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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ighmbp2 (spascer ID:20589)

Gene summary for Ighmbp2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ighmbp2
	Gene ID	20589
	Gene name	immunoglobulin mu binding protein 2
	Synonyms	AEP\|Catf1\|RIPE3b1\|Smbp-2\|Smbp2\|Smubp2\|nmd\|sma
	Cytomap	19 A\|19 3.03 cM
	Type of gene	protein-coding
	Description	DNA-binding protein SMUBP-2ATP-dependent helicase IGHMBP2antifreeze enhancer-binding proteincardiac transcription factor 1immunoglobulin S mu binding protein 2neuromuscular degenerationp110 subunit
	Modification date	20220424
	UniProtAcc	P40694

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ighmbp2	GO:0005634	nucleus	21873635	Component
Ighmbp2	GO:0005737	cytoplasm	21873635	Component
Ighmbp2	GO:0043139	5'-3' DNA helicase activity	21873635	Function

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Spatial pattern events for Ighmbp2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ighmbp2	Mouse	Kidney	CLP	34003797	3.15e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E

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Spatial pattern pathway has Ighmbp2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Spinal cord	L7CN45_C1	8.1e-07
Ighmbp2	GOBP_Dna_Recombination	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Ighmbp2	GOBP_Dna_Repair	Mouse	Spinal cord	L7CN45_C1	9.4e-06
Ighmbp2	GOBP_Dna_Replication	Mouse	Spinal cord	L7CN45_C1	2.8e-07
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Spinal cord	L7CN47_C1	2.6e-06
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Brain	rep_11	3.6e-05
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Brain	rep_11	2.1e-05
Ighmbp2	GOBP_Dna_Replication	Mouse	Brain	rep_27	6.4e-06
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Ighmbp2	GOBP_Dna_Recombination	Mouse	Brain	rep_1	6.8e-13
Ighmbp2	GOBP_Dna_Replication	Mouse	Brain	rep_1	4.3e-10
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	rep_3	2.5e-86
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Brain	rep_3	7.4e-54
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Brain	rep_3	4.9e-189
Ighmbp2	GOBP_Dna_Repair	Mouse	Brain	rep_3	4.0e-216
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	rep_3	2.1e-69
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Embryo	rep_14	3.7e-18
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Embryo	rep_14	2.1e-08
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Embryo	rep_14	5.1e-11
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Embryo	rep_14	2.8e-15
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Ighmbp2	GOBP_Dna_Recombination	Mouse	Embryo	rep_2	0.0e+00
Ighmbp2	GOBP_Dna_Repair	Mouse	Embryo	rep_2	1.6e-282
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Embryo	rep_3	1.5e-48
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Kidney	rep_2	1.4e-38
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Kidney	rep_2	2.0e-24
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Ighmbp2	GOBP_Dna_Recombination	Mouse	Kidney	rep_2	2.7e-14
Ighmbp2	GOBP_Dna_Repair	Mouse	Kidney	rep_2	5.5e-70
Ighmbp2	GOBP_Dna_Replication	Mouse	Kidney	rep_2	5.9e-43
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Kidney	rep_2	2.9e-85
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-09
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Lymph	MS-1	7.1e-07
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Ighmbp2	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	8.0e-10
Ighmbp2	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Ighmbp2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Ighmbp2	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Ighmbp2	GOBP_Dna_Conformation_Change	Mouse	Brain	HP_ad_rep7	1.3e-13
Ighmbp2	GOBP_Dna_Geometric_Change	Mouse	Brain	HP_ad_rep7	1.0e-10
Ighmbp2	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Ighmbp2	GOBP_Dna_Recombination	Mouse	Brain	HP_ad_rep7	1.4e-08
Ighmbp2	GOBP_Dna_Repair	Mouse	Brain	HP_ad_rep7	2.4e-12
Ighmbp2	GOBP_Dna_Replication	Mouse	Brain	HP_ad_rep7	1.1e-10
Ighmbp2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Ighmbp2	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	4.4e-10
Ighmbp2	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10

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Ighmbp2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ighmbp2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ighmbp2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ighmbp2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ighmbp2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Ighmbp2	C1858517	SPINAL MUSCULAR ATROPHY WITH RESPIRATORY DISTRESS 1	8	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Ighmbp2	C4015349	CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2S	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT