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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mettl1 (spascer ID:17299)

Gene summary for Mettl1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mettl1
	Gene ID	17299
	Gene name	methyltransferase like 1
	Synonyms	2810012D02Rik
	Cytomap	10\|10 D3
	Type of gene	protein-coding
	Description	tRNA (guanine-N(7)-)-methyltransferasemRNA (guanine-N(7)-)-methyltransferasemiRNA (guanine-N(7)-)-methyltransferase
	Modification date	20220424
	UniProtAcc	Q9Z120

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mettl1	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	21873635	Function
Mettl1	GO:0030488	tRNA methylation	21873635	Process
Mettl1	GO:0036265	RNA (guanine-N7)-methylation	21873635	Process
Mettl1	GO:0043527	tRNA methyltransferase complex	21873635	Component

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Spatial pattern events for Mettl1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mettl1	Mouse	Brain	rep_3	35141374	2.06e-08
Mettl1	Mouse	Brain	rep_4	35141374	7.35e-07
Mettl1	Mouse	Brain	rep_5	35141374	1.47e-15
Mettl1	Mouse	Brain	rep_6	35141374	6.66e-10
Mettl1	Mouse	Embryo	rep_5	33188776	1.44e-07
Mettl1	Mouse	Kidney	CLP	34003797	9.01e-06
Mettl1	Mouse	Kidney	Sham	34003797	3.84e-13
Mettl1	Mouse	Intestine	rep_4	35149721	2.82e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_Sham_H&E

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Spatial pattern pathway has Mettl1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mettl1	GOBP_Methylation	Mouse	Spinal cord	CN94_E1	7.7e-06
Mettl1	GOBP_Trna_Methylation	Mouse	Spinal cord	L7bCN02_E1	4.6e-06
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Spinal cord	L7CN41_C2	8.0e-07
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Mettl1	GOBP_Ncrna_Processing	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Mettl1	GOBP_Rna_Methylation	Mouse	Spinal cord	L7CN45_C1	8.4e-07
Mettl1	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Mettl1	GOBP_Trna_Processing	Mouse	Spinal cord	L7CN47_C1	3.7e-07
Mettl1	GOBP_Rna_Modification	Mouse	Spinal cord	L8CN17_E1	4.8e-08
Mettl1	GOBP_Trna_Methylation	Mouse	Brain	rep_19	3.6e-05
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Brain	rep_21	2.2e-05
Mettl1	GOBP_Rna_Methylation	Mouse	Brain	rep_27	1.7e-10
Mettl1	GOBP_Trna_Modification	Mouse	Brain	rep_27	7.7e-08
Mettl1	GOBP_Trna_Processing	Mouse	Brain	rep_27	1.9e-07
Mettl1	GOBP_Methylation	Mouse	Brain	rep_3	3.9e-199
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	rep_3	1.8e-46
Mettl1	GOBP_Ncrna_Processing	Mouse	Brain	rep_3	5.1e-21
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Brain	rep_3	1.5e-146
Mettl1	GOBP_Rna_Methylation	Mouse	Brain	rep_3	9.0e-81
Mettl1	GOBP_Rna_Modification	Mouse	Brain	rep_3	1.8e-211
Mettl1	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_3	2.5e-229
Mettl1	GOBP_Trna_Methylation	Mouse	Brain	rep_3	1.4e-08
Mettl1	GOBP_Trna_Modification	Mouse	Brain	rep_3	2.1e-177
Mettl1	GOBP_Trna_Processing	Mouse	Brain	rep_3	7.2e-211
Mettl1	GOBP_Ncrna_Processing	Mouse	Embryo	rep_14	2.7e-41
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Embryo	rep_14	1.0e-23
Mettl1	GOBP_Rna_Methylation	Mouse	Embryo	rep_14	2.0e-39
Mettl1	GOBP_Rna_Modification	Mouse	Embryo	rep_14	3.1e-46
Mettl1	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Mettl1	GOBP_Trna_Methylation	Mouse	Embryo	rep_14	4.3e-39
Mettl1	GOBP_Trna_Modification	Mouse	Embryo	rep_14	1.2e-44
Mettl1	GOBP_Trna_Processing	Mouse	Embryo	rep_14	1.5e-48
Mettl1	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Mettl1	GOBP_Methylation	Mouse	Embryo	rep_3	0.0e+00
Mettl1	GOBP_Methylation	Mouse	Kidney	rep_2	2.7e-54
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-81
Mettl1	GOBP_Ncrna_Processing	Mouse	Kidney	rep_2	5.7e-81
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Kidney	rep_2	1.3e-59
Mettl1	GOBP_Rna_Methylation	Mouse	Kidney	rep_2	1.2e-52
Mettl1	GOBP_Rna_Modification	Mouse	Kidney	rep_2	7.1e-48
Mettl1	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Kidney	rep_2	1.9e-92
Mettl1	GOBP_Trna_Methylation	Mouse	Kidney	rep_2	7.1e-29
Mettl1	GOBP_Trna_Modification	Mouse	Kidney	rep_2	5.9e-39
Mettl1	GOBP_Trna_Processing	Mouse	Kidney	rep_2	1.3e-62
Mettl1	GOBP_Trna_Methylation	Mouse	Liver	CN16-E1	5.4e-12
Mettl1	GOBP_Rna_Methylation	Mouse	Liver	CN65-C1	6.8e-09
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-08
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Liver	rep_15	6.0e-11
Mettl1	GOBP_Rna_Methylation	Mouse	Liver	rep_15	5.5e-08
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Brain	rep_1	2.7e-05
Mettl1	GOBP_Methylation	Mouse	Lymph	MS-1	2.5e-08
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Mettl1	GOBP_Ncrna_Processing	Mouse	Lymph	MS-1	7.2e-09
Mettl1	GOBP_Rna_Methylation	Mouse	Lymph	MS-1	7.5e-10
Mettl1	GOBP_Rna_Modification	Mouse	Lymph	MS-1	9.8e-15
Mettl1	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Lymph	MS-1	1.0e-08
Mettl1	GOBP_Trna_Modification	Mouse	Lymph	MS-1	2.7e-09
Mettl1	GOBP_Trna_Processing	Mouse	Lymph	MS-1	7.9e-12
Mettl1	GOBP_Trna_Methylation	Mouse	Lymph	MS-2	4.1e-08
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_4	2.6e-107
Mettl1	GOBP_Methylation	Mouse	Brain	rep_7	1.2e-08
Mettl1	GOBP_Rna_Methylation	Mouse	Brain	rep_7	3.1e-08
Mettl1	GOBP_Rna_Modification	Mouse	Brain	rep_7	3.9e-16
Mettl1	GOBP_Trna_Modification	Mouse	Brain	rep_7	1.8e-16
Mettl1	GOBP_Trna_Processing	Mouse	Brain	rep_7	2.4e-14
Mettl1	GOBP_Rna_Guanine_N7_Methylation	Mouse	Brain	HP_ad_rep3	2.2e-09
Mettl1	GOBP_Methylation	Mouse	Brain	HP_ad_rep7	1.4e-10
Mettl1	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-10
Mettl1	GOBP_Rna_Methylation	Mouse	Brain	HP_ad_rep7	4.1e-11
Mettl1	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Mettl1	GOBP_Trna_Methylation	Mouse	Brain	HP_ad_rep7	5.0e-10
Mettl1	GOBP_Trna_Modification	Mouse	Brain	HP_ad_rep7	3.1e-10
Mettl1	GOBP_Ncrna_Processing	Mouse	Brain	HP_adpolb_rep1	3.5e-08
Mettl1	GOBP_Rna_Modification	Mouse	Brain	HP_adpolb_rep1	5.1e-09
Mettl1	GOBP_Trna_Metabolic_Process	Mouse	Brain	HP_adpolb_rep5	9.9e-10

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Mettl1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mettl1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mettl1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mettl1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mettl1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source