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Spatial pattern gene: Mcm6 (spascer ID:17219) |
Gene summary for Mcm6 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Mcm6 | Gene ID | 17219 |
| Gene name | minichromosome maintenance complex component 6 |
| Synonyms | ASP-l1|D1Wsu22e|Mcmd6 |
| Cytomap | 1 E3|1 55.8 cM |
| Type of gene | protein-coding |
| Description | DNA replication licensing factor MCM6mini chromosome maintenance deficient 6minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) |
| Modification date | 20220424 |
| UniProtAcc | P97311 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Mcm6 | GO:0000727 | double-strand break repair via break-induced replication | 21873635 | Process |
| Mcm6 | GO:0003697 | single-stranded DNA binding | 21873635 | Function |
| Mcm6 | GO:0005634 | nucleus | 21873635 | Component |
| Mcm6 | GO:0006268 | DNA unwinding involved in DNA replication | 21873635 | Process |
| Mcm6 | GO:0017116 | single-stranded DNA helicase activity | 21873635 | Function |
| Mcm6 | GO:0042555 | MCM complex | 21873635 | Component |
| Mcm6 | GO:1902969 | mitotic DNA replication | 21873635 | Process |
| Mcm6 | GO:1990518 | single-stranded 3'-5' DNA helicase activity | 21873635 | Function |
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Spatial pattern events for Mcm6 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Mcm6 | Mouse | Brain | S2 | 34413515 | 1.75e-11 |
| Mcm6 | Mouse | Brain | S4 | 34413515 | 3.59e-08 |
| Mcm6 | Mouse | Brain | S6 | 34413515 | 2.05e-06 |
| Mcm6 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Mcm6 | Mouse | Brain | 27A | 32637622 | 1.01e-06 |
| Mcm6 | Mouse | Embryo | 2H | 34210887 | 4.35e-07 |
| Mcm6 | Mouse | Embryo | 3D | 34210887 | 8.57e-07 |
| Mcm6 | Mouse | Embryo | 3F | 34210887 | 1.00e-09 |
| Mcm6 | Mouse | Embryo | 4E | 34210887 | 6.48e-08 |
| Mcm6 | Mouse | Embryo | rep_2 | 33188776 | 3.90e-08 |
| Mcm6 | Mouse | Embryo | rep_4 | 33188776 | 1.05e-06 |
| Mcm6 | Mouse | Embryo | rep_12 | 33188776 | 5.95e-06 |
| Mcm6 | Mouse | Embryo | rep_13 | 33188776 | 3.18e-07 |
| Mcm6 | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Mcm6 | Mouse | Brain | rep_1 | 33469025 | 2.37e-15 |
| Mcm6 | Mouse | Intestine | rep_4 | 35149721 | 3.70e-13 |
| Mcm6 | Mouse | Testicle | rep_5 | 34731600 | 1.06e-09 |
| Mcm6 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Mcm6 | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Mcm6 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Mcm6 | Mouse | Lung | rep_2 | 35290801 | 1.64e-06 |
| Mcm6 | Mouse | Lung | rep_3 | 35290801 | 1.09e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
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Spatial pattern pathway has Mcm6 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Spinal cord | CN90_C1 | 3.8e-06 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 1.1e-06 |
| Mcm6 | GOBP_Cell_Cycle_Dna_Replication | Mouse | Spinal cord | CN94_E1 | 7.4e-07 |
| Mcm6 | GOBP_Cell_Cycle_Process | Mouse | Spinal cord | CN94_E1 | 3.8e-06 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Spinal cord | CN94_E1 | 8.0e-06 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Spinal cord | CN94_E1 | 2.7e-06 |
| Mcm6 | GOBP_Recombinational_Repair | Mouse | Spinal cord | CN94_E1 | 8.5e-06 |
| Mcm6 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Spinal cord | L7bCN02_E1 | 1.5e-06 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Spinal cord | L7bCN02_E1 | 3.4e-06 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Spinal cord | L7CN45_C1 | 6.7e-08 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Spinal cord | L7CN45_C1 | 3.4e-08 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Spinal cord | L7CN45_C1 | 8.1e-07 |
| Mcm6 | GOBP_Dna_Recombination | Mouse | Spinal cord | L7CN45_C1 | 5.6e-07 |
| Mcm6 | GOBP_Dna_Repair | Mouse | Spinal cord | L7CN45_C1 | 9.4e-06 |
| Mcm6 | GOBP_Dna_Replication | Mouse | Spinal cord | L7CN45_C1 | 2.8e-07 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Spinal cord | L7CN45_C1 | 6.9e-06 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Spinal cord | L7CN45_C1 | 5.4e-06 |
| Mcm6 | GOBP_Mitotic_Cell_Cycle | Mouse | Spinal cord | L7CN45_C1 | 2.4e-08 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Spinal cord | L7CN45_E1 | 9.7e-08 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Spinal cord | L7CN47_C1 | 6.6e-06 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Spinal cord | L7CN47_C1 | 2.6e-06 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Brain | rep_11 | 3.6e-05 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Brain | rep_11 | 2.1e-05 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Brain | rep_21 | 4.2e-05 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Brain | rep_27 | 8.4e-07 |
| Mcm6 | GOBP_Dna_Replication | Mouse | Brain | rep_27 | 6.4e-06 |
| Mcm6 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | rep_27 | 1.1e-05 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Brain | rep_1 | 7.0e-10 |
| Mcm6 | GOBP_Cell_Cycle_Dna_Replication | Mouse | Brain | rep_1 | 3.4e-08 |
| Mcm6 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Brain | rep_1 | 1.6e-31 |
| Mcm6 | GOBP_Cell_Cycle_Process | Mouse | Brain | rep_1 | 6.7e-14 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Brain | rep_1 | 3.9e-07 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Brain | rep_1 | 1.5e-17 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Brain | rep_1 | 1.1e-07 |
| Mcm6 | GOBP_Dna_Recombination | Mouse | Brain | rep_1 | 6.8e-13 |
| Mcm6 | GOBP_Dna_Replication | Mouse | Brain | rep_1 | 4.3e-10 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Brain | rep_1 | 1.9e-10 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Brain | rep_1 | 5.6e-13 |
| Mcm6 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | rep_1 | 1.5e-25 |
| Mcm6 | GOBP_Recombinational_Repair | Mouse | Brain | rep_1 | 5.8e-08 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Brain | rep_3 | 3.0e-140 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Brain | rep_3 | 5.0e-192 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Brain | rep_3 | 7.4e-54 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Brain | rep_3 | 4.9e-189 |
| Mcm6 | GOBP_Dna_Repair | Mouse | Brain | rep_3 | 4.0e-216 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Brain | rep_3 | 7.8e-86 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Brain | rep_3 | 3.5e-61 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Brain | rep_3 | 5.3e-122 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Brain | rep_5 | 5.3e-09 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Embryo | rep_14 | 2.1e-08 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Embryo | rep_14 | 5.1e-11 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Embryo | rep_14 | 3.1e-28 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Embryo | rep_14 | 1.0e-37 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Embryo | rep_14 | 1.4e-07 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Embryo | rep_14 | 1.6e-37 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Embryo | rep_14 | 2.5e-26 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Embryo | rep_14 | 2.2e-11 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Embryo | rep_2 | 1.4e-08 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Embryo | rep_2 | 7.2e-216 |
| Mcm6 | GOBP_Dna_Recombination | Mouse | Embryo | rep_2 | 0.0e+00 |
| Mcm6 | GOBP_Dna_Repair | Mouse | Embryo | rep_2 | 1.6e-282 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Embryo | rep_2 | 4.2e-15 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Embryo | rep_3 | 1.4e-57 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Embryo | rep_3 | 1.5e-48 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Embryo | rep_4 | 1.2e-08 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Kidney | rep_2 | 1.0e-24 |
| Mcm6 | GOBP_Cell_Cycle_Dna_Replication | Mouse | Kidney | rep_2 | 3.6e-23 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Kidney | rep_2 | 5.1e-80 |
| Mcm6 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Kidney | rep_2 | 6.8e-67 |
| Mcm6 | GOBP_Cell_Cycle_Process | Mouse | Kidney | rep_2 | 3.0e-21 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Kidney | rep_2 | 5.5e-146 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Kidney | rep_2 | 1.0e-14 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Kidney | rep_2 | 1.4e-38 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Kidney | rep_2 | 1.1e-109 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Kidney | rep_2 | 2.0e-24 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Kidney | rep_2 | 1.4e-12 |
| Mcm6 | GOBP_Dna_Recombination | Mouse | Kidney | rep_2 | 2.7e-14 |
| Mcm6 | GOBP_Dna_Repair | Mouse | Kidney | rep_2 | 5.5e-70 |
| Mcm6 | GOBP_Dna_Replication | Mouse | Kidney | rep_2 | 5.9e-43 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Kidney | rep_2 | 3.5e-30 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Kidney | rep_2 | 1.5e-20 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Kidney | rep_2 | 3.5e-28 |
| Mcm6 | GOBP_Mitotic_Cell_Cycle | Mouse | Kidney | rep_2 | 1.1e-15 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Kidney | rep_2 | 2.1e-53 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Kidney | rep_2 | 1.1e-35 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Liver | CN16-D2 | 8.1e-07 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Liver | CN16-D2 | 3.1e-08 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Liver | CN16-D2 | 2.6e-07 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Liver | CN73-C1 | 4.1e-07 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Liver | rep_15 | 9.0e-18 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Liver | rep_15 | 7.8e-15 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Intestine | rep_3 | 1.1e-13 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Lymph | MS-1 | 1.3e-07 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Lymph | MS-1 | 3.2e-07 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Lymph | MS-1 | 8.5e-13 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Lymph | MS-1 | 3.5e-09 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Lymph | MS-1 | 6.8e-10 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Lymph | MS-1 | 2.3e-09 |
| Mcm6 | GOBP_Cell_Cycle_Dna_Replication | Mouse | Lymph | MS-2 | 7.1e-08 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Lymph | MS-2 | 5.9e-08 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Lymph | PBS | 2.2e-07 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Lung | rep_1 | 4.6e-11 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Brain | rep_4 | 1.9e-14 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Brain | rep_7 | 4.8e-18 |
| Mcm6 | GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication | Mouse | Brain | HP_ad_rep3 | 1.5e-15 |
| Mcm6 | GOBP_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 6.6e-08 |
| Mcm6 | GOBP_Cell_Cycle_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 2.9e-18 |
| Mcm6 | GOBP_Cell_Cycle_G1_S_Phase_Transition | Mouse | Brain | HP_ad_rep7 | 3.5e-11 |
| Mcm6 | GOBP_Cell_Cycle_Phase_Transition | Mouse | Brain | HP_ad_rep7 | 4.9e-09 |
| Mcm6 | GOBP_Cell_Cycle_Process | Mouse | Brain | HP_ad_rep7 | 1.7e-09 |
| Mcm6 | GOBP_Cellular_Response_To_Dna_Damage_Stimulus | Mouse | Brain | HP_ad_rep7 | 6.8e-10 |
| Mcm6 | GOBP_Chromosome_Organization | Mouse | Brain | HP_ad_rep7 | 2.9e-10 |
| Mcm6 | GOBP_Dna_Conformation_Change | Mouse | Brain | HP_ad_rep7 | 1.3e-13 |
| Mcm6 | GOBP_Dna_Dependent_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 1.6e-15 |
| Mcm6 | GOBP_Dna_Geometric_Change | Mouse | Brain | HP_ad_rep7 | 1.0e-10 |
| Mcm6 | GOBP_Dna_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 3.1e-11 |
| Mcm6 | GOBP_Dna_Recombination | Mouse | Brain | HP_ad_rep7 | 1.4e-08 |
| Mcm6 | GOBP_Dna_Repair | Mouse | Brain | HP_ad_rep7 | 2.4e-12 |
| Mcm6 | GOBP_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 1.1e-10 |
| Mcm6 | GOBP_Dna_Replication_Initiation | Mouse | Brain | HP_ad_rep7 | 2.9e-08 |
| Mcm6 | GOBP_Dna_Unwinding_Involved_In_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 7.2e-11 |
| Mcm6 | GOBP_Double_Strand_Break_Repair | Mouse | Brain | HP_ad_rep7 | 2.7e-09 |
| Mcm6 | GOBP_Mitotic_Dna_Replication | Mouse | Brain | HP_ad_rep7 | 3.5e-16 |
| Mcm6 | GOBP_Protein_Dna_Complex_Subunit_Organization | Mouse | Brain | HP_ad_rep7 | 9.8e-13 |
| Mcm6 | GOBP_Recombinational_Repair | Mouse | Brain | HP_ad_rep7 | 8.2e-08 |
| Mcm6 | GOBP_Mitotic_Cell_Cycle | Mouse | Brain | HP_polb_rep9 | 1.6e-10 |
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Mcm6 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |