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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Sephs2 (spascer ID:20768)

Gene summary for Sephs2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Sephs2
	Gene ID	20768
	Gene name	selenophosphate synthetase 2
	Synonyms	Sps2\|Ysg3
	Cytomap	7 F3\|7 69.43 cM
	Type of gene	protein-coding
	Description	selenide, water dikinase 2selenium donor protein 2selenophosphate synthase 2the SelD gene product
	Modification date	20220424
	UniProtAcc	P97364

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Sephs2	GO:0004756	selenide, water dikinase activity	21873635	Function
Sephs2	GO:0005737	cytoplasm	21873635	Component
Sephs2	GO:0016260	selenocysteine biosynthetic process	21873635	Process

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Spatial pattern events for Sephs2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Sephs2	Mouse	Embryo	rep_13	33188776	2.67e-08
Sephs2	Mouse	Kidney	CLP	34003797	2.19e-15
Sephs2	Mouse	Kidney	IRI	34003797	2.29e-15
Sephs2	Mouse	Kidney	Sham	34003797	2.58e-15
Sephs2	Mouse	Kidney	rep_1	34853151	2.42e-15
Sephs2	Mouse	Kidney	rep_2	34853151	4.68e-07
Sephs2	Mouse	Kidney	rep_3	34853151	2.94e-15
Sephs2	Mouse	Kidney	rep_4	34853151	1.17e-11
Sephs2	Mouse	Kidney	rep_5	34853151	3.18e-15
Sephs2	Mouse	Liver	rep_14	35021063	2.14e-10
Sephs2	Mouse	Liver	rep_17	35021063	4.67e-13
Sephs2	Mouse	Liver	rep_19	35021063	1.93e-09
Sephs2	Mouse	Liver	rep_20	35021063	6.48e-13
Sephs2	Mouse	Liver	rep_23	35021063	4.95e-07
Sephs2	Mouse	Brain	rep_5	35027729	1.39e-06
Sephs2	Mouse	Intestine	rep_3	35149721	1.85e-06
Sephs2	Mouse	Lung	rep_4	35290801	2.81e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Liver_rep_14_H&E
Liver_rep_17_H&E
Liver_rep_19_H&E
Liver_rep_20_H&E
Liver_rep_23_H&E
Brain_rep_5_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Sephs2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.5e-07
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.8e-07
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Sephs2	GOBP_Serine_Family_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_D1	6.8e-07
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_71	7.6e-05
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	2.8e-178
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	8.5e-191
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	2.0e-17
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-38
Sephs2	GOBP_Serine_Family_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	4.9e-166
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Embryo	rep_6	4.1e-12
Sephs2	GOBP_Serine_Family_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_6	2.0e-19
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-20
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_14	7.1e-24
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_4	1.5e-14
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-36
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-34
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	7.1e-54
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Liver	rep_15	4.5e-13
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-13
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-13
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-15
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	8.1e-12
Sephs2	GOBP_Serine_Family_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-10
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_4	1.9e-21
Sephs2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.5e-12
Sephs2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.0e-14
Sephs2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Sephs2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Sephs2	GOBP_Serine_Family_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	6.3e-08
Sephs2	GOBP_Serine_Family_Amino_Acid_Biosynthetic_Process	Mouse	Brain	HP_adpolb_rep1	3.5e-07
Sephs2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	3.8e-07
Sephs2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Sephs2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Sephs2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Sephs2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Sephs2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Sephs2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Sephs2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source