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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Pafah1b3 (spascer ID:18476)

Gene summary for Pafah1b3

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Pafah1b3

Gene ID

18476

Gene nameplatelet-activating factor acetylhydrolase, isoform 1b, subunit 3
SynonymsPafahg|mus[g]
Cytomap7|7 A3
Type of geneprotein-coding
Descriptionplatelet-activating factor acetylhydrolase IB subunit alpha1platelet-activating factor acetylhydrolase IB subunit gammaPAF acetylhydrolase 29 kDa subunitPAF-AH 29 kDa subunitPAF-AH gammaPAF-AH subunit gammaPAFAH subunit gamma
Modification date20220424
UniProtAcc

Q61205


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Pafah1b3

GO:0005737

cytoplasm

21873635

Component
Pafah1b3

GO:0007420

brain development

21873635

Process
Pafah1b3

GO:0047179

platelet-activating factor acetyltransferase activity

21873635

Function

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Spatial pattern events for Pafah1b3

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Pafah1b3MouseBrainS1 344135152.07e-15
Pafah1b3MouseBrainS2 344135151.56e-15
Pafah1b3MouseBrainS3 344135151.64e-15
Pafah1b3MouseBrainS4 344135151.37e-15
Pafah1b3MouseBrainS6 344135151.46e-15
Pafah1b3MouseBrainS7 344135151.55e-15
Pafah1b3MouseBrain24A 326376223.40e-06
Pafah1b3MouseBrainrep_1 351413742.02e-15
Pafah1b3MouseBrainrep_2 351413741.69e-15
Pafah1b3MouseBrainrep_3 351413741.64e-15
Pafah1b3MouseBrainrep_4 351413741.57e-15
Pafah1b3MouseBrainrep_5 351413741.47e-15
Pafah1b3MouseBrainrep_6 351413741.73e-15
Pafah1b3MouseEmbryo2H 342108871.33e-08
Pafah1b3MouseEmbryo4D 342108871.14e-12
Pafah1b3MouseEmbryorep_2 331887765.34e-08
Pafah1b3MouseEmbryorep_4 331887765.08e-15
Pafah1b3MouseKidneyCLP 340037972.19e-15
Pafah1b3MouseKidneySham 340037972.58e-15
Pafah1b3MouseKidneyrep_1 348531512.42e-15
Pafah1b3MouseBrainrep_1 334690251.30e-15
Pafah1b3MouseBrainrep_1 350277291.66e-15
Pafah1b3MouseBrainrep_2 350277291.57e-15
Pafah1b3MouseBrainrep_3 350277291.32e-15
Pafah1b3MouseBrainrep_4 350277291.76e-15
Pafah1b3MouseBrainrep_5 350277291.46e-15
Pafah1b3MouseIntestinerep_2 351497217.56e-12
Pafah1b3MouseIntestinerep_3 351497211.44e-06
Pafah1b3MouseIntestinerep_4 351497217.23e-15
Pafah1b3MouseBrainB02_D1 327023142.12e-07
Pafah1b3MouseBrainB02_E1 327023143.12e-07
Pafah1b3MouseBrainN05_D2 327023143.56e-08
Pafah1b3MouseLymphA1 01.01e-07
Pafah1b3MouseLymphB1 01.28e-07
Pafah1b3MouseLungrep_1 352908016.56e-15
Pafah1b3MouseLungrep_2 352908019.51e-14
Pafah1b3MouseLungrep_3 352908015.26e-15
Pafah1b3MouseLungrep_4 352908011.02e-14
Pafah1b3MouseBrainrep_1 352106241.74e-15
Pafah1b3MouseBrainrep_2 352106241.74e-15
Pafah1b3MouseBrainrep_3 352106241.82e-15
Pafah1b3MouseBrainrep_7 352106241.87e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_D1_H&E
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Brain_B02_E1_H&E
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Brain_N05_D2_H&E
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Lung_rep_1_H&E
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Lung_rep_2_H&E
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Lung_rep_3_H&E
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Lung_rep_4_H&E
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Spatial pattern pathway has Pafah1b3 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Pafah1b3GOBP_Developmental_Process_Involved_In_ReproductionMouseSpinal cordCN94_E1 3.2e-07
Pafah1b3GOBP_Gamete_GenerationMouseSpinal cordCN94_E1 3.1e-07
Pafah1b3GOBP_Male_Gamete_GenerationMouseSpinal cordCN94_E1 4.7e-06
Pafah1b3GOBP_ReproductionMouseSpinal cordCN94_E1 7.8e-08
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseSpinal cordL7bCN02_E1 8.9e-07
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseSpinal cordL7CN45_C1 5.5e-10
Pafah1b3GOBP_Head_DevelopmentMouseSpinal cordL7CN45_C1 3.4e-09
Pafah1b3GOBP_Lipid_Catabolic_ProcessMouseSpinal cordL7CN45_C1 8.5e-07
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseSpinal cordL7CN45_C1 7.1e-07
Pafah1b3GOBP_Gamete_GenerationMouseBrainrep_27 5.2e-05
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseBrainrep_1 8.6e-30
Pafah1b3GOBP_Head_DevelopmentMouseBrainrep_1 3.9e-29
Pafah1b3GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainrep_32.9e-159
Pafah1b3GOBP_Gamete_GenerationMouseBrainrep_31.3e-194
Pafah1b3GOBP_Lipid_Catabolic_ProcessMouseBrainrep_31.4e-121
Pafah1b3GOBP_Male_Gamete_GenerationMouseBrainrep_31.6e-190
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseBrainrep_3 1.2e-58
Pafah1b3GOBP_ReproductionMouseBrainrep_33.4e-125
Pafah1b3GOBP_Gamete_GenerationMouseEmbryorep_14 6.5e-07
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_14 5.9e-07
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseEmbryorep_13.0e-261
Pafah1b3GOBP_Head_DevelopmentMouseEmbryorep_1 1.8e-91
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseEmbryorep_1 2.1e-39
Pafah1b3GOBP_Male_Gamete_GenerationMouseEmbryorep_1 0.0e+00
Pafah1b3GOBP_Gamete_GenerationMouseEmbryorep_32.1e-220
Pafah1b3GOBP_Lipid_Catabolic_ProcessMouseEmbryorep_3 2.1e-07
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_38.7e-222
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseKidneyNep 4.2e-26
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseKidneyNep 4.2e-26
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseKidneyrep_2 1.3e-23
Pafah1b3GOBP_Developmental_Process_Involved_In_ReproductionMouseKidneyrep_2 3.6e-46
Pafah1b3GOBP_Gamete_GenerationMouseKidneyrep_2 5.0e-33
Pafah1b3GOBP_Head_DevelopmentMouseKidneyrep_2 1.9e-29
Pafah1b3GOBP_Lipid_Catabolic_ProcessMouseKidneyrep_2 1.4e-56
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseKidneyrep_2 1.4e-78
Pafah1b3GOBP_Male_Gamete_GenerationMouseKidneyrep_2 5.8e-51
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseKidneyrep_2 1.6e-53
Pafah1b3GOBP_ReproductionMouseKidneyrep_2 9.0e-46
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseLiverrep_16 8.2e-15
Pafah1b3GOBP_Head_DevelopmentMouseLiverrep_16 4.3e-18
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseLymphMS-1 3.8e-07
Pafah1b3GOBP_Developmental_Process_Involved_In_ReproductionMouseLymphMS-1 2.2e-10
Pafah1b3GOBP_Gamete_GenerationMouseLymphMS-1 7.7e-08
Pafah1b3GOBP_Lipid_Catabolic_ProcessMouseLymphMS-1 2.6e-07
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseLymphMS-1 9.7e-11
Pafah1b3GOBP_Male_Gamete_GenerationMouseLymphMS-1 1.6e-08
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseLymphMS-1 1.1e-09
Pafah1b3GOBP_ReproductionMouseLymphMS-1 1.1e-09
Pafah1b3GOBP_ReproductionMouseLungrep_1 9.6e-12
Pafah1b3GOBP_Central_Nervous_System_DevelopmentMouseBrainHP_ad_rep7 2.3e-07
Pafah1b3GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainHP_ad_rep7 2.5e-08
Pafah1b3GOBP_Gamete_GenerationMouseBrainHP_ad_rep7 1.3e-11
Pafah1b3GOBP_Head_DevelopmentMouseBrainHP_ad_rep7 3.0e-07
Pafah1b3GOBP_Multicellular_Organism_ReproductionMouseBrainHP_ad_rep7 6.1e-08
Pafah1b3GOBP_ReproductionMouseBrainHP_ad_rep7 7.9e-09
Pafah1b3GOBP_Male_Gamete_GenerationMouseBrainHP_ad_rep8 8.4e-07
Pafah1b3GOBP_Lipid_Metabolic_ProcessMouseBrainHP_polb_rep9 9.9e-11

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Pafah1b3 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Pafah1b3 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Pafah1b3 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Pafah1b3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Pafah1b3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource