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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pcp4 (spascer ID:18546)

Gene summary for Pcp4

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pcp4
	Gene ID	18546
	Gene name	Purkinje cell protein 4
	Synonyms	P16Rimb19\|Pcp-4\|Pep19
	Cytomap	16 C4\|16 56.97 cM
	Type of gene	protein-coding
	Description	calmodulin regulator protein PCP4brain-specific antigen PCP-4brain-specific polypeptide PEP-19
	Modification date	20220508
	UniProtAcc	P63054

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pcp4	GO:0005509	calcium ion binding	21873635	Function
Pcp4	GO:0005516	calmodulin binding	21873635	Function
Pcp4	GO:0005737	cytoplasm	21873635	Component

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Spatial pattern events for Pcp4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pcp4	Mouse	Brain	S1	34413515	2.07e-15
Pcp4	Mouse	Brain	S2	34413515	1.56e-15
Pcp4	Mouse	Brain	S3	34413515	1.64e-15
Pcp4	Mouse	Brain	S4	34413515	1.37e-15
Pcp4	Mouse	Brain	S6	34413515	1.46e-15
Pcp4	Mouse	Brain	S7	34413515	1.55e-15
Pcp4	Mouse	Brain	01A	32637622	7.64e-11
Pcp4	Mouse	Brain	01B	32637622	9.29e-14
Pcp4	Mouse	Brain	02A	32637622	2.91e-13
Pcp4	Mouse	Brain	02B	32637622	5.67e-13
Pcp4	Mouse	Brain	03A	32637622	3.96e-13
Pcp4	Mouse	Brain	03B	32637622	2.70e-13
Pcp4	Mouse	Brain	04A	32637622	8.85e-14
Pcp4	Mouse	Brain	04B	32637622	5.48e-14
Pcp4	Mouse	Brain	05A	32637622	3.09e-14
Pcp4	Mouse	Brain	05B	32637622	2.80e-14
Pcp4	Mouse	Brain	06A	32637622	2.52e-14
Pcp4	Mouse	Brain	06B	32637622	1.68e-14
Pcp4	Mouse	Brain	07A	32637622	1.93e-14
Pcp4	Mouse	Brain	07B	32637622	1.82e-14
Pcp4	Mouse	Brain	08A	32637622	2.39e-14
Pcp4	Mouse	Brain	08B	32637622	3.79e-14
Pcp4	Mouse	Brain	09A	32637622	2.68e-14
Pcp4	Mouse	Brain	09B	32637622	1.89e-14
Pcp4	Mouse	Brain	10A	32637622	3.84e-14
Pcp4	Mouse	Brain	10B	32637622	3.63e-14
Pcp4	Mouse	Brain	11A	32637622	1.61e-14
Pcp4	Mouse	Brain	12A	32637622	2.09e-14
Pcp4	Mouse	Brain	12B	32637622	1.20e-14
Pcp4	Mouse	Brain	13A	32637622	3.02e-14
Pcp4	Mouse	Brain	13B	32637622	1.72e-14
Pcp4	Mouse	Brain	14A	32637622	1.38e-14
Pcp4	Mouse	Brain	14B	32637622	1.35e-14
Pcp4	Mouse	Brain	15A	32637622	2.43e-14
Pcp4	Mouse	Brain	15B	32637622	2.07e-14
Pcp4	Mouse	Brain	16A	32637622	1.75e-14
Pcp4	Mouse	Brain	16B	32637622	2.21e-14
Pcp4	Mouse	Brain	17A	32637622	1.19e-14
Pcp4	Mouse	Brain	17B	32637622	1.32e-14
Pcp4	Mouse	Brain	18A	32637622	1.20e-14
Pcp4	Mouse	Brain	18B	32637622	1.38e-14
Pcp4	Mouse	Brain	19A	32637622	1.35e-14
Pcp4	Mouse	Brain	19B	32637622	1.36e-14
Pcp4	Mouse	Brain	20A	32637622	1.49e-14
Pcp4	Mouse	Brain	20B	32637622	1.86e-14
Pcp4	Mouse	Brain	21A	32637622	1.43e-14
Pcp4	Mouse	Brain	21B	32637622	1.37e-14
Pcp4	Mouse	Brain	22A	32637622	8.87e-15
Pcp4	Mouse	Brain	22B	32637622	8.81e-15
Pcp4	Mouse	Brain	23A	32637622	1.72e-14
Pcp4	Mouse	Brain	23B	32637622	1.10e-14
Pcp4	Mouse	Brain	24A	32637622	1.61e-14
Pcp4	Mouse	Brain	24B	32637622	1.40e-14
Pcp4	Mouse	Brain	25A	32637622	1.86e-14
Pcp4	Mouse	Brain	26A	32637622	1.34e-14
Pcp4	Mouse	Brain	26B	32637622	2.02e-14
Pcp4	Mouse	Brain	27A	32637622	1.74e-14
Pcp4	Mouse	Brain	27B	32637622	1.06e-14
Pcp4	Mouse	Brain	28A	32637622	1.06e-14
Pcp4	Mouse	Brain	28B	32637622	1.24e-14
Pcp4	Mouse	Brain	29A	32637622	1.82e-14
Pcp4	Mouse	Brain	29B	32637622	1.91e-14
Pcp4	Mouse	Brain	30A	32637622	2.66e-14
Pcp4	Mouse	Brain	31A	32637622	2.61e-14
Pcp4	Mouse	Brain	32A	32637622	3.18e-13
Pcp4	Mouse	Brain	33A	32637622	2.59e-14
Pcp4	Mouse	Brain	33B	32637622	1.17e-09
Pcp4	Mouse	Brain	34A	32637622	4.61e-14
Pcp4	Mouse	Brain	34B	32637622	5.74e-14
Pcp4	Mouse	Brain	35A	32637622	2.23e-10
Pcp4	Mouse	Brain	35B	32637622	7.88e-10
Pcp4	Mouse	Brain	36A	32637622	7.40e-14
Pcp4	Mouse	Brain	36B	32637622	1.95e-08
Pcp4	Mouse	Brain	37B	32637622	3.70e-12
Pcp4	Mouse	Brain	38A	32637622	4.24e-13
Pcp4	Mouse	Brain	38B	32637622	6.59e-14
Pcp4	Mouse	Brain	39A	32637622	5.97e-10
Pcp4	Mouse	Brain	39B	32637622	1.33e-07
Pcp4	Mouse	Brain	rep_1	35141374	2.02e-15
Pcp4	Mouse	Brain	rep_2	35141374	1.69e-15
Pcp4	Mouse	Brain	rep_3	35141374	1.64e-15
Pcp4	Mouse	Brain	rep_4	35141374	1.57e-15
Pcp4	Mouse	Brain	rep_5	35141374	1.47e-15
Pcp4	Mouse	Brain	rep_6	35141374	1.73e-15
Pcp4	Mouse	Kidney	rep_1	33976190	4.65e-10
Pcp4	Mouse	Brain	rep_1	33469025	1.30e-15
Pcp4	Mouse	Brain	rep_1	35027729	1.66e-15
Pcp4	Mouse	Brain	rep_2	35027729	1.57e-15
Pcp4	Mouse	Brain	rep_3	35027729	1.32e-15
Pcp4	Mouse	Brain	rep_4	35027729	1.76e-15
Pcp4	Mouse	Brain	rep_5	35027729	1.46e-15
Pcp4	Mouse	Intestine	rep_1	35149721	6.08e-15
Pcp4	Mouse	Intestine	rep_2	35149721	3.44e-15
Pcp4	Mouse	Brain	B02_D1	32702314	1.50e-14
Pcp4	Mouse	Brain	B02_E1	32702314	1.33e-14
Pcp4	Mouse	Brain	B03_C2	32702314	5.51e-14
Pcp4	Mouse	Brain	B03_D2	32702314	2.13e-14
Pcp4	Mouse	Brain	B04_D1	32702314	4.28e-14
Pcp4	Mouse	Brain	B04_E1	32702314	2.28e-14
Pcp4	Mouse	Brain	B05_D2	32702314	2.54e-14
Pcp4	Mouse	Brain	B05_E2	32702314	2.42e-14
Pcp4	Mouse	Brain	B06_E1	32702314	4.32e-14
Pcp4	Mouse	Brain	B07_C2	32702314	5.25e-14
Pcp4	Mouse	Brain	N02_C1	32702314	3.13e-14
Pcp4	Mouse	Brain	N02_D1	32702314	2.44e-14
Pcp4	Mouse	Brain	N03_C2	32702314	2.55e-14
Pcp4	Mouse	Brain	N03_D2	32702314	1.38e-14
Pcp4	Mouse	Brain	N04_D1	32702314	3.34e-14
Pcp4	Mouse	Brain	N04_E1	32702314	6.19e-14
Pcp4	Mouse	Brain	N05_C2	32702314	3.61e-14
Pcp4	Mouse	Brain	N05_D2	32702314	1.93e-14
Pcp4	Mouse	Brain	N06_D2	32702314	7.63e-14
Pcp4	Mouse	Brain	N07_C1	32702314	6.11e-14
Pcp4	Mouse	Brain	rep_1	35210624	1.74e-15
Pcp4	Mouse	Brain	rep_2	35210624	1.74e-15
Pcp4	Mouse	Brain	rep_3	35210624	1.82e-15
Pcp4	Mouse	Brain	rep_4	35210624	2.34e-15
Pcp4	Mouse	Brain	rep_5	35210624	2.07e-15
Pcp4	Mouse	Brain	rep_6	35210624	2.05e-15
Pcp4	Mouse	Brain	rep_7	35210624	1.87e-15
Pcp4	Mouse	Brain	OFB_ad_rep1	33083725	7.01e-09
Pcp4	Mouse	Brain	OFB_ad_rep2	33083725	7.25e-11
Pcp4	Mouse	Brain	OFB_ad_rep3	33083725	1.76e-12
Pcp4	Mouse	Brain	OFB_ad_rep4	33083725	6.01e-13
Pcp4	Mouse	Brain	OFB_ad_rep5	33083725	1.12e-12
Pcp4	Mouse	Brain	OFB_ad_rep6	33083725	1.74e-12
Pcp4	Mouse	Brain	OFB_adpolb_rep1	33083725	2.39e-09
Pcp4	Mouse	Brain	OFB_adpolb_rep2	33083725	1.25e-12
Pcp4	Mouse	Brain	OFB_adpolb_rep3	33083725	6.52e-13
Pcp4	Mouse	Brain	OFB_adpolb_rep4	33083725	4.74e-13
Pcp4	Mouse	Brain	OFB_adpolb_rep5	33083725	1.94e-12
Pcp4	Mouse	Brain	OFB_adpolb_rep6	33083725	1.84e-12
Pcp4	Mouse	Brain	OFB_polb_rep1	33083725	6.78e-05
Pcp4	Mouse	Brain	OFB_polb_rep5	33083725	2.26e-12
Pcp4	Mouse	Brain	OFB_polb_rep6	33083725	1.13e-11
Pcp4	Mouse	Brain	OFB_polb_rep7	33083725	1.83e-12
Pcp4	Mouse	Brain	OFB_polb_rep8	33083725	5.98e-12
Pcp4	Mouse	Brain	OFB_wt_rep1	33083725	2.11e-11
Pcp4	Mouse	Brain	OFB_wt_rep2	33083725	2.67e-12
Pcp4	Mouse	Brain	OFB_wt_rep3	33083725	4.42e-12
Pcp4	Mouse	Brain	OFB_wt_rep4	33083725	2.28e-11
Pcp4	Mouse	Brain	OFB_wt_rep5	33083725	5.23e-13
Pcp4	Mouse	Brain	OFB_wt_rep6	33083725	5.34e-13

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_D1_H&E
Brain_B04_E1_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Brain_B06_E1_H&E
Brain_B07_C2_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Brain_N06_D2_H&E
Brain_N07_C1_H&E
Brain_OFB_ad_rep1_H&E
Brain_OFB_ad_rep2_H&E
Brain_OFB_ad_rep3_H&E
Brain_OFB_ad_rep4_H&E
Brain_OFB_ad_rep5_H&E
Brain_OFB_ad_rep6_H&E
Brain_OFB_adpolb_rep1_H&E
Brain_OFB_adpolb_rep2_H&E
Brain_OFB_adpolb_rep3_H&E
Brain_OFB_adpolb_rep4_H&E
Brain_OFB_adpolb_rep5_H&E
Brain_OFB_adpolb_rep6_H&E
Brain_OFB_polb_rep1_H&E
Brain_OFB_polb_rep5_H&E
Brain_OFB_polb_rep6_H&E
Brain_OFB_polb_rep7_H&E
Brain_OFB_polb_rep8_H&E
Brain_OFB_wt_rep1_H&E
Brain_OFB_wt_rep2_H&E
Brain_OFB_wt_rep3_H&E
Brain_OFB_wt_rep4_H&E
Brain_OFB_wt_rep5_H&E
Brain_OFB_wt_rep6_H&E

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Spatial pattern pathway has Pcp4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	CN94_E1	3.3e-06
Pcp4	GOBP_Positive_Regulation_Of_Neuron_Differentiation	Mouse	Spinal cord	CN94_E1	5.1e-07
Pcp4	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Spinal cord	CN94_E1	1.1e-06
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	5.1e-06
Pcp4	GOBP_Neurogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Pcp4	GOBP_Neuron_Differentiation	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Spinal cord	L8CN11_C1	7.5e-11
Pcp4	GOBP_Neurogenesis	Mouse	Brain	rep_1	6.4e-19
Pcp4	GOBP_Neuron_Differentiation	Mouse	Brain	rep_1	8.7e-25
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_1	3.9e-15
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_1	2.3e-15
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Brain	rep_3	9.3e-50
Pcp4	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Brain	rep_5	1.2e-19
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Embryo	rep_14	1.1e-19
Pcp4	GOBP_Neurogenesis	Mouse	Embryo	rep_1	8.2e-08
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Embryo	rep_1	5.0e-13
Pcp4	GOBP_Neuron_Differentiation	Mouse	Embryo	rep_3	2.1e-193
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_3	6.3e-72
Pcp4	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Embryo	rep_3	1.5e-07
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_5	5.2e-15
Pcp4	GOBP_Neurogenesis	Mouse	Kidney	Nep	4.6e-22
Pcp4	GOBP_Neuron_Differentiation	Mouse	Kidney	Nep	8.3e-23
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Kidney	Nep	5.6e-37
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Kidney	rep_2	7.0e-36
Pcp4	GOBP_Neurogenesis	Mouse	Kidney	rep_2	2.4e-78
Pcp4	GOBP_Neuron_Differentiation	Mouse	Kidney	rep_2	3.9e-32
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Kidney	rep_2	3.1e-09
Pcp4	GOBP_Positive_Regulation_Of_Neuron_Differentiation	Mouse	Kidney	rep_2	6.9e-34
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Kidney	rep_2	2.6e-14
Pcp4	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Kidney	rep_2	5.7e-54
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Kidney	rep_3	1.4e-06
Pcp4	GOBP_Neuron_Differentiation	Mouse	Liver	CN16-D2	5.1e-07
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Liver	rep_15	5.7e-16
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Liver	rep_16	4.7e-08
Pcp4	GOBP_Positive_Regulation_Of_Neuron_Differentiation	Mouse	Liver	rep_16	1.2e-09
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Liver	rep_16	3.6e-08
Pcp4	GOBP_Calmodulin_Dependent_Kinase_Signaling_Pathway	Mouse	Intestine	rep_2	3.9e-77
Pcp4	GOBP_Neurogenesis	Mouse	Lymph	MS-1	4.1e-08
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	2.3e-12
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Lymph	MS-1	8.9e-15
Pcp4	GOBP_Positive_Regulation_Of_Neuron_Differentiation	Mouse	Lymph	MS-1	6.6e-11
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	1.3e-14
Pcp4	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Lymph	MS-1	1.2e-08
Pcp4	GOBP_Neurogenesis	Mouse	Brain	HP_ad_rep7	3.9e-07
Pcp4	GOBP_Neuron_Differentiation	Mouse	Brain	HP_ad_rep7	3.9e-07
Pcp4	GOBP_Positive_Regulation_Of_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	3.3e-07
Pcp4	GOBP_Positive_Regulation_Of_Developmental_Process	Mouse	Brain	HP_ad_rep7	4.0e-07
Pcp4	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	HP_polb_rep9	6.5e-09

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Pcp4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pcp4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pcp4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pcp4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pcp4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source