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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Reps2 (spascer ID:194590)

Gene summary for Reps2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Reps2

Gene ID

194590

Gene nameRALBP1 associated Eps domain containing protein 2
SynonymsPOB1
CytomapX|X F4
Type of geneprotein-coding
DescriptionralBP1-associated Eps domain-containing protein 2partner of RalBP1ralBP1-interacting protein 2
Modification date20220428
UniProtAcc

Q80XA6


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Reps2

GO:0005737

cytoplasm

21873635

Component
Reps2

GO:0005886

plasma membrane

21873635

Component
Reps2

GO:0006897

endocytosis

21873635

Process
Reps2

GO:0016197

endosomal transport

21873635

Process

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Spatial pattern events for Reps2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Reps2MouseBrainS1 344135152.07e-15
Reps2MouseBrainS2 344135151.56e-15
Reps2MouseBrainS3 344135151.64e-15
Reps2MouseBrainS4 344135151.37e-15
Reps2MouseBrainS6 344135151.46e-15
Reps2MouseBrainS7 344135151.55e-15
Reps2MouseBrain01B 326376225.61e-09
Reps2MouseBrain09A 326376222.85e-06
Reps2MouseBrain11A 326376226.94e-08
Reps2MouseBrain12B 326376221.77e-12
Reps2MouseBrain14A 326376221.61e-06
Reps2MouseBrain14B 326376229.10e-12
Reps2MouseBrain16A 326376228.18e-07
Reps2MouseBrain16B 326376222.04e-09
Reps2MouseBrain17A 326376221.19e-14
Reps2MouseBrain17B 326376224.11e-14
Reps2MouseBrain18A 326376221.46e-13
Reps2MouseBrain18B 326376229.13e-13
Reps2MouseBrain19A 326376224.39e-12
Reps2MouseBrain19B 326376221.19e-11
Reps2MouseBrain20A 326376221.49e-14
Reps2MouseBrain20B 326376225.33e-07
Reps2MouseBrain21A 326376224.17e-14
Reps2MouseBrain21B 326376224.11e-14
Reps2MouseBrain22A 326376221.50e-14
Reps2MouseBrain22B 326376221.50e-14
Reps2MouseBrain23A 326376221.92e-13
Reps2MouseBrain23B 326376221.86e-14
Reps2MouseBrain24A 326376222.45e-14
Reps2MouseBrain24B 326376228.63e-12
Reps2MouseBrain27A 326376224.88e-06
Reps2MouseBrain27B 326376228.95e-06
Reps2MouseBrain29A 326376221.92e-13
Reps2MouseBrain29B 326376228.86e-12
Reps2MouseBrain30A 326376222.93e-11
Reps2MouseBrain31A 326376221.43e-13
Reps2MouseBrain33A 326376221.50e-14
Reps2MouseBrain33B 326376227.62e-12
Reps2MouseBrain34A 326376224.12e-10
Reps2MouseBrain35A 326376221.48e-14
Reps2MouseBrain35B 326376221.49e-10
Reps2MouseBrain37A 326376221.66e-10
Reps2MouseBrain37B 326376222.25e-10
Reps2MouseBrain38A 326376221.40e-11
Reps2MouseBrain38B 326376226.24e-12
Reps2MouseBrain39B 326376226.84e-06
Reps2MouseBrainrep_1 351413742.02e-15
Reps2MouseBrainrep_2 351413741.69e-15
Reps2MouseBrainrep_3 351413741.64e-15
Reps2MouseBrainrep_4 351413741.57e-15
Reps2MouseBrainrep_5 351413741.47e-15
Reps2MouseBrainrep_6 351413741.73e-15
Reps2MouseKidneyIRI 340037973.18e-07
Reps2MouseBrainrep_1 334690251.30e-15
Reps2MouseBrainrep_1 350277291.66e-15
Reps2MouseBrainrep_2 350277291.57e-15
Reps2MouseBrainrep_3 350277291.32e-15
Reps2MouseBrainrep_4 350277291.76e-15
Reps2MouseBrainrep_5 350277291.46e-15
Reps2MouseBrainB02_E1 327023144.15e-14
Reps2MouseBrainN02_D1 327023146.47e-08
Reps2MouseBrainN03_D2 327023143.82e-10
Reps2MouseBrainN04_D1 327023147.04e-07
Reps2MouseBrainN05_D2 327023144.82e-07
Reps2MouseLungrep_1 352908016.56e-15
Reps2MouseBrainrep_1 352106241.74e-15
Reps2MouseBrainrep_2 352106241.74e-15
Reps2MouseBrainrep_3 352106241.82e-15
Reps2MouseBrainrep_5 352106244.79e-06
Reps2MouseBrainrep_6 352106244.59e-06
Reps2MouseBrainrep_7 352106245.13e-08
Reps2MouseBrainOFB_wt_rep2 330837251.09e-03

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_IRI_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_E1_H&E
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Brain_N02_D1_H&E
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Brain_N03_D2_H&E
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Brain_N04_D1_H&E
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Brain_N05_D2_H&E
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Lung_rep_1_H&E
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Brain_OFB_wt_rep2_H&E
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Spatial pattern pathway has Reps2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Reps2GOBP_EndocytosisMouseSpinal cordCN94_E1 8.2e-06
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseSpinal cordCN94_E1 4.4e-07
Reps2GOBP_Endosomal_TransportMouseSpinal cordL7CN45_C1 4.4e-08
Reps2GOBP_Erbb_Signaling_PathwayMouseSpinal cordL7CN45_C1 5.1e-08
Reps2GOBP_Intracellular_TransportMouseSpinal cordL7CN45_C1 4.4e-06
Reps2GOBP_Membrane_OrganizationMouseSpinal cordL7CN45_C1 2.7e-07
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseSpinal cordL7CN45_C1 5.7e-08
Reps2GOBP_Endosomal_TransportMouseBrainrep_1 8.9e-24
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainrep_1 9.9e-07
Reps2GOBP_Erbb_Signaling_PathwayMouseBrainrep_1 1.3e-38
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainrep_1 8.6e-14
Reps2GOBP_EndocytosisMouseBrainrep_3 2.6e-20
Reps2GOBP_Intracellular_TransportMouseBrainrep_31.0e-102
Reps2GOBP_Membrane_OrganizationMouseBrainrep_3 1.9e-41
Reps2GOBP_Erbb_Signaling_PathwayMouseEmbryorep_14 8.5e-07
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseEmbryorep_32.7e-115
Reps2GOBP_EndocytosisMouseKidneyNep 8.3e-23
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyNep 4.4e-12
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyNep 4.4e-12
Reps2GOBP_EndocytosisMouseKidneyrep_21.4e-132
Reps2GOBP_Endosomal_TransportMouseKidneyrep_21.5e-111
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyrep_2 1.5e-13
Reps2GOBP_Erbb_Signaling_PathwayMouseKidneyrep_2 5.6e-18
Reps2GOBP_Intracellular_TransportMouseKidneyrep_2 7.9e-80
Reps2GOBP_Membrane_OrganizationMouseKidneyrep_2 8.5e-74
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyrep_2 2.5e-32
Reps2GOBP_Erbb_Signaling_PathwayMouseLiverrep_16 3.6e-32
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLiverrep_16 1.8e-10
Reps2GOBP_EndocytosisMouseLymphMS-1 1.8e-21
Reps2GOBP_Endosomal_TransportMouseLymphMS-1 9.8e-11
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseLymphMS-1 1.6e-14
Reps2GOBP_Erbb_Signaling_PathwayMouseLymphMS-1 3.4e-14
Reps2GOBP_Intracellular_TransportMouseLymphMS-1 3.3e-11
Reps2GOBP_Membrane_OrganizationMouseLymphMS-1 5.8e-20
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLymphMS-1 8.3e-14
Reps2GOBP_Endosomal_TransportMouseBrainrep_4 2.6e-13
Reps2GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainHP_ad_rep7 2.5e-10
Reps2GOBP_Erbb_Signaling_PathwayMouseBrainHP_ad_rep7 1.1e-10
Reps2GOBP_Intracellular_TransportMouseBrainHP_ad_rep7 3.1e-08
Reps2GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainHP_ad_rep7 9.5e-09
Reps2GOBP_EndocytosisMouseBrainHP_polb_rep9 3.2e-09
Reps2GOBP_Endosomal_TransportMouseBrainHP_polb_rep9 2.8e-14
Reps2GOBP_Membrane_OrganizationMouseBrainHP_polb_rep9 1.4e-13

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Reps2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Reps2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Reps2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Reps2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Reps2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Reps2C0006142Malignant neoplasm of breast1CTD_human
Reps2C0678222Breast Carcinoma1CTD_human
Reps2C1257931Mammary Neoplasms, Human1CTD_human
Reps2C1458155Mammary Neoplasms1CTD_human
Reps2C4704874Mammary Carcinoma, Human1CTD_human