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Spatial pattern gene: Pafah1b3 (spascer ID:18476) |
Gene summary for Pafah1b3 |
Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Pafah1b3 | Gene ID | 18476 |
| Gene name | platelet-activating factor acetylhydrolase, isoform 1b, subunit 3 |
| Synonyms | Pafahg|mus[g] |
| Cytomap | 7|7 A3 |
| Type of gene | protein-coding |
| Description | platelet-activating factor acetylhydrolase IB subunit alpha1platelet-activating factor acetylhydrolase IB subunit gammaPAF acetylhydrolase 29 kDa subunitPAF-AH 29 kDa subunitPAF-AH gammaPAF-AH subunit gammaPAFAH subunit gamma |
| Modification date | 20220424 |
| UniProtAcc | Q61205 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Pafah1b3 | GO:0005737 | cytoplasm | 21873635 | Component |
| Pafah1b3 | GO:0007420 | brain development | 21873635 | Process |
| Pafah1b3 | GO:0047179 | platelet-activating factor acetyltransferase activity | 21873635 | Function |
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Spatial pattern events for Pafah1b3 |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Pafah1b3 | Mouse | Brain | S1 | 34413515 | 2.07e-15 |
| Pafah1b3 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Pafah1b3 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Pafah1b3 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Pafah1b3 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Pafah1b3 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Pafah1b3 | Mouse | Brain | 24A | 32637622 | 3.40e-06 |
| Pafah1b3 | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Pafah1b3 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Pafah1b3 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Pafah1b3 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Pafah1b3 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Pafah1b3 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Pafah1b3 | Mouse | Embryo | 2H | 34210887 | 1.33e-08 |
| Pafah1b3 | Mouse | Embryo | 4D | 34210887 | 1.14e-12 |
| Pafah1b3 | Mouse | Embryo | rep_2 | 33188776 | 5.34e-08 |
| Pafah1b3 | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Pafah1b3 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Pafah1b3 | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Pafah1b3 | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Pafah1b3 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Pafah1b3 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Pafah1b3 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Pafah1b3 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Pafah1b3 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Pafah1b3 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Pafah1b3 | Mouse | Intestine | rep_2 | 35149721 | 7.56e-12 |
| Pafah1b3 | Mouse | Intestine | rep_3 | 35149721 | 1.44e-06 |
| Pafah1b3 | Mouse | Intestine | rep_4 | 35149721 | 7.23e-15 |
| Pafah1b3 | Mouse | Brain | B02_D1 | 32702314 | 2.12e-07 |
| Pafah1b3 | Mouse | Brain | B02_E1 | 32702314 | 3.12e-07 |
| Pafah1b3 | Mouse | Brain | N05_D2 | 32702314 | 3.56e-08 |
| Pafah1b3 | Mouse | Lymph | A1 | 0 | 1.01e-07 |
| Pafah1b3 | Mouse | Lymph | B1 | 0 | 1.28e-07 |
| Pafah1b3 | Mouse | Lung | rep_1 | 35290801 | 6.56e-15 |
| Pafah1b3 | Mouse | Lung | rep_2 | 35290801 | 9.51e-14 |
| Pafah1b3 | Mouse | Lung | rep_3 | 35290801 | 5.26e-15 |
| Pafah1b3 | Mouse | Lung | rep_4 | 35290801 | 1.02e-14 |
| Pafah1b3 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Pafah1b3 | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Pafah1b3 | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Pafah1b3 | Mouse | Brain | rep_7 | 35210624 | 1.87e-15 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has Pafah1b3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Pafah1b3 | GOBP_Developmental_Process_Involved_In_Reproduction | Mouse | Spinal cord | CN94_E1 | 3.2e-07 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Spinal cord | CN94_E1 | 3.1e-07 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Spinal cord | CN94_E1 | 4.7e-06 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Spinal cord | CN94_E1 | 7.8e-08 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Spinal cord | L7bCN02_E1 | 8.9e-07 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Spinal cord | L7CN45_C1 | 5.5e-10 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Pafah1b3 | GOBP_Lipid_Catabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 8.5e-07 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Spinal cord | L7CN45_C1 | 7.1e-07 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Brain | rep_27 | 5.2e-05 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Brain | rep_1 | 8.6e-30 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Brain | rep_1 | 3.9e-29 |
| Pafah1b3 | GOBP_Developmental_Process_Involved_In_Reproduction | Mouse | Brain | rep_3 | 2.9e-159 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Brain | rep_3 | 1.3e-194 |
| Pafah1b3 | GOBP_Lipid_Catabolic_Process | Mouse | Brain | rep_3 | 1.4e-121 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Brain | rep_3 | 1.6e-190 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Brain | rep_3 | 1.2e-58 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Brain | rep_3 | 3.4e-125 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Embryo | rep_14 | 6.5e-07 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Embryo | rep_14 | 5.9e-07 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Embryo | rep_1 | 3.0e-261 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Embryo | rep_1 | 1.8e-91 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Embryo | rep_1 | 2.1e-39 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Embryo | rep_1 | 0.0e+00 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Embryo | rep_3 | 2.1e-220 |
| Pafah1b3 | GOBP_Lipid_Catabolic_Process | Mouse | Embryo | rep_3 | 2.1e-07 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Embryo | rep_3 | 8.7e-222 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Kidney | Nep | 4.2e-26 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Kidney | Nep | 4.2e-26 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Kidney | rep_2 | 1.3e-23 |
| Pafah1b3 | GOBP_Developmental_Process_Involved_In_Reproduction | Mouse | Kidney | rep_2 | 3.6e-46 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Kidney | rep_2 | 5.0e-33 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Kidney | rep_2 | 1.9e-29 |
| Pafah1b3 | GOBP_Lipid_Catabolic_Process | Mouse | Kidney | rep_2 | 1.4e-56 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Kidney | rep_2 | 1.4e-78 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Kidney | rep_2 | 5.8e-51 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Kidney | rep_2 | 1.6e-53 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Kidney | rep_2 | 9.0e-46 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Liver | rep_16 | 8.2e-15 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Liver | rep_16 | 4.3e-18 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Lymph | MS-1 | 3.8e-07 |
| Pafah1b3 | GOBP_Developmental_Process_Involved_In_Reproduction | Mouse | Lymph | MS-1 | 2.2e-10 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Lymph | MS-1 | 7.7e-08 |
| Pafah1b3 | GOBP_Lipid_Catabolic_Process | Mouse | Lymph | MS-1 | 2.6e-07 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Lymph | MS-1 | 9.7e-11 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Lymph | MS-1 | 1.6e-08 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Lymph | MS-1 | 1.1e-09 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Lymph | MS-1 | 1.1e-09 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Lung | rep_1 | 9.6e-12 |
| Pafah1b3 | GOBP_Central_Nervous_System_Development | Mouse | Brain | HP_ad_rep7 | 2.3e-07 |
| Pafah1b3 | GOBP_Developmental_Process_Involved_In_Reproduction | Mouse | Brain | HP_ad_rep7 | 2.5e-08 |
| Pafah1b3 | GOBP_Gamete_Generation | Mouse | Brain | HP_ad_rep7 | 1.3e-11 |
| Pafah1b3 | GOBP_Head_Development | Mouse | Brain | HP_ad_rep7 | 3.0e-07 |
| Pafah1b3 | GOBP_Multicellular_Organism_Reproduction | Mouse | Brain | HP_ad_rep7 | 6.1e-08 |
| Pafah1b3 | GOBP_Reproduction | Mouse | Brain | HP_ad_rep7 | 7.9e-09 |
| Pafah1b3 | GOBP_Male_Gamete_Generation | Mouse | Brain | HP_ad_rep8 | 8.4e-07 |
| Pafah1b3 | GOBP_Lipid_Metabolic_Process | Mouse | Brain | HP_polb_rep9 | 9.9e-11 |
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Pafah1b3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Pafah1b3 function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Pafah1b3 envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for Pafah1b3 |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Pafah1b3 |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |