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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Peg3 (spascer ID:18616)

Gene summary for Peg3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Peg3
	Gene ID	18616
	Gene name	paternally expressed 3
	Synonyms	AL022617\|ASF-1\|End4\|Gcap4\|Pw1\|Zfp102\|mKIAA0287
	Cytomap	7 A1\|7 3.89 cM
	Type of gene	protein-coding
	Description	paternally-expressed gene 3 proteingranule cell antiserum positive 4paternally expressed gene 3
	Modification date	20220424
	UniProtAcc	Q3URU2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Peg3	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	21873635	Function
Peg3	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
Peg3	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	21873635	Function
Peg3	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for Peg3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Peg3	Mouse	Brain	S1	34413515	2.07e-15
Peg3	Mouse	Brain	S2	34413515	1.56e-15
Peg3	Mouse	Brain	S3	34413515	1.64e-15
Peg3	Mouse	Brain	S4	34413515	1.37e-15
Peg3	Mouse	Brain	S6	34413515	1.46e-15
Peg3	Mouse	Brain	S7	34413515	1.55e-15
Peg3	Mouse	Brain	06A	32637622	3.25e-11
Peg3	Mouse	Brain	06B	32637622	3.07e-09
Peg3	Mouse	Brain	07A	32637622	2.42e-08
Peg3	Mouse	Brain	07B	32637622	6.83e-12
Peg3	Mouse	Brain	08B	32637622	5.71e-14
Peg3	Mouse	Brain	09A	32637622	1.25e-11
Peg3	Mouse	Brain	09B	32637622	5.79e-14
Peg3	Mouse	Brain	10A	32637622	9.51e-13
Peg3	Mouse	Brain	10B	32637622	7.15e-12
Peg3	Mouse	Brain	11A	32637622	1.61e-14
Peg3	Mouse	Brain	12A	32637622	2.09e-14
Peg3	Mouse	Brain	12B	32637622	1.20e-14
Peg3	Mouse	Brain	13A	32637622	5.42e-06
Peg3	Mouse	Brain	13B	32637622	1.72e-14
Peg3	Mouse	Brain	14A	32637622	1.38e-14
Peg3	Mouse	Brain	14B	32637622	1.35e-14
Peg3	Mouse	Brain	15A	32637622	1.66e-12
Peg3	Mouse	Brain	15B	32637622	2.07e-14
Peg3	Mouse	Brain	16A	32637622	1.75e-14
Peg3	Mouse	Brain	16B	32637622	2.21e-14
Peg3	Mouse	Brain	17A	32637622	1.19e-14
Peg3	Mouse	Brain	17B	32637622	1.32e-14
Peg3	Mouse	Brain	18A	32637622	1.20e-14
Peg3	Mouse	Brain	18B	32637622	1.38e-14
Peg3	Mouse	Brain	19A	32637622	1.35e-14
Peg3	Mouse	Brain	19B	32637622	1.36e-14
Peg3	Mouse	Brain	20A	32637622	1.49e-14
Peg3	Mouse	Brain	20B	32637622	1.86e-14
Peg3	Mouse	Brain	21A	32637622	1.43e-14
Peg3	Mouse	Brain	21B	32637622	1.37e-14
Peg3	Mouse	Brain	22A	32637622	8.87e-15
Peg3	Mouse	Brain	22B	32637622	8.81e-15
Peg3	Mouse	Brain	23A	32637622	1.72e-14
Peg3	Mouse	Brain	23B	32637622	1.10e-14
Peg3	Mouse	Brain	24A	32637622	1.61e-14
Peg3	Mouse	Brain	24B	32637622	1.40e-14
Peg3	Mouse	Brain	25A	32637622	1.96e-11
Peg3	Mouse	Brain	26A	32637622	1.34e-14
Peg3	Mouse	Brain	26B	32637622	3.04e-14
Peg3	Mouse	Brain	27A	32637622	1.03e-14
Peg3	Mouse	Brain	27B	32637622	1.06e-14
Peg3	Mouse	Brain	28A	32637622	1.06e-14
Peg3	Mouse	Brain	28B	32637622	1.24e-14
Peg3	Mouse	Brain	29A	32637622	1.08e-14
Peg3	Mouse	Brain	29B	32637622	1.08e-14
Peg3	Mouse	Brain	30A	32637622	1.48e-14
Peg3	Mouse	Brain	31A	32637622	1.59e-14
Peg3	Mouse	Brain	32A	32637622	1.52e-14
Peg3	Mouse	Brain	33A	32637622	1.50e-14
Peg3	Mouse	Brain	33B	32637622	1.94e-14
Peg3	Mouse	Brain	34A	32637622	1.42e-14
Peg3	Mouse	Brain	34B	32637622	1.67e-14
Peg3	Mouse	Brain	35A	32637622	1.48e-14
Peg3	Mouse	Brain	35B	32637622	1.78e-14
Peg3	Mouse	Brain	36A	32637622	7.40e-14
Peg3	Mouse	Brain	36B	32637622	4.83e-14
Peg3	Mouse	Brain	37A	32637622	1.31e-10
Peg3	Mouse	Brain	38A	32637622	8.68e-11
Peg3	Mouse	Brain	38B	32637622	6.59e-14
Peg3	Mouse	Brain	39A	32637622	1.34e-09
Peg3	Mouse	Brain	rep_1	35141374	2.02e-15
Peg3	Mouse	Brain	rep_2	35141374	1.69e-15
Peg3	Mouse	Brain	rep_3	35141374	1.64e-15
Peg3	Mouse	Brain	rep_4	35141374	1.57e-15
Peg3	Mouse	Brain	rep_5	35141374	1.47e-15
Peg3	Mouse	Brain	rep_6	35141374	1.73e-15
Peg3	Mouse	Embryo	1D	34210887	2.16e-11
Peg3	Mouse	Embryo	1E	34210887	7.50e-15
Peg3	Mouse	Embryo	1F	34210887	1.30e-14
Peg3	Mouse	Embryo	1G	34210887	6.15e-15
Peg3	Mouse	Embryo	2H	34210887	5.31e-15
Peg3	Mouse	Embryo	3D	34210887	1.50e-14
Peg3	Mouse	Embryo	3F	34210887	5.82e-15
Peg3	Mouse	Embryo	3G	34210887	8.80e-15
Peg3	Mouse	Embryo	3H	34210887	5.89e-14
Peg3	Mouse	Embryo	4A	34210887	2.38e-14
Peg3	Mouse	Embryo	4C	34210887	1.65e-14
Peg3	Mouse	Embryo	4D	34210887	7.75e-15
Peg3	Mouse	Embryo	4E	34210887	4.53e-15
Peg3	Mouse	Embryo	rep_1	33188776	9.94e-15
Peg3	Mouse	Embryo	rep_2	33188776	1.37e-14
Peg3	Mouse	Embryo	rep_3	33188776	1.13e-14
Peg3	Mouse	Embryo	rep_4	33188776	5.08e-15
Peg3	Mouse	Embryo	rep_5	33188776	1.40e-14
Peg3	Mouse	Embryo	rep_6	33188776	1.27e-14
Peg3	Mouse	Embryo	rep_7	33188776	6.94e-15
Peg3	Mouse	Embryo	rep_12	33188776	4.84e-15
Peg3	Mouse	Embryo	rep_13	33188776	4.49e-15
Peg3	Mouse	Embryo	rep_14	33188776	2.14e-14
Peg3	Mouse	Embryo	rep_15	33188776	5.97e-15
Peg3	Mouse	Kidney	CLP	34003797	3.79e-08
Peg3	Mouse	Kidney	rep_3	33976190	2.75e-11
Peg3	Mouse	Kidney	rep_4	33976190	2.09e-09
Peg3	Mouse	Brain	rep_1	33469025	1.30e-15
Peg3	Mouse	Brain	rep_1	35027729	1.66e-15
Peg3	Mouse	Brain	rep_2	35027729	1.57e-15
Peg3	Mouse	Brain	rep_3	35027729	1.32e-15
Peg3	Mouse	Brain	rep_4	35027729	1.76e-15
Peg3	Mouse	Brain	rep_5	35027729	1.46e-15
Peg3	Mouse	Brain	B02_D1	32702314	1.50e-14
Peg3	Mouse	Brain	B02_E1	32702314	1.33e-14
Peg3	Mouse	Brain	B03_C2	32702314	3.45e-14
Peg3	Mouse	Brain	B03_D2	32702314	2.13e-14
Peg3	Mouse	Brain	B04_D1	32702314	6.50e-14
Peg3	Mouse	Brain	B04_E1	32702314	5.34e-08
Peg3	Mouse	Brain	B05_D2	32702314	7.75e-14
Peg3	Mouse	Brain	B05_E2	32702314	4.11e-14
Peg3	Mouse	Brain	B06_E1	32702314	4.32e-14
Peg3	Mouse	Brain	B07_C2	32702314	3.09e-14
Peg3	Mouse	Brain	N02_C1	32702314	3.13e-14
Peg3	Mouse	Brain	N02_D1	32702314	2.44e-14
Peg3	Mouse	Brain	N03_C2	32702314	2.55e-14
Peg3	Mouse	Brain	N03_D2	32702314	1.38e-14
Peg3	Mouse	Brain	N04_D1	32702314	3.34e-14
Peg3	Mouse	Brain	N04_E1	32702314	3.65e-14
Peg3	Mouse	Brain	N05_C2	32702314	1.01e-13
Peg3	Mouse	Brain	N05_D2	32702314	1.93e-14
Peg3	Mouse	Brain	N07_C1	32702314	3.68e-14
Peg3	Mouse	Brain	rep_1	35210624	1.74e-15
Peg3	Mouse	Brain	rep_2	35210624	1.74e-15
Peg3	Mouse	Brain	rep_3	35210624	1.82e-15
Peg3	Mouse	Brain	rep_4	35210624	2.34e-15
Peg3	Mouse	Brain	rep_5	35210624	2.07e-15
Peg3	Mouse	Brain	rep_6	35210624	2.05e-15
Peg3	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_D1_H&E
Brain_B04_E1_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Brain_B06_E1_H&E
Brain_B07_C2_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Brain_N07_C1_H&E

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Spatial pattern pathway has Peg3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	CN94_E1	2.2e-06
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_27	2.8e-05
Peg3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_3	7.5e-168
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Peg3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	2.2e-14
Peg3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	2.2e-09
Peg3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Peg3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Peg3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Peg3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.1e-13
Peg3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Peg3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11

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Peg3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Peg3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Peg3 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
PEG3	Intestine	development	Fibroblasts	PIEZO2,SLIT2,ADAMTSL3, etc.	0.494
PEG3	Intestine	development	MyoFibroblasts	PIEZO2,SLIT2,ADAMTSL3, etc.	0.273
PEG3	Intestine	development	Neural	PIEZO2,SLIT2,ADAMTSL3, etc.	0.253
PEG3	Intestine	development	Muscularis	PIEZO2,SLIT2,ADAMTSL3, etc.	0.265

Motif information.

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Related Drugs for Peg3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Peg3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Peg3	C0023897	Liver Diseases, Parasitic	1	CTD_human
Peg3	C0206698	Cholangiocarcinoma	1	CTD_human
Peg3	C0345905	Intrahepatic Cholangiocarcinoma	1	CTD_human
Peg3	C3805278	Extrahepatic Cholangiocarcinoma	1	CTD_human