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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Sypl2 (spascer ID:17306)

Gene summary for Sypl2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Sypl2
	Gene ID	17306
	Gene name	synaptophysin-like 2
	Synonyms	AI552439\|Mg29
	Cytomap	3\|3 F2.3- F3
	Type of gene	protein-coding
	Description	synaptophysin-like protein 2mitsugumin 29
	Modification date	20220424
	UniProtAcc	O89104

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Sypl2	GO:0030672	synaptic vesicle membrane	21873635	Component

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Spatial pattern events for Sypl2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Sypl2	Mouse	Kidney	IRI	34003797	3.92e-15
Sypl2	Mouse	Kidney	Sham	34003797	2.58e-15
Sypl2	Mouse	Kidney	rep_1	34853151	2.42e-15
Sypl2	Mouse	Kidney	rep_3	34853151	2.94e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E

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Spatial pattern pathway has Sypl2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Sypl2	GOBP_Muscle_Structure_Development	Mouse	Spinal cord	CN94_E1	7.5e-07
Sypl2	GOBP_Plasma_Membrane_Organization	Mouse	Spinal cord	CN94_E1	3.1e-06
Sypl2	GOBP_T_Tubule_Organization	Mouse	Spinal cord	L7bCN02_E1	3.1e-07
Sypl2	GOBP_Cellular_Homeostasis	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Sypl2	GOBP_Cellular_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Spinal cord	L7CN45_C1	5.5e-10
Sypl2	GOBP_Chemical_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Sypl2	GOBP_Circulatory_System_Development	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Sypl2	GOBP_Divalent_Inorganic_Cation_Homeostasis	Mouse	Spinal cord	L7CN45_C1	7.4e-09
Sypl2	GOBP_Endomembrane_System_Organization	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Sypl2	GOBP_Head_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Sypl2	GOBP_Heart_Development	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Sypl2	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Sypl2	GOBP_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Sypl2	GOBP_Membrane_Organization	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Sypl2	GOBP_Metal_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.0e-08
Sypl2	GOBP_Midbrain_Development	Mouse	Spinal cord	L7CN45_C1	8.2e-08
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Sypl2	GOBP_Neural_Nucleus_Development	Mouse	Spinal cord	L7CN45_C1	6.4e-08
Sypl2	GOBP_Substantia_Nigra_Development	Mouse	Spinal cord	L7CN45_C1	4.4e-08
Sypl2	GOBP_Muscle_Cell_Development	Mouse	Spinal cord	L7CN47_C1	5.4e-06
Sypl2	GOBP_Cellular_Homeostasis	Mouse	Brain	rep_71	6.9e-06
Sypl2	GOBP_Cellular_Ion_Homeostasis	Mouse	Brain	rep_71	9.0e-05
Sypl2	GOBP_Chemical_Homeostasis	Mouse	Brain	rep_71	8.4e-05
Sypl2	GOBP_Divalent_Inorganic_Cation_Homeostasis	Mouse	Brain	rep_71	8.2e-05
Sypl2	GOBP_Ion_Homeostasis	Mouse	Brain	rep_71	9.0e-05
Sypl2	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	rep_71	4.0e-05
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Brain	rep_1	8.6e-30
Sypl2	GOBP_Endomembrane_System_Organization	Mouse	Brain	rep_1	7.8e-10
Sypl2	GOBP_Head_Development	Mouse	Brain	rep_1	3.9e-29
Sypl2	GOBP_Heart_Development	Mouse	Brain	rep_1	9.3e-14
Sypl2	GOBP_Muscle_Cell_Development	Mouse	Brain	rep_1	4.8e-19
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Brain	rep_1	2.6e-13
Sypl2	GOBP_T_Tubule_Organization	Mouse	Brain	rep_1	2.0e-44
Sypl2	GOBP_Circulatory_System_Development	Mouse	Brain	rep_3	1.3e-81
Sypl2	GOBP_Membrane_Organization	Mouse	Brain	rep_3	1.9e-41
Sypl2	GOBP_Midbrain_Development	Mouse	Brain	rep_3	2.8e-62
Sypl2	GOBP_Muscle_Structure_Development	Mouse	Brain	rep_3	3.3e-77
Sypl2	GOBP_Neural_Nucleus_Development	Mouse	Brain	rep_3	1.0e-56
Sypl2	GOBP_Plasma_Membrane_Organization	Mouse	Brain	rep_3	2.3e-56
Sypl2	GOBP_Substantia_Nigra_Development	Mouse	Brain	rep_3	8.3e-52
Sypl2	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Sypl2	GOBP_Circulatory_System_Development	Mouse	Embryo	rep_6	1.6e-12
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Embryo	rep_6	1.6e-07
Sypl2	GOBP_Muscle_Cell_Development	Mouse	Embryo	rep_14	9.1e-11
Sypl2	GOBP_T_Tubule_Organization	Mouse	Embryo	rep_14	5.7e-18
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Embryo	rep_1	3.0e-261
Sypl2	GOBP_Head_Development	Mouse	Embryo	rep_1	1.8e-91
Sypl2	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Sypl2	GOBP_Divalent_Inorganic_Cation_Homeostasis	Mouse	Embryo	rep_3	3.5e-19
Sypl2	GOBP_Metal_Ion_Homeostasis	Mouse	Embryo	rep_3	2.5e-10
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Kidney	Nep	4.2e-26
Sypl2	GOBP_Circulatory_System_Development	Mouse	Kidney	Nep	5.6e-37
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Kidney	rep_2	1.3e-23
Sypl2	GOBP_Circulatory_System_Development	Mouse	Kidney	rep_2	6.7e-139
Sypl2	GOBP_Endomembrane_System_Organization	Mouse	Kidney	rep_2	1.0e-161
Sypl2	GOBP_Head_Development	Mouse	Kidney	rep_2	1.9e-29
Sypl2	GOBP_Heart_Development	Mouse	Kidney	rep_2	4.8e-38
Sypl2	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Sypl2	GOBP_Membrane_Organization	Mouse	Kidney	rep_2	8.5e-74
Sypl2	GOBP_Midbrain_Development	Mouse	Kidney	rep_2	1.4e-46
Sypl2	GOBP_Muscle_Cell_Development	Mouse	Kidney	rep_2	1.8e-96
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Kidney	rep_2	4.1e-93
Sypl2	GOBP_Muscle_Structure_Development	Mouse	Kidney	rep_2	2.7e-36
Sypl2	GOBP_Neural_Nucleus_Development	Mouse	Kidney	rep_2	5.3e-13
Sypl2	GOBP_Plasma_Membrane_Organization	Mouse	Kidney	rep_2	2.5e-150
Sypl2	GOBP_Substantia_Nigra_Development	Mouse	Kidney	rep_2	9.8e-18
Sypl2	GOBP_T_Tubule_Organization	Mouse	Kidney	rep_2	1.3e-26
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Liver	rep_16	8.2e-15
Sypl2	GOBP_Divalent_Inorganic_Cation_Homeostasis	Mouse	Liver	rep_16	5.1e-11
Sypl2	GOBP_Head_Development	Mouse	Liver	rep_16	4.3e-18
Sypl2	GOBP_T_Tubule_Organization	Mouse	Liver	rep_16	3.8e-07
Sypl2	GOBP_Cellular_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Sypl2	GOBP_Cellular_Ion_Homeostasis	Mouse	Lymph	MS-1	4.0e-14
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Lymph	MS-1	3.8e-07
Sypl2	GOBP_Chemical_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Sypl2	GOBP_Circulatory_System_Development	Mouse	Lymph	MS-1	1.6e-11
Sypl2	GOBP_Divalent_Inorganic_Cation_Homeostasis	Mouse	Lymph	MS-1	4.9e-13
Sypl2	GOBP_Endomembrane_System_Organization	Mouse	Lymph	MS-1	2.5e-09
Sypl2	GOBP_Heart_Development	Mouse	Lymph	MS-1	8.3e-10
Sypl2	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Sypl2	GOBP_Ion_Homeostasis	Mouse	Lymph	MS-1	7.3e-10
Sypl2	GOBP_Membrane_Organization	Mouse	Lymph	MS-1	5.8e-20
Sypl2	GOBP_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	4.9e-13
Sypl2	GOBP_Muscle_Cell_Development	Mouse	Lymph	MS-1	6.4e-10
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Lymph	MS-1	1.8e-07
Sypl2	GOBP_Muscle_Structure_Development	Mouse	Lymph	MS-1	3.8e-09
Sypl2	GOBP_Neural_Nucleus_Development	Mouse	Lymph	MS-1	5.9e-07
Sypl2	GOBP_Plasma_Membrane_Organization	Mouse	Lymph	MS-1	2.6e-09
Sypl2	GOBP_Substantia_Nigra_Development	Mouse	Lymph	MS-1	5.9e-07
Sypl2	GOBP_T_Tubule_Organization	Mouse	Lymph	MS-2	1.5e-09
Sypl2	GOBP_T_Tubule_Organization	Mouse	Lung	rep_1	2.0e-10
Sypl2	GOBP_T_Tubule_Organization	Mouse	Brain	rep_4	1.4e-20
Sypl2	GOBP_Central_Nervous_System_Development	Mouse	Brain	HP_ad_rep7	2.3e-07
Sypl2	GOBP_Head_Development	Mouse	Brain	HP_ad_rep7	3.0e-07
Sypl2	GOBP_Heart_Development	Mouse	Brain	HP_ad_rep7	2.4e-08
Sypl2	GOBP_Muscle_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	5.5e-07
Sypl2	GOBP_Cellular_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-09
Sypl2	GOBP_Cellular_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.5e-09
Sypl2	GOBP_Chemical_Homeostasis	Mouse	Brain	HP_polb_rep9	9.6e-10
Sypl2	GOBP_Circulatory_System_Development	Mouse	Brain	HP_polb_rep9	3.1e-09
Sypl2	GOBP_Endomembrane_System_Organization	Mouse	Brain	HP_polb_rep9	6.0e-11
Sypl2	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Sypl2	GOBP_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.5e-08
Sypl2	GOBP_Membrane_Organization	Mouse	Brain	HP_polb_rep9	1.4e-13
Sypl2	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-07

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Sypl2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Sypl2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Sypl2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Sypl2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Sypl2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source