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Spatial pattern gene: Ell2 (spascer ID:192657) |
Gene summary for Ell2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Ell2 | Gene ID | 192657 |
| Gene name | elongation factor for RNA polymerase II 2 |
| Synonyms | - |
| Cytomap | 13|13 C1 |
| Type of gene | protein-coding |
| Description | RNA polymerase II elongation factor ELL2ELL-related RNA polymerase II, elongation factoreleven-nineteen lysine-rich leukemia gene 2elongation factor RNA polymerase II 2 |
| Modification date | 20220424 |
| UniProtAcc | Q3UKU1 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Ell2 | GO:0000791 | euchromatin | 21873635 | Component |
| Ell2 | GO:0000987 | cis-regulatory region sequence-specific DNA binding | 21873635 | Function |
| Ell2 | GO:0008023 | transcription elongation factor complex | 21873635 | Component |
| Ell2 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter | 21873635 | Process |
| Ell2 | GO:0042795 | snRNA transcription by RNA polymerase II | 21873635 | Process |
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Spatial pattern events for Ell2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Ell2 | Mouse | Brain | S1 | 34413515 | 7.10e-15 |
| Ell2 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Ell2 | Mouse | Brain | S3 | 34413515 | 5.72e-15 |
| Ell2 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Ell2 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Ell2 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Ell2 | Mouse | Brain | 07A | 32637622 | 2.57e-08 |
| Ell2 | Mouse | Brain | 18A | 32637622 | 2.91e-06 |
| Ell2 | Mouse | Brain | 22A | 32637622 | 3.63e-09 |
| Ell2 | Mouse | Brain | 23B | 32637622 | 1.74e-07 |
| Ell2 | Mouse | Brain | 25A | 32637622 | 3.41e-10 |
| Ell2 | Mouse | Brain | 27A | 32637622 | 6.06e-07 |
| Ell2 | Mouse | Brain | 27B | 32637622 | 6.48e-07 |
| Ell2 | Mouse | Brain | 28A | 32637622 | 9.39e-10 |
| Ell2 | Mouse | Brain | 28B | 32637622 | 2.09e-07 |
| Ell2 | Mouse | Brain | 29B | 32637622 | 2.06e-11 |
| Ell2 | Mouse | Brain | 33A | 32637622 | 6.52e-06 |
| Ell2 | Mouse | Brain | rep_1 | 35141374 | 6.54e-08 |
| Ell2 | Mouse | Brain | rep_2 | 35141374 | 1.35e-11 |
| Ell2 | Mouse | Brain | rep_3 | 35141374 | 3.00e-15 |
| Ell2 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Ell2 | Mouse | Brain | rep_5 | 35141374 | 4.41e-06 |
| Ell2 | Mouse | Brain | rep_6 | 35141374 | 1.66e-08 |
| Ell2 | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Ell2 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Ell2 | Mouse | Kidney | IRI | 34003797 | 5.46e-10 |
| Ell2 | Mouse | Kidney | Sham | 34003797 | 4.30e-15 |
| Ell2 | Mouse | Kidney | rep_4 | 34853151 | 4.07e-15 |
| Ell2 | Mouse | Brain | rep_1 | 33469025 | 2.39e-09 |
| Ell2 | Mouse | Brain | rep_1 | 35027729 | 2.98e-15 |
| Ell2 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Ell2 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Ell2 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Ell2 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Ell2 | Mouse | Brain | B02_D1 | 32702314 | 7.97e-06 |
| Ell2 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Ell2 | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Ell2 | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Ell2 | Mouse | Brain | rep_6 | 35210624 | 4.04e-11 |
| Ell2 | Mouse | Brain | rep_7 | 35210624 | 1.87e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_4_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B02_D1_H&E  |  |
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Spatial pattern pathway has Ell2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Spinal cord | L7CN45_C1 | 6.4e-06 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Spinal cord | L7CN45_C1 | 9.7e-08 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Spinal cord | L7CN45_C1 | 9.0e-07 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Brain | rep_27 | 3.8e-05 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Brain | rep_27 | 4.7e-08 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Brain | rep_1 | 4.2e-15 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Brain | rep_1 | 4.3e-20 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Brain | rep_3 | 5.9e-172 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Brain | rep_3 | 1.1e-174 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Embryo | rep_6 | 2.0e-10 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Embryo | rep_14 | 1.0e-14 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Embryo | rep_14 | 2.1e-14 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Embryo | rep_14 | 2.0e-22 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Embryo | rep_1 | 0.0e+00 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Embryo | rep_1 | 0.0e+00 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Kidney | rep_2 | 5.3e-82 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Kidney | rep_2 | 4.2e-98 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Kidney | rep_2 | 4.9e-17 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Kidney | rep_2 | 3.3e-51 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Liver | CN16-D2 | 6.9e-09 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Brain | rep_1 | 5.1e-15 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Brain | rep_4 | 8.3e-08 |
| Ell2 | GOBP_Dna_Templated_Transcription_Elongation | Mouse | Brain | HP_ad_rep7 | 1.4e-14 |
| Ell2 | GOBP_Snrna_Transcription | Mouse | Brain | HP_ad_rep7 | 9.9e-16 |
| Ell2 | GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter | Mouse | Brain | HP_ad_rep7 | 9.4e-09 |
| Ell2 | GOBP_Ncrna_Transcription | Mouse | Brain | HP_adpolb_rep1 | 3.6e-07 |
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Ell2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Ell2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Ell2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Ell2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Ell2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
