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Spatial pattern gene: Mest (spascer ID:17294) |
Gene summary for Mest |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Mest | Gene ID | 17294 |
| Gene name | mesoderm specific transcript |
| Synonyms | AA408879|AI256745|Peg1 |
| Cytomap | 6 A3.3|6 12.53 cM |
| Type of gene | protein-coding |
| Description | mesoderm-specific transcript proteinpaternally-expressed gene 1 protein |
| Modification date | 20220426 |
| UniProtAcc | Q07646 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Mest | GO:0005783 | endoplasmic reticulum | 21873635 | Component |
| Mest | GO:0010883 | regulation of lipid storage | 21873635 | Process |
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Spatial pattern events for Mest |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Mest | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Mest | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Mest | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Mest | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Mest | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Mest | Mouse | Brain | 19A | 32637622 | 3.18e-06 |
| Mest | Mouse | Brain | 23B | 32637622 | 3.66e-07 |
| Mest | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Mest | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Mest | Mouse | Brain | rep_3 | 35141374 | 1.22e-08 |
| Mest | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Mest | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Mest | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Mest | Mouse | Embryo | 1D | 34210887 | 2.07e-14 |
| Mest | Mouse | Embryo | 1E | 34210887 | 7.50e-15 |
| Mest | Mouse | Embryo | 1F | 34210887 | 7.91e-15 |
| Mest | Mouse | Embryo | 1G | 34210887 | 6.15e-15 |
| Mest | Mouse | Embryo | 2G | 34210887 | 1.06e-14 |
| Mest | Mouse | Embryo | 2H | 34210887 | 5.31e-15 |
| Mest | Mouse | Embryo | 3D | 34210887 | 8.93e-15 |
| Mest | Mouse | Embryo | 3F | 34210887 | 5.82e-15 |
| Mest | Mouse | Embryo | 3G | 34210887 | 8.80e-15 |
| Mest | Mouse | Embryo | 3H | 34210887 | 2.20e-14 |
| Mest | Mouse | Embryo | 4A | 34210887 | 2.38e-14 |
| Mest | Mouse | Embryo | 4C | 34210887 | 1.65e-14 |
| Mest | Mouse | Embryo | 4D | 34210887 | 7.75e-15 |
| Mest | Mouse | Embryo | 4E | 34210887 | 4.53e-15 |
| Mest | Mouse | Embryo | rep_1 | 33188776 | 9.94e-15 |
| Mest | Mouse | Embryo | rep_2 | 33188776 | 1.37e-14 |
| Mest | Mouse | Embryo | rep_3 | 33188776 | 1.13e-14 |
| Mest | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Mest | Mouse | Embryo | rep_5 | 33188776 | 1.40e-14 |
| Mest | Mouse | Embryo | rep_6 | 33188776 | 8.90e-07 |
| Mest | Mouse | Embryo | rep_7 | 33188776 | 6.94e-15 |
| Mest | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Mest | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Mest | Mouse | Embryo | rep_14 | 33188776 | 6.29e-09 |
| Mest | Mouse | Embryo | rep_15 | 33188776 | 2.04e-14 |
| Mest | Mouse | Kidney | rep_1 | 33976190 | 1.48e-12 |
| Mest | Mouse | Kidney | rep_2 | 33976190 | 2.74e-11 |
| Mest | Mouse | Kidney | rep_3 | 33976190 | 4.61e-10 |
| Mest | Mouse | Kidney | rep_4 | 33976190 | 6.10e-06 |
| Mest | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Mest | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Mest | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Mest | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Mest | Mouse | Brain | rep_4 | 35027729 | 3.10e-15 |
| Mest | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Mest | Mouse | Brain | B02_E1 | 32702314 | 4.68e-11 |
| Mest | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Mest | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Mest | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Mest | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Mest | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Mest | Mouse | Brain | OFB_wt_rep1 | 33083725 | 1.61e-03 |
| Mest | Mouse | Brain | OFB_wt_rep5 | 33083725 | 1.58e-08 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_2_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B02_E1_H&E  |  |
Brain_OFB_wt_rep1_H&E  | |
Brain_OFB_wt_rep5_H&E  |
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Spatial pattern pathway has Mest envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Spinal cord | CN94_E1 | 5.7e-06 |
| Mest | GOBP_Mesoderm_Development | Mouse | Spinal cord | CN94_E1 | 5.8e-06 |
| Mest | GOBP_Lipid_Storage | Mouse | Spinal cord | L7CN45_C1 | 5.3e-06 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Spinal cord | L7CN45_C1 | 1.5e-06 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Brain | rep_27 | 2.9e-05 |
| Mest | GOBP_Lipid_Localization | Mouse | Brain | rep_3 | 2.0e-22 |
| Mest | GOBP_Lipid_Storage | Mouse | Brain | rep_3 | 1.5e-67 |
| Mest | GOBP_Mesoderm_Development | Mouse | Brain | rep_3 | 3.3e-168 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Brain | rep_3 | 2.9e-94 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Brain | rep_4 | 5.1e-13 |
| Mest | GOBP_Lipid_Storage | Mouse | Embryo | rep_14 | 7.4e-15 |
| Mest | GOBP_Mesoderm_Development | Mouse | Embryo | rep_14 | 5.8e-16 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Embryo | rep_14 | 5.3e-19 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Kidney | Nep | 4.2e-26 |
| Mest | GOBP_Lipid_Storage | Mouse | Kidney | Sham | 6.9e-26 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Kidney | Sham | 2.2e-46 |
| Mest | GOBP_Lipid_Localization | Mouse | Kidney | rep_2 | 1.1e-173 |
| Mest | GOBP_Lipid_Storage | Mouse | Kidney | rep_2 | 7.7e-42 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Kidney | rep_2 | 8.4e-58 |
| Mest | GOBP_Mesoderm_Development | Mouse | Kidney | rep_2 | 2.4e-61 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Kidney | rep_2 | 6.4e-39 |
| Mest | GOBP_Lipid_Storage | Mouse | Liver | CN73-C1 | 6.1e-09 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Liver | CN73-C1 | 1.3e-07 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Liver | rep_16 | 4.3e-11 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Lymph | MS-1 | 1.0e-10 |
| Mest | GOBP_Mesoderm_Development | Mouse | Lymph | MS-1 | 5.8e-10 |
| Mest | GOBP_Regulation_Of_Lipid_Storage | Mouse | Brain | HP_ad_rep3 | 7.8e-08 |
| Mest | GOBP_Maintenance_Of_Location | Mouse | Brain | HP_ad_rep7 | 1.5e-07 |
| Mest | GOBP_Mesoderm_Development | Mouse | Brain | HP_ad_rep7 | 1.9e-08 |
| Mest | GOBP_Lipid_Storage | Mouse | Brain | HP_adpolb_rep1 | 4.7e-10 |
| Mest | GOBP_Lipid_Localization | Mouse | Brain | HP_polb_rep9 | 1.4e-07 |
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Mest function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Mest function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Mest envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Mest |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Mest |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Mest | C0043094 | Weight Gain | 1 | CTD_human |
