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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Meg3 (spascer ID:17263)

Gene summary for Meg3

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Meg3

Gene ID

17263

Gene namematernally expressed 3
Synonyms2900016C05Rik|3110050O07Rik|6330408G06Rik|AI425946|AW108224|D12Bwg1266e|Gtl2|R74756|R75394
Cytomap12 F1|12 60.25 cM
Type of genencRNA
DescriptionGTL2, imprinted maternally expressed untranslated mRNAgene trap locus 2maternally expressed gene 3
Modification date20220515
UniProtAcc


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory

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Spatial pattern events for Meg3

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Meg3MouseSpinal cordL7bCN01_E2 309485522.58e-07
Meg3MouseSpinal cordL7bCN02_E1 309485523.68e-06
Meg3MouseSpinal cordL7CN63_C2 309485523.57e-07
Meg3MouseSpinal cordL7CN68_C1 309485527.42e-09
Meg3MouseSpinal cordL7CN69_C1 309485528.99e-06
Meg3MouseSpinal cordL7CN69_D1 309485522.44e-07
Meg3MouseSpinal cordL7CN79_C1 309485521.81e-11
Meg3MouseSpinal cordL7CN81_E2 309485523.86e-08
Meg3MouseSpinal cordL7CN91_C1 309485523.56e-08
Meg3MouseSpinal cordL7CN91_D1 309485528.77e-12
Meg3MouseSpinal cordL7CN92_D1 309485521.17e-07
Meg3MouseSpinal cordL7CN93_D1 309485523.90e-07
Meg3MouseSpinal cordL7CN93_E2 309485521.90e-06
Meg3MouseSpinal cordL7CN94_D1 309485523.32e-07
Meg3MouseSpinal cordL7CN95_C2 309485523.58e-07
Meg3MouseSpinal cordL7CN96_E2 309485529.13e-11
Meg3MouseSpinal cordL8CN18_E1 309485521.56e-07
Meg3MouseSpinal cordL8CN22_D1 309485524.79e-08
Meg3MouseSpinal cordL8CN22_E1 309485522.14e-09
Meg3MouseBrainS1 344135152.07e-15
Meg3MouseBrainS2 344135151.56e-15
Meg3MouseBrainS3 344135151.64e-15
Meg3MouseBrainS4 344135151.37e-15
Meg3MouseBrainS6 344135151.46e-15
Meg3MouseBrainS7 344135151.55e-15
Meg3MouseEmbryo1D 342108871.46e-14
Meg3MouseEmbryo1E 342108877.50e-15
Meg3MouseEmbryo1F 342108877.91e-15
Meg3MouseEmbryo1G 342108876.15e-15
Meg3MouseEmbryo2G 342108872.48e-08
Meg3MouseEmbryo2H 342108875.31e-15
Meg3MouseEmbryo3D 342108872.78e-14
Meg3MouseEmbryo3F 342108875.82e-15
Meg3MouseEmbryo3G 342108878.80e-15
Meg3MouseEmbryo3H 342108871.61e-07
Meg3MouseEmbryo4A 342108872.38e-14
Meg3MouseEmbryo4C 342108871.65e-14
Meg3MouseEmbryo4D 342108871.36e-14
Meg3MouseEmbryo4E 342108874.53e-15
Meg3MouseKidneyrep_1 339761902.61e-11
Meg3MouseBrainrep_1 334690251.30e-15
Meg3MouseLiverrep_18 350210635.68e-06
Meg3MouseBrainrep_1 350277291.66e-15
Meg3MouseBrainrep_2 350277291.57e-15
Meg3MouseBrainrep_3 350277291.32e-15
Meg3MouseBrainrep_4 350277291.76e-15
Meg3MouseBrainrep_5 350277291.46e-15
Meg3MouseIntestinerep_1 351497214.80e-08
Meg3MouseIntestinerep_2 351497215.49e-15
Meg3MouseIntestinerep_3 351497215.21e-15
Meg3MouseIntestinerep_4 351497212.30e-15
Meg3MouseBrainB02_D1 327023141.50e-14
Meg3MouseBrainB02_E1 327023144.79e-11
Meg3MouseBrainB03_D2 327023146.48e-14
Meg3MouseBrainB04_D1 327023142.29e-10
Meg3MouseBrainB04_E1 327023141.28e-07
Meg3MouseBrainB06_E1 327023144.71e-11
Meg3MouseBrainB07_C2 327023144.40e-11
Meg3MouseBrainN02_C1 327023144.93e-14
Meg3MouseBrainN02_D1 327023141.02e-09
Meg3MouseBrainN03_D2 327023141.67e-07
Meg3MouseBrainN05_D2 327023141.09e-07
Meg3MouseBrainN07_C1 327023141.28e-12
Meg3MouseTesticlerep_4 347316001.30e-15
Meg3MouseLymphB1 01.11e-14
Meg3MouseBrainrep_1 352106241.74e-15
Meg3MouseBrainrep_2 352106241.74e-15
Meg3MouseBrainrep_3 352106241.82e-15
Meg3MouseBrainrep_4 352106242.34e-15
Meg3MouseBrainrep_5 352106242.07e-15
Meg3MouseBrainrep_6 352106242.05e-15
Meg3MouseBrainrep_7 352106241.87e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_rep_1_H&E
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Brain_rep_1_H&E
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Liver_rep_18_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_D1_H&E
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Brain_B02_E1_H&E
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Brain_B03_D2_H&E
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Brain_B04_D1_H&E
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Brain_B04_E1_H&E
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Brain_B06_E1_H&E
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Brain_B07_C2_H&E
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Brain_N02_C1_H&E
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Brain_N02_D1_H&E
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Brain_N03_D2_H&E
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Brain_N05_D2_H&E
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Brain_N07_C1_H&E
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Spatial pattern pathway has Meg3 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Meg3GOBP_GrowthMouseSpinal cordCN94_E1 1.2e-06
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseSpinal cordCN94_E1 5.8e-06
Meg3GOBP_Negative_Regulation_Of_GrowthMouseSpinal cordCN94_E1 4.1e-06
Meg3GOBP_Cell_GrowthMouseSpinal cordL7CN45_C1 8.5e-07
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseSpinal cordL7CN45_C1 5.6e-06
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseSpinal cordL7CN45_C1 7.4e-09
Meg3GOBP_Regulation_Of_GrowthMouseSpinal cordL7CN45_C1 1.3e-06
Meg3GOBP_Cell_GrowthMouseBrainrep_27 5.0e-07
Meg3GOBP_GrowthMouseBrainrep_27 5.5e-05
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseBrainrep_27 4.2e-05
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseBrainrep_27 4.7e-05
Meg3GOBP_Negative_Regulation_Of_GrowthMouseBrainrep_71 9.4e-05
Meg3GOBP_Cell_GrowthMouseBrainrep_1 2.4e-12
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseBrainrep_3 1.6e-37
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseBrainrep_31.1e-139
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseBrainrep_38.5e-206
Meg3GOBP_GrowthMouseBrainrep_7 5.0e-09
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseEmbryorep_14 2.7e-17
Meg3GOBP_Negative_Regulation_Of_GrowthMouseEmbryorep_14 6.2e-17
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseEmbryorep_14 1.4e-11
Meg3GOBP_GrowthMouseEmbryorep_1 5.0e-12
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseEmbryorep_1 9.4e-07
Meg3GOBP_Regulation_Of_GrowthMouseEmbryorep_1 7.1e-83
Meg3GOBP_Cell_GrowthMouseKidneyNep 1.1e-16
Meg3GOBP_GrowthMouseKidneyNep 1.1e-16
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseKidneyrep_2 1.0e-19
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseKidneyrep_2 1.1e-92
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseLiverrep_16 6.2e-22
Meg3GOBP_Negative_Regulation_Of_GrowthMouseLiverrep_16 8.7e-10
Meg3GOBP_Regulation_Of_GrowthMouseLiverrep_16 1.5e-07
Meg3GOBP_Cell_GrowthMouseLymphMS-1 4.5e-14
Meg3GOBP_GrowthMouseLymphMS-1 4.5e-14
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseLymphMS-1 2.8e-08
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseLymphMS-1 6.3e-11
Meg3GOBP_Negative_Regulation_Of_GrowthMouseLymphMS-1 5.1e-08
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseLymphMS-1 7.1e-09
Meg3GOBP_Regulation_Of_GrowthMouseLymphMS-1 8.9e-15
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseLungrep_1 4.5e-23
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseLungrep_1 1.6e-15
Meg3GOBP_Cell_GrowthMouseBrainrep_4 1.7e-17
Meg3GOBP_GrowthMouseBrainHP_ad_rep7 3.9e-09
Meg3GOBP_Negative_Regulation_Of_Cell_GrowthMouseBrainHP_ad_rep7 4.3e-07
Meg3GOBP_Negative_Regulation_Of_Gene_ExpressionMouseBrainHP_ad_rep7 2.1e-08
Meg3GOBP_Posttranscriptional_Regulation_Of_Gene_ExpressionMouseBrainHP_ad_rep7 1.9e-10
Meg3GOBP_Regulation_Of_GrowthMouseBrainHP_ad_rep7 5.8e-07
Meg3GOBP_Cell_GrowthMouseBrainHP_polb_rep9 1.7e-11
Meg3GOBP_Negative_Regulation_Of_GrowthMouseBrainHP_polb_rep9 2.8e-08

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Meg3 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Meg3 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Meg3 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Meg3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Meg3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Meg3C1842466Uniparental disomy, paternal, chromosome 142ORPHANET