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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Mcm7 (spascer ID:17220)

Gene summary for Mcm7

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Mcm7

Gene ID

17220

Gene nameminichromosome maintenance complex component 7
SynonymsAI747533|Mcmd7|mCDC47
Cytomap5|5 G2
Type of geneprotein-coding
DescriptionDNA replication licensing factor MCM7CDC47 homologmini chromosome maintenance deficient 7minichromosome maintenance deficient 7
Modification date20220424
UniProtAcc

Q61881


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Mcm7

GO:0000727

double-strand break repair via break-induced replication

21873635

Process
Mcm7

GO:0003697

single-stranded DNA binding

21873635

Function
Mcm7

GO:0005634

nucleus

21873635

Component
Mcm7

GO:0006268

DNA unwinding involved in DNA replication

21873635

Process
Mcm7

GO:0006270

DNA replication initiation

21873635

Process
Mcm7

GO:0006271

DNA strand elongation involved in DNA replication

21873635

Process
Mcm7

GO:0017116

single-stranded DNA helicase activity

21873635

Function
Mcm7

GO:0042555

MCM complex

21873635

Component

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Spatial pattern events for Mcm7

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Mcm7MouseBrain06B 326376221.09e-09
Mcm7MouseEmbryorep_2 331887763.50e-14
Mcm7MouseEmbryorep_3 331887768.14e-14
Mcm7MouseEmbryorep_7 331887762.36e-07
Mcm7MouseEmbryorep_13 331887764.49e-15
Mcm7MouseKidneyrep_3 348531512.59e-06
Mcm7MouseKidneyrep_5 348531513.18e-15
Mcm7MouseBrainrep_1 334690251.30e-15
Mcm7MouseIntestinerep_4 351497212.30e-15
Mcm7MouseLymphA1 03.29e-15
Mcm7MouseLymphB1 03.66e-15
Mcm7MouseLungrep_1 352908016.56e-15
Mcm7MouseLungrep_2 352908012.73e-09
Mcm7MouseLungrep_3 352908013.59e-11

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_rep_3_H&E
boxplot
boxplot
Kidney_rep_5_H&E
boxplot
boxplot
Brain_rep_1_H&E
boxplot
Lung_rep_1_H&E
boxplot
boxplot
Lung_rep_2_H&E
boxplot
boxplot
Lung_rep_3_H&E
boxplot
boxplot


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Spatial pattern pathway has Mcm7 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseSpinal cordCN78_C1 6.5e-06
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseSpinal cordCN90_C1 3.8e-06
Mcm7GOBP_Cell_CycleMouseSpinal cordCN94_E1 1.1e-06
Mcm7GOBP_Cell_Cycle_Dna_ReplicationMouseSpinal cordCN94_E1 7.4e-07
Mcm7GOBP_Cell_Cycle_ProcessMouseSpinal cordCN94_E1 3.8e-06
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseSpinal cordCN94_E1 8.0e-06
Mcm7GOBP_Dna_Metabolic_ProcessMouseSpinal cordCN94_E1 2.7e-06
Mcm7GOBP_Recombinational_RepairMouseSpinal cordCN94_E1 8.5e-06
Mcm7GOBP_Response_To_Endogenous_StimulusMouseSpinal cordCN94_E1 2.2e-06
Mcm7GOBP_Cell_Cycle_Phase_TransitionMouseSpinal cordL7bCN02_E1 1.5e-06
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseSpinal cordL7bCN02_E1 3.4e-06
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseSpinal cordL7CN30_C2 3.2e-06
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseSpinal cordL7CN45_C1 6.7e-08
Mcm7GOBP_Chromosome_OrganizationMouseSpinal cordL7CN45_C1 3.4e-08
Mcm7GOBP_Dna_Conformation_ChangeMouseSpinal cordL7CN45_C1 8.1e-07
Mcm7GOBP_Dna_RecombinationMouseSpinal cordL7CN45_C1 5.6e-07
Mcm7GOBP_Dna_RepairMouseSpinal cordL7CN45_C1 9.4e-06
Mcm7GOBP_Dna_ReplicationMouseSpinal cordL7CN45_C1 2.8e-07
Mcm7GOBP_Dna_Replication_InitiationMouseSpinal cordL7CN45_C1 6.9e-06
Mcm7GOBP_Dna_Strand_ElongationMouseSpinal cordL7CN45_C1 3.7e-06
Mcm7GOBP_Double_Strand_Break_RepairMouseSpinal cordL7CN45_C1 5.4e-06
Mcm7GOBP_Mitotic_Cell_CycleMouseSpinal cordL7CN45_C1 2.4e-08
Mcm7GOBP_Response_To_Growth_FactorMouseSpinal cordL7CN45_C1 4.2e-06
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseSpinal cordL7CN47_C1 6.6e-06
Mcm7GOBP_Dna_Geometric_ChangeMouseSpinal cordL7CN47_C1 2.6e-06
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseSpinal cordL7CN60_D1 3.3e-06
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseSpinal cordL8CN11_C1 3.6e-13
Mcm7GOBP_Dna_Conformation_ChangeMouseBrainrep_11 3.6e-05
Mcm7GOBP_Dna_Geometric_ChangeMouseBrainrep_11 2.1e-05
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseBrainrep_21 4.2e-05
Mcm7GOBP_Cell_CycleMouseBrainrep_27 8.4e-07
Mcm7GOBP_Dna_ReplicationMouseBrainrep_27 6.4e-06
Mcm7GOBP_Mitotic_Cell_CycleMouseBrainrep_27 1.1e-05
Mcm7GOBP_Dna_Strand_ElongationMouseBrainrep_41 1.1e-05
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseBrainrep_41 1.2e-09
Mcm7GOBP_Cell_CycleMouseBrainrep_1 7.0e-10
Mcm7GOBP_Cell_Cycle_Dna_ReplicationMouseBrainrep_1 3.4e-08
Mcm7GOBP_Cell_Cycle_Phase_TransitionMouseBrainrep_1 1.6e-31
Mcm7GOBP_Cell_Cycle_ProcessMouseBrainrep_1 6.7e-14
Mcm7GOBP_Chromosome_OrganizationMouseBrainrep_1 3.9e-07
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseBrainrep_1 1.5e-17
Mcm7GOBP_Dna_Metabolic_ProcessMouseBrainrep_1 1.1e-07
Mcm7GOBP_Dna_RecombinationMouseBrainrep_1 6.8e-13
Mcm7GOBP_Dna_ReplicationMouseBrainrep_1 4.3e-10
Mcm7GOBP_Dna_Replication_InitiationMouseBrainrep_1 1.9e-10
Mcm7GOBP_Dna_Strand_ElongationMouseBrainrep_1 5.6e-11
Mcm7GOBP_Double_Strand_Break_RepairMouseBrainrep_1 5.6e-13
Mcm7GOBP_Mitotic_Cell_CycleMouseBrainrep_1 1.5e-25
Mcm7GOBP_Recombinational_RepairMouseBrainrep_1 5.8e-08
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseBrainrep_33.0e-140
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseBrainrep_35.0e-192
Mcm7GOBP_Dna_Conformation_ChangeMouseBrainrep_3 7.4e-54
Mcm7GOBP_Dna_Geometric_ChangeMouseBrainrep_34.9e-189
Mcm7GOBP_Dna_RepairMouseBrainrep_34.0e-216
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseBrainrep_3 1.8e-40
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseBrainrep_3 7.8e-86
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseBrainrep_35.3e-122
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainrep_3 3.0e-62
Mcm7GOBP_Response_To_Endogenous_StimulusMouseBrainrep_3 6.4e-96
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseBrainrep_3 1.4e-98
Mcm7GOBP_Response_To_Growth_FactorMouseBrainrep_3 2.7e-45
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseBrainrep_34.2e-143
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseBrainrep_5 5.3e-09
Mcm7GOBP_Dna_Conformation_ChangeMouseEmbryorep_14 2.1e-08
Mcm7GOBP_Dna_Geometric_ChangeMouseEmbryorep_14 5.1e-11
Mcm7GOBP_Dna_Replication_InitiationMouseEmbryorep_14 3.1e-28
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseEmbryorep_14 3.6e-17
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseEmbryorep_14 1.0e-37
Mcm7GOBP_Double_Strand_Break_RepairMouseEmbryorep_14 1.4e-07
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseEmbryorep_14 1.6e-37
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseEmbryorep_14 2.2e-11
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseEmbryorep_14 2.1e-08
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseEmbryorep_2 1.4e-08
Mcm7GOBP_Dna_Metabolic_ProcessMouseEmbryorep_27.2e-216
Mcm7GOBP_Dna_RecombinationMouseEmbryorep_2 0.0e+00
Mcm7GOBP_Dna_RepairMouseEmbryorep_21.6e-282
Mcm7GOBP_Double_Strand_Break_RepairMouseEmbryorep_2 4.2e-15
Mcm7GOBP_Chromosome_OrganizationMouseEmbryorep_3 1.4e-57
Mcm7GOBP_Dna_Conformation_ChangeMouseEmbryorep_3 1.5e-48
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseEmbryorep_4 1.2e-08
Mcm7GOBP_Response_To_Endogenous_StimulusMouseEmbryorep_6 2.0e-17
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyNep 4.6e-22
Mcm7GOBP_Response_To_Endogenous_StimulusMouseKidneyNep 6.3e-23
Mcm7GOBP_Cell_CycleMouseKidneyrep_2 1.0e-24
Mcm7GOBP_Cell_Cycle_Dna_ReplicationMouseKidneyrep_2 3.6e-23
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseKidneyrep_2 5.1e-80
Mcm7GOBP_Cell_Cycle_Phase_TransitionMouseKidneyrep_2 6.8e-67
Mcm7GOBP_Cell_Cycle_ProcessMouseKidneyrep_2 3.0e-21
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseKidneyrep_25.5e-146
Mcm7GOBP_Chromosome_OrganizationMouseKidneyrep_2 1.0e-14
Mcm7GOBP_Dna_Conformation_ChangeMouseKidneyrep_2 1.4e-38
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseKidneyrep_21.1e-109
Mcm7GOBP_Dna_Geometric_ChangeMouseKidneyrep_2 2.0e-24
Mcm7GOBP_Dna_Metabolic_ProcessMouseKidneyrep_2 1.4e-12
Mcm7GOBP_Dna_RecombinationMouseKidneyrep_2 2.7e-14
Mcm7GOBP_Dna_RepairMouseKidneyrep_2 5.5e-70
Mcm7GOBP_Dna_ReplicationMouseKidneyrep_2 5.9e-43
Mcm7GOBP_Dna_Replication_InitiationMouseKidneyrep_2 3.5e-30
Mcm7GOBP_Dna_Strand_ElongationMouseKidneyrep_2 2.0e-61
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseKidneyrep_2 2.3e-26
Mcm7GOBP_Double_Strand_Break_RepairMouseKidneyrep_2 1.5e-20
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseKidneyrep_2 3.5e-28
Mcm7GOBP_Mitotic_Cell_CycleMouseKidneyrep_2 1.1e-15
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseKidneyrep_2 1.1e-35
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyrep_2 1.3e-41
Mcm7GOBP_Response_To_Endogenous_StimulusMouseKidneyrep_2 1.1e-44
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseKidneyrep_2 5.3e-65
Mcm7GOBP_Response_To_Growth_FactorMouseKidneyrep_2 4.7e-31
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseKidneyrep_2 1.6e-88
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseLiverCN16-D2 8.1e-07
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseLiverCN16-D2 3.1e-08
Mcm7GOBP_Dna_Metabolic_ProcessMouseLiverCN16-D2 2.6e-07
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseLiverCN16-D2 2.4e-18
Mcm7GOBP_Dna_Replication_InitiationMouseLiverrep_15 9.0e-18
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseLiverrep_15 1.1e-13
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseLiverrep_15 7.8e-15
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseLiverrep_16 9.7e-19
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseIntestinerep_2 8.2e-20
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseIntestinerep_3 1.1e-13
Mcm7GOBP_Cell_CycleMouseLymphMS-1 1.3e-07
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseLymphMS-1 3.2e-07
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseLymphMS-1 8.5e-13
Mcm7GOBP_Chromosome_OrganizationMouseLymphMS-1 3.5e-09
Mcm7GOBP_Dna_Metabolic_ProcessMouseLymphMS-1 6.8e-10
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseLymphMS-1 2.3e-09
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseLymphMS-1 5.6e-12
Mcm7GOBP_Response_To_Endogenous_StimulusMouseLymphMS-1 3.9e-13
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseLymphMS-1 8.2e-11
Mcm7GOBP_Response_To_Growth_FactorMouseLymphMS-1 2.1e-10
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseLymphMS-1 1.8e-09
Mcm7GOBP_Cell_Cycle_Dna_ReplicationMouseLymphMS-2 7.1e-08
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseLymphMS-2 5.9e-08
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseLymphPBS 2.2e-07
Mcm7GOBP_Response_To_Endogenous_StimulusMouseLungrep_1 2.0e-30
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseBrainrep_4 1.9e-14
Mcm7GOBP_Double_Strand_Break_Repair_Via_Break_Induced_ReplicationMouseBrainHP_ad_rep3 1.5e-15
Mcm7GOBP_Cell_CycleMouseBrainHP_ad_rep7 6.6e-08
Mcm7GOBP_Cell_Cycle_Dna_ReplicationMouseBrainHP_ad_rep7 2.9e-18
Mcm7GOBP_Cell_Cycle_G1_S_Phase_TransitionMouseBrainHP_ad_rep7 3.5e-11
Mcm7GOBP_Cell_Cycle_Phase_TransitionMouseBrainHP_ad_rep7 4.9e-09
Mcm7GOBP_Cell_Cycle_ProcessMouseBrainHP_ad_rep7 1.7e-09
Mcm7GOBP_Cellular_Response_To_Dna_Damage_StimulusMouseBrainHP_ad_rep7 6.8e-10
Mcm7GOBP_Chromosome_OrganizationMouseBrainHP_ad_rep7 2.9e-10
Mcm7GOBP_Dna_Conformation_ChangeMouseBrainHP_ad_rep7 1.3e-13
Mcm7GOBP_Dna_Dependent_Dna_ReplicationMouseBrainHP_ad_rep7 1.6e-15
Mcm7GOBP_Dna_Geometric_ChangeMouseBrainHP_ad_rep7 1.0e-10
Mcm7GOBP_Dna_Metabolic_ProcessMouseBrainHP_ad_rep7 3.1e-11
Mcm7GOBP_Dna_RecombinationMouseBrainHP_ad_rep7 1.4e-08
Mcm7GOBP_Dna_RepairMouseBrainHP_ad_rep7 2.4e-12
Mcm7GOBP_Dna_ReplicationMouseBrainHP_ad_rep7 1.1e-10
Mcm7GOBP_Dna_Replication_InitiationMouseBrainHP_ad_rep7 2.9e-08
Mcm7GOBP_Dna_Strand_ElongationMouseBrainHP_ad_rep7 4.9e-11
Mcm7GOBP_Dna_Strand_Elongation_Involved_In_Dna_ReplicationMouseBrainHP_ad_rep7 3.6e-13
Mcm7GOBP_Dna_Unwinding_Involved_In_Dna_ReplicationMouseBrainHP_ad_rep7 7.2e-11
Mcm7GOBP_Double_Strand_Break_RepairMouseBrainHP_ad_rep7 2.7e-09
Mcm7GOBP_Protein_Dna_Complex_Subunit_OrganizationMouseBrainHP_ad_rep7 9.8e-13
Mcm7GOBP_Recombinational_RepairMouseBrainHP_ad_rep7 8.2e-08
Mcm7GOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainHP_ad_rep7 1.7e-08
Mcm7GOBP_Response_To_Endogenous_StimulusMouseBrainHP_ad_rep7 6.3e-10
Mcm7GOBP_Response_To_Growth_FactorMouseBrainHP_ad_rep7 3.5e-10
Mcm7GOBP_Response_To_Epidermal_Growth_FactorMouseBrainHP_adpolb_rep1 6.3e-08
Mcm7GOBP_Mitotic_Cell_CycleMouseBrainHP_polb_rep9 1.6e-10
Mcm7GOBP_Response_To_Xenobiotic_StimulusMouseBrainHP_polb_rep9 1.2e-10

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Mcm7 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Mcm7 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Mcm7 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Mcm7

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Mcm7

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource