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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pde7a (spascer ID:18583)

Gene summary for Pde7a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pde7a
	Gene ID	18583
	Gene name	phosphodiesterase 7A
	Synonyms	AU015378\|AW047537
	Cytomap	3 A2\|3 5.36 cM
	Type of gene	protein-coding
	Description	high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
	Modification date	20220424
	UniProtAcc	P70453

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pde7a	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	21873635	Function
Pde7a	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	21873635	Function
Pde7a	GO:0007165	signal transduction	21873635	Process
Pde7a	GO:0019933	cAMP-mediated signaling	21873635	Process

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Spatial pattern events for Pde7a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pde7a	Mouse	Embryo	3F	34210887	3.24e-06
Pde7a	Mouse	Embryo	rep_13	33188776	3.01e-10
Pde7a	Mouse	Kidney	CLP	34003797	3.53e-06
Pde7a	Mouse	Intestine	rep_1	35149721	6.08e-15
Pde7a	Mouse	Intestine	rep_2	35149721	3.44e-15
Pde7a	Mouse	Intestine	rep_3	35149721	2.17e-08
Pde7a	Mouse	Lymph	B1	0	1.26e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E

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Spatial pattern pathway has Pde7a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Spinal cord	L7bCN01_D2	5.8e-07
Pde7a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Spinal cord	L7bCN01_D2	9.2e-06
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Spinal cord	L7bCN02_E1	7.8e-06
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN34_C1	7.9e-06
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	3.7e-06
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Pde7a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Pde7a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-07
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Pde7a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.1e-07
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Pde7a	GOBP_Camp_Metabolic_Process	Mouse	Spinal cord	L7CN45_E1	2.8e-06
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Spinal cord	L7CN97_E2	2.0e-07
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_42	5.1e-05
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Brain	rep_75	5.0e-06
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_75	8.0e-05
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_1	1.1e-31
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Brain	rep_1	7.9e-08
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Brain	rep_1	1.1e-10
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_1	5.1e-20
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Brain	rep_3	3.4e-221
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	rep_3	2.3e-101
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.9e-170
Pde7a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	rep_3	4.1e-202
Pde7a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	rep_3	1.2e-230
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	rep_3	6.2e-102
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Embryo	rep_14	2.7e-65
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Embryo	rep_14	1.0e-48
Pde7a	GOBP_Camp_Metabolic_Process	Mouse	Embryo	rep_14	7.0e-38
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Embryo	rep_14	1.7e-43
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Embryo	rep_14	3.7e-39
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Embryo	rep_14	1.3e-22
Pde7a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-64
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-21
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Pde7a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-44
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Embryo	rep_14	2.9e-51
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Embryo	rep_14	5.4e-32
Pde7a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	6.5e-20
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Embryo	rep_14	1.0e-59
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Pde7a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Embryo	rep_2	3.3e-45
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Kidney	rep_2	2.3e-09
Pde7a	GOBP_Camp_Metabolic_Process	Mouse	Kidney	rep_2	6.1e-12
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Kidney	rep_2	5.9e-48
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Kidney	rep_2	4.1e-29
Pde7a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Kidney	rep_2	2.6e-12
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	2.0e-16
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Kidney	rep_2	3.9e-15
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Pde7a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-17
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Kidney	rep_2	2.7e-12
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Kidney	rep_3	1.5e-04
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Liver	CN16-D1	1.1e-10
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Liver	CN16-D1	6.9e-14
Pde7a	GOBP_Camp_Metabolic_Process	Mouse	Liver	CN16-D2	6.1e-08
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	CN16-E1	4.0e-10
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Liver	CN65-C1	5.9e-10
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Liver	CN65-C1	4.9e-08
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Pde7a	GOBP_Camp_Metabolic_Process	Mouse	Liver	rep_15	8.0e-08
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Liver	rep_15	9.6e-10
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	rep_16	4.7e-11
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Liver	rep_16	5.2e-08
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Liver	rep_23	1.7e-25
Pde7a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Liver	rep_23	1.1e-07
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Lymph	MS-1	3.2e-10
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Lymph	MS-1	6.0e-17
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Pde7a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-11
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Pde7a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-12
Pde7a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.4e-09
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Lymph	MS-1	2.9e-12
Pde7a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	8.0e-08
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Lymph	MS-1	2.7e-14
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Lymph	MS-1	1.1e-10
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Lymph	MS-2	4.6e-08
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Lung	rep_1	1.7e-11
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Brain	rep_4	2.0e-24
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_4	9.1e-14
Pde7a	GOBP_Camp_Mediated_Signaling	Mouse	Brain	HP_ad_rep7	2.2e-12
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.8e-13
Pde7a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Pde7a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.5e-07
Pde7a	GOBP_Camp_Catabolic_Process	Mouse	Brain	HP_polb_rep1	3.8e-19
Pde7a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Brain	HP_polb_rep9	4.0e-16
Pde7a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Pde7a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	HP_polb_rep9	6.5e-09
Pde7a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16
Pde7a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Pde7a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-19
Pde7a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-08
Pde7a	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.2e-08
Pde7a	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Pde7a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.4e-07
Pde7a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Brain	HP_polb_rep9	2.7e-21
Pde7a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Pde7a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09
Pde7a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	HP_wt_rep2	2.8e-08

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Pde7a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pde7a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pde7a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pde7a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pde7a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source