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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mfap2 (spascer ID:17150)

Gene summary for Mfap2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mfap2
	Gene ID	17150
	Gene name	microfibrillar-associated protein 2
	Synonyms	AI893631\|Magp\|Magp1
	Cytomap	4\|4 D3
	Type of gene	protein-coding
	Description	microfibrillar-associated protein 2MAGP-1MFAP-2microfibril-associated glycoprotein 1microfibril-associated glycoprotein 1Amicrofibril-associated glycoprotein 1D
	Modification date	20220424
	UniProtAcc	P55002

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mfap2	GO:0001527	microfibril	21873635	Component
Mfap2	GO:0048048	embryonic eye morphogenesis	21873635	Process

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Spatial pattern events for Mfap2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mfap2	Mouse	Brain	S4	34413515	6.42e-08
Mfap2	Mouse	Brain	S6	34413515	5.38e-08
Mfap2	Mouse	Embryo	1D	34210887	1.46e-14
Mfap2	Mouse	Embryo	1E	34210887	2.33e-06
Mfap2	Mouse	Embryo	1F	34210887	2.25e-12
Mfap2	Mouse	Embryo	1G	34210887	1.19e-13
Mfap2	Mouse	Embryo	2G	34210887	4.26e-12
Mfap2	Mouse	Embryo	2H	34210887	9.15e-15
Mfap2	Mouse	Embryo	3D	34210887	4.55e-10
Mfap2	Mouse	Embryo	3F	34210887	1.33e-13
Mfap2	Mouse	Embryo	3G	34210887	1.23e-12
Mfap2	Mouse	Embryo	3H	34210887	1.39e-06
Mfap2	Mouse	Embryo	4D	34210887	7.86e-10
Mfap2	Mouse	Embryo	4E	34210887	4.53e-15
Mfap2	Mouse	Embryo	rep_1	33188776	1.88e-13
Mfap2	Mouse	Embryo	rep_2	33188776	1.37e-14
Mfap2	Mouse	Embryo	rep_4	33188776	8.29e-15
Mfap2	Mouse	Embryo	rep_12	33188776	4.84e-15
Mfap2	Mouse	Embryo	rep_13	33188776	4.49e-15
Mfap2	Mouse	Embryo	rep_14	33188776	4.05e-14
Mfap2	Mouse	Embryo	rep_15	33188776	1.58e-09
Mfap2	Mouse	Kidney	rep_1	34853151	2.42e-15
Mfap2	Mouse	Kidney	rep_5	34853151	3.18e-15
Mfap2	Mouse	Kidney	rep_1	33976190	1.19e-06
Mfap2	Mouse	Brain	rep_1	33469025	1.30e-15
Mfap2	Mouse	Testicle	rep_6	34731600	5.92e-08
Mfap2	Mouse	Lung	rep_1	35290801	1.21e-14
Mfap2	Mouse	Lung	rep_2	35290801	2.22e-06
Mfap2	Mouse	Lung	rep_4	35290801	3.04e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_1_H&E
Kidney_rep_5_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Mfap2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	7.7e-07
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Spinal cord	CN94_E1	1.2e-06
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Spinal cord	CN94_E1	4.5e-06
Mfap2	GOBP_Eye_Morphogenesis	Mouse	Spinal cord	L7bCN02_E1	4.0e-07
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Spinal cord	L7CN45_C1	4.5e-09
Mfap2	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mfap2	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Mfap2	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Spinal cord	L7CN45_C1	3.5e-09
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Spinal cord	L7CN45_C1	2.1e-06
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Mfap2	GOBP_Sensory_System_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Spinal cord	L7CN45_C1	8.7e-08
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Spinal cord	L7CN45_D1	2.0e-07
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Spinal cord	L7CN45_D1	1.5e-06
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Spinal cord	L7CN45_E1	6.2e-11
Mfap2	GOBP_Embryonic_Eye_Morphogenesis	Mouse	Spinal cord	L7CN75_C1	8.6e-06
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Spinal cord	L7CN97_E2	6.4e-07
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Brain	rep_21	1.7e-06
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_27	8.3e-05
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Brain	rep_27	4.5e-07
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_27	4.9e-05
Mfap2	GOBP_Sensory_System_Development	Mouse	Brain	rep_27	1.2e-05
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Brain	rep_41	5.7e-06
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_71	2.6e-07
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Brain	rep_1	2.2e-14
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Brain	rep_1	1.4e-15
Mfap2	GOBP_Sensory_System_Development	Mouse	Brain	rep_1	1.6e-12
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Mfap2	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Mfap2	GOBP_Embryonic_Eye_Morphogenesis	Mouse	Brain	rep_3	3.0e-50
Mfap2	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_3	4.3e-190
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-168
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	rep_3	8.9e-180
Mfap2	GOBP_Eye_Morphogenesis	Mouse	Brain	rep_3	4.2e-134
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	rep_3	6.7e-70
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_3	3.5e-105
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Brain	rep_3	1.1e-69
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Brain	rep_3	5.2e-204
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_3	1.6e-123
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-133
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Brain	rep_4	9.5e-07
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Brain	rep_7	2.9e-65
Mfap2	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Embryo	rep_14	2.8e-18
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Embryo	rep_14	2.2e-13
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Embryo	rep_14	1.4e-13
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Embryo	rep_14	6.8e-41
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Embryo	rep_14	1.6e-19
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_14	3.5e-27
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Embryo	rep_14	6.5e-07
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Embryo	rep_14	1.3e-46
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_14	7.1e-17
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Embryo	rep_14	4.5e-07
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Embryo	rep_1	0.0e+00
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Mfap2	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Embryo	rep_1	7.9e-50
Mfap2	GOBP_Sensory_System_Development	Mouse	Embryo	rep_1	1.3e-72
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Embryo	rep_1	0.0e+00
Mfap2	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Embryo	rep_3	0.0e+00
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Embryo	rep_3	1.4e-22
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_3	1.4e-22
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Embryo	rep_3	1.4e-22
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Embryo	rep_3	2.1e-266
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_3	9.1e-62
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Embryo	rep_6	1.1e-18
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Embryo	rep_6	1.5e-08
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	Nep	1.8e-38
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Kidney	Sham	2.7e-10
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Kidney	Sham	7.4e-36
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Kidney	rep_2	2.9e-21
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Mfap2	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Mfap2	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Kidney	rep_2	1.3e-60
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.0e-55
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Kidney	rep_2	5.6e-85
Mfap2	GOBP_Eye_Morphogenesis	Mouse	Kidney	rep_2	1.2e-85
Mfap2	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Kidney	rep_2	1.3e-51
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Kidney	rep_2	3.1e-07
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	rep_2	2.7e-43
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Kidney	rep_2	2.7e-32
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Kidney	rep_2	6.6e-26
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	2.3e-30
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Kidney	rep_2	9.0e-20
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Kidney	rep_2	9.6e-31
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Kidney	rep_2	4.7e-27
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.2e-88
Mfap2	GOBP_Sensory_System_Development	Mouse	Kidney	rep_2	7.2e-08
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Kidney	rep_2	4.5e-41
Mfap2	GOBP_Embryonic_Eye_Morphogenesis	Mouse	Liver	CN16-D2	8.2e-07
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Liver	CN16-D2	4.7e-08
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Liver	CN16-D2	9.2e-07
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Liver	CN16-E1	3.4e-16
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Liver	CN73-C1	1.4e-08
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	CN73-C1	5.5e-08
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Liver	rep_15	7.9e-07
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Liver	rep_15	2.7e-09
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Liver	rep_16	4.4e-20
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Liver	rep_16	1.6e-15
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Liver	rep_16	6.6e-12
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Liver	rep_16	9.3e-17
Mfap2	GOBP_Embryonic_Eye_Morphogenesis	Mouse	Liver	rep_17	5.0e-11
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Lymph	MS-1	1.1e-14
Mfap2	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Mfap2	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Mfap2	GOBP_Embryonic_Eye_Morphogenesis	Mouse	Lymph	MS-1	3.5e-11
Mfap2	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Lymph	MS-1	1.1e-11
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Lymph	MS-1	1.4e-11
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lymph	MS-1	6.5e-12
Mfap2	GOBP_Eye_Morphogenesis	Mouse	Lymph	MS-1	1.6e-09
Mfap2	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Lymph	MS-1	1.1e-12
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Lymph	MS-1	4.7e-12
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lymph	MS-1	1.4e-15
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Lymph	MS-1	5.0e-11
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Lymph	MS-1	1.9e-13
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Lymph	MS-1	1.5e-10
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Lymph	MS-1	3.6e-12
Mfap2	GOBP_Sensory_System_Development	Mouse	Lymph	MS-1	1.2e-07
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Lymph	MS-1	9.0e-11
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lung	rep_1	1.3e-11
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Lung	rep_1	2.1e-24
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Lung	rep_1	8.0e-09
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Lung	rep_1	1.9e-10
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Lung	rep_1	2.2e-16
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Brain	rep_4	2.4e-14
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Brain	rep_4	6.6e-13
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Brain	rep_4	5.6e-20
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_7	7.0e-07
Mfap2	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_7	2.6e-14
Mfap2	GOBP_Post_Embryonic_Animal_Morphogenesis	Mouse	Brain	HP_ad_rep3	4.9e-10
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Morphogenesis	Mouse	Brain	HP_ad_rep3	5.2e-07
Mfap2	GOBP_Post_Embryonic_Eye_Morphogenesis	Mouse	Brain	HP_ad_rep3	1.5e-17
Mfap2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	HP_ad_rep7	1.9e-11
Mfap2	GOBP_Eye_Morphogenesis	Mouse	Brain	HP_ad_rep7	4.2e-07
Mfap2	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	HP_ad_rep7	9.1e-08
Mfap2	GOBP_Post_Embryonic_Development	Mouse	Brain	HP_ad_rep7	2.8e-15
Mfap2	GOBP_Sensory_Organ_Development	Mouse	Brain	HP_ad_rep7	4.6e-10
Mfap2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	HP_ad_rep7	9.0e-08
Mfap2	GOBP_Sensory_System_Development	Mouse	Brain	HP_ad_rep7	1.6e-11
Mfap2	GOBP_Adaptive_Thermogenesis	Mouse	Brain	HP_adpolb_rep1	4.2e-07
Mfap2	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Mfap2	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Mfap2	GOBP_Embryonic_Organ_Development	Mouse	Brain	HP_polb_rep9	9.6e-11
Mfap2	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Mfap2	GOBP_Multicellular_Organismal_Homeostasis	Mouse	Brain	HP_polb_rep9	3.2e-07
Mfap2	GOBP_Positive_Regulation_Of_Cold_Induced_Thermogenesis	Mouse	Brain	HP_polb_rep9	3.4e-10
Mfap2	GOBP_Post_Embryonic_Animal_Organ_Development	Mouse	Brain	HP_polb_rep9	3.7e-08
Mfap2	GOBP_Temperature_Homeostasis	Mouse	Brain	HP_polb_rep9	3.7e-12

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Mfap2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mfap2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
Mfap2	Notch1	Mfap2_Notch1	Kidney	rep_1

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Transcription factor for Mfap2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mfap2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mfap2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source