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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Man1a2 (spascer ID:17156)

Gene summary for Man1a2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Man1a2
	Gene ID	17156
	Gene name	mannosidase, alpha, class 1A, member 2
	Synonyms	AI428775\|AI528764\|AI854422\|Man1b\|PCR2
	Cytomap	3\|3 F2.2
	Type of gene	protein-coding
	Description	mannosyl-oligosaccharide 1,2-alpha-mannosidase IBalpha-1,2-mannosidase IBmannosidase 1, betaprocessing alpha-1,2-mannosidase IB
	Modification date	20220424
	UniProtAcc	P39098

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Man1a2	GO:0000139	Golgi membrane	21873635	Component
Man1a2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	21873635	Function
Man1a2	GO:0005783	endoplasmic reticulum	21873635	Component
Man1a2	GO:0006491	N-glycan processing	21873635	Process

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Spatial pattern events for Man1a2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Man1a2	Mouse	Brain	S1	34413515	7.10e-15
Man1a2	Mouse	Brain	S2	34413515	1.56e-15
Man1a2	Mouse	Brain	S3	34413515	2.96e-15
Man1a2	Mouse	Brain	S4	34413515	1.37e-15
Man1a2	Mouse	Brain	S6	34413515	1.46e-15
Man1a2	Mouse	Brain	S7	34413515	1.55e-15
Man1a2	Mouse	Brain	rep_1	35141374	3.58e-15
Man1a2	Mouse	Brain	rep_2	35141374	5.60e-14
Man1a2	Mouse	Brain	rep_3	35141374	1.64e-15
Man1a2	Mouse	Brain	rep_4	35141374	1.57e-15
Man1a2	Mouse	Brain	rep_5	35141374	1.47e-15
Man1a2	Mouse	Brain	rep_6	35141374	5.33e-09
Man1a2	Mouse	Kidney	CLP	34003797	6.51e-06
Man1a2	Mouse	Brain	rep_1	33469025	1.02e-09
Man1a2	Mouse	Brain	rep_1	35027729	5.48e-14
Man1a2	Mouse	Brain	rep_2	35027729	5.40e-15
Man1a2	Mouse	Brain	rep_3	35027729	4.57e-15
Man1a2	Mouse	Brain	rep_4	35027729	3.10e-15
Man1a2	Mouse	Brain	rep_5	35027729	1.46e-15
Man1a2	Mouse	Intestine	rep_2	35149721	9.52e-13
Man1a2	Mouse	Testicle	rep_5	34731600	1.37e-14
Man1a2	Mouse	Lymph	A1	0	1.40e-10
Man1a2	Mouse	Lymph	B1	0	4.31e-14
Man1a2	Mouse	Lung	rep_1	35290801	1.56e-10
Man1a2	Mouse	Brain	rep_1	35210624	1.31e-06
Man1a2	Mouse	Brain	rep_2	35210624	1.24e-09
Man1a2	Mouse	Brain	rep_5	35210624	4.15e-09
Man1a2	Mouse	Brain	rep_7	35210624	1.89e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E

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Spatial pattern pathway has Man1a2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-06
Man1a2	GOBP_Respiratory_System_Development	Mouse	Spinal cord	CN94_E1	6.9e-08
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Spinal cord	L7bCN01_D2	9.0e-06
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Spinal cord	L7bCN02_E1	6.0e-08
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-08
Man1a2	GOBP_Glycosylation	Mouse	Spinal cord	L7CN45_C1	8.2e-08
Man1a2	GOBP_N_Glycan_Processing	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Spinal cord	L7CN45_C1	5.7e-06
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Spinal cord	L7CN45_C1	9.5e-06
Man1a2	GOBP_Tube_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Brain	rep_41	2.2e-09
Man1a2	GOBP_Protein_Demannosylation	Mouse	Brain	rep_41	2.6e-06
Man1a2	GOBP_Protein_Demannosylation	Mouse	Brain	rep_1	1.1e-12
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Brain	rep_1	1.7e-11
Man1a2	GOBP_Respiratory_System_Development	Mouse	Brain	rep_1	8.4e-12
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	rep_3	2.7e-27
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	rep_3	1.4e-74
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	6.4e-155
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	rep_3	1.9e-173
Man1a2	GOBP_Glycosylation	Mouse	Brain	rep_3	1.2e-150
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Brain	rep_3	3.0e-104
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Brain	rep_3	8.2e-113
Man1a2	GOBP_Tube_Development	Mouse	Brain	rep_3	9.0e-136
Man1a2	GOBP_N_Glycan_Processing	Mouse	Brain	rep_5	2.4e-07
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Embryo	rep_6	7.9e-07
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Embryo	rep_14	4.5e-09
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-08
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Embryo	rep_14	1.1e-10
Man1a2	GOBP_N_Glycan_Processing	Mouse	Embryo	rep_14	1.4e-28
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Embryo	rep_14	2.7e-54
Man1a2	GOBP_Protein_Demannosylation	Mouse	Embryo	rep_14	2.3e-26
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_1	5.6e-24
Man1a2	GOBP_Respiratory_System_Development	Mouse	Embryo	rep_1	3.5e-10
Man1a2	GOBP_Glycosylation	Mouse	Embryo	rep_3	2.6e-64
Man1a2	GOBP_Tube_Development	Mouse	Kidney	Nep	5.6e-37
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Kidney	rep_2	1.3e-08
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Kidney	rep_2	5.2e-99
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	2.5e-89
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-102
Man1a2	GOBP_Glycosylation	Mouse	Kidney	rep_2	5.3e-81
Man1a2	GOBP_N_Glycan_Processing	Mouse	Kidney	rep_2	9.6e-107
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Kidney	rep_2	5.1e-59
Man1a2	GOBP_Protein_Demannosylation	Mouse	Kidney	rep_2	5.4e-54
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Kidney	rep_2	2.1e-54
Man1a2	GOBP_Respiratory_System_Development	Mouse	Kidney	rep_2	2.1e-43
Man1a2	GOBP_Tube_Development	Mouse	Kidney	rep_2	1.2e-129
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.2e-07
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Liver	CN73-C1	9.7e-08
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-07
Man1a2	GOBP_Glycosylation	Mouse	Liver	CN73-C1	2.0e-07
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Liver	rep_15	5.5e-07
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	rep_16	2.6e-08
Man1a2	GOBP_N_Glycan_Processing	Mouse	Liver	rep_16	2.8e-17
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Lymph	MS-1	5.9e-10
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	4.4e-07
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-07
Man1a2	GOBP_Glycosylation	Mouse	Lymph	MS-1	4.8e-08
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Lymph	MS-1	4.7e-09
Man1a2	GOBP_N_Glycan_Processing	Mouse	Lymph	MS-1	9.4e-08
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Lymph	MS-1	1.4e-11
Man1a2	GOBP_Protein_Demannosylation	Mouse	Lymph	MS-1	2.8e-10
Man1a2	GOBP_Respiratory_System_Development	Mouse	Lymph	MS-1	3.8e-07
Man1a2	GOBP_Tube_Development	Mouse	Lymph	MS-1	4.6e-09
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Brain	rep_4	3.3e-72
Man1a2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	9.8e-07
Man1a2	GOBP_Glycosylation	Mouse	Brain	HP_ad_rep7	3.3e-08
Man1a2	GOBP_Lung_Alveolus_Development	Mouse	Brain	HP_ad_rep7	1.1e-10
Man1a2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Man1a2	GOBP_Tube_Development	Mouse	Brain	HP_ad_rep7	2.0e-08
Man1a2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	2.0e-07
Man1a2	GOBP_N_Glycan_Processing	Mouse	Brain	HP_adpolb_rep1	3.3e-07
Man1a2	GOBP_Protein_Demannosylation	Mouse	Brain	HP_adpolb_rep3	1.0e-07
Man1a2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Man1a2	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-09
Man1a2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.4e-10
Man1a2	GOBP_Protein_Deglycosylation	Mouse	Brain	HP_polb_rep9	2.1e-21
Man1a2	GOBP_Respiratory_Gaseous_Exchange_By_Respiratory_System	Mouse	Brain	HP_polb_rep9	2.5e-09
Man1a2	GOBP_Respiratory_System_Development	Mouse	Brain	HP_polb_rep9	3.6e-07

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Man1a2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Man1a2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Man1a2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Man1a2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Man1a2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source