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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Pafah1b2 (spascer ID:18475)

Gene summary for Pafah1b2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Pafah1b2

Gene ID

18475

Gene nameplatelet-activating factor acetylhydrolase, isoform 1b, subunit 2
Synonyms2610005M20Rik|AI747451|AU021353|Pafahb|mus[b]
Cytomap9|9 A5.2
Type of geneprotein-coding
Descriptionplatelet-activating factor acetylhydrolase IB subunit alpha2platelet-activating factor acetylhydrolase IB subunit betaPAF acetylhydrolase 30 kDa subunitPAF-AH 30 kDa subunitPAF-AH subunit beta
Modification date20220424
UniProtAcc

Q61206


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Pafah1b2

GO:0005737

cytoplasm

21873635

Component
Pafah1b2

GO:0007420

brain development

21873635

Process
Pafah1b2

GO:0047179

platelet-activating factor acetyltransferase activity

21873635

Function

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Spatial pattern events for Pafah1b2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Pafah1b2MouseBrainS3 344135153.78e-11
Pafah1b2MouseBrainS4 344135152.43e-15
Pafah1b2MouseBrain24B 326376225.24e-08
Pafah1b2MouseBrain28A 326376225.38e-10
Pafah1b2MouseBrain29B 326376229.69e-06
Pafah1b2MouseBrainrep_1 351413741.28e-07
Pafah1b2MouseBrainrep_2 351413744.85e-07
Pafah1b2MouseBrainrep_3 351413742.07e-06
Pafah1b2MouseBrainrep_4 351413748.92e-14
Pafah1b2MouseBrainrep_5 351413741.47e-15
Pafah1b2MouseBrainrep_6 351413742.07e-11
Pafah1b2MouseEmbryorep_12 331887763.74e-06
Pafah1b2MouseEmbryorep_13 331887766.37e-08
Pafah1b2MouseKidneyrep_1 348531515.33e-07
Pafah1b2MouseBrainrep_1 334690251.30e-15
Pafah1b2MouseBrainrep_1 350277295.03e-10
Pafah1b2MouseBrainrep_2 350277292.23e-09
Pafah1b2MouseBrainrep_3 350277291.32e-15
Pafah1b2MouseBrainrep_5 350277296.34e-14
Pafah1b2MouseBrainB05_D2 327023145.90e-07
Pafah1b2MouseBrainN07_C1 327023142.20e-07
Pafah1b2MouseLungrep_1 352908017.42e-13
Pafah1b2MouseLungrep_3 352908013.01e-10
Pafah1b2MouseLungrep_4 352908012.22e-10

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_5_H&E
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Brain_B05_D2_H&E
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Brain_N07_C1_H&E
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Lung_rep_1_H&E
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Lung_rep_3_H&E
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Lung_rep_4_H&E
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Spatial pattern pathway has Pafah1b2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Pafah1b2GOBP_Developmental_Process_Involved_In_ReproductionMouseSpinal cordCN94_E1 3.2e-07
Pafah1b2GOBP_Gamete_GenerationMouseSpinal cordCN94_E1 3.1e-07
Pafah1b2GOBP_Male_Gamete_GenerationMouseSpinal cordCN94_E1 4.7e-06
Pafah1b2GOBP_ReproductionMouseSpinal cordCN94_E1 7.8e-08
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseSpinal cordL7bCN02_E1 8.9e-07
Pafah1b2GOBP_Cell_ActivationMouseSpinal cordL7CN45_C1 8.5e-07
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseSpinal cordL7CN45_C1 9.9e-07
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseSpinal cordL7CN45_C1 5.5e-10
Pafah1b2GOBP_Head_DevelopmentMouseSpinal cordL7CN45_C1 3.4e-09
Pafah1b2GOBP_Immune_Effector_ProcessMouseSpinal cordL7CN45_C1 3.1e-07
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 2.4e-06
Pafah1b2GOBP_Lipid_Catabolic_ProcessMouseSpinal cordL7CN45_C1 8.5e-07
Pafah1b2GOBP_MacroautophagyMouseSpinal cordL7CN45_C1 1.0e-06
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseSpinal cordL7CN45_C1 7.1e-07
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseSpinal cordL7CN45_C1 2.2e-07
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 6.7e-06
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseSpinal cordL7CN45_C1 3.1e-07
Pafah1b2GOBP_Positive_Regulation_Of_Catabolic_ProcessMouseSpinal cordL7CN45_C1 1.6e-07
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseSpinal cordL7CN45_C1 4.1e-06
Pafah1b2GOBP_Process_Utilizing_Autophagic_MechanismMouseSpinal cordL7CN45_C1 3.6e-07
Pafah1b2GOBP_Regulation_Of_AutophagyMouseSpinal cordL7CN45_C1 2.3e-07
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseSpinal cordL7CN45_C1 3.2e-07
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseSpinal cordL7CN45_C1 4.4e-06
Pafah1b2GOBP_SecretionMouseSpinal cordL7CN45_C1 8.1e-09
Pafah1b2GOBP_ExocytosisMouseSpinal cordL7CN47_C1 7.4e-07
Pafah1b2GOBP_Gamete_GenerationMouseBrainrep_27 5.2e-05
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_27 3.0e-05
Pafah1b2GOBP_SecretionMouseBrainrep_27 8.9e-05
Pafah1b2GOBP_Cell_ActivationMouseBrainrep_72 4.6e-06
Pafah1b2GOBP_Cell_ActivationMouseBrainrep_1 1.8e-07
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_1 2.6e-13
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseBrainrep_1 8.6e-30
Pafah1b2GOBP_ExocytosisMouseBrainrep_1 3.4e-73
Pafah1b2GOBP_Head_DevelopmentMouseBrainrep_1 3.9e-29
Pafah1b2GOBP_Immune_Effector_ProcessMouseBrainrep_1 1.5e-12
Pafah1b2GOBP_MacroautophagyMouseBrainrep_1 6.7e-14
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_1 2.1e-07
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_1 1.3e-13
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseBrainrep_1 1.3e-15
Pafah1b2GOBP_SecretionMouseBrainrep_1 4.1e-45
Pafah1b2GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainrep_32.9e-159
Pafah1b2GOBP_Gamete_GenerationMouseBrainrep_31.3e-194
Pafah1b2GOBP_Lipid_Catabolic_ProcessMouseBrainrep_31.4e-121
Pafah1b2GOBP_Male_Gamete_GenerationMouseBrainrep_31.6e-190
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseBrainrep_3 1.2e-58
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseBrainrep_32.8e-115
Pafah1b2GOBP_Positive_Regulation_Of_Catabolic_ProcessMouseBrainrep_31.3e-145
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseBrainrep_37.0e-106
Pafah1b2GOBP_Process_Utilizing_Autophagic_MechanismMouseBrainrep_31.0e-145
Pafah1b2GOBP_Regulation_Of_AutophagyMouseBrainrep_35.7e-133
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseBrainrep_31.9e-185
Pafah1b2GOBP_ReproductionMouseBrainrep_33.4e-125
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.3e-32
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_6 1.4e-16
Pafah1b2GOBP_Gamete_GenerationMouseEmbryorep_14 6.5e-07
Pafah1b2GOBP_Immune_Effector_ProcessMouseEmbryorep_14 3.3e-15
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 3.8e-12
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_14 5.9e-07
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseEmbryorep_14 2.9e-28
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 1.7e-32
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseEmbryorep_14 2.9e-10
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseEmbryorep_13.0e-261
Pafah1b2GOBP_Head_DevelopmentMouseEmbryorep_1 1.8e-91
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseEmbryorep_1 2.1e-39
Pafah1b2GOBP_Male_Gamete_GenerationMouseEmbryorep_1 0.0e+00
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_2 3.4e-34
Pafah1b2GOBP_Immune_Effector_ProcessMouseEmbryorep_2 1.7e-23
Pafah1b2GOBP_Gamete_GenerationMouseEmbryorep_32.1e-220
Pafah1b2GOBP_Lipid_Catabolic_ProcessMouseEmbryorep_3 2.1e-07
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseEmbryorep_38.7e-222
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseEmbryorep_3 1.8e-17
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseKidneyNep 4.2e-26
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseKidneyNep 4.2e-26
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyNep 4.2e-26
Pafah1b2GOBP_Cell_ActivationMouseKidneyrep_2 5.1e-83
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseKidneyrep_24.3e-101
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseKidneyrep_2 1.3e-23
Pafah1b2GOBP_Developmental_Process_Involved_In_ReproductionMouseKidneyrep_2 3.6e-46
Pafah1b2GOBP_ExocytosisMouseKidneyrep_23.2e-107
Pafah1b2GOBP_Gamete_GenerationMouseKidneyrep_2 5.0e-33
Pafah1b2GOBP_Head_DevelopmentMouseKidneyrep_2 1.9e-29
Pafah1b2GOBP_Immune_Effector_ProcessMouseKidneyrep_23.4e-107
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseKidneyrep_22.7e-133
Pafah1b2GOBP_Lipid_Catabolic_ProcessMouseKidneyrep_2 1.4e-56
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseKidneyrep_2 1.4e-78
Pafah1b2GOBP_MacroautophagyMouseKidneyrep_2 1.3e-64
Pafah1b2GOBP_Male_Gamete_GenerationMouseKidneyrep_2 5.8e-51
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseKidneyrep_2 1.6e-53
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseKidneyrep_22.2e-110
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyrep_26.6e-105
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseKidneyrep_2 2.9e-54
Pafah1b2GOBP_Positive_Regulation_Of_Catabolic_ProcessMouseKidneyrep_2 5.0e-13
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseKidneyrep_2 1.1e-44
Pafah1b2GOBP_Process_Utilizing_Autophagic_MechanismMouseKidneyrep_2 1.8e-66
Pafah1b2GOBP_Regulation_Of_AutophagyMouseKidneyrep_2 3.9e-60
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseKidneyrep_2 6.3e-37
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseKidneyrep_2 1.7e-73
Pafah1b2GOBP_ReproductionMouseKidneyrep_2 9.0e-46
Pafah1b2GOBP_SecretionMouseKidneyrep_2 1.6e-23
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseLiverrep_15 2.4e-09
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLiverrep_16 1.6e-18
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseLiverrep_16 8.2e-15
Pafah1b2GOBP_ExocytosisMouseLiverrep_16 8.5e-07
Pafah1b2GOBP_Head_DevelopmentMouseLiverrep_16 4.3e-18
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLiverrep_16 2.2e-20
Pafah1b2GOBP_Cell_ActivationMouseLymphMS-1 1.6e-18
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLymphMS-1 9.7e-16
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseLymphMS-1 3.8e-07
Pafah1b2GOBP_Developmental_Process_Involved_In_ReproductionMouseLymphMS-1 2.2e-10
Pafah1b2GOBP_ExocytosisMouseLymphMS-1 1.4e-14
Pafah1b2GOBP_Gamete_GenerationMouseLymphMS-1 7.7e-08
Pafah1b2GOBP_Immune_Effector_ProcessMouseLymphMS-1 1.6e-18
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseLymphMS-1 5.6e-21
Pafah1b2GOBP_Lipid_Catabolic_ProcessMouseLymphMS-1 2.6e-07
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseLymphMS-1 9.7e-11
Pafah1b2GOBP_MacroautophagyMouseLymphMS-1 3.3e-11
Pafah1b2GOBP_Male_Gamete_GenerationMouseLymphMS-1 1.6e-08
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseLymphMS-1 1.1e-09
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseLymphMS-1 1.0e-18
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLymphMS-1 6.6e-07
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseLymphMS-1 5.4e-09
Pafah1b2GOBP_Positive_Regulation_Of_Catabolic_ProcessMouseLymphMS-1 1.8e-09
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseLymphMS-1 2.0e-09
Pafah1b2GOBP_Process_Utilizing_Autophagic_MechanismMouseLymphMS-1 3.9e-13
Pafah1b2GOBP_Regulation_Of_AutophagyMouseLymphMS-1 1.1e-11
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseLymphMS-1 2.3e-12
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseLymphMS-1 9.8e-10
Pafah1b2GOBP_ReproductionMouseLymphMS-1 1.1e-09
Pafah1b2GOBP_SecretionMouseLymphMS-1 2.3e-12
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseLungrep_1 1.2e-11
Pafah1b2GOBP_ReproductionMouseLungrep_1 9.6e-12
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_4 2.9e-33
Pafah1b2GOBP_ExocytosisMouseBrainrep_4 2.4e-43
Pafah1b2GOBP_Immune_Effector_ProcessMouseBrainrep_4 7.2e-15
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 6.4e-19
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_4 3.5e-20
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.7e-62
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseBrainrep_4 4.5e-10
Pafah1b2GOBP_Central_Nervous_System_DevelopmentMouseBrainHP_ad_rep7 2.3e-07
Pafah1b2GOBP_Developmental_Process_Involved_In_ReproductionMouseBrainHP_ad_rep7 2.5e-08
Pafah1b2GOBP_Gamete_GenerationMouseBrainHP_ad_rep7 1.3e-11
Pafah1b2GOBP_Head_DevelopmentMouseBrainHP_ad_rep7 3.0e-07
Pafah1b2GOBP_MacroautophagyMouseBrainHP_ad_rep7 1.6e-07
Pafah1b2GOBP_Multicellular_Organism_ReproductionMouseBrainHP_ad_rep7 6.1e-08
Pafah1b2GOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainHP_ad_rep7 4.4e-14
Pafah1b2GOBP_Positive_Regulation_Of_AutophagyMouseBrainHP_ad_rep7 7.1e-08
Pafah1b2GOBP_Process_Utilizing_Autophagic_MechanismMouseBrainHP_ad_rep7 3.5e-08
Pafah1b2GOBP_Regulation_Of_Catabolic_ProcessMouseBrainHP_ad_rep7 3.3e-07
Pafah1b2GOBP_ReproductionMouseBrainHP_ad_rep7 7.9e-09
Pafah1b2GOBP_SecretionMouseBrainHP_ad_rep7 1.6e-08
Pafah1b2GOBP_Male_Gamete_GenerationMouseBrainHP_ad_rep8 8.4e-07
Pafah1b2GOBP_Cell_ActivationMouseBrainHP_polb_rep9 1.5e-08
Pafah1b2GOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainHP_polb_rep9 8.8e-09
Pafah1b2GOBP_ExocytosisMouseBrainHP_polb_rep9 2.3e-13
Pafah1b2GOBP_Immune_Effector_ProcessMouseBrainHP_polb_rep9 1.0e-08
Pafah1b2GOBP_Leukocyte_Mediated_ImmunityMouseBrainHP_polb_rep9 2.8e-07
Pafah1b2GOBP_Lipid_Metabolic_ProcessMouseBrainHP_polb_rep9 9.9e-11
Pafah1b2GOBP_Myeloid_Leukocyte_ActivationMouseBrainHP_polb_rep9 2.6e-11
Pafah1b2GOBP_Positive_Regulation_Of_Catabolic_ProcessMouseBrainHP_polb_rep9 3.3e-11
Pafah1b2GOBP_Positive_Regulation_Of_MacroautophagyMouseBrainHP_polb_rep9 4.0e-10
Pafah1b2GOBP_Regulation_Of_AutophagyMouseBrainHP_polb_rep9 5.5e-09
Pafah1b2GOBP_Regulation_Of_MacroautophagyMouseBrainHP_polb_rep9 3.3e-11

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Pafah1b2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Pafah1b2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Pafah1b2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Pafah1b2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Pafah1b2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource