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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mgp (spascer ID:17313)

Gene summary for Mgp

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mgp
	Gene ID	17313
	Gene name	matrix Gla protein
	Synonyms	Mglap
	Cytomap	6\|6 G1
	Type of gene	protein-coding
	Description	matrix Gla proteinmatrix gamma-carboxyglutamate (gla) protein
	Modification date	20220424
	UniProtAcc	P19788

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mgp	GO:0031012	extracellular matrix	21873635	Component

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Spatial pattern events for Mgp

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mgp	Mouse	Brain	S1	34413515	2.07e-15
Mgp	Mouse	Brain	S2	34413515	1.56e-15
Mgp	Mouse	Brain	S3	34413515	1.64e-15
Mgp	Mouse	Brain	S4	34413515	1.37e-15
Mgp	Mouse	Brain	S6	34413515	1.46e-15
Mgp	Mouse	Brain	S7	34413515	5.47e-15
Mgp	Mouse	Brain	29B	32637622	5.38e-08
Mgp	Mouse	Brain	32A	32637622	1.47e-09
Mgp	Mouse	Brain	36A	32637622	5.79e-11
Mgp	Mouse	Brain	36B	32637622	1.22e-08
Mgp	Mouse	Brain	rep_1	35141374	2.02e-15
Mgp	Mouse	Brain	rep_2	35141374	1.69e-15
Mgp	Mouse	Brain	rep_3	35141374	1.64e-15
Mgp	Mouse	Brain	rep_4	35141374	1.57e-15
Mgp	Mouse	Brain	rep_5	35141374	1.47e-15
Mgp	Mouse	Brain	rep_6	35141374	1.73e-15
Mgp	Mouse	Kidney	CLP	34003797	2.19e-15
Mgp	Mouse	Kidney	IRI	34003797	2.29e-15
Mgp	Mouse	Kidney	Sham	34003797	2.58e-15
Mgp	Mouse	Kidney	rep_1	34853151	2.42e-15
Mgp	Mouse	Kidney	rep_2	34853151	3.38e-15
Mgp	Mouse	Kidney	rep_3	34853151	2.94e-15
Mgp	Mouse	Kidney	rep_4	34853151	4.07e-15
Mgp	Mouse	Kidney	rep_5	34853151	3.18e-15
Mgp	Mouse	Brain	rep_1	33469025	1.30e-15
Mgp	Mouse	Liver	rep_14	35021063	2.99e-14
Mgp	Mouse	Liver	rep_18	35021063	8.00e-13
Mgp	Mouse	Liver	rep_20	35021063	9.91e-15
Mgp	Mouse	Liver	rep_21	35021063	8.03e-15
Mgp	Mouse	Liver	rep_22	35021063	1.07e-14
Mgp	Mouse	Brain	rep_1	35027729	1.66e-15
Mgp	Mouse	Brain	rep_2	35027729	1.57e-15
Mgp	Mouse	Brain	rep_3	35027729	1.32e-15
Mgp	Mouse	Brain	rep_4	35027729	1.76e-15
Mgp	Mouse	Brain	rep_5	35027729	1.46e-15
Mgp	Mouse	Intestine	rep_1	35149721	6.08e-15
Mgp	Mouse	Intestine	rep_2	35149721	3.44e-15
Mgp	Mouse	Intestine	rep_3	35149721	3.25e-15
Mgp	Mouse	Intestine	rep_4	35149721	2.30e-15
Mgp	Mouse	Lymph	A1	0	3.29e-15
Mgp	Mouse	Lymph	B1	0	3.66e-15
Mgp	Mouse	Lung	rep_1	35290801	4.52e-15
Mgp	Mouse	Lung	rep_2	35290801	7.23e-15
Mgp	Mouse	Lung	rep_3	35290801	5.26e-15
Mgp	Mouse	Lung	rep_4	35290801	3.04e-15
Mgp	Mouse	Brain	rep_1	35210624	1.74e-15
Mgp	Mouse	Brain	rep_2	35210624	1.74e-15
Mgp	Mouse	Brain	rep_3	35210624	1.82e-15
Mgp	Mouse	Brain	rep_4	35210624	2.34e-15
Mgp	Mouse	Brain	rep_5	35210624	3.62e-15
Mgp	Mouse	Brain	OFB_adpolb_rep1	33083725	1.39e-03
Mgp	Mouse	Brain	OFB_polb_rep8	33083725	1.66e-02

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_14_H&E
Liver_rep_18_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E
Brain_OFB_adpolb_rep1_H&E
Brain_OFB_polb_rep8_H&E

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Spatial pattern pathway has Mgp envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Mgp	GOBP_Ossification	Mouse	Spinal cord	CN94_E1	7.4e-06
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Spinal cord	CN94_E1	3.2e-07
Mgp	GOBP_Skeletal_System_Development	Mouse	Spinal cord	CN94_E1	5.6e-06
Mgp	GOBP_Cell_Aggregation	Mouse	Spinal cord	L7CN41_D1	2.1e-13
Mgp	GOBP_Biomineralization	Mouse	Spinal cord	L7CN45_C1	9.8e-07
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Spinal cord	L7CN45_C1	4.0e-08
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Spinal cord	L7CN45_C1	8.2e-06
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Mgp	GOBP_Bone_Mineralization	Mouse	Spinal cord	L7CN47_C1	9.1e-06
Mgp	GOBP_Connective_Tissue_Development	Mouse	Spinal cord	L7CN97_E2	8.6e-06
Mgp	GOBP_Cartilage_Development	Mouse	Spinal cord	L8CN17_E1	4.8e-07
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Mgp	GOBP_Biomineralization	Mouse	Brain	rep_71	4.1e-05
Mgp	GOBP_Connective_Tissue_Development	Mouse	Brain	rep_72	9.7e-06
Mgp	GOBP_Biomineralization	Mouse	Brain	rep_1	3.3e-12
Mgp	GOBP_Bone_Mineralization	Mouse	Brain	rep_1	3.0e-17
Mgp	GOBP_Cartilage_Development	Mouse	Brain	rep_1	1.2e-11
Mgp	GOBP_Cell_Aggregation	Mouse	Brain	rep_1	2.2e-19
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Brain	rep_1	2.8e-15
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Brain	rep_1	1.0e-17
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Brain	rep_2	3.8e-10
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Mgp	GOBP_Connective_Tissue_Development	Mouse	Brain	rep_3	3.3e-172
Mgp	GOBP_Ossification	Mouse	Brain	rep_3	6.7e-28
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	rep_3	5.2e-95
Mgp	GOBP_Skeletal_System_Development	Mouse	Brain	rep_3	3.3e-190
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	rep_3	7.3e-51
Mgp	GOBP_Biomineralization	Mouse	Embryo	rep_6	1.1e-14
Mgp	GOBP_Cartilage_Development	Mouse	Embryo	rep_6	6.1e-26
Mgp	GOBP_Cell_Aggregation	Mouse	Embryo	rep_6	7.4e-07
Mgp	GOBP_Connective_Tissue_Development	Mouse	Embryo	rep_6	1.0e-16
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_6	3.8e-12
Mgp	GOBP_Bone_Mineralization	Mouse	Embryo	rep_14	4.1e-29
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Embryo	rep_14	2.6e-25
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Embryo	rep_14	5.6e-15
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Embryo	rep_1	2.8e-203
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Embryo	rep_1	1.1e-08
Mgp	GOBP_Ossification	Mouse	Embryo	rep_2	6.7e-25
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_3	0.0e+00
Mgp	GOBP_Bone_Mineralization	Mouse	Embryo	rep_5	5.6e-13
Mgp	GOBP_Skeletal_System_Development	Mouse	Embryo	rep_6	3.1e-59
Mgp	GOBP_Cell_Aggregation	Mouse	Kidney	IRI	2.3e-44
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	Nep	1.3e-32
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Mgp	GOBP_Biomineralization	Mouse	Kidney	rep_2	6.9e-45
Mgp	GOBP_Bone_Mineralization	Mouse	Kidney	rep_2	4.5e-43
Mgp	GOBP_Connective_Tissue_Development	Mouse	Kidney	rep_2	9.8e-08
Mgp	GOBP_Ossification	Mouse	Kidney	rep_2	3.5e-66
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Kidney	rep_2	1.9e-18
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Kidney	rep_2	3.4e-28
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	rep_2	8.2e-110
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Kidney	rep_2	1.5e-38
Mgp	GOBP_Skeletal_System_Development	Mouse	Kidney	rep_2	7.5e-46
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Kidney	rep_2	1.2e-20
Mgp	GOBP_Biomineralization	Mouse	Liver	CN16-E1	3.4e-08
Mgp	GOBP_Skeletal_System_Development	Mouse	Liver	CN73-C1	9.4e-07
Mgp	GOBP_Bone_Mineralization	Mouse	Liver	rep_16	8.8e-09
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Liver	rep_16	8.2e-07
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Liver	rep_16	1.4e-10
Mgp	GOBP_Cell_Aggregation	Mouse	Liver	rep_20	4.1e-08
Mgp	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Mgp	GOBP_Biomineralization	Mouse	Lymph	MS-1	5.6e-08
Mgp	GOBP_Bone_Mineralization	Mouse	Lymph	MS-1	1.3e-11
Mgp	GOBP_Cartilage_Development	Mouse	Lymph	MS-1	1.7e-14
Mgp	GOBP_Cell_Aggregation	Mouse	Lymph	MS-1	1.3e-10
Mgp	GOBP_Connective_Tissue_Development	Mouse	Lymph	MS-1	1.4e-07
Mgp	GOBP_Ossification	Mouse	Lymph	MS-1	3.4e-11
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Lymph	MS-1	6.9e-13
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Lymph	MS-1	2.7e-16
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Lymph	MS-1	7.2e-15
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Lymph	MS-1	1.8e-12
Mgp	GOBP_Skeletal_System_Development	Mouse	Lymph	MS-1	2.6e-12
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Lymph	MS-1	8.7e-13
Mgp	GOBP_Bone_Mineralization	Mouse	Lung	rep_1	1.0e-15
Mgp	GOBP_Cartilage_Development	Mouse	Lung	rep_1	1.8e-13
Mgp	GOBP_Connective_Tissue_Development	Mouse	Lung	rep_1	2.6e-08
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Lung	rep_1	1.8e-11
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Lung	rep_1	5.7e-14
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Lung	rep_1	3.4e-20
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Lung	rep_1	4.0e-16
Mgp	GOBP_Cell_Aggregation	Mouse	Brain	rep_4	2.9e-112
Mgp	GOBP_Cell_Aggregation	Mouse	Brain	HP_ad_rep3	1.7e-07
Mgp	GOBP_Connective_Tissue_Development	Mouse	Brain	HP_ad_rep7	1.6e-08
Mgp	GOBP_Ossification	Mouse	Brain	HP_ad_rep7	2.8e-09
Mgp	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	HP_ad_rep7	1.1e-08
Mgp	GOBP_Skeletal_System_Development	Mouse	Brain	HP_ad_rep7	3.7e-09
Mgp	GOBP_Regulation_Of_Biomineralization	Mouse	Brain	HP_adpolb_rep5	1.4e-07
Mgp	GOBP_Biomineralization	Mouse	Brain	HP_polb_rep9	3.3e-07
Mgp	GOBP_Bone_Mineralization	Mouse	Brain	HP_polb_rep9	3.5e-07
Mgp	GOBP_Cartilage_Development	Mouse	Brain	HP_polb_rep9	8.8e-17
Mgp	GOBP_Regulation_Of_Bone_Mineralization	Mouse	Brain	HP_polb_rep9	6.9e-07
Mgp	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.1e-07
Mgp	GOBP_Regulation_Of_Ossification	Mouse	Brain	HP_wt_rep2	4.7e-09

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Mgp function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mgp function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mgp envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mgp

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mgp

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source