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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Marcks (spascer ID:17118)

Gene summary for Marcks

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Marcks

Gene ID

17118

Gene namemyristoylated alanine rich protein kinase C substrate
SynonymsMacs|PKCSL
Cytomap10 B1|10 19.49 cM
Type of geneprotein-coding
Descriptionmyristoylated alanine-rich C-kinase substrate80K protein
Modification date20220424
UniProtAcc

P26645


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Marcks

GO:0005737

cytoplasm

21873635

Component
Marcks

GO:0005886

plasma membrane

21873635

Component
Marcks

GO:0007015

actin filament organization

21873635

Process
Marcks

GO:0007417

central nervous system development

21873635

Process
Marcks

GO:0032432

actin filament bundle

21873635

Component
Marcks

GO:0051015

actin filament binding

21873635

Function

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Spatial pattern events for Marcks

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
MarcksMouseSpinal cordL7bCN03_C2 309485521.49e-06
MarcksMouseBrainS1 344135152.07e-15
MarcksMouseBrainS2 344135151.56e-15
MarcksMouseBrainS3 344135151.64e-15
MarcksMouseBrainS4 344135151.37e-15
MarcksMouseBrainS6 344135151.46e-15
MarcksMouseBrainS7 344135151.55e-15
MarcksMouseBrain04B 326376224.34e-06
MarcksMouseBrain05A 326376225.52e-09
MarcksMouseBrain05B 326376222.80e-14
MarcksMouseBrain06A 326376225.54e-12
MarcksMouseBrain06B 326376221.68e-14
MarcksMouseBrain07A 326376222.11e-13
MarcksMouseBrain07B 326376225.43e-14
MarcksMouseBrain08A 326376222.81e-12
MarcksMouseBrain08B 326376221.34e-09
MarcksMouseBrain09A 326376225.97e-09
MarcksMouseBrain09B 326376221.55e-08
MarcksMouseBrain11A 326376223.10e-11
MarcksMouseBrain12B 326376221.20e-14
MarcksMouseBrain13B 326376221.94e-07
MarcksMouseBrain14A 326376222.80e-11
MarcksMouseBrain14B 326376222.16e-14
MarcksMouseBrain15A 326376229.41e-09
MarcksMouseBrain16A 326376222.16e-09
MarcksMouseBrain16B 326376222.12e-13
MarcksMouseBrain17A 326376223.71e-14
MarcksMouseBrain17B 326376224.11e-14
MarcksMouseBrain18A 326376221.20e-14
MarcksMouseBrain18B 326376221.38e-14
MarcksMouseBrain19A 326376221.35e-14
MarcksMouseBrain19B 326376221.36e-14
MarcksMouseBrain20A 326376222.42e-14
MarcksMouseBrain20B 326376221.93e-11
MarcksMouseBrain21A 326376221.43e-14
MarcksMouseBrain21B 326376221.37e-14
MarcksMouseBrain22A 326376228.87e-15
MarcksMouseBrain22B 326376228.81e-15
MarcksMouseBrain23A 326376221.72e-14
MarcksMouseBrain23B 326376221.10e-14
MarcksMouseBrain24A 326376221.61e-14
MarcksMouseBrain24B 326376221.40e-14
MarcksMouseBrain25A 326376221.86e-14
MarcksMouseBrain26A 326376225.92e-10
MarcksMouseBrain27A 326376221.11e-08
MarcksMouseBrain27B 326376222.26e-07
MarcksMouseBrain28A 326376221.59e-06
MarcksMouseBrain28B 326376224.76e-08
MarcksMouseBrain29A 326376228.29e-08
MarcksMouseBrain29B 326376229.01e-07
MarcksMouseBrain30A 326376229.74e-07
MarcksMouseBrain31A 326376224.88e-14
MarcksMouseBrain32A 326376222.12e-08
MarcksMouseBrain33A 326376223.13e-10
MarcksMouseBrain33B 326376222.57e-07
MarcksMouseBrain34A 326376221.42e-14
MarcksMouseBrain35A 326376225.00e-08
MarcksMouseBrain35B 326376227.71e-06
MarcksMouseBrain36A 326376224.66e-12
MarcksMouseBrain36B 326376228.27e-14
MarcksMouseBrain37A 326376229.65e-12
MarcksMouseBrain37B 326376222.45e-09
MarcksMouseBrain38A 326376221.38e-09
MarcksMouseBrain38B 326376223.51e-12
MarcksMouseBrain39A 326376225.28e-12
MarcksMouseBrain40B 326376221.64e-08
MarcksMouseBrainrep_1 351413742.02e-15
MarcksMouseBrainrep_2 351413741.69e-15
MarcksMouseBrainrep_3 351413741.64e-15
MarcksMouseBrainrep_4 351413741.57e-15
MarcksMouseBrainrep_5 351413741.47e-15
MarcksMouseBrainrep_6 351413741.73e-15
MarcksMouseEmbryo1E 342108872.01e-06
MarcksMouseEmbryo1G 342108875.04e-13
MarcksMouseEmbryo2H 342108875.31e-15
MarcksMouseEmbryo3D 342108878.93e-15
MarcksMouseEmbryo3F 342108875.82e-15
MarcksMouseEmbryo3G 342108875.66e-14
MarcksMouseEmbryo4C 342108871.06e-12
MarcksMouseEmbryo4D 342108871.36e-14
MarcksMouseEmbryo4E 342108874.53e-15
MarcksMouseEmbryorep_1 331887769.94e-15
MarcksMouseEmbryorep_2 331887761.37e-14
MarcksMouseEmbryorep_3 331887761.13e-14
MarcksMouseEmbryorep_4 331887765.08e-15
MarcksMouseEmbryorep_5 331887761.40e-14
MarcksMouseEmbryorep_6 331887762.20e-14
MarcksMouseEmbryorep_7 331887766.94e-15
MarcksMouseEmbryorep_12 331887764.84e-15
MarcksMouseEmbryorep_13 331887764.49e-15
MarcksMouseEmbryorep_14 331887761.20e-14
MarcksMouseEmbryorep_15 331887765.97e-15
MarcksMouseEmbryorep_1 344896003.74e-16
MarcksMouseEmbryorep_2 344896004.14e-16
MarcksMouseEmbryorep_3 344896004.04e-16
MarcksMouseEmbryorep_4 344896003.67e-16
MarcksMouseEmbryorep_5 344896004.08e-16
MarcksMouseEmbryorep_6 344896007.05e-16
MarcksMouseKidneyCLP 340037972.19e-15
MarcksMouseKidneyIRI 340037972.29e-15
MarcksMouseKidneySham 340037974.30e-15
MarcksMouseKidneyrep_1 348531512.42e-15
MarcksMouseKidneyrep_2 348531511.39e-07
MarcksMouseKidneyrep_4 348531514.07e-15
MarcksMouseKidneyrep_5 348531513.18e-15
MarcksMouseKidneyrep_1 339761905.08e-07
MarcksMouseKidneyrep_2 339761905.05e-09
MarcksMouseBrainrep_1 334690251.30e-15
MarcksMouseLiverrep_20 350210631.65e-14
MarcksMouseBrainrep_1 350277291.66e-15
MarcksMouseBrainrep_2 350277291.57e-15
MarcksMouseBrainrep_3 350277291.32e-15
MarcksMouseBrainrep_4 350277291.76e-15
MarcksMouseBrainrep_5 350277291.46e-15
MarcksMouseIntestinerep_1 351497215.28e-10
MarcksMouseIntestinerep_2 351497213.44e-15
MarcksMouseIntestinerep_3 351497215.21e-15
MarcksMouseIntestinerep_4 351497211.54e-10
MarcksMouseBrainB02_D1 327023141.50e-14
MarcksMouseBrainB02_E1 327023141.33e-14
MarcksMouseBrainB03_C2 327023145.51e-14
MarcksMouseBrainB03_D2 327023142.13e-14
MarcksMouseBrainB04_D1 327023144.37e-13
MarcksMouseBrainB04_E1 327023141.82e-06
MarcksMouseBrainB05_E2 327023144.32e-07
MarcksMouseBrainB06_E1 327023148.89e-09
MarcksMouseBrainN02_C1 327023143.13e-14
MarcksMouseBrainN02_D1 327023142.44e-14
MarcksMouseBrainN03_C2 327023142.55e-14
MarcksMouseBrainN03_D2 327023142.33e-14
MarcksMouseBrainN04_D1 327023144.74e-13
MarcksMouseBrainN04_E1 327023141.45e-12
MarcksMouseBrainN05_C2 327023145.73e-14
MarcksMouseBrainN05_D2 327023141.93e-14
MarcksMouseLymphA1 03.29e-15
MarcksMouseLymphB1 03.66e-15
MarcksMouseLungrep_1 352908016.56e-15
MarcksMouseLungrep_2 352908011.42e-14
MarcksMouseLungrep_3 352908015.95e-14
MarcksMouseLungrep_4 352908012.24e-10
MarcksMouseBrainrep_1 352106241.74e-15
MarcksMouseBrainrep_2 352106241.74e-15
MarcksMouseBrainrep_3 352106241.82e-15
MarcksMouseBrainrep_4 352106242.34e-15
MarcksMouseBrainrep_5 352106242.07e-15
MarcksMouseBrainrep_6 352106242.05e-15
MarcksMouseBrainrep_7 352106241.87e-15
MarcksMouseBrainOFB_ad_rep4 330837253.83e-05
MarcksMouseBrainOFB_adpolb_rep4 330837251.35e-02
MarcksMouseBrainOFB_polb_rep5 330837251.95e-02
MarcksMouseBrainOFB_wt_rep5 330837255.44e-04

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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Kidney_rep_2_H&E
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Kidney_rep_4_H&E
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Kidney_rep_5_H&E
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Kidney_rep_1_H&E
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Kidney_rep_2_H&E
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Brain_rep_1_H&E
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Liver_rep_20_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_D1_H&E
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Brain_B02_E1_H&E
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Brain_B03_C2_H&E
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Brain_B03_D2_H&E
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Brain_B04_D1_H&E
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Brain_B04_E1_H&E
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Brain_B05_E2_H&E
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Brain_B06_E1_H&E
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Brain_N02_C1_H&E
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Brain_N02_D1_H&E
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Brain_N03_C2_H&E
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Brain_N03_D2_H&E
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Brain_N04_D1_H&E
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Brain_N04_E1_H&E
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Brain_N05_C2_H&E
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Brain_N05_D2_H&E
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Lung_rep_1_H&E
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Lung_rep_2_H&E
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Lung_rep_3_H&E
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Lung_rep_4_H&E
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Brain_OFB_ad_rep4_H&E
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Brain_OFB_adpolb_rep4_H&E
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Brain_OFB_polb_rep5_H&E
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Brain_OFB_wt_rep5_H&E
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Spatial pattern pathway has Marcks envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
MarcksGOBP_Cytoskeleton_OrganizationMouseSpinal cordL7bCN02_E1 8.3e-06
MarcksGOBP_Actin_Crosslink_FormationMouseSpinal cordL7CN45_C1 1.5e-07
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseSpinal cordL7CN45_C1 4.0e-08
MarcksGOBP_Central_Nervous_System_DevelopmentMouseSpinal cordL7CN45_C1 5.5e-10
MarcksGOBP_Actin_Filament_Based_ProcessMouseSpinal cordL7CN47_C1 3.4e-06
MarcksGOBP_Actin_Filament_OrganizationMouseSpinal cordL8CN17_E1 2.1e-07
MarcksGOBP_Actin_Crosslink_FormationMouseBrainrep_37 7.4e-05
MarcksGOBP_Actin_Filament_Based_ProcessMouseBrainrep_1 2.1e-24
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseBrainrep_1 3.9e-26
MarcksGOBP_Actin_Filament_OrganizationMouseBrainrep_1 4.6e-31
MarcksGOBP_Central_Nervous_System_DevelopmentMouseBrainrep_1 8.6e-30
MarcksGOBP_Cytoskeleton_OrganizationMouseBrainrep_1 1.1e-11
MarcksGOBP_Supramolecular_Fiber_OrganizationMouseBrainrep_3 6.7e-78
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseEmbryorep_14 2.6e-12
MarcksGOBP_Central_Nervous_System_DevelopmentMouseEmbryorep_13.0e-261
MarcksGOBP_Supramolecular_Fiber_OrganizationMouseEmbryorep_3 0.0e+00
MarcksGOBP_Central_Nervous_System_DevelopmentMouseKidneyNep 4.2e-26
MarcksGOBP_Actin_Crosslink_FormationMouseKidneyrep_2 4.3e-37
MarcksGOBP_Actin_Filament_Based_ProcessMouseKidneyrep_22.6e-107
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseKidneyrep_2 2.1e-63
MarcksGOBP_Actin_Filament_OrganizationMouseKidneyrep_2 4.0e-81
MarcksGOBP_Central_Nervous_System_DevelopmentMouseKidneyrep_2 1.3e-23
MarcksGOBP_Cytoskeleton_OrganizationMouseKidneyrep_2 1.5e-44
MarcksGOBP_Supramolecular_Fiber_OrganizationMouseKidneyrep_2 9.5e-65
MarcksGOBP_Actin_Crosslink_FormationMouseLiverCN16-D2 1.3e-09
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseLiverCN16-E1 4.4e-13
MarcksGOBP_Actin_Crosslink_FormationMouseLiverrep_15 3.0e-17
MarcksGOBP_Central_Nervous_System_DevelopmentMouseLiverrep_16 8.2e-15
MarcksGOBP_Actin_Crosslink_FormationMouseLymphMS-1 2.2e-11
MarcksGOBP_Actin_Filament_Based_ProcessMouseLymphMS-1 1.4e-10
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseLymphMS-1 4.5e-10
MarcksGOBP_Actin_Filament_OrganizationMouseLymphMS-1 4.2e-11
MarcksGOBP_Central_Nervous_System_DevelopmentMouseLymphMS-1 3.8e-07
MarcksGOBP_Cytoskeleton_OrganizationMouseLymphMS-1 1.8e-13
MarcksGOBP_Supramolecular_Fiber_OrganizationMouseLymphMS-1 1.5e-12
MarcksGOBP_Actin_Crosslink_FormationMouseBrainHP_ad_rep3 7.3e-24
MarcksGOBP_Actin_Filament_Bundle_OrganizationMouseBrainHP_ad_rep7 8.2e-09
MarcksGOBP_Central_Nervous_System_DevelopmentMouseBrainHP_ad_rep7 2.3e-07
MarcksGOBP_Cytoskeleton_OrganizationMouseBrainHP_ad_rep7 5.3e-08
MarcksGOBP_Supramolecular_Fiber_OrganizationMouseBrainHP_ad_rep7 5.2e-07
MarcksGOBP_Actin_Filament_Based_ProcessMouseBrainHP_polb_rep9 3.0e-07

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Marcks function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Marcks function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Marcks envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Marcks

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Marcks

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource