|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Cdk18 (spascer ID:18557) |
Gene summary for Cdk18 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Cdk18 | Gene ID | 18557 |
| Gene name | cyclin-dependent kinase 18 |
| Synonyms | AA682070|Ctk18|Pctk3 |
| Cytomap | 1|1 E4 |
| Type of gene | protein-coding |
| Description | cyclin-dependent kinase 18PCTAIRE-motif protein kinase 3cell division protein kinase 18serine/threonine-protein kinase PCTAIRE-3 |
| Modification date | 20220424 |
| UniProtAcc | Q04899 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Cdk18 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 21873635 | Process |
| Cdk18 | GO:0005634 | nucleus | 21873635 | Component |
| Cdk18 | GO:0005737 | cytoplasm | 21873635 | Component |
| Cdk18 | GO:0006468 | protein phosphorylation | 21873635 | Process |
Top |
Spatial pattern events for Cdk18 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Cdk18 | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Cdk18 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Cdk18 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Cdk18 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Cdk18 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Cdk18 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Cdk18 | Mouse | Brain | 12B | 32637622 | 5.30e-07 |
| Cdk18 | Mouse | Brain | 19A | 32637622 | 3.78e-06 |
| Cdk18 | Mouse | Brain | 22A | 32637622 | 9.17e-06 |
| Cdk18 | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Cdk18 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Cdk18 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Cdk18 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Cdk18 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Cdk18 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Cdk18 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Cdk18 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Cdk18 | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Cdk18 | Mouse | Kidney | rep_3 | 34853151 | 2.08e-08 |
| Cdk18 | Mouse | Kidney | rep_5 | 34853151 | 3.44e-07 |
| Cdk18 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Cdk18 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Cdk18 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Cdk18 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Cdk18 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Cdk18 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Cdk18 | Mouse | Intestine | rep_1 | 35149721 | 1.10e-06 |
| Cdk18 | Mouse | Intestine | rep_3 | 35149721 | 4.56e-06 |
| Cdk18 | Mouse | Intestine | rep_4 | 35149721 | 1.12e-11 |
| Cdk18 | Mouse | Brain | B02_D1 | 32702314 | 4.59e-14 |
| Cdk18 | Mouse | Brain | B02_E1 | 32702314 | 4.15e-14 |
| Cdk18 | Mouse | Brain | B03_C2 | 32702314 | 2.93e-06 |
| Cdk18 | Mouse | Brain | B03_D2 | 32702314 | 4.50e-10 |
| Cdk18 | Mouse | Brain | N03_D2 | 32702314 | 1.67e-07 |
| Cdk18 | Mouse | Brain | N05_D2 | 32702314 | 1.13e-07 |
| Cdk18 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Cdk18 | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Cdk18 | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Cdk18 | Mouse | Brain | rep_7 | 35210624 | 1.64e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B02_D1_H&E  |  |
Brain_B02_E1_H&E  |  |
Brain_B03_C2_H&E  |  |
Brain_B03_D2_H&E  |  |
Brain_N03_D2_H&E  |  |
Brain_N05_D2_H&E  |  |
Top |
Spatial pattern pathway has Cdk18 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 1.1e-06 |
| Cdk18 | GOBP_Cell_Cycle_Process | Mouse | Spinal cord | CN94_E1 | 3.8e-06 |
| Cdk18 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Spinal cord | L7bCN02_E1 | 1.5e-06 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Spinal cord | L7CN45_C1 | 6.7e-08 |
| Cdk18 | GOBP_Mitotic_Cell_Cycle | Mouse | Spinal cord | L7CN45_C1 | 2.4e-08 |
| Cdk18 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Spinal cord | L7CN45_C1 | 3.0e-07 |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Brain | rep_27 | 8.4e-07 |
| Cdk18 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | rep_27 | 1.1e-05 |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Brain | rep_1 | 7.0e-10 |
| Cdk18 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Brain | rep_1 | 1.6e-31 |
| Cdk18 | GOBP_Cell_Cycle_Process | Mouse | Brain | rep_1 | 6.7e-14 |
| Cdk18 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | rep_1 | 1.5e-25 |
| Cdk18 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | rep_1 | 3.9e-14 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Brain | rep_1 | 3.3e-79 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Brain | rep_3 | 3.0e-140 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Embryo | rep_6 | 3.8e-08 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Embryo | rep_4 | 1.2e-08 |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Kidney | rep_2 | 1.0e-24 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Kidney | rep_2 | 5.1e-80 |
| Cdk18 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Kidney | rep_2 | 6.8e-67 |
| Cdk18 | GOBP_Cell_Cycle_Process | Mouse | Kidney | rep_2 | 3.0e-21 |
| Cdk18 | GOBP_Mitotic_Cell_Cycle | Mouse | Kidney | rep_2 | 1.1e-15 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Kidney | rep_2 | 1.3e-55 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Liver | CN16-D2 | 8.1e-07 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Liver | rep_16 | 1.3e-19 |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Lymph | MS-1 | 1.3e-07 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Lymph | MS-1 | 3.2e-07 |
| Cdk18 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Lymph | MS-1 | 6.4e-09 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Brain | rep_4 | 1.2e-51 |
| Cdk18 | GOBP_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 6.6e-08 |
| Cdk18 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Brain | HP_ad_rep7 | 3.5e-11 |
| Cdk18 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Brain | HP_ad_rep7 | 4.9e-09 |
| Cdk18 | GOBP_Cell_Cycle_Process | Mouse | Brain | HP_ad_rep7 | 1.7e-09 |
| Cdk18 | GOBP_Regulation_Of_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Cdk18 | GOBP_Regulation_Of_Transcription_Involved_In_G1_S_Transition_Of_Mitotic_Cell_Cycle | Mouse | Brain | HP_adpolb_rep2 | 1.3e-07 |
| Cdk18 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | HP_polb_rep9 | 1.6e-10 |
Top |
Cdk18 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Cdk18 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Cdk18 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Cdk18 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Cdk18 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
