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Spatial pattern gene: Abcb1b (spascer ID:18669) |
Gene summary for Abcb1b |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Abcb1b | Gene ID | 18669 |
| Gene name | ATP-binding cassette, sub-family B (MDR/TAP), member 1B |
| Synonyms | Abcb1|Mdr1|Mdr1b|Pgy-1|Pgy1|mdr |
| Cytomap | 5 A1|5 3.43 cM |
| Type of gene | protein-coding |
| Description | ATP-dependent translocase ABCB1ATP-binding cassette sub-family B member 1P glycoprotein 1multidrug resistance protein 1multidrug resistance protein 1Bphospholipid transporter ABCB1 |
| Modification date | 20220508 |
| UniProtAcc | P06795 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Abcb1b | GO:0005886 | plasma membrane | 21873635 | Component |
| Abcb1b | GO:0016021 | integral component of membrane | 21873635 | Component |
| Abcb1b | GO:0042626 | ATPase-coupled transmembrane transporter activity | 21873635 | Function |
| Abcb1b | GO:0042910 | xenobiotic transmembrane transporter activity | 21873635 | Function |
| Abcb1b | GO:0045332 | phospholipid translocation | 21873635 | Process |
| Abcb1b | GO:0090554 | phosphatidylcholine floppase activity | 21873635 | Function |
| Abcb1b | GO:0090555 | phosphatidylethanolamine flippase activity | 21873635 | Function |
| Abcb1b | GO:0099038 | ceramide floppase activity | 21873635 | Function |
| Abcb1b | GO:0099040 | ceramide translocation | 21873635 | Process |
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Spatial pattern events for Abcb1b |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Abcb1b | Mouse | Kidney | CLP | 34003797 | 6.92e-15 |
| Abcb1b | Mouse | Kidney | IRI | 34003797 | 8.46e-12 |
| Abcb1b | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Abcb1b | Mouse | Lymph | A1 | 0 | 1.45e-08 |
| Abcb1b | Mouse | Lymph | B1 | 0 | 1.22e-10 |
| Abcb1b | Mouse | Lung | rep_3 | 35290801 | 1.82e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Lung_rep_3_H&E  |  |
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Spatial pattern pathway has Abcb1b envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
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Abcb1b function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Abcb1b function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Abcb1b envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Abcb1b |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Abcb1b |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
