|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Srm (spascer ID:20810) |
Gene summary for Srm |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Srm | Gene ID | 20810 |
| Gene name | spermidine synthase |
| Synonyms | AA407669|SpdST|SpdSy |
| Cytomap | 4|4 E2 |
| Type of gene | protein-coding |
| Description | spermidine synthaseputrescine aminopropyltransferase |
| Modification date | 20220424 |
| UniProtAcc | Q64674 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Srm | GO:0004766 | spermidine synthase activity | 21873635 | Function |
| Srm | GO:0006596 | polyamine biosynthetic process | 21873635 | Process |
| Srm | GO:0008295 | spermidine biosynthetic process | 21873635 | Process |
Top |
Spatial pattern events for Srm |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Srm | Mouse | Brain | S4 | 34413515 | 8.32e-12 |
| Srm | Mouse | Brain | rep_1 | 35141374 | 4.57e-13 |
| Srm | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Srm | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Srm | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Srm | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Srm | Mouse | Brain | rep_6 | 35141374 | 3.15e-15 |
| Srm | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Srm | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Srm | Mouse | Embryo | rep_15 | 33188776 | 2.07e-13 |
| Srm | Mouse | Kidney | CLP | 34003797 | 9.64e-07 |
| Srm | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Srm | Mouse | Kidney | rep_1 | 34853151 | 2.68e-07 |
| Srm | Mouse | Kidney | rep_5 | 34853151 | 5.45e-15 |
| Srm | Mouse | Kidney | rep_1 | 33976190 | 4.75e-06 |
| Srm | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Srm | Mouse | Brain | rep_3 | 35027729 | 2.80e-11 |
| Srm | Mouse | Brain | rep_4 | 35027729 | 1.39e-09 |
| Srm | Mouse | Brain | rep_5 | 35027729 | 1.93e-11 |
| Srm | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Srm | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Srm | Mouse | Lung | rep_1 | 35290801 | 3.97e-09 |
| Srm | Mouse | Lung | rep_2 | 35290801 | 1.56e-08 |
| Srm | Mouse | Lung | rep_4 | 35290801 | 1.64e-13 |
| Srm | Mouse | Brain | rep_1 | 35210624 | 1.85e-06 |
| Srm | Mouse | Brain | rep_3 | 35210624 | 4.28e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_5_H&E  |  |
Kidney_rep_1_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_4_H&E  |  |
Top |
Spatial pattern pathway has Srm envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Srm | GOBP_Polyamine_Metabolic_Process | Mouse | Spinal cord | L7bCN02_E1 | 1.4e-06 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 5.6e-08 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Spinal cord | L7CN45_C1 | 8.0e-07 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Spinal cord | L7CN45_C1 | 3.3e-07 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 7.7e-06 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Brain | rep_37 | 7.3e-05 |
| Srm | GOBP_Amine_Biosynthetic_Process | Mouse | Brain | rep_3 | 1.3e-158 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Brain | rep_3 | 2.7e-76 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.9e-144 |
| Srm | GOBP_Polyamine_Biosynthetic_Process | Mouse | Brain | rep_3 | 1.7e-195 |
| Srm | GOBP_Polyamine_Metabolic_Process | Mouse | Brain | rep_3 | 4.1e-189 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Brain | rep_3 | 1.2e-08 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Brain | rep_3 | 9.6e-172 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Brain | rep_3 | 8.1e-62 |
| Srm | GOBP_Polyamine_Biosynthetic_Process | Mouse | Embryo | rep_6 | 4.2e-08 |
| Srm | GOBP_Amine_Biosynthetic_Process | Mouse | Embryo | rep_14 | 2.2e-31 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Embryo | rep_14 | 1.5e-31 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Embryo | rep_14 | 2.4e-12 |
| Srm | GOBP_Polyamine_Metabolic_Process | Mouse | Embryo | rep_14 | 1.0e-20 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Embryo | rep_14 | 5.8e-43 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Embryo | rep_14 | 4.3e-12 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Embryo | rep_1 | 8.2e-211 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Embryo | rep_2 | 9.5e-207 |
| Srm | GOBP_Amine_Biosynthetic_Process | Mouse | Kidney | rep_2 | 3.7e-182 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Kidney | rep_2 | 1.8e-139 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Kidney | rep_2 | 8.9e-78 |
| Srm | GOBP_Polyamine_Biosynthetic_Process | Mouse | Kidney | rep_2 | 1.2e-59 |
| Srm | GOBP_Polyamine_Metabolic_Process | Mouse | Kidney | rep_2 | 1.7e-76 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Kidney | rep_2 | 3.1e-14 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Kidney | rep_2 | 1.8e-20 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Kidney | rep_2 | 6.9e-11 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Kidney | rep_3 | 3.5e-04 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Liver | CN16-D2 | 5.7e-08 |
| Srm | GOBP_Polyamine_Biosynthetic_Process | Mouse | Liver | CN16-E1 | 1.6e-09 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Liver | rep_15 | 1.1e-09 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Liver | rep_16 | 1.4e-13 |
| Srm | GOBP_Amine_Biosynthetic_Process | Mouse | Lymph | MS-1 | 1.4e-07 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Lymph | MS-1 | 2.2e-15 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Lymph | MS-1 | 1.4e-09 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Lymph | MS-1 | 5.7e-15 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Lymph | MS-1 | 3.2e-08 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Lung | rep_1 | 1.2e-17 |
| Srm | GOBP_Spermidine_Metabolic_Process | Mouse | Brain | HP_ad_rep3 | 1.4e-12 |
| Srm | GOBP_Amine_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.0e-08 |
| Srm | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-08 |
| Srm | GOBP_Polyamine_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 5.2e-11 |
| Srm | GOBP_Polyamine_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 8.6e-10 |
| Srm | GOBP_Response_To_Cytokine | Mouse | Brain | HP_ad_rep7 | 2.1e-08 |
| Srm | GOBP_Response_To_Leukemia_Inhibitory_Factor | Mouse | Brain | HP_ad_rep7 | 2.3e-07 |
| Srm | GOBP_Amine_Biosynthetic_Process | Mouse | Brain | HP_polb_rep9 | 6.1e-14 |
Top |
Srm function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Srm function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Srm envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Srm |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Srm |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Srm | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
