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Spatial pattern gene: Nhs (spascer ID:195727) |
Gene summary for Nhs |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Nhs | Gene ID | 195727 |
| Gene name | NHS actin remodeling regulator |
| Synonyms | Gm389|Gm48|Nhs1|Xcat |
| Cytomap | X F4|X 74.17 cM |
| Type of gene | protein-coding |
| Description | Nance-Horan syndrome proteinNance-Horan syndrome |
| Modification date | 20220424 |
| UniProtAcc |
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| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Nhs | GO:0002088 | lens development in camera-type eye | 21873635 | Process |
| Nhs | GO:0030154 | cell differentiation | 21873635 | Process |
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Spatial pattern events for Nhs |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Nhs | Mouse | Embryo | 4E | 34210887 | 1.16e-07 |
| Nhs | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Nhs | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |
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Spatial pattern pathway has Nhs envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Spinal cord | CN94_E1 | 4.5e-06 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Spinal cord | L7CN45_C1 | 1.0e-08 |
| Nhs | GOBP_Lens_Development_In_Camera_Type_Eye | Mouse | Spinal cord | L7CN45_C1 | 7.8e-08 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Spinal cord | L7CN45_C1 | 3.4e-08 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Brain | rep_27 | 4.9e-05 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Brain | rep_27 | 1.2e-05 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Brain | rep_72 | 4.7e-05 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Brain | rep_1 | 2.1e-13 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Brain | rep_1 | 1.6e-12 |
| Nhs | GOBP_Lens_Development_In_Camera_Type_Eye | Mouse | Brain | rep_3 | 5.0e-09 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Brain | rep_3 | 1.6e-123 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Embryo | rep_1 | 2.6e-46 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Embryo | rep_1 | 1.3e-72 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Embryo | rep_3 | 2.1e-266 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Kidney | rep_2 | 4.7e-27 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Kidney | rep_2 | 7.2e-08 |
| Nhs | GOBP_Lens_Development_In_Camera_Type_Eye | Mouse | Liver | rep_16 | 1.9e-16 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Lymph | MS-1 | 3.1e-10 |
| Nhs | GOBP_Lens_Development_In_Camera_Type_Eye | Mouse | Lymph | MS-1 | 1.2e-09 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Lymph | MS-1 | 1.5e-10 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Lymph | MS-1 | 1.2e-07 |
| Nhs | GOBP_Camera_Type_Eye_Development | Mouse | Brain | HP_ad_rep7 | 3.5e-12 |
| Nhs | GOBP_Lens_Development_In_Camera_Type_Eye | Mouse | Brain | HP_ad_rep7 | 3.2e-08 |
| Nhs | GOBP_Sensory_Organ_Development | Mouse | Brain | HP_ad_rep7 | 4.6e-10 |
| Nhs | GOBP_Sensory_System_Development | Mouse | Brain | HP_ad_rep7 | 1.6e-11 |
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Nhs function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Nhs function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Nhs envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Nhs |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Nhs |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Nhs | C0796085 | Nance-Horan syndrome | 6 | CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Nhs | C0392557 | Nuclear cataract | 3 | ORPHANET |
| Nhs | C1112705 | Nuclear non-senile cataract | 3 | ORPHANET |
| Nhs | C4049004 | CATARACT 40 | 2 | GENOMICS_ENGLAND |
