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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Pfkl (spascer ID:18641)

Gene summary for Pfkl

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Pfkl

Gene ID

18641

Gene namephosphofructokinase, liver, B-type
SynonymsAA407869|ATP-PFK|PFK-B|PFK-L
Cytomap10 C1|10 39.72 cM
Type of geneprotein-coding
DescriptionATP-dependent 6-phosphofructokinase, liver type6-phosphofructokinase type B6-phosphofructokinase, liver typephosphofructo-1-kinase isozyme Bphosphofructokinase 1phosphohexokinase
Modification date20220424
UniProtAcc

P12382


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Pfkl

GO:0003872

6-phosphofructokinase activity

21873635

Function
Pfkl

GO:0005524

ATP binding

21873635

Function
Pfkl

GO:0005945

6-phosphofructokinase complex

21873635

Component
Pfkl

GO:0006002

fructose 6-phosphate metabolic process

21873635

Process
Pfkl

GO:0016020

membrane

21873635

Component
Pfkl

GO:0016208

AMP binding

21873635

Function
Pfkl

GO:0030388

fructose 1,6-bisphosphate metabolic process

21873635

Process
Pfkl

GO:0042802

identical protein binding

21873635

Function
Pfkl

GO:0048029

monosaccharide binding

21873635

Function
Pfkl

GO:0061621

canonical glycolysis

21873635

Process
Pfkl

GO:0070095

fructose-6-phosphate binding

21873635

Function

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Spatial pattern events for Pfkl

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
PfklMouseBrainS1 344135152.07e-15
PfklMouseBrainS2 344135151.56e-15
PfklMouseBrainS3 344135151.64e-15
PfklMouseBrainS4 344135151.37e-15
PfklMouseBrainS6 344135151.46e-15
PfklMouseBrainS7 344135151.55e-15
PfklMouseBrain27A 326376221.06e-07
PfklMouseBrain27B 326376223.16e-09
PfklMouseBrain28A 326376225.83e-07
PfklMouseBrain28B 326376223.93e-10
PfklMouseBrain29B 326376223.56e-14
PfklMouseBrain31A 326376226.52e-07
PfklMouseBrainrep_2 351413741.69e-15
PfklMouseBrainrep_3 351413741.64e-15
PfklMouseBrainrep_4 351413741.57e-15
PfklMouseBrainrep_5 351413741.47e-15
PfklMouseBrainrep_6 351413741.73e-15
PfklMouseEmbryorep_13 331887761.09e-06
PfklMouseKidneyCLP 340037972.19e-15
PfklMouseKidneyIRI 340037972.29e-15
PfklMouseKidneySham 340037972.58e-15
PfklMouseKidneyrep_1 348531512.42e-15
PfklMouseKidneyrep_3 348531512.94e-15
PfklMouseKidneyrep_4 348531514.07e-15
PfklMouseKidneyrep_5 348531513.18e-15
PfklMouseBrainrep_1 334690251.30e-15
PfklMouseBrainrep_1 350277291.66e-15
PfklMouseBrainrep_2 350277291.57e-15
PfklMouseBrainrep_3 350277291.32e-15
PfklMouseBrainrep_4 350277291.76e-15
PfklMouseBrainrep_5 350277291.46e-15
PfklMouseBrainB02_E1 327023142.52e-11
PfklMouseLymphA1 03.29e-15
PfklMouseLymphB1 03.66e-15
PfklMouseLungrep_1 352908014.52e-15
PfklMouseLungrep_2 352908017.23e-15
PfklMouseLungrep_3 352908015.26e-15
PfklMouseLungrep_4 352908013.04e-15
PfklMouseBrainrep_2 352106243.17e-11

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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Kidney_rep_3_H&E
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Kidney_rep_4_H&E
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Kidney_rep_5_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_E1_H&E
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Lung_rep_1_H&E
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Lung_rep_2_H&E
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Lung_rep_3_H&E
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Lung_rep_4_H&E
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Spatial pattern pathway has Pfkl envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseSpinal cordCN94_E1 7.5e-07
PfklGOBP_Regulation_Of_TransportMouseSpinal cordCN94_E1 5.3e-07
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseSpinal cordL7bCN02_E1 8.3e-06
PfklGOBP_Hormone_TransportMouseSpinal cordL7bCN02_E1 3.7e-06
PfklGOBP_Nad_Metabolic_ProcessMouseSpinal cordL7bCN02_E1 6.6e-06
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseSpinal cordL7bCN02_E1 9.9e-06
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseSpinal cordL7bCN02_E1 7.1e-06
PfklGOBP_Regulation_Of_Hormone_SecretionMouseSpinal cordL7bCN02_E1 6.3e-07
PfklGOBP_Regulation_Of_Peptide_TransportMouseSpinal cordL7bCN02_E1 1.5e-06
PfklGOBP_Regulation_Of_SecretionMouseSpinal cordL7bCN02_E1 9.2e-07
PfklGOBP_Signal_ReleaseMouseSpinal cordL7bCN02_E1 4.2e-07
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.8e-07
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 4.6e-08
PfklGOBP_Cell_ActivationMouseSpinal cordL7CN45_C1 8.5e-07
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseSpinal cordL7CN45_C1 9.9e-07
PfklGOBP_Cell_Cell_SignalingMouseSpinal cordL7CN45_C1 3.5e-08
PfklGOBP_Establishment_Of_Protein_LocalizationMouseSpinal cordL7CN45_C1 4.4e-06
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 3.8e-07
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseSpinal cordL7CN45_C1 2.2e-08
PfklGOBP_Glucose_Catabolic_ProcessMouseSpinal cordL7CN45_C1 1.4e-06
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseSpinal cordL7CN45_C1 5.7e-06
PfklGOBP_Immune_Effector_ProcessMouseSpinal cordL7CN45_C1 3.1e-07
PfklGOBP_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 2.4e-06
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseSpinal cordL7CN45_C1 6.2e-09
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseSpinal cordL7CN45_C1 1.3e-07
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseSpinal cordL7CN45_C1 5.1e-06
PfklGOBP_Myeloid_Leukocyte_ActivationMouseSpinal cordL7CN45_C1 2.2e-07
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 6.7e-06
PfklGOBP_Nadh_Metabolic_ProcessMouseSpinal cordL7CN45_C1 5.2e-06
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseSpinal cordL7CN45_C1 5.9e-06
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseSpinal cordL7CN45_C1 4.2e-09
PfklGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.1e-07
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 2.3e-08
PfklGOBP_Organophosphate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 2.0e-07
PfklGOBP_Purine_Containing_Compound_Metabolic_ProcessMouseSpinal cordL7CN45_C1 3.7e-07
PfklGOBP_Regulation_Of_Hormone_LevelsMouseSpinal cordL7CN45_C1 9.1e-07
PfklGOBP_Regulation_Of_Ion_TransportMouseSpinal cordL7CN45_C1 3.6e-07
PfklGOBP_Response_To_CarbohydrateMouseSpinal cordL7CN45_C1 1.2e-09
PfklGOBP_Response_To_MonosaccharideMouseSpinal cordL7CN45_C1 6.7e-07
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 8.5e-07
PfklGOBP_SecretionMouseSpinal cordL7CN45_C1 8.1e-09
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseSpinal cordL7CN45_C1 4.6e-07
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.7e-07
PfklGOBP_ExocytosisMouseSpinal cordL7CN47_C1 7.4e-07
PfklGOBP_Negative_Regulation_Of_SecretionMouseSpinal cordL7CN47_C1 1.5e-07
PfklGOBP_Atp_Metabolic_ProcessMouseSpinal cordL7CN47_D1 3.0e-06
PfklGOBP_Insulin_SecretionMouseSpinal cordL7CN47_D1 7.1e-06
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseSpinal cordL7CN85_E1 9.2e-07
PfklGOBP_Regulation_Of_Protein_LocalizationMouseSpinal cordL8CN14_E2 3.4e-12
PfklGOBP_Negative_Regulation_Of_SignalingMouseSpinal cordL8CN17_E1 8.3e-06
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_27 3.0e-05
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseBrainrep_27 1.1e-06
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseBrainrep_27 1.0e-05
PfklGOBP_Negative_Regulation_Of_SecretionMouseBrainrep_27 3.7e-06
PfklGOBP_Regulation_Of_SecretionMouseBrainrep_27 2.9e-06
PfklGOBP_SecretionMouseBrainrep_27 8.9e-05
PfklGOBP_Atp_Metabolic_ProcessMouseBrainrep_71 2.7e-06
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseBrainrep_71 8.0e-05
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainrep_71 2.1e-06
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseBrainrep_71 8.1e-05
PfklGOBP_Nadh_Metabolic_ProcessMouseBrainrep_71 1.0e-05
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseBrainrep_71 4.8e-05
PfklGOBP_Pyruvate_Metabolic_ProcessMouseBrainrep_71 1.3e-05
PfklGOBP_Cell_ActivationMouseBrainrep_72 4.6e-06
PfklGOBP_Atp_Metabolic_ProcessMouseBrainrep_1 2.0e-14
PfklGOBP_Cell_ActivationMouseBrainrep_1 1.8e-07
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_1 2.6e-13
PfklGOBP_Cell_Cell_SignalingMouseBrainrep_1 5.1e-48
PfklGOBP_Establishment_Of_Protein_LocalizationMouseBrainrep_1 6.6e-07
PfklGOBP_ExocytosisMouseBrainrep_1 3.4e-73
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseBrainrep_1 1.8e-08
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainrep_1 5.4e-15
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseBrainrep_1 3.0e-08
PfklGOBP_Immune_Effector_ProcessMouseBrainrep_1 1.5e-12
PfklGOBP_Insulin_SecretionMouseBrainrep_1 1.7e-59
PfklGOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_1 2.1e-07
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_1 1.3e-13
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseBrainrep_1 3.2e-09
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseBrainrep_1 8.8e-72
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseBrainrep_1 4.8e-33
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseBrainrep_1 1.4e-71
PfklGOBP_Negative_Regulation_Of_TransportMouseBrainrep_1 1.2e-09
PfklGOBP_Nucleotide_PhosphorylationMouseBrainrep_1 3.5e-07
PfklGOBP_Regulation_Of_Hormone_SecretionMouseBrainrep_1 8.1e-70
PfklGOBP_Regulation_Of_Ion_TransportMouseBrainrep_1 8.9e-34
PfklGOBP_Regulation_Of_Peptide_TransportMouseBrainrep_1 1.1e-56
PfklGOBP_Regulation_Of_Protein_LocalizationMouseBrainrep_1 2.2e-07
PfklGOBP_Regulation_Of_SecretionMouseBrainrep_1 2.0e-20
PfklGOBP_Regulation_Of_TransportMouseBrainrep_1 3.9e-15
PfklGOBP_Response_To_MonosaccharideMouseBrainrep_1 1.8e-15
PfklGOBP_SecretionMouseBrainrep_1 4.1e-45
PfklGOBP_Signal_ReleaseMouseBrainrep_1 4.7e-44
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseBrainrep_3 5.9e-70
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseBrainrep_3 4.5e-61
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseBrainrep_3 1.4e-74
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseBrainrep_3 2.5e-36
PfklGOBP_Glucose_Catabolic_ProcessMouseBrainrep_3 1.5e-38
PfklGOBP_Glucose_Metabolic_ProcessMouseBrainrep_3 6.3e-54
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseBrainrep_33.2e-119
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseBrainrep_3 2.0e-31
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseBrainrep_3 9.2e-62
PfklGOBP_Nad_Metabolic_ProcessMouseBrainrep_3 3.2e-22
PfklGOBP_Nadh_Metabolic_ProcessMouseBrainrep_3 2.6e-65
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseBrainrep_39.7e-201
PfklGOBP_Negative_Regulation_Of_SignalingMouseBrainrep_37.8e-106
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseBrainrep_3 7.0e-63
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseBrainrep_31.5e-154
PfklGOBP_Organophosphate_Metabolic_ProcessMouseBrainrep_3 8.1e-43
PfklGOBP_Pyruvate_Metabolic_ProcessMouseBrainrep_3 4.4e-42
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 6.3e-92
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseBrainrep_39.8e-142
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseBrainrep_3 2.7e-19
PfklGOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.3e-32
PfklGOBP_Response_To_CarbohydrateMouseBrainrep_4 6.0e-07
PfklGOBP_Negative_Regulation_Of_SecretionMouseBrainrep_7 1.9e-53
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_6 1.4e-16
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseEmbryorep_6 1.1e-16
PfklGOBP_Negative_Regulation_Of_SecretionMouseEmbryorep_6 3.4e-14
PfklGOBP_Atp_Metabolic_ProcessMouseEmbryorep_14 3.7e-37
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseEmbryorep_14 2.1e-54
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseEmbryorep_14 1.1e-08
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseEmbryorep_14 8.9e-67
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseEmbryorep_14 4.4e-67
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseEmbryorep_14 2.9e-37
PfklGOBP_Glucose_Catabolic_ProcessMouseEmbryorep_14 2.4e-62
PfklGOBP_Glucose_Metabolic_ProcessMouseEmbryorep_14 1.4e-21
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseEmbryorep_14 2.8e-78
PfklGOBP_Immune_Effector_ProcessMouseEmbryorep_14 3.3e-15
PfklGOBP_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 3.8e-12
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseEmbryorep_14 7.3e-13
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseEmbryorep_14 1.3e-52
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseEmbryorep_14 3.9e-21
PfklGOBP_Myeloid_Leukocyte_ActivationMouseEmbryorep_14 2.9e-28
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 1.7e-32
PfklGOBP_Nad_Metabolic_ProcessMouseEmbryorep_14 2.4e-39
PfklGOBP_Nadh_Metabolic_ProcessMouseEmbryorep_14 1.6e-53
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseEmbryorep_14 6.4e-12
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseEmbryorep_14 6.6e-21
PfklGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessMouseEmbryorep_14 1.8e-12
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseEmbryorep_14 2.3e-36
PfklGOBP_Nucleotide_PhosphorylationMouseEmbryorep_14 1.3e-42
PfklGOBP_Organophosphate_Metabolic_ProcessMouseEmbryorep_14 2.0e-09
PfklGOBP_Purine_Containing_Compound_Metabolic_ProcessMouseEmbryorep_14 6.5e-20
PfklGOBP_Pyruvate_Metabolic_ProcessMouseEmbryorep_14 3.2e-54
PfklGOBP_Regulation_Of_Anion_TransportMouseEmbryorep_14 1.3e-71
PfklGOBP_Response_To_MonosaccharideMouseEmbryorep_14 2.3e-08
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseEmbryorep_14 7.6e-14
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseEmbryorep_1 5.6e-24
PfklGOBP_Glucose_Metabolic_ProcessMouseEmbryorep_19.4e-142
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseEmbryorep_1 6.0e-95
PfklGOBP_Negative_Regulation_Of_SignalingMouseEmbryorep_1 5.6e-10
PfklGOBP_Regulation_Of_Hormone_LevelsMouseEmbryorep_14.1e-102
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseEmbryorep_1 1.4e-55
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_2 3.4e-34
PfklGOBP_Immune_Effector_ProcessMouseEmbryorep_2 1.7e-23
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseEmbryorep_3 1.4e-07
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseEmbryorep_32.9e-170
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseEmbryorep_4 0.0e+00
PfklGOBP_Negative_Regulation_Of_SecretionMouseEmbryorep_4 1.1e-61
PfklGOBP_Negative_Regulation_Of_TransportMouseEmbryorep_4 7.5e-23
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyNep 4.2e-26
PfklGOBP_Regulation_Of_Protein_LocalizationMouseKidneyNep 1.1e-16
PfklGOBP_Regulation_Of_TransportMouseKidneyNep 2.6e-47
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyNep 6.8e-28
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseKidneyrep_22.8e-126
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseKidneyrep_2 2.5e-42
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseKidneyrep_2 5.2e-99
PfklGOBP_Cell_ActivationMouseKidneyrep_2 5.1e-83
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseKidneyrep_24.3e-101
PfklGOBP_Cell_Cell_SignalingMouseKidneyrep_2 6.2e-72
PfklGOBP_Establishment_Of_Protein_LocalizationMouseKidneyrep_2 9.8e-86
PfklGOBP_ExocytosisMouseKidneyrep_23.2e-107
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseKidneyrep_26.9e-118
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseKidneyrep_2 1.0e-69
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseKidneyrep_2 3.3e-14
PfklGOBP_Glucose_Metabolic_ProcessMouseKidneyrep_22.6e-109
PfklGOBP_Hormone_TransportMouseKidneyrep_2 2.4e-23
PfklGOBP_Immune_Effector_ProcessMouseKidneyrep_23.4e-107
PfklGOBP_Insulin_SecretionMouseKidneyrep_25.3e-102
PfklGOBP_Leukocyte_Mediated_ImmunityMouseKidneyrep_22.7e-133
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseKidneyrep_2 4.4e-73
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseKidneyrep_2 1.7e-42
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseKidneyrep_24.3e-127
PfklGOBP_Myeloid_Leukocyte_ActivationMouseKidneyrep_22.2e-110
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyrep_26.6e-105
PfklGOBP_Nad_Metabolic_ProcessMouseKidneyrep_21.1e-173
PfklGOBP_Nadh_Metabolic_ProcessMouseKidneyrep_22.1e-128
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseKidneyrep_2 3.4e-49
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseKidneyrep_2 5.1e-33
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseKidneyrep_2 1.1e-25
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseKidneyrep_2 3.2e-14
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseKidneyrep_2 2.8e-13
PfklGOBP_Negative_Regulation_Of_SignalingMouseKidneyrep_2 4.0e-40
PfklGOBP_Negative_Regulation_Of_TransportMouseKidneyrep_2 4.0e-19
PfklGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessMouseKidneyrep_2 2.4e-27
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseKidneyrep_21.5e-102
PfklGOBP_Nucleotide_PhosphorylationMouseKidneyrep_2 2.4e-99
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseKidneyrep_2 3.8e-62
PfklGOBP_Organophosphate_Metabolic_ProcessMouseKidneyrep_2 1.7e-41
PfklGOBP_Purine_Containing_Compound_Metabolic_ProcessMouseKidneyrep_2 2.5e-17
PfklGOBP_Pyruvate_Metabolic_ProcessMouseKidneyrep_2 3.6e-95
PfklGOBP_Regulation_Of_Anion_TransportMouseKidneyrep_25.2e-139
PfklGOBP_Regulation_Of_Hormone_LevelsMouseKidneyrep_2 6.8e-73
PfklGOBP_Regulation_Of_Hormone_SecretionMouseKidneyrep_2 1.0e-09
PfklGOBP_Regulation_Of_Ion_TransportMouseKidneyrep_25.5e-106
PfklGOBP_Regulation_Of_Peptide_TransportMouseKidneyrep_2 1.1e-18
PfklGOBP_Regulation_Of_Protein_LocalizationMouseKidneyrep_2 1.5e-38
PfklGOBP_Regulation_Of_SecretionMouseKidneyrep_2 4.7e-24
PfklGOBP_Regulation_Of_TransportMouseKidneyrep_2 2.4e-58
PfklGOBP_Response_To_CarbohydrateMouseKidneyrep_2 6.9e-74
PfklGOBP_Response_To_MonosaccharideMouseKidneyrep_2 8.2e-43
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_26.6e-112
PfklGOBP_SecretionMouseKidneyrep_2 1.6e-23
PfklGOBP_Signal_ReleaseMouseKidneyrep_2 2.9e-40
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseKidneyrep_2 4.4e-89
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseKidneyrep_2 1.8e-43
PfklGOBP_Regulation_Of_Anion_TransportMouseLiverCN16-D1 7.0e-08
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseLiverCN16-D2 7.1e-07
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseLiverCN16-D2 7.7e-08
PfklGOBP_Insulin_SecretionMouseLiverCN16-D2 1.8e-11
PfklGOBP_Nadh_Metabolic_ProcessMouseLiverCN16-D2 4.3e-07
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseLiverCN16-D2 3.3e-07
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseLiverCN16-D2 5.9e-07
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseLiverCN16-D2 1.1e-07
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseLiverCN16-E1 4.9e-08
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseLiverCN73-C1 5.1e-08
PfklGOBP_Glucose_Catabolic_ProcessMouseLiverCN73-C1 3.5e-15
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseLiverCN73-C1 2.7e-15
PfklGOBP_Hormone_TransportMouseLiverCN73-C1 1.6e-07
PfklGOBP_Nad_Metabolic_ProcessMouseLiverCN73-C1 6.5e-09
PfklGOBP_Regulation_Of_Hormone_SecretionMouseLiverCN73-C1 8.3e-12
PfklGOBP_Regulation_Of_Peptide_TransportMouseLiverCN73-C1 2.7e-07
PfklGOBP_Regulation_Of_TransportMouseLiverCN73-C1 1.8e-07
PfklGOBP_Signal_ReleaseMouseLiverCN73-C1 5.6e-09
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseLiverrep_15 3.9e-29
PfklGOBP_Myeloid_Leukocyte_ActivationMouseLiverrep_15 2.4e-09
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseLiverrep_15 4.1e-21
PfklGOBP_Atp_Metabolic_ProcessMouseLiverrep_16 1.2e-30
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLiverrep_16 1.6e-18
PfklGOBP_ExocytosisMouseLiverrep_16 8.5e-07
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseLiverrep_16 7.4e-11
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLiverrep_16 2.2e-20
PfklGOBP_Nad_Metabolic_ProcessMouseLiverrep_16 1.6e-07
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseLiverrep_16 1.7e-08
PfklGOBP_Negative_Regulation_Of_SecretionMouseLiverrep_16 1.0e-12
PfklGOBP_Pyruvate_Metabolic_ProcessMouseLiverrep_16 8.6e-09
PfklGOBP_Regulation_Of_Anion_TransportMouseLiverrep_16 1.8e-07
PfklGOBP_Response_To_CarbohydrateMouseLiverrep_23 6.8e-09
PfklGOBP_Response_To_MonosaccharideMouseLiverrep_23 1.3e-10
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseLymphMS-1 1.6e-09
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseLymphMS-1 2.8e-10
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseLymphMS-1 5.9e-10
PfklGOBP_Cell_ActivationMouseLymphMS-1 1.6e-18
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLymphMS-1 9.7e-16
PfklGOBP_Cell_Cell_SignalingMouseLymphMS-1 9.7e-11
PfklGOBP_Establishment_Of_Protein_LocalizationMouseLymphMS-1 2.5e-11
PfklGOBP_ExocytosisMouseLymphMS-1 1.4e-14
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseLymphMS-1 1.4e-11
PfklGOBP_Glucose_Metabolic_ProcessMouseLymphMS-1 1.3e-09
PfklGOBP_Hormone_TransportMouseLymphMS-1 3.2e-13
PfklGOBP_Immune_Effector_ProcessMouseLymphMS-1 1.6e-18
PfklGOBP_Insulin_SecretionMouseLymphMS-1 6.6e-10
PfklGOBP_Leukocyte_Mediated_ImmunityMouseLymphMS-1 5.6e-21
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseLymphMS-1 1.3e-15
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseLymphMS-1 9.5e-09
PfklGOBP_Myeloid_Leukocyte_ActivationMouseLymphMS-1 1.0e-18
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLymphMS-1 6.6e-07
PfklGOBP_Nad_Metabolic_ProcessMouseLymphMS-1 1.4e-10
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseLymphMS-1 7.6e-11
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseLymphMS-1 1.9e-10
PfklGOBP_Negative_Regulation_Of_Ion_TransportMouseLymphMS-1 2.0e-07
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseLymphMS-1 5.9e-19
PfklGOBP_Negative_Regulation_Of_SecretionMouseLymphMS-1 3.1e-23
PfklGOBP_Negative_Regulation_Of_SignalingMouseLymphMS-1 1.0e-14
PfklGOBP_Negative_Regulation_Of_TransportMouseLymphMS-1 1.0e-17
PfklGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessMouseLymphMS-1 2.7e-09
PfklGOBP_Nucleotide_PhosphorylationMouseLymphMS-1 1.4e-07
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseLymphMS-1 1.3e-15
PfklGOBP_Organophosphate_Metabolic_ProcessMouseLymphMS-1 7.3e-07
PfklGOBP_Purine_Containing_Compound_Metabolic_ProcessMouseLymphMS-1 8.0e-08
PfklGOBP_Pyruvate_Metabolic_ProcessMouseLymphMS-1 7.1e-07
PfklGOBP_Regulation_Of_Anion_TransportMouseLymphMS-1 4.5e-13
PfklGOBP_Regulation_Of_Hormone_LevelsMouseLymphMS-1 1.6e-16
PfklGOBP_Regulation_Of_Hormone_SecretionMouseLymphMS-1 1.4e-11
PfklGOBP_Regulation_Of_Ion_TransportMouseLymphMS-1 1.5e-09
PfklGOBP_Regulation_Of_Peptide_TransportMouseLymphMS-1 2.3e-19
PfklGOBP_Regulation_Of_Protein_LocalizationMouseLymphMS-1 1.3e-07
PfklGOBP_Regulation_Of_SecretionMouseLymphMS-1 6.9e-23
PfklGOBP_Regulation_Of_TransportMouseLymphMS-1 1.4e-12
PfklGOBP_Response_To_CarbohydrateMouseLymphMS-1 3.0e-14
PfklGOBP_Response_To_MonosaccharideMouseLymphMS-1 2.2e-12
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 1.8e-09
PfklGOBP_SecretionMouseLymphMS-1 2.3e-12
PfklGOBP_Signal_ReleaseMouseLymphMS-1 6.4e-13
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseLymphMS-1 5.1e-07
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseLymphMS-1 2.6e-11
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseLymphPBS 1.2e-08
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseLymphPBS 4.2e-08
PfklGOBP_Glucose_Catabolic_ProcessMouseLungrep_1 8.1e-08
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseLungrep_1 1.2e-19
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseBrainrep_4 8.7e-07
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_4 2.9e-33
PfklGOBP_ExocytosisMouseBrainrep_4 2.4e-43
PfklGOBP_Glucose_Catabolic_ProcessMouseBrainrep_4 5.5e-55
PfklGOBP_Glycolytic_Process_Through_Fructose_6_PhosphateMouseBrainrep_4 7.6e-45
PfklGOBP_Immune_Effector_ProcessMouseBrainrep_4 7.2e-15
PfklGOBP_Insulin_SecretionMouseBrainrep_4 2.3e-23
PfklGOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 6.4e-19
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseBrainrep_4 8.7e-29
PfklGOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_4 3.5e-20
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.7e-62
PfklGOBP_Nad_Metabolic_ProcessMouseBrainrep_4 7.2e-54
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseBrainrep_4 2.6e-58
PfklGOBP_Regulation_Of_Anion_TransportMouseBrainrep_4 2.4e-47
PfklGOBP_Regulation_Of_Hormone_SecretionMouseBrainrep_4 1.0e-07
PfklGOBP_Regulation_Of_SecretionMouseBrainrep_4 5.7e-16
PfklGOBP_Response_To_CarbohydrateMouseBrainrep_4 1.6e-11
PfklGOBP_Signal_ReleaseMouseBrainrep_4 6.4e-31
PfklGOBP_Nadh_Metabolic_ProcessMouseBrainrep_7 1.2e-41
PfklGOBP_Fructose_6_Phosphate_Metabolic_ProcessMouseBrainHP_ad_rep3 3.2e-07
PfklGOBP_Cell_Cell_SignalingMouseBrainHP_ad_rep7 1.6e-08
PfklGOBP_Establishment_Of_Protein_LocalizationMouseBrainHP_ad_rep7 8.7e-10
PfklGOBP_Monosaccharide_Catabolic_ProcessMouseBrainHP_ad_rep7 1.3e-13
PfklGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainHP_ad_rep7 4.4e-14
PfklGOBP_Negative_Regulation_Of_Establishment_Of_Protein_LocalizationMouseBrainHP_ad_rep7 3.3e-08
PfklGOBP_Negative_Regulation_Of_SecretionMouseBrainHP_ad_rep7 4.1e-10
PfklGOBP_Negative_Regulation_Of_TransportMouseBrainHP_ad_rep7 1.7e-07
PfklGOBP_Organic_Acid_Metabolic_ProcessMouseBrainHP_ad_rep7 4.1e-08
PfklGOBP_Regulation_Of_Anion_TransportMouseBrainHP_ad_rep7 2.1e-07
PfklGOBP_Regulation_Of_Protein_LocalizationMouseBrainHP_ad_rep7 1.1e-09
PfklGOBP_Regulation_Of_SecretionMouseBrainHP_ad_rep7 1.9e-11
PfklGOBP_Regulation_Of_TransportMouseBrainHP_ad_rep7 9.2e-09
PfklGOBP_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 4.2e-09
PfklGOBP_SecretionMouseBrainHP_ad_rep7 1.6e-08
PfklGOBP_Signal_ReleaseMouseBrainHP_ad_rep7 6.3e-07
PfklGOBP_Small_Molecule_Catabolic_ProcessMouseBrainHP_ad_rep7 2.3e-11
PfklGOBP_Fructose_1_6_Bisphosphate_Metabolic_ProcessMouseBrainHP_polb_rep3 2.4e-07
PfklGOBP_Atp_Metabolic_ProcessMouseBrainHP_polb_rep9 1.0e-11
PfklGOBP_Carbohydrate_Catabolic_ProcessMouseBrainHP_polb_rep9 1.6e-10
PfklGOBP_Carbohydrate_Derivative_Metabolic_ProcessMouseBrainHP_polb_rep9 5.2e-12
PfklGOBP_Carbohydrate_Metabolic_ProcessMouseBrainHP_polb_rep9 1.6e-09
PfklGOBP_Cell_ActivationMouseBrainHP_polb_rep9 1.5e-08
PfklGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainHP_polb_rep9 8.8e-09
PfklGOBP_ExocytosisMouseBrainHP_polb_rep9 2.3e-13
PfklGOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainHP_polb_rep9 5.4e-11
PfklGOBP_Glucose_Metabolic_ProcessMouseBrainHP_polb_rep9 1.8e-10
PfklGOBP_Hormone_TransportMouseBrainHP_polb_rep9 3.6e-07
PfklGOBP_Immune_Effector_ProcessMouseBrainHP_polb_rep9 1.0e-08
PfklGOBP_Insulin_SecretionMouseBrainHP_polb_rep9 3.6e-09
PfklGOBP_Leukocyte_Mediated_ImmunityMouseBrainHP_polb_rep9 2.8e-07
PfklGOBP_Monocarboxylic_Acid_Metabolic_ProcessMouseBrainHP_polb_rep9 1.7e-11
PfklGOBP_Monosaccharide_Metabolic_ProcessMouseBrainHP_polb_rep9 1.7e-09
PfklGOBP_Myeloid_Leukocyte_ActivationMouseBrainHP_polb_rep9 2.6e-11
PfklGOBP_Nad_Metabolic_ProcessMouseBrainHP_polb_rep9 3.5e-07
PfklGOBP_Nadh_Metabolic_ProcessMouseBrainHP_polb_rep9 4.8e-10
PfklGOBP_Negative_Regulation_Of_Anion_TransportMouseBrainHP_polb_rep9 7.0e-09
PfklGOBP_Negative_Regulation_Of_SignalingMouseBrainHP_polb_rep9 1.4e-11
PfklGOBP_Nucleobase_Containing_Small_Molecule_Metabolic_ProcessMouseBrainHP_polb_rep9 6.9e-09
PfklGOBP_Nucleoside_Diphosphate_Metabolic_ProcessMouseBrainHP_polb_rep9 3.2e-13
PfklGOBP_Nucleotide_PhosphorylationMouseBrainHP_polb_rep9 5.7e-10
PfklGOBP_Organophosphate_Metabolic_ProcessMouseBrainHP_polb_rep9 7.1e-09
PfklGOBP_Purine_Containing_Compound_Metabolic_ProcessMouseBrainHP_polb_rep9 9.4e-07
PfklGOBP_Pyruvate_Metabolic_ProcessMouseBrainHP_polb_rep9 6.5e-09
PfklGOBP_Regulation_Of_Hormone_LevelsMouseBrainHP_polb_rep9 9.1e-09
PfklGOBP_Regulation_Of_Hormone_SecretionMouseBrainHP_polb_rep9 4.8e-14
PfklGOBP_Regulation_Of_Peptide_TransportMouseBrainHP_polb_rep9 6.8e-12
PfklGOBP_Response_To_CarbohydrateMouseBrainHP_polb_rep9 3.2e-07
PfklGOBP_Response_To_MonosaccharideMouseBrainHP_polb_rep9 4.5e-09
PfklGOBP_Small_Molecule_Metabolic_ProcessMouseBrainHP_polb_rep9 2.0e-09
PfklGOBP_Negative_Regulation_Of_Hormone_SecretionMouseBrainHP_wt_rep2 1.8e-13
PfklGOBP_Negative_Regulation_Of_Peptide_SecretionMouseBrainHP_wt_rep2 3.6e-11

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Pfkl function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Pfkl function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Pfkl envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Pfkl

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Pfkl

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
PfklC0005586Bipolar Disorder5PSYGENET
PfklC0525045Mood Disorders1PSYGENET