3.8e-12
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Embryo	rep_14	2.9e-28
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	1.7e-32
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Embryo	rep_14	4.8e-33
Srp14	GOBP_Protein_Targeting	Mouse	Embryo	rep_14	6.3e-09
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Embryo	rep_14	1.4e-25
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Embryo	rep_1	8.6e-17
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_2	3.4e-34
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Srp14	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Embryo	rep_4	1.1e-39
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	Nep	4.2e-26
Srp14	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Kidney	rep_2	4.3e-101
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Kidney	rep_2	8.2e-102
Srp14	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Kidney	rep_2	5.7e-63
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Kidney	rep_2	4.7e-11
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Kidney	rep_2	3.3e-19
Srp14	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Srp14	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Kidney	rep_2	7.5e-54
Srp14	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	2.7e-133
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Kidney	rep_2	2.2e-110
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	6.6e-105
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Kidney	rep_2	4.2e-59
Srp14	GOBP_Protein_Localization_To_Organelle	Mouse	Kidney	rep_2	3.4e-44
Srp14	GOBP_Protein_Targeting	Mouse	Kidney	rep_2	1.7e-40
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Kidney	rep_2	2.4e-30
Srp14	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Liver	CN16-D1	2.3e-09
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Liver	CN16-D2	2.2e-09
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Liver	CN16-D2	6.1e-07
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Liver	CN16-E1	5.1e-12
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Liver	rep_15	2.4e-09
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Liver	rep_16	1.6e-18
Srp14	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Liver	rep_16	2.2e-20
Srp14	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Lymph	MS-1	9.7e-16
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Lymph	MS-1	2.5e-14
Srp14	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Lymph	MS-1	1.0e-08
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Lymph	MS-1	1.3e-10
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Lymph	MS-1	3.3e-11
Srp14	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Srp14	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Lymph	MS-1	3.0e-17
Srp14	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	5.6e-21
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Lymph	MS-1	1.0e-18
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	6.6e-07
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Lymph	MS-1	3.6e-07
Srp14	GOBP_Protein_Localization_To_Organelle	Mouse	Lymph	MS-1	1.4e-09
Srp14	GOBP_Protein_Targeting	Mouse	Lymph	MS-1	2.1e-09
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Lymph	MS-1	3.9e-09
Srp14	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_4	2.9e-33
Srp14	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Srp14	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	6.4e-19
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_4	3.5e-20
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.7e-62
Srp14	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Srp14	GOBP_Cotranslational_Protein_Targeting_To_Membrane	Mouse	Brain	HP_ad_rep7	2.6e-09
Srp14	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Brain	HP_ad_rep7	6.0e-10
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Mouse	Brain	HP_ad_rep7	6.1e-09
Srp14	GOBP_Intracellular_Protein_Transport	Mouse	Brain	HP_ad_rep7	3.6e-08
Srp14	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Srp14	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_ad_rep7	4.4e-14
Srp14	GOBP_Protein_Localization_To_Endoplasmic_Reticulum	Mouse	Brain	HP_ad_rep7	7.2e-10
Srp14	GOBP_Protein_Localization_To_Organelle	Mouse	Brain	HP_ad_rep7	4.8e-12
Srp14	GOBP_Protein_Targeting_To_Membrane	Mouse	Brain	HP_ad_rep7	1.1e-09
Srp14	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Srp14	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Srp14	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	HP_polb_rep9	8.8e-09
Srp14	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Mouse	Brain	HP_polb_rep9	3.1e-10
Srp14	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Srp14	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Srp14	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_polb_rep9	2.8e-07
Srp14	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	HP_polb_rep9	2.6e-11
Srp14	GOBP_Protein_Targeting	Mouse	Brain	HP_polb_rep9	1.8e-11

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Srp14 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Srp14 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Srp14 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Srp14

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Srp14

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source